Quick answers
- What is Alka Seltzer?
- Alka Seltzer is a brand name of Aspirin, Anhydrous citric acid, aspirin and sodium bicarbonate, Calcium carbonate, Acetaminophen, chlorpheniramine, dextromethorphan and phenylephrine, Citric acid and sodium bicarbonate, Aspirin and caffeine, Calcium carbonate and dimethicone, Aspirin, dextromethorphan, doxylamine and phenylephrine, Acetaminophen and dextromethorphan and Aspirin, chlorpheniramine and phenylephrine, an over-the-counter medicine. The FDA NDC Directory lists 24 Alka Seltzer products in 13 strengths and forms.
- Who makes Alka Seltzer?
- Bayer HealthCare LLC. lists 15 of the 24 Alka Seltzer products in the FDA NDC Directory.
- Is there a generic or store brand of Alka Seltzer?
- Yes. The FDA NDC Directory lists 306 other products with the same active ingredients, strength and form as a Alka Seltzer product, 306 of them generic or store brands. Ask your pharmacist whether one is right for you.
- Has Alka Seltzer been recalled?
- No recall linked to Alka Seltzer products (by their NDC code or label) appears in the FDA enforcement reports we use.
What Alka Seltzer is
Each Alka Seltzer product as listed in the FDA NDC Directory, by active ingredient, strength and form, with its official label. “Same medicine, other names” counts the other products with exactly the same active ingredients, strength and form (generic versions, store brands and other brands); inactive ingredients can differ.
Aspirin · over-the-counter medicine
| Strength and form | Product names | Same medicine, other names | Label |
|---|---|---|---|
| aspirin 325 mg tablet, effervescent (oral) | Alka-Seltzer Original Flavor, Alka-Seltzer Pain Relief, Alka-Seltzer | 16 products, 16 companies | DailyMed |
Its page quotes the Drug Facts label and lists every brand and store brand: Aspirin →
Anhydrous citric acid, aspirin and sodium bicarbonate · over-the-counter medicine
| Strength and form | Product names | Same medicine, other names | Label |
|---|---|---|---|
| anhydrous citric acid 1000 mg · aspirin 325 mg · sodium bicarbonate 1916 mg tablet, effervescent (oral) | Alka-Seltzer Original, Alka-Seltzer Heartburn and Pain | 24 products, 22 companies | DailyMed |
| anhydrous citric acid 1000 mg · aspirin 500 mg · sodium bicarbonate 1985 mg granule, effervescent (oral) | Alka-Seltzer Extra Strength | None listed | DailyMed |
Its page quotes the Drug Facts label and lists every brand and store brand: Anhydrous citric acid, aspirin and sodium bicarbonate →
Calcium carbonate · over-the-counter medicine
| Strength and form | Product names | Same medicine, other names | Label |
|---|---|---|---|
| calcium carbonate 750 mg gum, chewing (oral) | Alka-Seltzer Heartburn Relief Peppermint | 1 product, 1 company | DailyMed |
| calcium carbonate 750 mg tablet, chewable (oral) | Alka-Seltzer Heartburn ReliefChews | 216 products, 69 companies | DailyMed |
Its page quotes the Drug Facts label and lists every brand and store brand: Calcium carbonate →
Acetaminophen, chlorpheniramine, dextromethorphan and phenylephrine · over-the-counter medicine
| Strength and form | Product names | Same medicine, other names | Label |
|---|---|---|---|
| acetaminophen 250 mg · chlorpheniramine maleate 2 mg · dextromethorphan hydrobromide 10 mg · phenylephrine hydrochloride 5 mg tablet, effervescent (oral) | Alka-Seltzer Plus Cold and Flu | 7 products, 4 companies | DailyMed |
Its page quotes the Drug Facts label and lists every brand and store brand: Acetaminophen, chlorpheniramine, dextromethorphan and phenylephrine →
Citric acid and sodium bicarbonate · over-the-counter medicine
| Strength and form | Product names | Same medicine, other names | Label |
|---|---|---|---|
