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Over-the-counter medicine · no prescription needed

Chlorpheniramine and pseudoephedrine

Purpose on the label: Antihistamine Nasal decongestant

Cough, cold and flu

Official FDA data, not advice

The label text is quoted exactly as the company filed it with the U.S. Food and Drug Administration (FDA), with a link to the official copy. The list of brands comes from the FDA NDC Directory.

This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.

If someone may have taken too much, call Poison Help: 1‑800‑222‑1222. In an emergency, call 911.

Quick answers

What is Chlorpheniramine and pseudoephedrine used for?
The Drug Facts label of LoHist-D (Larken Laboratories, Inc.) lists these uses: temporarily relieves these symptoms due to hay fever (allergic rhinitis): runny nose sneezing itching of the nose or throat itchy, watery eyes temporarily relieves nasal congestion due to the common cold, hay fever or other upper respiratory allergies. temporarily restores freer breathing through the nose.
Do I need a prescription for Chlorpheniramine and pseudoephedrine?
No. The products on this page are sold without a prescription (over the counter).
Is a store brand the same as the name brand?
Products listed together below have the same active ingredients, in the same amount and the same form, as registered with the FDA. Inactive ingredients (such as colors, flavors and fillers) and package sizes can differ. Compare the “Active ingredient” box on both packages, and ask a pharmacist if you are not sure.
Has Chlorpheniramine and pseudoephedrine been recalled?
No recall linked to these products appears in the FDA enforcement reports we use.

Drug Facts label

Every over-the-counter medicine must carry a “Drug Facts” box in the same order, set by FDA rules. Below is the label of one product for each common strength and form, quoted word for word. Your own package can differ (for example, children’s products have other directions): always follow the label on your package.

LoHist-D · Larken Laboratories, Inc.

Chlorpheniramine maleate 2 mg/5 mL · Pseudoephedrine hydrochloride 30 mg/5 mL, liquid (oral)

Active ingredient (In each 5 mL teaspoonful)

Chlorpheniramine Maleate, USP 2 mg Pseudoephedrine HCl, USP 30 mg

Purpose

Chlorpheniramine Maleate Antihistamine Pseudoephedrine HCl Nasal decongestant

Uses

temporarily relieves these symptoms due to hay fever (allergic rhinitis): runny nose sneezing itching of the nose or throat itchy, watery eyes temporarily relieves nasal congestion due to the common cold, hay fever or other upper respiratory allergies. temporarily restores freer breathing through the nose

Warnings

Do not use

to sedate a child or make a child sleepy if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this drug. Ask a Doctor before use if you have heart disease high blood pressure thyroid disease diabetes glaucoma trouble urinating due to an enlarged prostate gland a breathing problem such as emphysema or chronic bronchitis

Ask a doctor or pharmacist before use if

you are. taking any other nasal decongestant or stimulant taking sedatives or tranquilizers

When using this product

Do not exceed recommended dosage. marked drowsiness may occur avoid alcoholic beverages alcohol, sedatives, and tranquilizers may increase drowsiness be careful when driving a motor vehicle or operating machinery excitability may occur, especially in children

Stop use and ask a doctor if

nervousness, dizziness, or sleeplessness occur. symptoms do not improve within 7 days or are accompanied by fever. If pregnant or breast feeding ask a health professional before use. Keep out of the reach of children In case of overdose, get medical help or contact a Poison Control Center immediately.

Directions

Do not exceed 4 doses in a 24-hour period

Age Dose
Adults and children over 12 years of age2 teaspoonfuls (10 mL) every 4 to 6 hours
Children 6 to under 12 years of age1 teaspoonful (5 mL) every 4 to 6 hours
Children under 6 years of ageAsk your doctor

Inactive ingredients

grape flavoring, methylparaben, polyethylene glycol, propylparaben, purified water saccharin sodium, and sorbitol

Questions?

Call 1-601-855-7678 weekdays from 9:00 am to 4:00 pm CST or go to http://www.larkenlabs.com .

— FDA label of LoHist-D, Larken Laboratories, Inc., effective July 28, 2026. See the official label on DailyMed →

SudoGest · Major Pharmaceuticals

Chlorpheniramine maleate 4 mg · Pseudoephedrine hydrochloride 60 mg, tablet (oral)

Active ingredient (in each tablet)

Chlorpheniramine maleate 4 mg Pseudoephedrine HCl 60 mg

Purpose

Antihistamine Nasal decongestant

Uses

temporarily relieves these symptoms due to hay fever (allergic rhinitis) or other upper respiratory allergies: runny nose sneezing itchy, watery eyes nasal congestion itching of the nose or throat temporarily relieves these symptoms due to the common cold: runny nose sneezing sinus congestion and pressure

Warnings

Do not use

if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.

Ask a doctor before use if

you have diabetes heart disease high blood pressure thyroid disease glaucoma difficulty in urination due to enlargement of the prostate gland a breathing problem such as emphysema or chronic bronchitis

Ask a doctor or pharmacist before use if

you are taking sedatives or tranquilizers.

When using this product

do not exceed recommended dosage excitability may occur, especially in children drowsiness may occur alcohol, sedatives, and tranquilizers may increase drowsiness avoid alcoholic beverages use caution when driving a motor vehicle or operating machinery

Stop use and ask a doctor if

nervousness, dizziness, or sleeplessness occur symptoms do not improve within 7 days or occur with a fever

If pregnant or breast-feeding

ask a health professional before use.

Keep out of reach of children

In case of overdose, get medical help or contact a Poison Control Center right away.

Directions

do not take more than directed adults and children 12 years and over: take 1 tablet every 4 to 6 hours. Do not take more than 4 tablets in 24 hours. children under 12 years: do not use

Inactive ingredients

colloidal silicon dioxide, croscarmellose sodium, lactose anhydrous, magnesium stearate, microcrystalline cellulose, stearic acid

Questions?

1-800-426-9391

— FDA label of SudoGest, Major Pharmaceuticals, effective April 1, 2026. See the official label on DailyMed →

This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.

Same medicine, other brands

Each group lists the products that have exactly the same active ingredients, in the same amount and form, as registered with the FDA (NDC Directory). A store brand in the same group has the same medicine as the name brand; inactive ingredients, flavors and package sizes can differ. Each product links to its own official label.

Chlorpheniramine maleate 2 mg/5 mL · Pseudoephedrine hydrochloride 30 mg/5 mL · liquid (oral) · 2 products

Drug Facts for this strength and form ↑

Chlorpheniramine maleate 4 mg · Pseudoephedrine hydrochloride 60 mg · tablet (oral) · 2 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Allergy Relief D Walgreen Company —
SudoGest Major Pharmaceuticals DailyMed

What pharmacies pay (NADAC)

The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.

This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.

NADAC per unit for Chlorpheniramine and pseudoephedrine, by strength and form
Strength and formGeneric or brandPharmacies pay
chlorpheniramine maleate 4 mg · pseudoephedrine hydrochloride 60 mg
tablet
Generic $0.0759 per tablet

NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.

Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →

Companies that sell this medicine

The company named on the package (maker or distributor), as listed in the FDA NDC Directory, with its number of over-the-counter products of this medicine.

Recalls

No recall linked to these products (by their NDC code or label) appears in the FDA enforcement reports.

Sources

  1. Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  2. NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  3. Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
  4. FDA rule for the Drug Facts label (21 CFR 201.66)

Only medicines marketed under FDA rules for nonprescription drugs (an FDA monograph or an FDA approval) are listed. Homeopathic products are not listed: the FDA does not evaluate them for safety or effectiveness.

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