Medical emergency?Emergency? Call 911. Nearest emergency roomsNearest ERs

Brand-name over-the-counter medicine

Differin

Generic names: Adapalene · Adapalene and benzoyl peroxide

FDA application holder: Galderma Labs LP

Official data, not advice

Everything here comes from the U.S. Food and Drug Administration (FDA): the NDC Directory, Drugs@FDA, the official labels and recall reports; pharmacy costs come from the Centers for Medicare & Medicaid Services (CMS). Each fact shows its source and date.

This page is not medical advice. Read the label on your package, and ask a pharmacist if you are not sure a medicine is right for you or your child.

In an emergency, call 911. If someone may have taken too much of a medicine, call Poison Help: 1‑800‑222‑1222.

Quick answers

What is Differin?
Differin is a brand name of Adapalene and Adapalene and benzoyl peroxide, an over-the-counter medicine. The FDA NDC Directory lists 2 Differin products in 2 strengths and forms.
Who makes Differin?
Galderma Labs LP holds the FDA application for Differin (NDA020380, approved May 31, 1996).
Is there a generic or store brand of Differin?
Yes. The FDA NDC Directory lists 38 other products with the same active ingredients, strength and form as a Differin product, 38 of them generic or store brands. Ask your pharmacist whether one is right for you.
Has Differin been recalled?
No recall linked to Differin products (by their NDC code or label) appears in the FDA enforcement reports we use.

What Differin is

Each Differin product as listed in the FDA NDC Directory, by active ingredient, strength and form, with its official label. “Same medicine, other names” counts the other products with exactly the same active ingredients, strength and form (generic versions, store brands and other brands); inactive ingredients can differ.

Adapalene · over-the-counter medicine

Strength and formProduct namesSame medicine, other namesLabel
adapalene 0.1%
gel (topical)
Differin 38 products, 24 companies DailyMed

Its page quotes the Drug Facts label and lists every brand and store brand: Adapalene →

Adapalene and benzoyl peroxide · over-the-counter medicine

Strength and formProduct namesSame medicine, other namesLabel
adapalene 0.1% · benzoyl peroxide 2.5%
gel (topical)
Differin Epiduo None listed DailyMed

Its page quotes the Drug Facts label and lists every brand and store brand: Adapalene and benzoyl peroxide →

FDA approval

  • NDA: New Drug Application: how a new (usually brand-name) medicine is approved.
FDA applications of Differin products (Drugs@FDA)
ApplicationHolderFirst approvedProducts
NDA020380Galderma Labs LPMay 31, 19961
NDA220736Galderma Labs LPMay 22, 20261

Companies that list Differin

The company named on the package (holder, repackager or distributor), as listed in the FDA NDC Directory, with its number of Differin products.

Recalls

No recall linked to Differin products (by their NDC code or label) appears in the FDA enforcement reports.

Sources

  1. NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  2. Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  3. Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  4. Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
  5. NADAC (National Average Drug Acquisition Cost) 2026 — Centers for Medicare & Medicaid Services (CMS), data.medicaid.gov, list of November 4, 2026, retrieved November 7, 2026

Which names get a brand page: a name the NDC Directory lists for a medicine, held by one company (the FDA application holder, or the company named on most of its products), that is not just a description, and that is not the only product of its medicine.

Report an error → · Information for medicine makers