Quick answers
- What is Adapalene and benzoyl peroxide used for?
- The Drug Facts label of Differin Epiduo (Galderma Laboratories, L.P.) lists these uses: For the treatment of acne.
- Do I need a prescription for Adapalene and benzoyl peroxide?
- No, the products on this page are sold without a prescription. Other products with the same active ingredients need a prescription (often a higher strength or another form): see the prescription page.
- Is a store brand the same as the name brand?
- Products listed together below have the same active ingredients, in the same amount and the same form, as registered with the FDA. Inactive ingredients (such as colors, flavors and fillers) and package sizes can differ. Compare the “Active ingredient” box on both packages, and ask a pharmacist if you are not sure.
- Has Adapalene and benzoyl peroxide been recalled?
- No recall linked to these products appears in the FDA enforcement reports we use.
Also sold by prescription (often at a higher strength or in another form): Adapalene and benzoyl peroxide — prescription medicine
Drug Facts label
Every over-the-counter medicine must carry a “Drug Facts” box in the same order, set by FDA rules. Below is the label of one product for each common strength and form, quoted word for word. Your own package can differ (for example, children’s products have other directions): always follow the label on your package.
Differin Epiduo · Galderma Laboratories, L.P.
Adapalene 0.1% · Benzoyl peroxide 2.5%, gel (topical)
Active ingredient
Drug Facts Active ingredient Adapalene 0.1% (retinoid)* *read consumer information leaflet Benzoyl Peroxide 2.5%
Purpose
Acne treatment Acne treatment
Uses
For the treatment of acne
Warnings
For external use only
Do not use
on damaged skin (cuts, abrasions, eczema, sunburn) if you are allergic to adapalene or any of the ingredients in this product. If you have very sensitive skin If you are sensitive to benzoyl peroxide
Ask a doctor or pharmacist before use if
you use any other acne medications have any other skin or medical conditions
If pregnant or breast-feeding
ask a doctor before use.
When using this product
limit sun exposure, including light from tanning beds, and use sunscreen when going outdoors do not wax to remove hair in areas where the product has been applied avoid contact with hair and dyed fabrics, which may be bleached by this product during the early weeks of use, your acne may appear to worsen before it improves (this is normal) irritation (redness, itching, dryness, burning, peeling or possible swelling) is more likely to occur: in the first four weeks of use if using more than one topical acne medication at a time If irritation occurs, it may be reduced: by using the product less frequently by using moisturizer by using only one topical acne medication at a time it may take up to 3 months of once daily use to see results avoid product contact with eyes, lips, and mouth. If contact occurs, immediately flush the area with water. wash hands after use Stop use and ask doctor if you become pregnant, or are planning to become pregnant, while using the product you have symptoms of an allergic reaction (such as itching, rash, hives, swelling of the lips, eyelids, and shortness of breath) irritation gets worse you see no improvement after 3 months of once daily use
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away.
Directions
Adults and children 12 years of age and older: use once daily clean the skin gently and pat dry before applying the product cover the entire affected area with a thin layer. For example, if your acne is on the face, apply the product to the entire face. applying more than directed will not provide faster or better results, but may worsen skin irritation. if going outside, apply sunscreen after using this product. If irritation or sensitivity develops, stop use of both products and ask a doctor. Children under 12 years of age: do not use Other information store at 20°C to 25°C (68°F to 77°F) protect from freezing protect from light and keep away from heat
Inactive ingredients
acrylamide/sodium acryloyldimethyltaurate copolymer, docusate sodium, edetate disodium, glycerin, isohexadecane, poloxamer 124, polysorbate 80, propylene glycol, purified water, and sorbitan oleate
Questions?
1-866-735-4137
— FDA label of Differin Epiduo, Galderma Laboratories, L.P., effective May 20, 2026. See the official label on DailyMed →
This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.
Same medicine, other brands
Each group lists the products that have exactly the same active ingredients, in the same amount and form, as registered with the FDA (NDC Directory). A store brand in the same group has the same medicine as the name brand; inactive ingredients, flavors and package sizes can differ. Each product links to its own official label.
Adapalene 0.1% · Benzoyl peroxide 2.5% · gel (topical) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Differin Epiduo | Galderma Laboratories, L.P. | DailyMed |
Companies that sell this medicine
The company named on the package (maker or distributor), as listed in the FDA NDC Directory, with its number of over-the-counter products of this medicine.
- Galderma Laboratories, L.P.1 product
Recalls
No recall linked to these products (by their NDC code or label) appears in the FDA enforcement reports.
Next steps
- Find a pharmacy near youA pharmacist can answer questions about this label
- Adapalene and benzoyl peroxide — prescription medicineSide effects, interactions and dosage from the prescription label
- DifferinBrand page: products, maker and price
- Latest FDA drug recallsPrescription and over-the-counter, newest first
- All over-the-counter medicinesSearch by ingredient, brand or Spanish name
Sources
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- FDA rule for the Drug Facts label (21 CFR 201.66)
Only medicines marketed under FDA rules for nonprescription drugs (an FDA monograph or an FDA approval) are listed. Homeopathic products are not listed: the FDA does not evaluate them for safety or effectiveness.