Quick answers
- What is Desflurane used for?
- The FDA-approved label (Suprane, Henry Schein, Inc., July 15, 2026) says: “1. INDICATIONS AND USAGE 1.1 Induction of Anesthesia SUPRANE is indicated as an inhalation agent for induction of anesthesia for inpatient and outpatient surgery in adults. SUPRANE is contraindicated as an inhalation agent for the induction of anesthesia in pediatric patients because of a high incidence of moderate to severe upper airway adverse events. …” This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or change any medicine.
- Does Desflurane have a boxed warning?
- No. None of the 5 FDA labels we found for this medicine has a boxed warning.
- Is there a shortage of Desflurane?
- The FDA drug shortage list shows “To be discontinued” for a product of this medicine (updated July 2, 2026). Ask your pharmacist about alternatives.
- Has Desflurane been recalled?
- FDA enforcement reports list 1 recall of products of this medicine; the newest started October 6, 2020 (Class III). A recall usually concerns specific lots, not every product.
- Who makes Desflurane?
- 4 companies list prescription products of Desflurane in the FDA NDC Directory, including Baxter Healthcare Corporation, Piramal Critical Care Inc and Henry Schein, Inc..
What Desflurane is used for
Quoted from the “Indications and Usage” section of the FDA-approved label.
1. INDICATIONS AND USAGE 1.1 Induction of Anesthesia SUPRANE is indicated as an inhalation agent for induction of anesthesia for inpatient and outpatient surgery in adults. SUPRANE is contraindicated as an inhalation agent for the induction of anesthesia in pediatric patients because of a high incidence of moderate to severe upper airway adverse events. …
— FDA label: Suprane, Henry Schein, Inc., effective July 15, 2026. Read the full label on DailyMed →
The FDA has 5 labels for products of this medicine (different makers and forms); uses can differ between them. Check the label that comes with your own medicine.
This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or change any medicine.
Boxed warning
A boxed warning (“black box”) is the FDA’s strongest warning on a drug label, for serious or life-threatening risks.
The label quoted above has no boxed warning.
0 of 5 FDA labels for this medicine have a boxed warning.
Forms and how it is given
| Dosage forms | Liquid |
|---|---|
| Route | Respiratory (inhalation) |
| Prescription products | 6 in the FDA NDC Directory |
| Brand names | Suprane |
Companies that list this medicine
Labelers in the FDA NDC Directory: the company named on the package (maker or distributor), with the number of prescription products.
- Baxter Healthcare Corporation3 products
- Piramal Critical Care Inc1 product
- Henry Schein, Inc.1 product
- Sandoz Inc1 product
FDA approval history
- NDA: New Drug Application: how a new (usually brand-name) medicine is approved.
- ANDA: Abbreviated New Drug Application: how a generic version is approved.
| Application | Sponsor | Approved | Later changes approved |
|---|---|---|---|
| NDA020118 SUPRANE | Baxter Hlthcare | September 18, 1992 | 19, latest November 1, 2022 2022: Labeling · 2019: Manufacturing (CMC) · 2019: Labeling |
Generic approvals (2)
- ANDA208234Shanghai Hengrui · February 26, 2018
- ANDA090363Piramal Critical · October 5, 2026
Shortage status
To be discontinued · updated July 2, 2026 · first posted July 2, 2026
| Product | Desflurane, Liquid for Inhalation, 240 mL/240 mL (NDC 0781-6172-86) |
|---|---|
| Company | Jiangsu Hengrui Pharmaceuticals Co. (US Agent eVenus Pharmaceutical Laboratories, Inc.) |
Ask your pharmacist whether your product is affected and what the options are.
Recalls
From FDA enforcement reports, matched by the product’s NDC code. A recall usually covers specific lots only: check the lot number on your package and ask your pharmacist. Do not stop a medicine on your own.
-
October 6, 2020 · Class III · Terminated · D-0042-2021
DEFECTIVE CONTAINER: Desflurane Liquid for Inhalation 240 mL may be leaking.
Desflurane, USP Liquid for Inhalation, 240 mL, Rx Only, Manufactured by: Shanghai Hengrui Pharmaceutical Co., Ltd., Shanghai, 200245, China for Sandoz Inc. Princeton, NJ 08540, NDC 0781-6172-22 — eVenus Pharmaceutical Laboratories
What do the recall classes mean?
Class I: The most serious type: there is a reasonable chance that using the product will cause serious health problems or death.
Class II: Using the product may cause temporary or medically reversible health problems, or the chance of serious problems is remote.
Class III: Using the product is not likely to cause health problems (for example a labeling or packaging issue).
Official identifiers
| RxCUI (RxNorm) | 208919, 562366 |
|---|---|
| SPL set ID of the quoted label | a3e4c8e5-bff0-4a8f-8401-e9866c846ee2 |
| FDA labels (SPL) | 5 |
| FDA applications | NDA020118, 2 ANDA |
| Active ingredients (FDA) | DESFLURANE |
Sources
- FDA-approved label on DailyMed (National Library of Medicine) — Suprane, Henry Schein, Inc., effective July 15, 2026; via openFDA, FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- Drug shortages (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
openFDA data is provided by the FDA as is; it may be incomplete. Always rely on the label that comes with your medicine. FDA Enforcement Report search →