Quick answers
- What is LoHist-D?
- LoHist-D is a brand name of Chlorpheniramine and pseudoephedrine and Brompheniramine, dextromethorphan and phenylephrine, an over-the-counter medicine. The FDA NDC Directory lists 3 LoHist-D products in 2 strengths and forms.
- Who makes LoHist-D?
- Larken Laboratories, Inc. lists 3 of the 3 LoHist-D products in the FDA NDC Directory.
- Is there a generic or store brand of LoHist-D?
- Other products of Chlorpheniramine and pseudoephedrine and Brompheniramine, dextromethorphan and phenylephrine are listed with the FDA, but none in exactly the same strength and form as a LoHist-D product.
- What do pharmacies pay for LoHist-D?
- CMS lists a National Average Drug Acquisition Cost (NADAC) for 1 LoHist-D strength and form (see the table below). That is what pharmacies pay to buy it, not what you pay: your price depends on your insurance and your pharmacy.
- Has LoHist-D been recalled?
- No recall linked to LoHist-D products (by their NDC code or label) appears in the FDA enforcement reports we use.
What LoHist-D is
Each LoHist-D product as listed in the FDA NDC Directory, by active ingredient, strength and form, with its official label. “Same medicine, other names” counts the other products with exactly the same active ingredients, strength and form (generic versions, store brands and other brands); inactive ingredients can differ.
Chlorpheniramine and pseudoephedrine · over-the-counter medicine
| Strength and form | Product names | Same medicine, other names | Label |
|---|---|---|---|
| chlorpheniramine maleate 2 mg/5 mL · pseudoephedrine hydrochloride 30 mg/5 mL liquid (oral) | LoHist-D, LoHist D | None listed | DailyMed |
Its page quotes the Drug Facts label and lists every brand and store brand: Chlorpheniramine and pseudoephedrine →
Brompheniramine, dextromethorphan and phenylephrine · over-the-counter medicine
| Strength and form | Product names | Same medicine, other names | Label |
|---|---|---|---|
| brompheniramine maleate 2 mg/5 mL · dextromethorphan hydrobromide 10 mg/5 mL · phenylephrine hydrochloride 5 mg/5 mL liquid (oral) | LoHist DM | None listed | DailyMed |
Its page quotes the Drug Facts label and lists every brand and store brand: Brompheniramine, dextromethorphan and phenylephrine →
FDA approval
LoHist-D products are sold under an FDA over-the-counter monograph: rules that set the allowed active ingredients, strengths and label wording, so these products do not need an individual FDA approval.
What pharmacies pay (NADAC)
The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.
This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.
| Strength and form | Generic or brand | Pharmacies pay |
|---|---|---|
| brompheniramine maleate 2 mg/5 mL · dextromethorphan hydrobromide 10 mg/5 mL · phenylephrine hydrochloride 5 mg/5 mL liquid | Generic: LoHist-D | $0.0741 per mL Generic of the same strength and form: $0.0741 per mL |
NADAC list of November 4, 2026; these prices took effect on September 23, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.
Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →
Companies that list LoHist-D
The company named on the package (holder, repackager or distributor), as listed in the FDA NDC Directory, with its number of LoHist-D products.
- Larken Laboratories, Inc.3 products
Recalls
No recall linked to LoHist-D products (by their NDC code or label) appears in the FDA enforcement reports.
Sources
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- NADAC (National Average Drug Acquisition Cost) 2026 — Centers for Medicare & Medicaid Services (CMS), data.medicaid.gov, list of November 4, 2026, retrieved November 7, 2026
Which names get a brand page: a name the NDC Directory lists for a medicine, held by one company (the FDA application holder, or the company named on most of its products), that is not just a description, and that is not the only product of its medicine.