Quick answers
- What is Desonide used for?
- The FDA-approved label (Desonide, Proficient Rx LP, May 1, 2025) says: “Desonide Cream and Lotion are low to medium potency corticosteroids indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatoses.” This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or change any medicine.
- Does Desonide have a boxed warning?
- No. None of the 28 FDA labels we found for this medicine has a boxed warning.
- Is there a shortage of Desonide?
- No current shortage is listed by the FDA for the products of this medicine (FDA data from October 30, 2026).
- Has Desonide been recalled?
- No recall linked to the products of this medicine appears in the FDA enforcement reports we use.
- Who makes Desonide?
- 15 companies list prescription products of Desonide in the FDA NDC Directory, including Bryant Ranch Prepack, Sun Pharmaceutical Industries, Inc. and Alembic Pharmaceuticals Inc..
What Desonide is used for
Quoted from the “Indications and Usage” section of the FDA-approved label.
Desonide Cream and Lotion are low to medium potency corticosteroids indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatoses.
— FDA label: Desonide, Proficient Rx LP, effective May 1, 2025. Read the full label on DailyMed →
The FDA has 28 labels for products of this medicine (different makers and forms); uses can differ between them. Check the label that comes with your own medicine.
This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or change any medicine.
Boxed warning
A boxed warning (“black box”) is the FDA’s strongest warning on a drug label, for serious or life-threatening risks.
The label quoted above has no boxed warning.
0 of 28 FDA labels for this medicine have a boxed warning.
Forms and how it is given
| Dosage forms | Cream · Ointment · Lotion · Gel |
|---|---|
| Route | Topical |
| Prescription products | 29 in the FDA NDC Directory |
| Brand names | Tridesilon Cream |
What pharmacies pay (NADAC)
The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.
This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.
| Strength and form | Generic or brand | Pharmacies pay |
|---|---|---|
| desonide 0.05% cream | Generic | $0.2037–$0.2995 per gram 10 packages, lowest to highest |
| desonide 0.05% ointment | Generic | $0.2678–$0.3762 per gram 10 packages, lowest to highest |
| desonide 0.5 mg/mL lotion | Generic | $0.5141–$0.6056 per mL 6 packages, lowest to highest |
NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.
Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →
Companies that list this medicine
Labelers in the FDA NDC Directory: the company named on the package (maker or distributor), with the number of prescription products.
- Bryant Ranch Prepack7 products
- Sun Pharmaceutical Industries, Inc.3 products
- Alembic Pharmaceuticals Inc.3 products
- Alembic Pharmaceuticals Limited3 products
- Advanced Rx of Tennessee, LLC2 products
- NorthStar Rx LLC2 products
- Padagis Israel Pharmaceuticals Ltd1 product
- Encube Ethicals, Inc.1 product
- Viona Pharmaceuticals Inc1 product
- Zydus Lifesciences Limited1 product
- Actavis Pharma, Inc.1 product
- Cosette Pharmaceuticals, Inc.1 product
- Proficient Rx LP1 product
- Encore Dermatology Inc1 product
- Cintex Services, LLC1 product
FDA approval history
- NDA: New Drug Application: how a new (usually brand-name) medicine is approved.
- ANDA: Abbreviated New Drug Application: how a generic version is approved.
| Application | Sponsor | Approved | Later changes approved |
|---|---|---|---|
| NDA017010 DESONIDE | Padagis Us | January 4, 1972 | 16, latest November 2, 2016 2016: Manufacturing (CMC) · 2014: Manufacturing (CMC) · 2000: Manufacturing (CMC) |
| NDA017426 DESONIDE | Padagis Us | November 1, 1974 | 16, latest June 8, 2016 2016: Manufacturing (CMC) · 2000: Manufacturing (CMC) · 1997: Manufacturing (CMC) |
| NDA019048 DESOWEN | Galderma Labs LP | December 14, 1984 | 12, latest March 13, 2013 2013: Manufacturing (CMC) · 1995: Labeling · 1994: Manufacturing (CMC) |
Generic approvals (11)
- ANDA072354Galderma Labs LP · January 24, 1992
- ANDA073548Sun Pharma Canada · June 30, 1992
- ANDA074027Cosette Pharms Nc · September 28, 1992
- ANDA074254Sun Pharma Canada · August 3, 1994
- ANDA202161Taro · October 31, 2014
- ANDA210998Encube Ethicals · January 30, 2019
- ANDA212473Alembic · October 23, 2019
- ANDA210198Cadila · November 20, 2019
- ANDA202470Pharmazone · May 11, 2020
- ANDA213632Alembic · August 24, 2020
- ANDA214396Alembic · December 8, 2022
Shortage status
The FDA drug shortage list does not show these products.
Recalls
No recall linked to these products (by their NDC code) appears in the FDA enforcement reports.
Official identifiers
Sources
- FDA-approved label on DailyMed (National Library of Medicine) — Desonide, Proficient Rx LP, effective May 1, 2025; via openFDA, FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- Drug shortages (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
openFDA data is provided by the FDA as is; it may be incomplete. Always rely on the label that comes with your medicine. FDA Enforcement Report search →