Quick answers
- What is Pramoxine and zinc acetate used for?
- The Drug Facts label of Calahist Clear (Walgreen Company) lists these uses: Dries the oozing and weeping of poison: ivy; oak; sumac; For the temporary relief of pain and itching associated with; minor skin irritations; rashes due to poison ivy, poison oak, or poison sumac; minor burns; sunburn; minor cuts; scrapes; insect bites.
- Do I need a prescription for Pramoxine and zinc acetate?
- No. The products on this page are sold without a prescription (over the counter).
- Is a store brand the same as the name brand?
- Products listed together below have the same active ingredients, in the same amount and the same form, as registered with the FDA. Inactive ingredients (such as colors, flavors and fillers) and package sizes can differ. Compare the “Active ingredient” box on both packages, and ask a pharmacist if you are not sure.
- Has Pramoxine and zinc acetate been recalled?
- No recall linked to these products appears in the FDA enforcement reports we use.
Drug Facts label
Every over-the-counter medicine must carry a “Drug Facts” box in the same order, set by FDA rules. Below is the label of one product for each common strength and form, quoted word for word. Your own package can differ (for example, children’s products have other directions): always follow the label on your package.
Calahist Clear · Walgreen Company
Pramoxine hydrochloride 10 mg/mL · Zinc acetate 1 mg/mL, lotion (topical)
Active ingredient
Pramoxine HCI 1% Zinc Acetate 0.1%
Purpose
External analgesic Skin protectant
Uses
- Dries the oozing and weeping of poison:
- ivy
- oak
- sumac
- For the temporary relief of pain and itching associated with
- minor skin irritations
- rashes due to poison ivy, poison oak, or poison sumac
- minor burns
- sunburn
- minor cuts
- scrapes
- insect bites
Warnings
- For external use only
- Use only as directed.
When using this product
do not get into eyes
Stop use and ask a doctor if
condition worsens, or if symptoms persist for more than 7 days or clear up and occur again within a few days
Keep out of reach of children
In case of accidental ingestion, seek professional assistance or contact a Poison Control Center (1-800-222-1222) right away.
Directions
shake well before using
- cleanse the skin with soap and water
- let dry before each use
- apply lotion to the affected area using cotton or soft cloth
| adults and children 2 years and older | Not more than 3 to 4 times daily as needed for comfort |
| children under 2 years | Consult a doctor before use |
Inactive ingredients
SD Alcohol 38B 2.5%, camphor, diazolidinyl urea, fragrances, glycerin, hydroxypropyl methylcellulose, methylparaben, polysorbate 80, propylene glycol, propylparaben, purified water
Questions?
1-888-235-2466
— FDA label of Calahist Clear, Walgreen Company, effective October 27, 2023. See the official label on DailyMed →
CVS Itch Relief · CVS Pharmacy
Pramoxine hydrochloride 1% · Zinc acetate 0.1%, spray (topical)
Active ingredient
Pramoxine HCl 1% Zinc Acetate 0.1%
Purpose
Topical analgesic Skin protectant
Uses
temporarily relieves pain and itching associated with: rashes due to posion ivy, poison oak or poison sumac insect bites minor skin irritation minor cuts dries the oozing and weeping of poison ivy, poison oak and poison sumac
Warnings
For external use only Flammable
Do not use
while smoking or near heat or flame Do not apply to wounds or damaged, broken or irritated skin. do not allow contact with eyes or mucous membranes.
When using this product
keep out of eyes (Rinse with water to remove) do not puncture or incinerate. Contents under pressure. do not store at temperatures above 120 degrees F.
Stop use and ask a doctor if
condition worsens or does not improve within 7 days symptoms persist for more than 7 days or clear up and occur again within a few days
If pregnant or breast-feeding
ask a health professional before use.
Keep out of reach of children
and pets. If swallowed, get medical help or contact a Poison Control Center right away.
Directions
shake well. Adults and children 2 years of age and older: apply to affected area not more than 3 to 4 times daily to apply to face, spray into palm of hand and gently apply children under 2 years of age: consult a doctor Store at 68° to 77° F (20° to 25° C).
Inactive ingredients
Avena Sativa (Oat) Meal Extract, Camphor, Citric Acid, Deionized Water, Diazolidinyl Urea, Glycerin, Hydroxypropyl Methylcellulose, Polysorbate 40, Propylene Glycol, SD Alcohol 40-B, Sodium Citrate
— FDA label of CVS Itch Relief, CVS Pharmacy, effective August 7, 2026. See the official label on DailyMed →
TN Dickinsons Pain and Itch Relief · Dickinson Brands Inc.
