Quick answers
- What is Sodium chloride, sodium lactate, potassium chloride, and calcium chloride used for?
- The FDA-approved label (Lactated Ringers, B. Braun Medical Inc., November 5, 2025) says: “Lactated Ringer’s Injection is indicated for use as a source of water and electrolytes or as an alkalinizing agent in adults and pediatric patients. Lactated Ringer’s Injection is indicated for use as a source of water and electrolytes or as an alkalinizing agent in adults and pediatric patients.” This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or change any medicine.
- Does Sodium chloride, sodium lactate, potassium chloride, and calcium chloride have a boxed warning?
- No. None of the 15 FDA labels we found for this medicine has a boxed warning.
- Is there a shortage of Sodium chloride, sodium lactate, potassium chloride, and calcium chloride?
- No current shortage is listed by the FDA for the products of this medicine (FDA data from October 30, 2026).
- Has Sodium chloride, sodium lactate, potassium chloride, and calcium chloride been recalled?
- FDA enforcement reports list 7 recalls of products of this medicine; the newest started August 12, 2026 (Class I). A recall usually concerns specific lots, not every product.
- Who makes Sodium chloride, sodium lactate, potassium chloride, and calcium chloride?
- 8 companies list prescription products of Sodium chloride, sodium lactate, potassium chloride, and calcium chloride in the FDA NDC Directory, including B. Braun Medical Inc., Fresenius Kabi USA, LLC and Asclemed USA, Inc..
What Sodium chloride, sodium lactate, potassium chloride, and calcium chloride is used for
Quoted from the “Indications and Usage” section of the FDA-approved label.
Lactated Ringer’s Injection is indicated for use as a source of water and electrolytes or as an alkalinizing agent in adults and pediatric patients. Lactated Ringer’s Injection is indicated for use as a source of water and electrolytes or as an alkalinizing agent in adults and pediatric patients.
— FDA label: Lactated Ringers, B. Braun Medical Inc., effective November 5, 2025. Read the full label on DailyMed →
The FDA has 15 labels for products of this medicine (different makers and forms); uses can differ between them. Check the label that comes with your own medicine.
This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or change any medicine.
Boxed warning
A boxed warning (“black box”) is the FDA’s strongest warning on a drug label, for serious or life-threatening risks.
The label quoted above has no boxed warning.
0 of 15 FDA labels for this medicine have a boxed warning.
Forms and how it is given
| Dosage forms | Injection, solution · Irrigant · Solution |
|---|---|
| Route | Intravenous · Irrigation |
| Prescription products | 17 in the FDA NDC Directory |
| Brand names | Lactated Ringers, Lactated Ringers Irrigation |
What pharmacies pay (NADAC)
The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.
This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.
| Strength and form | Generic or brand | Pharmacies pay |
|---|---|---|
| calcium chloride 0.02% · potassium chloride 0.03% · sodium chloride 0.6% · sodium lactate 0.31% injection, solution | Generic | $0.0040 per mL |
| calcium chloride 20 mg/100 mL · potassium chloride 30 mg/100 mL · sodium chloride 600 mg/100 mL · sodium lactate 310 mg/100 mL injection, solution | Generic | $0.0020–$0.0040 per mL 4 packages, lowest to highest |
NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.
Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →
Companies that list this medicine
Labelers in the FDA NDC Directory: the company named on the package (maker or distributor), with the number of prescription products.
- B. Braun Medical Inc.5 products
- Fresenius Kabi USA, LLC4 products
- Asclemed USA, Inc.2 products
- Baxter Healthcare Company2 products
- ICU Medical Inc.2 products
- Becton Dickinson and Company1 product
- HF Acquisition Co LLC, DBA HealthFirst1 product
- Baxter Healthcare Corporation1 product
FDA approval history
- NDA: New Drug Application: how a new (usually brand-name) medicine is approved.
- ANDA: Abbreviated New Drug Application: how a generic version is approved.
| Application | Sponsor | Approved | Later changes approved |
|---|---|---|---|
| NDA016682 LACTATED RINGER'S IN PLASTIC CONTAINER | Baxter Hlthcare | March 22, 1971 | 76, latest November 5, 2025 2025: Labeling · 2024: Labeling · 2019: Labeling |
| NDA017641 LACTATED RINGER'S IN PLASTIC CONTAINER | Otsuka Icu Medcl | January 26, 1976 | 110, latest June 14, 2016 2016: Manufacturing (CMC) · 2014: Manufacturing (CMC) · 2014: Manufacturing (CMC) |
| NDA018494 LACTATED RINGER'S IN PLASTIC CONTAINER | Baxter Hlthcare | February 19, 1982 | 14, latest September 30, 2014 2014: Manufacturing (CMC) · 2014: Manufacturing (CMC) · 2013: Manufacturing (CMC) |
| NDA018681 LACTATED RINGER'S IN PLASTIC CONTAINER | B Braun | December 27, 1982 | 15, latest September 2, 2014 2014: Manufacturing (CMC) · 2007: Labeling · 2002: Manufacturing (CMC) |
| NDA018921 LACTATED RINGER'S IN PLASTIC CONTAINER | Baxter Hlthcare | April 3, 1984 | 20, latest September 29, 2015 2015: Labeling · 2014: Manufacturing (CMC) · 2001: Manufacturing (CMC) |
| NDA019416 LACTATED RINGER'S IN PLASTIC CONTAINER | Otsuka Icu Medcl | January 17, 1986 | 14, latest August 15, 2014 2014: Manufacturing (CMC) · 1999: Labeling · 1997: Manufacturing (CMC) |
| NDA019632 LACTATED RINGER'S IN PLASTIC CONTAINER | B Braun | February 29, 1988 | 21, latest November 5, 2025 2025: Labeling · 2021: Labeling · 2016: Manufacturing (CMC) |
Generic approvals (1)
- ANDA209338Fresenius Kabi USA · January 28, 2019
Shortage status
The FDA drug shortage list does not show these products.
