Quick answers
- What is Histamine and menthol used for?
- The Drug Facts label of Alo Therapeutic Massage (CMI Therapy Solutions) lists these uses: For temporary relief of minor aches and pains associated with backache, arthritis, bruises and sprains..
- Do I need a prescription for Histamine and menthol?
- No. The products on this page are sold without a prescription (over the counter).
- Is a store brand the same as the name brand?
- Products listed together below have the same active ingredients, in the same amount and the same form, as registered with the FDA. Inactive ingredients (such as colors, flavors and fillers) and package sizes can differ. Compare the “Active ingredient” box on both packages, and ask a pharmacist if you are not sure.
- Has Histamine and menthol been recalled?
- No recall linked to these products appears in the FDA enforcement reports we use.
Drug Facts label
Every over-the-counter medicine must carry a “Drug Facts” box in the same order, set by FDA rules. Below is the label of one product for each common strength and form, quoted word for word. Your own package can differ (for example, children’s products have other directions): always follow the label on your package.
Alo Therapeutic Massage · CMI Therapy Solutions
Histamine dihydrochloride 1 mg/mL · Menthol 30 mg/mL, cream (topical)
Active ingredient
Menthol 3.00% Histamine Dihydrochloride 0.100% External Analgesic
Purpose
External Analgesic
Uses
For temporary relief of minor aches and pains associated with backache, arthritis, bruises and sprains.
Warnings
For external use only. Avoid contact with eyes. Do not apply to open wounds or damaged skin. If symptoms persist for more than seven days, discontinue use and consult physician.
Keep out of reach of children
If swallowed, consult physician. Do not bandage tightly. If pregnant or breast feeding, contact physician prior to use.
Directions
Apply directly to affected area. Do not use more than four times per day.
Inactive ingredients
Other Ingredients Aqua (deionized Water), Butylene Glycol, Carbomer, Cetyl Alcohol, Ethylhexylglycerin, Dimethyl Sulfone (MSM), Glyceryl Stearate, Helianthus Annuus (Sunflower) Oil, Mentha Viridis (Spearmint) Oil, Mineral Oil, Parfum (Fragrance), PEG-100 Stearate, Phenoxyethanol, SD-Alcohol 40B, Triethanolamine, Xanthan Gum.
— FDA label of Alo Therapeutic Massage, CMI Therapy Solutions, effective November 10, 2023. See the official label on DailyMed →
Alo Therapeutic Massage Pain Relieving · Theraplex Solutions
Histamine dihydrochloride 0.1% · Menthol 3%, cream (topical)
Active ingredient
Menthol 3.00% Histamine Dihydrochloride 0.100%
Purpose
External Analgesic
Uses
For temporary relief of minor aches and pains associated with backache, arthritis, bruises and sprains.
Warnings
For external use only. Avoid contact with eyes.
- Do not apply to open wounds or damaged skin.
- If symptoms persist for more than seven days, discontinue use and consult physician.
Keep out of reach of children
If swallowed, consult physician.
- If pregnant or breast feeding, contact physician prior to use.
Directions
Apply directly to effected area. Do not use more than four times per day.
Inactive ingredients
Other Ingredients Aqua (Deionized Water), Butylene Glycol, Carbomer, Cetyl Alcohol, Ethylhexylglycerin, Dimethyl Sulfone (MSM), Glyceryl Stearate, Helianthus Annuus (Sunflower) Oil, Mentha Viridis (Spearmint) Oil, Mineral Oil, Parfum (Fragrance), PEG-100 Stearate, Phenoxyethanol, SD-Alcohol 40B, Triethanolamine, Xanthan Gum.
— FDA label of Alo Therapeutic Massage Pain Relieving, Theraplex Solutions, effective November 10, 2023. See the official label on DailyMed →
DR. MIKES Ponos Pain Relief Cream Roll-On · Dr. Mike's Vitamins, LLC
Histamine dihydrochloride 0.03% · Menthol 3%, cream (topical)
Active ingredient
Histamine DHCl 0.03 % Menthol 3% Purpose Topical Analgesic
Purpose
Topical Analgesic
Uses
For the temporary relief of minor aches and pains of muscles and joints, associated with simple backache, arthritis, strains, bruises, and sprains.
Warnings
For external use only
- apply to wounds or damaged skin.
- bandage tightly. Do not
When using this product
Avoid contact with the eyes
Stop use and ask a doctor if
condition worsens, or if symptoms persist for more than 7 days or clear up and occur again within a few days.
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away.
If pregnant or breast-feeding
ask a health professional before use
Directions
Adults and children 2 years of age and older: Apply to affected area not more than 3 to 4 times daily. Children under 2 years of age: consult a doctor.
Inactive ingredients
Aloe Barbadensis Leaf (Aloe Vera Gel) Juice, Aqua (Deionized Water), Arnica Montana Flower Extract, Beeswax, Boswellia Serrata Extract, Butyrospermum Parkii (Shea) Butter, Cetearyl Alcohol, Cetearyl Olivate, Cetyl Alcohol, Cetyl Myristoleate, Chamomilla Matricaria (Chamomile) Extract, Citric Acid, Cucumis Sativus (Cucumber) Fruit Extract, Dimethyl Sulfone (DMSO), Gluconolactone, Glycerin, Glyceryl Stearate, Glycyrrhiza Glabra (Licorice) Extract, Helianthus Annuus (Sunflower) Oil, Hypericum Perforatum (St. John's Wort), Mentha Piperita (Peppermint) Oil, Methylsulfonylmethane (MSM), Olea Europaea (Olive) Oil, Pistacia Lentiscus (Mastic) Oil, Sodium Benzoate, Sodium Laurylglucosides Hydroxypropyl sulfonate, Sorbitan Olivate, Stearic Acid, Xanthan Gum, Zemea (Corn) Propanediol, Zingiber Officinalis (Ginger) Oil.
Questions?
Go to www.drmikesvitamins.com
— FDA label of DR. MIKES Ponos Pain Relief Cream Roll-On, Dr. Mike's Vitamins, LLC, effective November 5, 2023. See the official label on DailyMed →
This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.
Same medicine, other brands
Each group lists the products that have exactly the same active ingredients, in the same amount and form, as registered with the FDA (NDC Directory). A store brand in the same group has the same medicine as the name brand; inactive ingredients, flavors and package sizes can differ. Each product links to its own official label.
Histamine dihydrochloride 1 mg/mL · Menthol 30 mg/mL · cream (topical) · 4 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Alo Therapeutic Massage | CMI Therapy Solutions | DailyMed |
Histamine dihydrochloride 0.1% · Menthol 3% · cream (topical) · 2 products
Histamine dihydrochloride 0.03% · Menthol 3% · cream (topical) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| DR. MIKES Ponos Pain Relief Cream Roll-On | Dr. Mike's Vitamins, LLC | DailyMed |
Companies that sell this medicine
The company named on the package (maker or distributor), as listed in the FDA NDC Directory, with its number of over-the-counter products of this medicine.
- CMI Therapy Solutions4 products
- Theraplex Solutions2 products
- Dr. Mike's Vitamins, LLC1 product
Recalls
No recall linked to these products (by their NDC code or label) appears in the FDA enforcement reports.
Sources
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- FDA rule for the Drug Facts label (21 CFR 201.66)
Only medicines marketed under FDA rules for nonprescription drugs (an FDA monograph or an FDA approval) are listed. Homeopathic products are not listed: the FDA does not evaluate them for safety or effectiveness.