Quick answers
- What is Calcium chloride used for?
- The FDA-approved label (Calcium Chloride, Hospira, Inc., February 2, 2026) says: “Calcium Chloride Injection is indicated for the treatment of adult and pediatric patients with acute symptomatic hypocalcemia. Limitations of Use The safety and effectiveness of Calcium Chloride Injection for long-term use has not been established. Calcium Chloride Injection is a form of calcium indicated for the treatment of adult and pediatric and patients with acute symptomatic hypocalcemia. Limitations of Use …” This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or change any medicine.
- Does Calcium chloride have a boxed warning?
- No. None of the 17 FDA labels we found for this medicine has a boxed warning.
- Is there a shortage of Calcium chloride?
- No current shortage is listed by the FDA for the products of this medicine (FDA data from October 30, 2026).
- Has Calcium chloride been recalled?
- No recall linked to the products of this medicine appears in the FDA enforcement reports we use.
- Who makes Calcium chloride?
- 16 companies list prescription products of Calcium chloride in the FDA NDC Directory, including Medical Purchasing Solutions, LLC, Amneal Pharmaceuticals LLC and HF Acquisition Co LLC, DBA HealthFirst.
What Calcium chloride is used for
Quoted from the “Indications and Usage” section of the FDA-approved label.
Calcium Chloride Injection is indicated for the treatment of adult and pediatric patients with acute symptomatic hypocalcemia. Limitations of Use The safety and effectiveness of Calcium Chloride Injection for long-term use has not been established. Calcium Chloride Injection is a form of calcium indicated for the treatment of adult and pediatric and patients with acute symptomatic hypocalcemia. Limitations of Use …
— FDA label: Calcium Chloride, Hospira, Inc., effective February 2, 2026. Read the full label on DailyMed →
The FDA has 17 labels for products of this medicine (different makers and forms); uses can differ between them. Check the label that comes with your own medicine.
This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or change any medicine.
Boxed warning
A boxed warning (“black box”) is the FDA’s strongest warning on a drug label, for serious or life-threatening risks.
The label quoted above has no boxed warning.
0 of 17 FDA labels for this medicine have a boxed warning.
Forms and how it is given
| Dosage forms | Injection, solution · Injection |
|---|---|
| Route | Intravenous · Intraventricular |
| Prescription products | 20 in the FDA NDC Directory |
Companies that list this medicine
Labelers in the FDA NDC Directory: the company named on the package (maker or distributor), with the number of prescription products.
- Medical Purchasing Solutions, LLC2 products
- Amneal Pharmaceuticals LLC2 products
- HF Acquisition Co LLC, DBA HealthFirst2 products
- Remedyrepack Inc.2 products
- Civica, Inc.1 product
- Dr. Reddy's Laboratories Inc.1 product
- PAI Holdings, LLC dba PAI Pharma1 product
- Medefil, Inc.1 product
- Hospira, Inc.1 product
- American Regent, Inc.1 product
- Henry Schein, Inc.1 product
- Eskayef Pharmaceuticals Limited1 product
- Somerset Therapeutics, LLC1 product
- Square Pharmaceuticals PLC.1 product
- International Medication Systems, Limited1 product
- ProPharma Distribution1 product
FDA approval history
- NDA: New Drug Application: how a new (usually brand-name) medicine is approved.
- ANDA: Abbreviated New Drug Application: how a generic version is approved.
| Application | Sponsor | Approved | Later changes approved |
|---|---|---|---|
| NDA021117 CALCIUM CHLORIDE 10% IN PLASTIC CONTAINER | Hospira | January 28, 2000 | 5, latest May 11, 2023 2023: Labeling · 2021: Manufacturing (CMC) · 2018: Labeling |
Generic approvals (7)
- ANDA209088Am Regent · July 27, 2017
- ANDA203477Intl Medication Sys · May 9, 2018
- ANDA211553Medefil Inc · May 1, 2019
- ANDA217524Amneal · July 8, 2024
- ANDA219342Pharmazone · November 27, 2024
- ANDA218133Somerset · December 17, 2024
- ANDA217463Square Pharms PLC · September 29, 2025
Shortage status
The FDA drug shortage list does not show these products.
Recalls
No recall linked to these products (by their NDC code) appears in the FDA enforcement reports.
Official identifiers
| RxCUI (RxNorm) | 828525, 828527 |
|---|---|
| SPL set ID of the quoted label | c4c65e48-85f8-4dcf-6281-06e40959cc79 |
| FDA labels (SPL) | 17 |
| FDA applications | NDA021117, 7 ANDA |
| Active ingredients (FDA) | CALCIUM CHLORIDE |
Sources
- FDA-approved label on DailyMed (National Library of Medicine) — Calcium Chloride, Hospira, Inc., effective February 2, 2026; via openFDA, FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- Drug shortages (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
openFDA data is provided by the FDA as is; it may be incomplete. Always rely on the label that comes with your medicine. FDA Enforcement Report search →