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Over-the-counter medicine · no prescription needed

Citric acid and sodium bicarbonate

Purpose on the label: Antacid Antacid

Heartburn and stomach

Official FDA data, not advice

The label text is quoted exactly as the company filed it with the U.S. Food and Drug Administration (FDA), with a link to the official copy. The list of brands comes from the FDA NDC Directory.

This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.

If someone may have taken too much, call Poison Help: 1‑800‑222‑1222. In an emergency, call 911.

Quick answers

What is Citric acid and sodium bicarbonate used for?
The Drug Facts label of Sal de Uvas Picot (RB Health Mexico, S.A. de C.V.) lists these uses: for the relief of: heartburn sour stomach acid indigestion upset stomach associated with these symptoms.
Do I need a prescription for Citric acid and sodium bicarbonate?
No. The products on this page are sold without a prescription (over the counter).
Is a store brand the same as the name brand?
Products listed together below have the same active ingredients, in the same amount and the same form, as registered with the FDA. Inactive ingredients (such as colors, flavors and fillers) and package sizes can differ. Compare the “Active ingredient” box on both packages, and ask a pharmacist if you are not sure.
Has Citric acid and sodium bicarbonate been recalled?
No recall linked to these products appears in the FDA enforcement reports we use.

Drug Facts label

Every over-the-counter medicine must carry a “Drug Facts” box in the same order, set by FDA rules. Below is the label of one product for each common strength and form, quoted word for word. Your own package can differ (for example, children’s products have other directions): always follow the label on your package.

Sal de Uvas Picot · RB Health Mexico, S.A. de C.V.

Citric acid monohydrate 1948.5 mg · Sodium bicarbonate 2485 mg, granule, effervescent (oral)

Active ingredient (in each packet)

Purposes Citric acid 1948.5 mg Antacid Sodium bicarbonate (heat-treated) 2485 mg Antacid

Purpose

Active ingredients (in each packet) Purposes Citric acid 1948.5 mg Antacid Sodium bicarbonate (heat-treated) 2485 mg Antacid

Uses

for the relief of: heartburn sour stomach acid indigestion upset stomach associated with these symptoms

Warnings

Do not take more than directed in a 24-hour period or use the maximum dosage of this product more than 2 weeks, except under the advice and supervision of a physician.

Ask a doctor before use if

you have a sodium-restricted diet

Ask a doctor or pharmacist before use if

you are presently taking a prescription drug. Antacids may interact with certain prescription drugs.

If pregnant or breast-feeding

ask a health professional before use.

Keep out of reach of children

In case of overdose, get medical help or contact a Poison Control Center immediately.

Directions

fully dissolve one packet in ½ glass (4 fl oz) of water.

Adults and children 12 to 60 years of age1 packet every 4 hours, or as directed by a doctorDo not exceed 4 packets in 24 hours
Adults 60 years of age and over1 packet every 4 hours, or as directed by a doctorDo not exceed 3 packets in 24 hours
Children under 12 years of ageAsk a doctor

Inactive ingredients

silicon dioxide, sucrose, tartaric acid.

Questions?

1-844-700-9956

— FDA label of Sal de Uvas Picot, RB Health Mexico, S.A. de C.V., effective November 15, 2024. See the official label on DailyMed →

Alka-Seltzer Heartburn Relief Extra Strength · Bayer Healthcare LLC

Citric acid monohydrate 1000 mg · Sodium bicarbonate 1976 mg, tablet, effervescent (oral)

Active ingredient

Anhydrous citric acid 1000 mg Sodium bicarbonate (heat-treated) 1976 mg

Purpose

Antacid Antacid

Uses

for the relief of heartburn acid indigestion sour stomach upset stomach associated with these symptoms

Warnings

Do not use

if you have ever had an allergic reaction to this product or any of its ingredients

Ask a doctor before use if

you have a sodium-restricted diet

Ask a doctor or pharmacist before use if

you are presently taking a prescription drug. Antacids may interact with certain prescription drugs.

When using this product

do not exceed recommended dosage

Stop use and ask a doctor if

you have taken the maximum dose for 2 weeks

If pregnant or breast-feeding

ask a health professional before use.

Keep out of reach of children

Directions

fully dissolve 2 tablets in 4 ounces of water before taking

adults and children 12 years and over2 tablets every 4 hours as needed, or as directed by a doctordo not exceed 8 tablets in 24 hours
adults 60 years and over2 tablets every 4 hours as needed, or as directed by a doctordo not exceed 4 tablets in 24 hours
children under 12 yearsconsult a doctor

Other information

  • each tablet contains: sodium 586 mg
  • store at room temperature. Avoid excessive heat.
  • Alka-Seltzer Extra Strength in water contains the antacid sodium citrate as the principal active ingredient

Inactive ingredients

magnesium stearate, mannitol

Questions?

1-800-986-0369 (Mon – Fri 9AM – 5PM EST)

— FDA label of Alka-Seltzer Heartburn Relief Extra Strength, Bayer Healthcare LLC, effective March 11, 2025. See the official label on DailyMed →

Alka-Seltzer Heartburn Relief Lemon Lime · Bayer Healthcare LLC

Citric acid monohydrate 1000 mg · Sodium bicarbonate 1650 mg, tablet, effervescent (oral)

Active ingredient

Anhydrous citric acid 1000 mg Sodium bicarbonate (heat-treated) 1650 mg

Purpose

Antacid Antacid

Uses

for the relief of heartburn acid indigestion sour stomach upset stomach associated with these symptoms

Warnings

Do not use

if you have ever had an allergic reaction to this product or any of its ingredients

Ask a doctor before use if

you have a sodium-restricted diet

Ask a doctor or pharmacist before use if

you are presently taking a prescription drug. Antacids may interact with certain prescription drugs.