Pramoxine hydrochloride 0.01 g/mL · Zinc acetate 0.001 g/mL, liquid (topical)
Active ingredient
Purposes Pramoxine Hydrochloride (1.0%) Topical analgesic Zinc Acetate (0.1%) Skin protectant
Purpose
Active ingredients Purposes Pramoxine Hydrochloride (1.0%) Topical analgesic Zinc Acetate (0.1%) Skin protectant
Uses
Temporarily relieves pain and itching associated with: minor skin irritations minor burns sunburn scrapes minor cuts insect bites poison ivy, oak & sumac Dries the oozing and weeping of poison ivy, oak & sumac
Warnings
For external use only
When using this product
do not get into eyes Stop use and ask doctor if condition or symptoms get worse or lasts more than 1 week symptoms clear up and occur again within a few days
Do not use
on deep or puncture wounds animal bites serious burns
Keep out of reach of children
If swallowed, get medical help or contact Poison Control Center right away.
Directions
apply to affected area not more than 3 to 4 times daily children under 2 years of age: do not use, consult a doctor
Inactive ingredients
aloe barbadensis leaf juice, benzoic acid, coco glucoside, witch hazel distillate, propanediol, tocopheryl acetate (vitamin E)
Questions?
TNDickinsons.com 1•888•860•2279
— FDA label of TN Dickinsons Pain and Itch Relief, Dickinson Brands Inc., effective February 5, 2026. See the official label on DailyMed →
Blistex Ivarest Poison Ivy Itch · Blistex Inc.
Pramoxine hydrochloride 1% · Zinc acetate 0.12%, spray (topical)
Active ingredient
Purpose Pramoxine HCl 1.0% (w/w) External Analgesic Zinc Acetate 0.12 % (w/w) Skin Protectant
Purpose
Active ingredients Purpose Pramoxine HCl 1.0% (w/w) External Analgesic Zinc Acetate 0.12 % (w/w) Skin Protectant
Uses
for the temporary relief of pain and itching associated with poison ivy, poison oak, poison sumac, insect bites or minor skin irritations. dries the oozing and weeping of poison: ivy oak sumac
Warnings
For external use only
Do not use
on large areas of the body
When using this product
do not get into eyes
Stop use and ask a doctor if
condition worsens symptoms last more than 7 days or clear up and occur again within a few days
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away.
Directions
do not use more often than directed. as soon as possible after exposure, wash affected area with soap and water. Gently pat dry. apply Ivarest Poison Ivy Itch Spray liberally. wash hands after use. adults and children 2 years and older: apply to affected area not more than 3 to 4 times daily. children under 2 years of age: consult a doctor.
Inactive ingredients
glycerin, PEG-40 hydrogenated castor oil, phenoxyethanol, propylene glycol, purified water, SD alcohol 38-B, sodium citrate
— FDA label of Blistex Ivarest Poison Ivy Itch, Blistex Inc., effective December 11, 2024. See the official label on DailyMed →
Clear Anti Itch · H E B
Pramoxine HCL 10 mg/mL · Zinc acetate 1 mg/mL, lotion (topical)
Active ingredient
Pramoxine HCl 1% Zinc acetate 0.1%
Purpose
External analgesic Skin protectant
Uses
for the temporary relief of pain and itching associated with minor skin irritations and rashes due to poison ivy, poison oak or poison sumac dries the oozing and weeping of poison:
- ivy
- oak
- sumac
Warnings
For external use only
When using this product
do not get into eyes
Stop use and ask a doctor if
condition worsens symptoms last more than 7 days or clear up and occur again within a few days
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away.
Directions
shake well before applying wash affected area of skin adults and children 2 years of age and older: apply to affected area not more than 3 to 4 times daily children under 2 years: ask a doctor
Inactive ingredients
alcohol, benzoic acid, camphor, citric acid, fragrance, glycerin, hydroxypropyl methylcellulose, Lavandula angustifolia (lavender) oil, polysorbate 40, Rosmarinus officinalis (rosemary) leaf oil, sodium citrate, water
Questions?
1-888-593-0593
— FDA label of Clear Anti Itch, H E B, effective June 23, 2026. See the official label on DailyMed →
This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.
Same medicine, other brands
Each group lists the products that have exactly the same active ingredients, in the same amount and form, as registered with the FDA (NDC Directory). A store brand in the same group has the same medicine as the name brand; inactive ingredients, flavors and package sizes can differ. Each product links to its own official label.
