Quick answers
- What is Propranolol hydrochloride used for?
- The FDA-approved label (Inderal La, ANI Pharmaceuticals, Inc., August 24, 2026) says: “Hypertension Inderal LA is indicated in the management of hypertension. It may be used alone or used in combination with other antihypertensive agents, particularly a thiazide diuretic. Inderal LA is not indicated in the management of hypertensive emergencies. …” This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or change any medicine.
- Does Propranolol hydrochloride have a boxed warning?
- The label we quote has no boxed warning, but 2 of 133 FDA labels for this medicine do. Check the label of your own product.
- Is there a shortage of Propranolol hydrochloride?
- The FDA drug shortage list shows “Current shortage” for a product of this medicine (updated October 15, 2026). Ask your pharmacist about alternatives.
- Has Propranolol hydrochloride been recalled?
- FDA enforcement reports list 2 recalls of products of this medicine; the newest started January 26, 2022 (Class II). A recall usually concerns specific lots, not every product.
- Who makes Propranolol hydrochloride?
- 43 companies list prescription products of Propranolol hydrochloride in the FDA NDC Directory, including Bryant Ranch Prepack, ANI Pharmaceuticals, Inc. and Remedyrepack Inc..
What Propranolol hydrochloride is used for
Quoted from the “Indications and Usage” section of the FDA-approved label.
Hypertension Inderal LA is indicated in the management of hypertension. It may be used alone or used in combination with other antihypertensive agents, particularly a thiazide diuretic. Inderal LA is not indicated in the management of hypertensive emergencies. …
— FDA label: Inderal La, ANI Pharmaceuticals, Inc., effective August 24, 2026. Read the full label on DailyMed →
The FDA has 133 labels for products of this medicine (different makers and forms); uses can differ between them. Check the label that comes with your own medicine.
This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or change any medicine.
Conditions named on the label
These condition names appear word for word in the label’s “Indications and Usage” text (matched with a reviewed table). Each page lists hospitals whose own websites name the condition.
Related medical specialties
Boxed warning
A boxed warning (“black box”) is the FDA’s strongest warning on a drug label, for serious or life-threatening risks.
The label quoted above has no boxed warning.
2 of 133 FDA labels for this medicine have a boxed warning.
Forms and how it is given
| Dosage forms | Tablet · Capsule, extended release · Solution · Injection, solution · Injection |
|---|---|
| Route | Oral · Intravenous |
| Prescription products | 218 in the FDA NDC Directory |
| Brand names | Inderal La, Inderal XL, Hemangeol, Innopran XL |
What pharmacies pay (NADAC)
The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.
This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.
| Strength and form | Generic or brand | Pharmacies pay |
|---|---|---|
| propranolol hydrochloride 10 mg tablet | Generic | $0.0463 per tablet |
| propranolol hydrochloride 120 mg capsule, extended release | Generic | $0.2062 per capsule |
| propranolol hydrochloride 160 mg capsule, extended release | Generic | $0.3088 per capsule |
| propranolol hydrochloride 20 mg tablet | Generic | $0.0495 per tablet |
| propranolol hydrochloride 20 mg/5 mL solution | Generic | $0.0912 per mL |
| propranolol hydrochloride 40 mg tablet | Generic | $0.0767 per tablet |
| propranolol hydrochloride 40 mg/5 mL solution | Generic | $0.1332 per mL |
| propranolol hydrochloride 60 mg capsule, extended release | Generic | $0.1676 per capsule |
| propranolol hydrochloride 60 mg tablet | Generic | $0.1570 per tablet |
| propranolol hydrochloride 80 mg capsule, extended release | Generic | $0.1849 per capsule |
| propranolol hydrochloride 80 mg capsule, extended release | Brand: Inderal XL | $68.59 per capsule |
| propranolol hydrochloride 80 mg capsule, extended release | Brand: InnoPran XL | $68.59 per capsule |
| propranolol hydrochloride 80 mg tablet | Generic | $0.1546 per tablet |
NADAC list of November 4, 2026; these prices took effect between April 22, 2026 and October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.
Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →
Companies that list this medicine
Labelers in the FDA NDC Directory: the company named on the package (maker or distributor), with the number of prescription products.
