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Prescription medicine

Anticoagulant citrate dextrose (acd)

Drug class: Calculi Dissolution Agent, Anti-coagulant

The FDA’s “Established Pharmacologic Class”: the group of medicines that work in a similar way.

Official FDA data, not advice

Everything here comes from the U.S. Food and Drug Administration (FDA): the drug label, the NDC Directory, Drugs@FDA, recall reports and the drug shortage list. Each fact shows its source and date.

This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or change any medicine.

In an emergency, call 911. If someone may have taken too much of a medicine, call Poison Help: 1‑800‑222‑1222.

Anticoagulant citrate dextrose (acd) key facts

Drug class
Calculi Dissolution Agent
Used for
Anticoagulant Citrate Dextrose Solution, Solution A, U.S.P. (source)
Prescription or over the counter
Prescription (Rx)
Generic available
No generic listed by the FDA
Latest FDA recall
None listed

Sources: FDA label (February 14, 2023); FDA NDC Directory (October 30, 2026); FDA enforcement reports (October 27, 2026). Not medical advice.

Quick answers

What is Anticoagulant citrate dextrose (acd) used for?
The FDA-approved label (Anticoagulant Citrate Dextrose A, Citra Labs LLC, February 14, 2023) says: “Anticoagulant Citrate Dextrose Solution, Solution A, U.S.P. (ACD-A), is intended for use as an anticoagulant in the extracorporeal blood processing with Autologous PRP Systems in production of platelet rich plasma (PRP). Refer to the manufacturer's Operator's Manual of the Autologous PRP System for the Directions for Use.” This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or change any medicine.
What are the side effects of Anticoagulant citrate dextrose (acd)?
The “Adverse Reactions” section of the FDA label (Anticoagulant Citrate Dextrose A, Citra Labs LLC, February 14, 2023) begins: “Not applicable. This product is used as an anticoagulant in the extracorporeal blood processing with Autologous PRP Systems in production of platelet rich plasma (PRP).” This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or change any medicine.
Does Anticoagulant citrate dextrose (acd) have a boxed warning?
No. None of the 2 FDA labels we found for this medicine has a boxed warning.
Is there a shortage of Anticoagulant citrate dextrose (acd)?
No current shortage is listed by the FDA for the products of this medicine (FDA data from October 30, 2026).
Has Anticoagulant citrate dextrose (acd) been recalled?
No recall linked to the products of this medicine appears in the FDA enforcement reports we use.
Who makes Anticoagulant citrate dextrose (acd)?
2 companies list prescription products of Anticoagulant citrate dextrose (acd) in the FDA NDC Directory, including Fenwal, Inc. and Citra Labs LLC.

What Anticoagulant citrate dextrose (acd) is used for

Quoted from the “Indications and Usage” section of the FDA-approved label.

Anticoagulant Citrate Dextrose Solution, Solution A, U.S.P. (ACD-A), is intended for use as an anticoagulant in the extracorporeal blood processing with Autologous PRP Systems in production of platelet rich plasma (PRP). Refer to the manufacturer's Operator's Manual of the Autologous PRP System for the Directions for Use.

— FDA label: Anticoagulant Citrate Dextrose A, Citra Labs LLC, effective February 14, 2023. Read the full label on DailyMed →

Label quoted: the one for the most common form (solution, extracorporeal), Anticoagulant Citrate Dextrose A, Citra Labs LLC; it covers 1 product in the FDA NDC Directory. The side effects, interactions, dosage and pregnancy quotes below come from this same label.

The FDA has 2 labels for products of this medicine (different makers and forms); uses can differ between them. Check the label that comes with your own medicine.

This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or change any medicine.

Boxed warning

A boxed warning (“black box”) is the FDA’s strongest warning on a drug label, for serious or life-threatening risks.

The label quoted above has no boxed warning.

0 of 2 FDA labels for this medicine have a boxed warning.

Anticoagulant citrate dextrose (acd) side effects

Quoted from the “Adverse Reactions” section of the FDA-approved label. Tell your doctor about any side effect that worries you.

Not applicable. This product is used as an anticoagulant in the extracorporeal blood processing with Autologous PRP Systems in production of platelet rich plasma (PRP).

— FDA label: Anticoagulant Citrate Dextrose A, Citra Labs LLC, effective February 14, 2023. Read the full label on DailyMed →

Anticoagulant citrate dextrose (acd) dosage

Quoted from the “Dosage and Administration” section of the FDA-approved label. Your own dose is the one your doctor prescribes: do not change it on your own.

Refer to the manufacturer's Operator's Manual of the Autologous PRP System for the Directions for Use.

— FDA label: Anticoagulant Citrate Dextrose A, Citra Labs LLC, effective February 14, 2023. Read the full label on DailyMed →

Anticoagulant citrate dextrose (acd) in pregnancy

Quoted from the pregnancy part of the FDA-approved label. Ask your doctor before you take any medicine while pregnant or planning a pregnancy.

Long-term studies in animals have not been performed to evaluate the effects of ACD- A on pregnant women.

— FDA label: Anticoagulant Citrate Dextrose A, Citra Labs LLC, effective February 14, 2023. Read the full label on DailyMed →

When Anticoagulant citrate dextrose (acd) should not be used

Quoted from the “Contraindications” section of the FDA-approved label.

NOT FOR DIRECT INTRAVENOUS INFUSION

— FDA label: Anticoagulant Citrate Dextrose A, Citra Labs LLC, effective February 14, 2023. Read the full label on DailyMed →

Anticoagulant citrate dextrose (acd) overdose

Quoted from the “Overdosage” section of the FDA-approved label. If someone may have taken too much, call Poison Help at 1-800-222-1222 (or 911 in an emergency).

Not applicable. This product is used as an anticoagulant in the extracorporeal blood processing with Autologous PRP systems in production of platelet rich plasma (PRP).

— FDA label: Anticoagulant Citrate Dextrose A, Citra Labs LLC, effective February 14, 2023. Read the full label on DailyMed →

Forms and how it is given

Dosage formsSolution
RouteIntravenous · Extracorporeal
Prescription products2 in the FDA NDC Directory
Brand namesAcd Blood-Pack Units (Pl 146 Plastic), Anticoagulant Citrate Dextrose a

Companies that list this medicine

Labelers in the FDA NDC Directory: the company named on the package (maker or distributor), with the number of prescription products.

FDA approval history

No Drugs@FDA application is linked to these products.

Shortage status

The FDA drug shortage list does not show these products.

FDA Drug Shortages database →

Recalls

No recall linked to these products (by their NDC code) appears in the FDA enforcement reports.

Official identifiers

SPL set ID of the quoted label5bcd261e-ebba-4ecb-af22-e5aaeb04499b
FDA labels (SPL)2
Active ingredients (FDA)ANHYDROUS CITRIC ACID / DEXTROSE MONOHYDRATE / TRISODIUM CITRATE DIHYDRATE

Next steps

Sources

  1. FDA-approved label on DailyMed (National Library of Medicine) — Anticoagulant Citrate Dextrose A, Citra Labs LLC, effective February 14, 2023; via openFDA, FDA data exported October 30, 2026, retrieved October 31, 2026
  2. NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  3. Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  4. Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
  5. Drug shortages (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026

openFDA data is provided by the FDA as is; it may be incomplete. Always rely on the label that comes with your medicine. FDA Enforcement Report search →

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