| citric acid monohydrate 1000 mg · sodium bicarbonate 1650 mg tablet, effervescent (oral) | Alka-Seltzer Heartburn Relief Lemon Lime | None listed | DailyMed |
| citric acid monohydrate 1000 mg · sodium bicarbonate 1940 mg tablet, effervescent (oral) | Alka-Seltzer Heartburn | None listed | DailyMed |
Its page quotes the Drug Facts label and lists every brand and store brand: Citric acid and sodium bicarbonate →
Aspirin and caffeine · over-the-counter medicine
| Strength and form | Product names | Same medicine, other names | Label |
|---|---|---|---|
| aspirin 500 mg · caffeine 65 mg tablet, effervescent (oral) | Alka-Seltzer Hangover Relief, Alka-Seltzer Extra Strength Pain Relief | None listed | DailyMed |
Its page quotes the Drug Facts label and lists every brand and store brand: Aspirin and caffeine →
Calcium carbonate and dimethicone · over-the-counter medicine
| Strength and form | Product names | Same medicine, other names | Label |
|---|---|---|---|
| calcium carbonate 750 mg · dimethicone 80 mg tablet, chewable (oral) | Alka-Seltzer Kids Tummy ReliefChews | 12 products, 8 companies | DailyMed |
Its page quotes the Drug Facts label and lists every brand and store brand: Calcium carbonate and dimethicone →
Aspirin, dextromethorphan, doxylamine and phenylephrine · over-the-counter medicine
| Strength and form | Product names | Same medicine, other names | Label |
|---|---|---|---|
| aspirin 500 mg · dextromethorphan hydrobromide 10 mg · doxylamine succinate 6.25 mg · phenylephrine bitartrate 7.8 mg tablet, effervescent (oral) | Alka-Seltzer Plus Cold Night | 1 product, 1 company | DailyMed |
Its page quotes the Drug Facts label and lists every brand and store brand: Aspirin, dextromethorphan, doxylamine and phenylephrine →
Acetaminophen and dextromethorphan · over-the-counter medicine
| Strength and form | Product names | Same medicine, other names | Label |
|---|---|---|---|
| acetaminophen 162.5 mg · dextromethorphan hydrobromide 5 mg tablet, chewable (oral) | ALKA SELTZER COLD Cold and Cough Fast | 2 products, 2 companies | DailyMed |
Its page quotes the Drug Facts label and lists every brand and store brand: Acetaminophen and dextromethorphan →
Aspirin, chlorpheniramine and phenylephrine · over-the-counter medicine
| Strength and form | Product names | Same medicine, other names | Label |
|---|---|---|---|
| aspirin 325 mg · chlorpheniramine maleate 2 mg · phenylephrine bitartrate 7.8 mg tablet, effervescent (oral) | Alka-Seltzer Plus Cold Orange Zest | 27 products, 17 companies | DailyMed |
Its page quotes the Drug Facts label and lists every brand and store brand: Aspirin, chlorpheniramine and phenylephrine →
FDA approval
Alka Seltzer products are sold under an FDA over-the-counter monograph: rules that set the allowed active ingredients, strengths and label wording, so these products do not need an individual FDA approval.
Companies that list Alka Seltzer
The company named on the package (holder, repackager or distributor), as listed in the FDA NDC Directory, with its number of Alka Seltzer products.
- Bayer HealthCare LLC.15 products
- Lil' Drug Store Products, Inc.5 products
- Select Consumer Group2 products
- R J General Corporation1 product
- Navajo Manufacturing Company Inc.1 product
Recalls
No recall linked to Alka Seltzer products (by their NDC code or label) appears in the FDA enforcement reports.
Sources
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- NADAC (National Average Drug Acquisition Cost) 2026 — Centers for Medicare & Medicaid Services (CMS), data.medicaid.gov, list of November 4, 2026, retrieved November 7, 2026
Which names get a brand page: a name the NDC Directory lists for a medicine, held by one company (the FDA application holder, or the company named on most of its products), that is not just a description, and that is not the only product of its medicine.