Quick answers
- What is Dextromethorphan, phenylephrine and triprolidine used for?
- The Drug Facts label of Triponel (Llorens Pharmaceuticals International Division) lists these uses: helps to control the reflex that causes coughing temporarily relieves nasal congestion due to common cold, hay fever, or other upper respiratory allergies (allergic, rhinitis) temporarily relieves these symptomes due to hay fever or ther upper respiratory allergies runny nose itchy, watery eyes sneexing itching of the nose or throat.
- Do I need a prescription for Dextromethorphan, phenylephrine and triprolidine?
- No. The products on this page are sold without a prescription (over the counter).
- Is a store brand the same as the name brand?
- Products listed together below have the same active ingredients, in the same amount and the same form, as registered with the FDA. Inactive ingredients (such as colors, flavors and fillers) and package sizes can differ. Compare the “Active ingredient” box on both packages, and ask a pharmacist if you are not sure.
- Has Dextromethorphan, phenylephrine and triprolidine been recalled?
- No recall linked to these products appears in the FDA enforcement reports we use.
Drug Facts label
Every over-the-counter medicine must carry a “Drug Facts” box in the same order, set by FDA rules. Below is the label of one product for each common strength and form, quoted word for word. Your own package can differ (for example, children’s products have other directions): always follow the label on your package.
Triponel · Llorens Pharmaceuticals International Division
Dextromethorphan hydrobromide 15 mg/5 mL · Phenylephrine hydrochloride 5 mg/5 mL · Triprolidine hydrochloride 1.25 mg/5 mL, liquid (oral)
Active ingredient (in each 5 mL)
Dextromethorphan HBr 15 mg Phenylephrine HCl 5 mg Triprolidine HCl 1.25 mg
Purpose
Cough Suppressant Nasal Decongestant Antihistamine
Uses
helps to control the reflex that causes coughing temporarily relieves nasal congestion due to common cold, hay fever, or other upper respiratory allergies (allergic, rhinitis) temporarily relieves these symptomes due to hay fever or ther upper respiratory allergies runny nose itchy, watery eyes sneexing itching of the nose or throat
Warnings
Do not use
if you are taking a monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if you r prescirption drug contains an MAOI, ask a doctor or pharmacist before using this product.
Ask a doctor before use if
you have heart disease high blood pressure thyroid disease diabetes difficulty in urination due to enlargement of prostate gland a cough with too much phlegm (mucus) a persistent or chronic cough as occurs with smoking, asthma, chronic bronchitis, or emphysema
Ask a doctor before use if
you are taking sedatives, tranquilizers or drugs for depression or MAOI drugs.
When using this product
do not exceed recommended dose excitability may occur, especially in children drowsiness may occur avoid alcoholic beverages alcohol, sedatives and tranquilizers may increase drowsiness be careful when driving a motor vehicle or operating machinery
Stop use and ask a doctor if
nervousness dizziness, or sleeplessness occurs cough lasts for more than 7 days, comes back, or occurs with a beer, rash, or headache that lasts. These could be signs of a serious condition.
If pregnant or breast-feeding
ask a health professional before use.
Keep out of reach of children
In case of overdose, get medical help or contact a Poison Control Center right away.
Directions
Direcations: Do not exceed more than 4 doses in any 24-hour period or as directed by a doctor.
| Age | Dose |
| Adults and children 12 years of age and over | Take 2 teaspoonfuls (10 mL) every 6 hours |
| Children 6 to under 12 years of age | Take 1 teaspoonful (5 mL) every 6 hours |
| Children under 6 | Ask a docotor |
Inactive ingredients
artificial flavor, citric acid, glycerin, methylparaben, propylene glycol, propylparaben, purified water, sodium citrate, and sucralose.
Questions?
1-866-595-5598
— FDA label of Triponel, Llorens Pharmaceuticals International Division, effective December 31, 2025. See the official label on DailyMed →
This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.
Same medicine, other brands
Each group lists the products that have exactly the same active ingredients, in the same amount and form, as registered with the FDA (NDC Directory). A store brand in the same group has the same medicine as the name brand; inactive ingredients, flavors and package sizes can differ. Each product links to its own official label.
Dextromethorphan hydrobromide 20 mg/5 mL · Phenylephrine hydrochloride 10 mg/5 mL · Triprolidine hydrochloride 2.5 mg/5 mL · syrup (oral) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Histex-Dm | Allegis Pharmaceuticals, LLC | — |
Dextromethorphan hydrobromide 15 mg/5 mL · Phenylephrine hydrochloride 5 mg/5 mL · Triprolidine hydrochloride 1.25 mg/5 mL · liquid (oral) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Triponel | Llorens Pharmaceuticals International Division | DailyMed |
What pharmacies pay (NADAC)
The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.
This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.
| Strength and form | Generic or brand | Pharmacies pay |
|---|---|---|
| dextromethorphan hydrobromide 20 mg/5 mL · phenylephrine hydrochloride 10 mg/5 mL · triprolidine hydrochloride 2.5 mg/5 mL syrup | Generic | $0.0760 per mL |
NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.
Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →
Companies that sell this medicine
The company named on the package (maker or distributor), as listed in the FDA NDC Directory, with its number of over-the-counter products of this medicine.
- Allegis Pharmaceuticals, LLC1 product
- Llorens Pharmaceuticals International Division1 product
Recalls
No recall linked to these products (by their NDC code or label) appears in the FDA enforcement reports.
Sources
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- FDA rule for the Drug Facts label (21 CFR 201.66)
Only medicines marketed under FDA rules for nonprescription drugs (an FDA monograph or an FDA approval) are listed. Homeopathic products are not listed: the FDA does not evaluate them for safety or effectiveness.