When using this product

do not exceed recommended dosage

Stop use and ask a doctor if

you have taken the maximum dose for 2 weeks

If pregnant or breast-feeding

ask a health professional before use.

Keep out of reach of children

Directions

fully dissolve 2 tablets in 4 ounces of water before taking

adults and children 12 years and over2 tablets every 4 hours as needed, or as directed by a doctordo not exceed 8 tablets in 24 hours
adults 60 years and over2 tablets every 4 hours as needed, or as directed by a doctordo not exceed 4 tablets in 24 hours
children under 12 yearsconsult a doctor

Other information

  • each tablet contains: sodium 489 mg
  • phenylketonurics: contains phenylalanine 4.5 mg per tablet
  • store at room temperature. Avoid excessive heat.
  • Alka-Seltzer Lemon Lime in water contains the antacid sodium citrate as the principal active ingredient

Inactive ingredients

aspartame, flavor, magnesium stearate, mannitol

Questions?

1-800-986-0369 (Mon – Fri 9AM – 5PM EST)

— FDA label of Alka-Seltzer Heartburn Relief Lemon Lime, Bayer Healthcare LLC, effective April 1, 2025. See the official label on DailyMed →

Alka-Seltzer Heartburn · Bayer HealthCare LLC.

Citric acid monohydrate 1000 mg · Sodium bicarbonate 1940 mg, tablet, effervescent (oral)

Active ingredient (in each tablet)

Anhydrous citric acid 1000 mg Sodium bicarbonate (heat-treated) 1940 mg

Purpose

Active ingredients (in each tablet)...................................................................................Purpose Anhydrous citric acid 1000 mg....................................................................................... Antacid Sodium bicarbonate (heat-treated) 1940 mg ..............................................................Antacid

Uses

for the relief of heartburn acid indigestion upset stomach associated with these symptoms

Warnings

Do not use

Do not use

if you have ever had an allergic reaction to this product or any of its ingredients

Ask a doctor before use if

you have

Ask a doctor before use if

you have a sodium-restricted diet

Ask a doctor or pharmacist before use if

you are

Ask a doctor or pharmacist before use if

you are presently taking a prescription drug. Antacids may interact with certain prescription drugs.

When using this product

When using this product

do not exceed recommended dosage Stop use and ask a doctor

Stop use and ask a doctor if

you have taken the maximum dose for 2 weeks

If pregnant or breast-feeding

If pregnant or breast-feeding

ask a health professional before use.

Keep out of reach of children

Keep out of reach of children

Keep out of reach of children

Directions

fully dissolve 2 tablets in 4 ounces of water before taking

adults and children 12 years and over2 tablets every 4 hours as needed, or as directed by a doctordo not exceed 8 tablets in 24 hours
adults 60 years and over2 tablets every 4 hours as needed, or as directed by a doctordo not exceed 4 tablets in 24 hours
children under 12 yearsconsult a doctor

Other information

each tablet contains: sodium 575 mg phenylketonurics: contains phenylalanine 5.6 mg per tablet store at room temperature. Avoid excessive heat. Alka-Seltzer Heartburn in water contains the antacid sodium citrate as the principal active ingredient

Inactive ingredients

acesulfame potassium, aspartame, flavors, magnesium stearate, mannitol

Questions?

Questions or comments? 1-800-986-0369 (Mon – Fri 9AM – 5PM EST)

— FDA label of Alka-Seltzer Heartburn, Bayer HealthCare LLC., effective December 4, 2025. See the official label on DailyMed →

This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.

Same medicine, other brands

Each group lists the products that have exactly the same active ingredients, in the same amount and form, as registered with the FDA (NDC Directory). A store brand in the same group has the same medicine as the name brand; inactive ingredients, flavors and package sizes can differ. Each product links to its own official label.

Citric acid monohydrate 1948.5 mg · Sodium bicarbonate 2485 mg · granule, effervescent (oral) · 2 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Sal de Uvas Picot Navajo Manufacturing Company Inc. —
Sal de Uvas Picot RB Health Mexico, S.A. de C.V. DailyMed
Citric acid monohydrate 1000 mg · Sodium bicarbonate 1976 mg · tablet, effervescent (oral) · 1 product

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Alka-Seltzer Heartburn Relief Extra Strength Bayer Healthcare LLC DailyMed
Citric acid monohydrate 1.9485 g · Sodium bicarbonate 2.485 g · granule, effervescent (oral) · 1 product
Brand or product nameCompany on the labelLabel
Sal De Uvas Picot Navajo Manufacturing Company Inc. —
Citric acid monohydrate 1000 mg · Sodium bicarbonate 1650 mg · tablet, effervescent (oral) · 1 product

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Alka-Seltzer Heartburn Relief Lemon Lime Bayer Healthcare LLC DailyMed
Citric acid monohydrate 1000 mg · Sodium bicarbonate 1940 mg · tablet, effervescent (oral) · 1 product

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Alka-Seltzer Heartburn Bayer HealthCare LLC. DailyMed

Companies that sell this medicine

The company named on the package (maker or distributor), as listed in the FDA NDC Directory, with its number of over-the-counter products of this medicine.

  • Bayer HealthCare LLC.3 products
  • Navajo Manufacturing Company Inc.2 products
  • RB Health Mexico, S.A. de C.V.1 product

Recalls

No recall linked to these products (by their NDC code or label) appears in the FDA enforcement reports.

Next steps

Sources

  1. Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  2. NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  3. Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
  4. FDA rule for the Drug Facts label (21 CFR 201.66)

Only medicines marketed under FDA rules for nonprescription drugs (an FDA monograph or an FDA approval) are listed. Homeopathic products are not listed: the FDA does not evaluate them for safety or effectiveness.

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