Quick answers
- What is Valproic acid used for?
- The FDA-approved label (Valproic Acid, Remedyrepack Inc., September 3, 2026) says: “Valproic acid oral solution is indicated for: Monotherapy and adjunctive therapy of complex partial seizures; sole and adjunctive therapy of simple and complex absence seizures; adjunctive therapy in patients with multiple seizure types that include absence seizures 1.1 Epilepsy Valproic acid oral solution is indicated as monotherapy and adjunctive therapy in the treatment of patients with complex partial seizures …” This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or change any medicine.
- Does Valproic acid have a boxed warning?
- Yes. The FDA label for Valproic Acid has a boxed warning (“WARNING: LIFE THREATENING ADVERSE REACTIONS”), the FDA’s strongest warning. Read it on the full label and ask your pharmacist.
- Is there a shortage of Valproic acid?
- No current shortage is listed by the FDA for the products of this medicine (FDA data from October 30, 2026).
- Has Valproic acid been recalled?
- No recall linked to the products of this medicine appears in the FDA enforcement reports we use.
- Who makes Valproic acid?
- 19 companies list prescription products of Valproic acid in the FDA NDC Directory, including Aphena Pharma Solutions - Tennessee, LLC, PAI Holdings, LLC dba PAI Pharma and Remedyrepack Inc..
What Valproic acid is used for
Quoted from the “Indications and Usage” section of the FDA-approved label.
Valproic acid oral solution is indicated for: Monotherapy and adjunctive therapy of complex partial seizures; sole and adjunctive therapy of simple and complex absence seizures; adjunctive therapy in patients with multiple seizure types that include absence seizures 1.1 Epilepsy Valproic acid oral solution is indicated as monotherapy and adjunctive therapy in the treatment of patients with complex partial seizures …
— FDA label: Valproic Acid, Remedyrepack Inc., effective September 3, 2026. Read the full label on DailyMed →
The FDA has 22 labels for products of this medicine (different makers and forms); uses can differ between them. Check the label that comes with your own medicine.
This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or change any medicine.
Conditions named on the label
These condition names appear word for word in the label’s “Indications and Usage” text (matched with a reviewed table). Each page lists hospitals whose own websites name the condition.
Related medical specialties
Boxed warning
A boxed warning (“black box”) is the FDA’s strongest warning on a drug label, for serious or life-threatening risks.
This label has a boxed warning. Its heading: WARNING: LIFE THREATENING ADVERSE REACTIONS
. Read it on the full label →
22 of 22 FDA labels for this medicine have a boxed warning.
Forms and how it is given
| Dosage forms | Solution · Capsule, liquid filled · Capsule |
|---|---|
| Route | Oral |
| Prescription products | 30 in the FDA NDC Directory |
What pharmacies pay (NADAC)
The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.
This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.
| Strength and form | Generic or brand | Pharmacies pay |
|---|---|---|
| valproic acid 250 mg capsule | Generic | $0.2422 per capsule |
| valproic acid 250 mg capsule, liquid filled | Generic | $0.2422 per capsule |
| valproic acid 250 mg/5 mL solution | Generic | $0.0335 per mL |
NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.
Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →
Companies that list this medicine
Labelers in the FDA NDC Directory: the company named on the package (maker or distributor), with the number of prescription products.
- Aphena Pharma Solutions - Tennessee, LLC3 products
- PAI Holdings, LLC dba PAI Pharma3 products
- Remedyrepack Inc.3 products
- Bryant Ranch Prepack2 products
- Major Pharmaceuticals2 products
- American Health Packaging2 products
- Chartwell Governmental & Specialty RX, LLC.2 products
- Chartwell RX, LLC2 products
- ANI Pharmaceuticals, Inc.1 product
- Upsher-Smith Laboratories, LLC1 product
- Bionpharma Inc.1 product
- NorthStar Rx LLC1 product
- Xttrium Laboratories, Inc.1 product
- Actavis Pharma, Inc.1 product
- Kesin Pharma Corporation1 product
- Atlantic Biologicals Corp.1 product
- Direct_Rx1 product
- Quagen Pharmaceuticals LLC1 product
- NCS HealthCare of KY, LLC dba Vangard Labs1 product
FDA approval history
- ANDA: Abbreviated New Drug Application: how a generic version is approved.
Generic approvals (7)
- ANDA070868Pharmobedient Cnsltg · July 1, 1986
- ANDA073229Catalent · October 29, 1991
- ANDA073178Ani Pharms · August 25, 1992
- ANDA073484Bionpharma · June 29, 1993
- ANDA075379Pharm Assoc · December 15, 2000
- ANDA075782Chartwell Rx · December 22, 2000
- ANDA090517Quagen · May 28, 2010
Shortage status
The FDA drug shortage list does not show these products.
Recalls
No recall linked to these products (by their NDC code) appears in the FDA enforcement reports.
Official identifiers
| RxCUI (RxNorm) | 1099681, 1099687 |
|---|---|
| SPL set ID of the quoted label | 1edd220d-d151-4177-9a29-9fee36489fb7 |
| FDA labels (SPL) | 22 |
| FDA applications | 7 ANDA |
| Active ingredients (FDA) | VALPROIC ACID |
Sources
- FDA-approved label on DailyMed (National Library of Medicine) — Valproic Acid, Remedyrepack Inc., effective September 3, 2026; via openFDA, FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- Drug shortages (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
openFDA data is provided by the FDA as is; it may be incomplete. Always rely on the label that comes with your medicine. FDA Enforcement Report search →