- Bryant Ranch Prepack40 products
- ANI Pharmaceuticals, Inc.12 products
- Remedyrepack Inc.9 products
- Golden State Medical Supply, Inc.9 products
- Proficient Rx LP8 products
- A-S Medication Solutions8 products
- American Health Packaging8 products
- Preferred Pharmaceuticals Inc.7 products
- Northwind Health Company, LLC6 products
- Ipca Laboratories Limited5 products
- Amici Pharmaceuticals LLC5 products
- Lifestar Pharma LLC5 products
- Asclemed USA, Inc.5 products
- Par Health USA, LLC5 products
- PD-Rx Pharmaceuticals, Inc.5 products
- Amneal Pharmaceuticals NY LLC5 products
- Mylan Pharmaceuticals Inc.5 products
- Aphena Pharma Solutions - Tennessee, LLC5 products
- NuCare Pharmaceuticals, Inc.5 products
- Lannett Company, Inc.4 products
- Breckenridge Pharmaceutical, Inc.4 products
- AvKARE4 products
- Creekwood Pharmaceuticals LLC4 products
- Direct_Rx4 products
- St. Mary's Medical Park Pharmacy4 products
- Actavis Pharma, Inc.4 products
- NCS HealthCare of KY, LLC dba Vangard Labs3 products
- Hikma Pharmaceuticals USA Inc.3 products
- Coupler LLC3 products
- Advanced Rx of Tennessee, LLC3 products
- AvPAK3 products
- Cardinal Health 107, LLC3 products
- Medical Purchasing Solutions, LLC2 products
- Major Pharmaceuticals2 products
- PAI Holdings, LLC dba PAI Pharma2 products
- Atlantic Biologicals Corp.2 products
- Pharmaceutical Associates, Inc.1 product
- Fresenius Kabi USA, LLC1 product
- HF Acquisition Co LLC, DBA HealthFirst1 product
- Henry Schein, Inc.1 product
- ProPharma Distribution1 product
- Pierre Fabre Pharmaceuticals, Inc.1 product
- Eton Pharmaceuticals, Inc.1 product
FDA approval history
- NDA: New Drug Application: how a new (usually brand-name) medicine is approved.
- ANDA: Abbreviated New Drug Application: how a generic version is approved.
| Application | Sponsor | Approved | Later changes approved |
|---|---|---|---|
| NDA018553 INDERAL LA | Ani Pharms | April 19, 1983 | 35, latest November 7, 2023 2023: Manufacturing (CMC) · 2023: Labeling · 2015: Manufacturing (CMC) |
| NDA021438 INNOPRAN XL | Ani Pharms | March 12, 2003 | 9, latest December 22, 2023 2023: Labeling · 2021: Labeling · 2013: Labeling |
| NDA205410 HEMANGEOL | Eton | March 14, 2014 | 5, latest August 28, 2026 2026: Labeling · 2021: Labeling · 2020: Labeling |
Generic approvals (18)
- ANDA070213Mylan · November 19, 1985
- ANDA070221Ph Health · April 14, 1986
- ANDA070177Watson Labs · May 13, 1986
- ANDA070322Innogenix · August 4, 1986
- ANDA070690Hikma · May 15, 1987
- ANDA071972Impax Labs Inc · April 6, 1988
- ANDA071976Impax Labs Inc · April 6, 1988
- ANDA075826Fresenius Kabi USA · August 31, 2001
- ANDA078494Actavis Elizabeth · August 10, 2007
- ANDA077760Hikma Farmaceutica · January 31, 2008
- ANDA078955Ipca Labs Ltd · June 2, 2008
- ANDA078703Adare Pharms Inc · July 15, 2011
- ANDA212026Amta · January 6, 2020
- ANDA216663Mankind Pharma · January 27, 2026
- ANDA219165Pai Holdings · June 10, 2026
- ANDA219460Creekwood Pharms · August 14, 2026
- ANDA070217—
- ANDA070979—
Shortage status
Current shortage · updated October 15, 2026 · first posted October 31, 2023
| Product | Propranolol Hydrochloride, Injection, 1 mg/1 mL (NDC 63323-604-01) |
|---|---|
| Availability | Unavailable |
| Reason given | Delay in shipping of the drug |
| Company | Fresenius Kabi USA, LLC |
Ask your pharmacist whether your product is affected and what the options are.
Recalls
From FDA enforcement reports, matched by the product’s NDC code. A recall usually covers specific lots only: check the lot number on your package and ask your pharmacist. Do not stop a medicine on your own.
-
January 26, 2022 · Class II · Terminated · D-0194-2024
CGMP Deviations: Products were exposed to temperatures outside of the products labeled storage conditions.
Propranolol Hydrochloride Tablets, 20 mg, 100 Tablets per bottle, Rx only, Manufactured by: Amneal Pharmaceuticals Pvt. Ltd., Ahmedabad 382213, India; Distributed by: Amneal Pharmaceuticals LLC, Bridgewater, NJ 08807. ND — CARDINAL HEALTHCARE
-
August 13, 2014 · Class II · Terminated · D-1545-2014
CGMP Deviations: Citations given to API supplier by the Italian Health Agency AIFA for several critical deficiencies which caused a recall of the API lot used to manufacture Propanolo HCl Injection.
PROPRANOLOL HYDROCHLORIDE INJECTION, USP 1 mg/mL, 1 mL Single Dose Vial, Rx only, APP Pharmaceuticals, LLC Schaumburg, IL 60173, NDC 63323-604-01 — Fresenius Kabi USA, LLC
What do the recall classes mean?
Class I: The most serious type: there is a reasonable chance that using the product will cause serious health problems or death.
Class II: Using the product may cause temporary or medically reversible health problems, or the chance of serious problems is remote.
Class III: Using the product is not likely to cause health problems (for example a labeling or packaging issue).
Official identifiers
Sources
- FDA-approved label on DailyMed (National Library of Medicine) — Inderal La, ANI Pharmaceuticals, Inc., effective August 24, 2026; via openFDA, FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- Drug shortages (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
openFDA data is provided by the FDA as is; it may be incomplete. Always rely on the label that comes with your medicine. FDA Enforcement Report search →