Quick answers
- What is Tyenne?
- Tyenne is a brand name of Tocilizumab, a prescription medicine. The FDA NDC Directory lists 7 Tyenne products in 4 strengths and forms.
- Who makes Tyenne?
- Fresenius Kabi USA holds the FDA application for Tyenne (BLA761275, approved March 5, 2024).
- Is there a generic or store brand of Tyenne?
- Yes. The FDA NDC Directory lists 6 other products with the same active ingredients, strength and form as a Tyenne product. Ask your pharmacist whether one is right for you.
- What do pharmacies pay for Tyenne?
- CMS lists a National Average Drug Acquisition Cost (NADAC) for 1 Tyenne strength and form (see the table below). That is what pharmacies pay to buy it, not what you pay: your price depends on your insurance and your pharmacy.
- Has Tyenne been recalled?
- FDA enforcement reports list 1 recall of Tyenne products; the newest started August 10, 2026. A recall usually concerns specific lots, not every product.
What Tyenne is
Each Tyenne product as listed in the FDA NDC Directory, by active ingredient, strength and form, with its official label. “Same medicine, other names” counts the other products with exactly the same active ingredients, strength and form (generic versions, store brands and other brands); inactive ingredients can differ.
Tocilizumab · prescription medicine
| Strength and form | Product names | Same medicine, other names | Label |
|---|---|---|---|
| tocilizumab 162 mg/0.9 mL injection, solution (subcutaneous) | Tyenne | 3 products, 2 companies | DailyMed |
| tocilizumab 200 mg/10 mL injection, solution, concentrate (intravenous) | Tyenne | 1 product, 1 company | DailyMed |
| tocilizumab 400 mg/20 mL injection, solution, concentrate (intravenous) | Tyenne | 1 product, 1 company | DailyMed |
| tocilizumab 80 mg/4 mL injection, solution, concentrate (intravenous) | Tyenne | 1 product, 1 company | DailyMed |
Its page lists every product and company, the FDA label’s uses and boxed warning, approvals, shortages and recalls: Tocilizumab →
FDA approval
- BLA: Biologics License Application: how a biologic medicine (made from living cells) is approved.
What pharmacies pay (NADAC)
The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.
This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.
| Strength and form | Generic or brand | Pharmacies pay |
|---|---|---|
| tocilizumab 162 mg/0.9 mL injection, solution | Brand: Tyenne | $821.27–$823.06 per mL 4 packages, lowest to highest |
NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.
Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →
Companies that list Tyenne
The company named on the package (holder, repackager or distributor), as listed in the FDA NDC Directory, with its number of Tyenne products.
- Fresenius Kabi USA, LLC7 products
Recalls
From FDA enforcement reports, matched by the product’s NDC code or label. A recall usually covers specific lots: check the lot number on your package and ask your pharmacist. Do not stop a medicine on your own.
-
August 10, 2026 · Class I · Ongoing · D-0827-2026
Presence of particulate matter:An internal investigation at the firm found the product to contain glass particles.
Tyenne (tocilizumab-aazg) Injection, 400 mg/20 mL (20 mg/mL), 20 mL vial, Rx Only, Manufactured by Fresenius Kabi USA, LLC, Lake Zurich, Illinois, 60047, NDC 65219-594-20. — Fresenius Kabi USA, LLC
Sources
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- NADAC (National Average Drug Acquisition Cost) 2026 — Centers for Medicare & Medicaid Services (CMS), data.medicaid.gov, list of November 4, 2026, retrieved November 7, 2026
Which names get a brand page: a name the NDC Directory lists for a medicine, held by one company (the FDA application holder, or the company named on most of its products), that is not just a description, and that is not the only product of its medicine.