Recalls
From FDA enforcement reports, matched by the product’s NDC code. A recall usually covers specific lots only: check the lot number on your package and ask your pharmacist. Do not stop a medicine on your own.
-
August 12, 2026 · Class I · Ongoing · D-0832-2026
Presence of Particulate matter.
Lactated Ringer's Injection USP, 1000 mL EXCEL container, Rx only, L7500, B. Braun Medical, Inc., Bethlehem, PA 18018-3524 USA, NDC 0264-7750-00 — B BRAUN MEDICAL INC
-
April 28, 2026 · Class I · Ongoing · D-0540-2026
Presence of Particulate Matter.
Lactated Ringer's Injection USP, 1000 mL container, Rx only, B. Braun Medical, Inc., Bethlehem, PA 18018-3524 USA, NDC 0264-7750-07. — B BRAUN MEDICAL INC
-
April 2, 2026 · Class II · Ongoing · D-0498-2026
Lack of Assurance of Sterility; potential for leakage from the diaphragm port once the foil is removed.
LACTATED RINGER'S IRRIGATION, 3000 mL bags, Sterile, Ex only, B. Braun Medical Inc., Bethlehem, PA 18018-3524, USA, NDC: 0264-7389-60. — B BRAUN MEDICAL INC
-
August 18, 2025 · Class I · Ongoing · D-0627-2025
Presence of Particulate Matter
Lactated Ringers's Injection USP, 1000 mL container, Rx only, B. Braun Medical, Inc., Bethlehem, PA 18018-3524 USA, NDC 0264-7750-07 — B BRAUN MEDICAL INC
-
August 4, 2025 · Class II · Ongoing · D-0585-2025
Lack of Assurance of Sterility; potential for fluid leakage at one of the weld sites.
Lactated Ringer's Injection USP, L 7500, 1000mL Excel Container, Rx Only, Sterile, nonpyrogenic, single dose container, B. Braun Medical Inc., Bethlehem, PA 18018, NDC 0264-7750-00. — B BRAUN MEDICAL INC
-
March 22, 2024 · Class II · Terminated · D-0431-2024
Lack of assurance of sterility: bags have the potential to leak..
Lactated Ringer's Injection USP, 1000mL, EXCEL CONTAINER, Rx only, B.Braun Medical Inc., Bethlehem, PA 18018, NDC 0264-7750-00 — B. Braun Medical Inc
-
March 24, 2015 · Class I · Terminated · D-1211-2015
Presence of Particulate Matter: Products recalled due to presence of particulate matter (metal)
Lactated Ringers Injection, USP, 250mL VIAFELX Plastic bags, Manufactured by Baxter Healthcare Corporation 65 Pitts Station Road Marion, North Carolina 28752-7925 for Baxter Healthcare Corporation 1 Baxter Pkwy Deerfield — Baxter Healthcare Corp.
What do the recall classes mean?
Class I: The most serious type: there is a reasonable chance that using the product will cause serious health problems or death.
Class II: Using the product may cause temporary or medically reversible health problems, or the chance of serious problems is remote.
Class III: Using the product is not likely to cause health problems (for example a labeling or packaging issue).
Official identifiers
| RxCUI (RxNorm) | 847627, 847628, 847630 |
|---|---|
| SPL set ID of the quoted label | d3d29c8f-c326-4097-814a-7f4e08c67068 |
| FDA labels (SPL) | 15 |
| FDA applications | NDA016682, NDA017641, NDA018494, NDA018681, NDA018921, NDA019416, NDA019632, 1 ANDA |
| Active ingredients (FDA) | CALCIUM CHLORIDE / POTASSIUM CHLORIDE / SODIUM CHLORIDE / SODIUM LACTATE |
Sources
- FDA-approved label on DailyMed (National Library of Medicine) — Lactated Ringers, B. Braun Medical Inc., effective November 5, 2025; via openFDA, FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- Drug shortages (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
openFDA data is provided by the FDA as is; it may be incomplete. Always rely on the label that comes with your medicine. FDA Enforcement Report search →