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Brand-name prescription medicine

Xylocaine MPF

Generic names: Lidocaine · Lidocaine hydrochloride,epinephrine bitartrate

FDA application holder: Fresenius Kabi USA

Strengths and generic versions Official label

Official data, not advice

Everything here comes from the U.S. Food and Drug Administration (FDA): the NDC Directory, Drugs@FDA, the official labels and recall reports; pharmacy costs come from the Centers for Medicare & Medicaid Services (CMS). Each fact shows its source and date.

This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or switch any medicine, including a switch between a brand and a generic.

In an emergency, call 911. If someone may have taken too much of a medicine, call Poison Help: 1‑800‑222‑1222.

At a glance

7Strengths and forms
30Same medicine, other names
1948FDA approval
5Recalls (FDA reports)

Quick answers

What is Xylocaine MPF?
Xylocaine MPF is a brand name of Lidocaine and Lidocaine hydrochloride,epinephrine bitartrate, a prescription medicine. The FDA NDC Directory lists 15 Xylocaine MPF products in 7 strengths and forms.
Who makes Xylocaine MPF?
Fresenius Kabi USA holds the FDA application for Xylocaine MPF (NDA006488, approved November 19, 1948). 2 other companies (repackagers or distributors) also list Xylocaine MPF products.
Is there a generic or store brand of Xylocaine MPF?
Yes. The FDA NDC Directory lists 30 other products with the same active ingredients, strength and form as a Xylocaine MPF product, 14 of them generic. Ask your pharmacist whether one is right for you.
Has Xylocaine MPF been recalled?
FDA enforcement reports list 5 recalls of Xylocaine MPF products; the newest started July 16, 2026. A recall usually concerns specific lots, not every product.

What Xylocaine MPF is

Each Xylocaine MPF product as listed in the FDA NDC Directory, by active ingredient, strength and form, with its official label. “Same medicine, other names” counts the other products with exactly the same active ingredients, strength and form (generic versions, store brands and other brands); inactive ingredients can differ.

Lidocaine · prescription medicine

Strength and formProduct namesSame medicine, other namesLabel
lidocaine hydrochloride anhydrous 10 mg/mL
injection, solution (epidural, infiltration, intracaudal, perineural)		 Xylocaine Mpf 13 products, 7 companies DailyMed
lidocaine hydrochloride anhydrous 15 mg/mL
injection, solution (epidural, infiltration, intracaudal, perineural)		 Xylocaine MPF None listed DailyMed
lidocaine hydrochloride anhydrous 20 mg/mL
injection, solution (epidural, infiltration, intracaudal, perineural)		 Xylocaine MPF 12 products, 8 companies DailyMed
lidocaine hydrochloride anhydrous 5 mg/mL
injection, solution (infiltration)		 Xylocaine Mpf 1 product, 1 company DailyMed

Its page lists every product and company, the FDA label’s uses and boxed warning, approvals, shortages and recalls: Lidocaine →

Lidocaine hydrochloride,epinephrine bitartrate · prescription medicine

Strength and formProduct namesSame medicine, other namesLabel
epinephrine bitartrate 0.005 mg/mL · lidocaine hydrochloride anhydrous 10 mg/mL
injection, solution (epidural, infiltration, intracaudal, perineural)		 Xylocaine MPF 1 product, 1 company DailyMed
epinephrine bitartrate 0.005 mg/mL · lidocaine hydrochloride anhydrous 15 mg/mL
injection, solution (epidural, infiltration, intracaudal, perineural)		 Xylocaine MPF None listed DailyMed
epinephrine bitartrate 0.005 mg/mL · lidocaine hydrochloride anhydrous 20 mg/mL
injection, solution (epidural, infiltration, intracaudal, perineural)		 Xylocaine MPF 3 products, 2 companies DailyMed

Its page lists every product and company, the FDA label’s uses and boxed warning, approvals, shortages and recalls: Lidocaine hydrochloride,epinephrine bitartrate →

FDA approval

  • NDA: New Drug Application: how a new (usually brand-name) medicine is approved.
FDA applications of Xylocaine MPF products (Drugs@FDA)
ApplicationHolderFirst approvedProducts
NDA006488Fresenius Kabi USANovember 19, 194815

Companies that list Xylocaine MPF

The company named on the package (holder, repackager or distributor), as listed in the FDA NDC Directory, with its number of Xylocaine MPF products.

Recalls

From FDA enforcement reports, matched by the product’s NDC code or label. A recall usually covers specific lots: check the lot number on your package and ask your pharmacist. Do not stop a medicine on your own.

  1. July 16, 2026 · Class II · Ongoing · D-0728-2026

    Presence of Particulate Matter: Hair was found in products

    Xylocaine (lidocaine HCl Injection, USP), 1%, 200 mg per 20 mL (10 mg per mL), 25 Multiple-Dose Vials, 20 mL, Rx only, Sterile, Fresenius Kabi, Lake Zurich, IL 60047 NDC Tray: 63323-485-27; NDC Vial: 63323-485-01 — Fresenius Kabi USA, LLC

  2. July 16, 2026 · Class II · Ongoing · D-0729-2026

    Presence of Particulate Matter: Hair was found in products

    Xylocaine (lidocaine HCl Injection, USP), 1%, 500 mg per 50 mL (10 mg per mL), 25 Multiple-Dose Vials, 50 mL, Rx only, Sterile, Fresenius Kabi, Lake Zurich, IL 60047 NDC Tray: 63323-485-57; NDC Vial: 63323-485-03 — Fresenius Kabi USA, LLC

  3. April 13, 2022 · Class II · Terminated · D-1052-2022

    cGMP deviations: Temperature abuse

    Xylocaine + Epinephrine, multi dose vial 1%, packaged in a) 20 mL, 25-count box (NDC 63323-482-27) b) 50 mL, 25-count box (NDC 63323-482-57), Rx only, MFG: Fresenius Kabi USA LLC — Mckesson Medical-Surgical Inc. Corporate Office

  4. April 13, 2022 · Class II · Terminated · D-1053-2022

    cGMP deviations: Temperature abuse

    Xylocaine + Epinephrine, multi dose vial 2%, 20 mL, 25 count box, Rx only, MFG: Fresenius Kabi USA LLC, NDC 63323-483-27 — Mckesson Medical-Surgical Inc. Corporate Office

  5. June 25, 2021 · Class II · Terminated · D-0651-2021

    Low out of specification results for epinephrine assay.

    Xylocaine-MPF with Epinephrine 1:200,000, (Lidocaine HCl and Epinephrine Injection, USP), 1%, 300 mg/30 mL, (10 mg/mL), 30 mL Single Dose Vial, 25 Vials per Tray, Rx only, Fresenius Kabi USA, LLC, Lake Zurich, IL 60047. — Fresenius Kabi USA LLC

Sources

  1. NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  2. Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  3. Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  4. Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
  5. NADAC (National Average Drug Acquisition Cost) 2026 — Centers for Medicare & Medicaid Services (CMS), data.medicaid.gov, list of November 4, 2026, retrieved November 7, 2026

Which names get a brand page: a name the NDC Directory lists for a medicine, held by one company (the FDA application holder, or the company named on most of its products), that is not just a description, and that is not the only product of its medicine.

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