Pramoxine hydrochloride 10 mg/mL · Zinc acetate 1 mg/mL · lotion (topical) · 21 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Calaclear | Pharma Nobis, LLC | DailyMed |
| Calaclear | Wal-Mart Stores, Inc. | DailyMed |
| Caladryl Clear | Bausch Health US, LLC | DailyMed |
| Calahist Clear | Walgreen Company | DailyMed |
| Calamine Clear | Cardinal Health, 110 dba Leader | DailyMed |
| Calamine Clear | Pharma Nobis, LLC | DailyMed |
| Caldyphen Clear | Amerisource Bergen | DailyMed |
| Clear Anti Itch | Better Living Brands, LLC | DailyMed |
| Clear Anti Itch | Topco Associates LLC | DailyMed |
| Clear Anti Itch | United Natural Foods, Inc. dba UNFI | DailyMed |
| Clear Anti-Itch | Chain Drug Marketing Association | DailyMed |
| Clear Anti-Itch | Meijer, Inc. | DailyMed |
| Clear Anti-Itch | Nice-Pak Products, LLC | — |
| Clear Anti-Itch | Old East Main Co. | DailyMed |
| Clear Anti-Itch | Perrigo Direct, Inc | DailyMed |
| Clear Anti-Itch | Retail Business Services, LLC | DailyMed |
| CVS Itch Relief | CVS Pharmacy | DailyMed |
| Foster and Thrive Caldyphen Clear | Strategic Sourcing Services, LLC | DailyMed |
| Humco Calaclear | Humco Holding Group, Inc. | DailyMed |
| Rugby Caldyphen Clear | Rugby Laboratories | DailyMed |
| TopCare Calaclear | Topco Associates LLC | DailyMed |
Pramoxine hydrochloride 1% · Zinc acetate 0.1% · spray (topical) · 4 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| CVS Itch Relief | CVS Pharmacy | DailyMed |
| DCH Calaspray Itch Relief | Derma Care Research Labs, LLC | DailyMed |
| Equate Calaspray | Walmart Inc | DailyMed |
| Rite Aid Cala Itch Relief | Rite Aid | DailyMed |
Pramoxine hydrochloride 0.01 g/mL · Zinc acetate 0.001 g/mL · liquid (topical) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| TN Dickinsons Pain and Itch Relief | Dickinson Brands Inc. | DailyMed |
Pramoxine hydrochloride 1% · Zinc acetate 0.12% · spray (topical) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Blistex Ivarest Poison Ivy Itch | Blistex Inc. | DailyMed |
Pramoxine HCL 10 mg/mL · Zinc acetate 1 mg/mL · lotion (topical) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Clear Anti Itch | H E B | DailyMed |
What pharmacies pay (NADAC)
The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.
This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.
| Strength and form | Generic or brand | Pharmacies pay |
|---|---|---|
| pramoxine hydrochloride 10 mg/mL · zinc acetate 1 mg/mL lotion | Generic | $0.0130 per mL |
NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.
Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →
Companies that sell this medicine
The company named on the package (maker or distributor), as listed in the FDA NDC Directory, with its number of over-the-counter products of this medicine.
- CVS Pharmacy2 products
- Pharma Nobis, LLC2 products
- Topco Associates LLC2 products
- Walgreen Company1 product
- Derma Care Research Labs, LLC1 product
- Chain Drug Marketing Association1 product
- Rite Aid1 product
- Meijer, Inc.1 product
- Retail Business Services, LLC1 product
- United Natural Foods, Inc. dba UNFI1 product
- Cardinal Health, 110 dba Leader1 product
- Perrigo Direct, Inc1 product
- Amerisource Bergen1 product
- Humco Holding Group, Inc.1 product
- Old East Main Co.1 product
- Nice-Pak Products, LLC1 product
- Better Living Brands, LLC1 product
- Bausch Health US, LLC1 product
- Dickinson Brands Inc.1 product
- Strategic Sourcing Services, LLC1 product
- Walmart Inc1 product
- Blistex Inc.1 product
- Wal-Mart Stores, Inc.1 product
- Rugby Laboratories1 product
- H E B1 product
Recalls
No recall linked to these products (by their NDC code or label) appears in the FDA enforcement reports.
Next steps
- Find a pharmacy near youA pharmacist can answer questions about this label
- DchBrand page: products, maker and price
- Latest FDA drug recallsPrescription and over-the-counter, newest first
- All over-the-counter medicinesSearch by ingredient, brand or Spanish name
Sources
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- FDA rule for the Drug Facts label (21 CFR 201.66)
Only medicines marketed under FDA rules for nonprescription drugs (an FDA monograph or an FDA approval) are listed. Homeopathic products are not listed: the FDA does not evaluate them for safety or effectiveness.