Quick answers
- What is Creon?
- Creon is a brand name of Pancrelipase, a prescription medicine. The FDA NDC Directory lists 10 Creon products in 5 strengths and forms.
- Who makes Creon?
- Abbvie holds the FDA application for Creon (BLA020725, approved April 30, 2009).
- Is there a generic or store brand of Creon?
- Other products of Pancrelipase are listed with the FDA, but none in exactly the same strength and form as a Creon product.
- What do pharmacies pay for Creon?
- CMS lists a National Average Drug Acquisition Cost (NADAC) for 5 Creon strengths and forms (see the table below). That is what pharmacies pay to buy it, not what you pay: your price depends on your insurance and your pharmacy.
- Has Creon been recalled?
- FDA enforcement reports list 2 recalls of Creon products; the newest started March 15, 2021. A recall usually concerns specific lots, not every product.
What Creon is
Each Creon product as listed in the FDA NDC Directory, by active ingredient, strength and form, with its official label. “Same medicine, other names” counts the other products with exactly the same active ingredients, strength and form (generic versions, store brands and other brands); inactive ingredients can differ.
Pancrelipase · prescription medicine
| Strength and form | Product names | Same medicine, other names | Label |
|---|---|---|---|
| pancrelipase amylase 120000 USP units · pancrelipase lipase 24000 USP units · pancrelipase protease 76000 USP units capsule, delayed release pellets (oral) | Creon | None listed | DailyMed |
| pancrelipase amylase 15000 USP units · pancrelipase lipase 3000 USP units · pancrelipase protease 9500 USP units capsule, delayed release (oral) | Creon | None listed | DailyMed |
| pancrelipase amylase 180000 USP units · pancrelipase lipase 36000 USP units · pancrelipase protease 114000 USP units capsule, delayed release pellets (oral) | Creon | None listed | DailyMed |
| pancrelipase amylase 30000 USP units · pancrelipase lipase 6000 USP units · pancrelipase protease 19000 USP units capsule, delayed release pellets (oral) | Creon | None listed | DailyMed |
| pancrelipase amylase 60000 USP units · pancrelipase lipase 12000 USP units · pancrelipase protease 38000 USP units capsule, delayed release pellets (oral) | Creon | None listed | DailyMed |
Its page lists every product and company, the FDA label’s uses and boxed warning, approvals, shortages and recalls: Pancrelipase →
FDA approval
- BLA: Biologics License Application: how a biologic medicine (made from living cells) is approved.
| Application | Holder | First approved | Products |
|---|---|---|---|
| BLA020725 | Abbvie | April 30, 2009 | 10 |
What pharmacies pay (NADAC)
The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.
This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.
| Strength and form | Generic or brand | Pharmacies pay |
|---|---|---|
| pancrelipase amylase 120000 USP units · pancrelipase lipase 24000 USP units · pancrelipase protease 76000 USP units capsule, delayed release pellets | Brand: Creon | $8.34 per capsule |
| pancrelipase amylase 15000 USP units · pancrelipase lipase 3000 USP units · pancrelipase protease 9500 USP units capsule, delayed release | Brand: Creon | $1.78 per capsule |
| pancrelipase amylase 180000 USP units · pancrelipase lipase 36000 USP units · pancrelipase protease 114000 USP units capsule, delayed release pellets | Brand: Creon | $12.67 per capsule |
| pancrelipase amylase 30000 USP units · pancrelipase lipase 6000 USP units · pancrelipase protease 19000 USP units capsule, delayed release pellets | Brand: Creon | $2.10 per capsule |
| pancrelipase amylase 60000 USP units · pancrelipase lipase 12000 USP units · pancrelipase protease 38000 USP units capsule, delayed release pellets | Brand: Creon | $4.21 per capsule |
NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.
Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →
Companies that list Creon
The company named on the package (holder, repackager or distributor), as listed in the FDA NDC Directory, with its number of Creon products.
- AbbVie Inc.10 products
Recalls
From FDA enforcement reports, matched by the product’s NDC code or label. A recall usually covers specific lots: check the lot number on your package and ask your pharmacist. Do not stop a medicine on your own.
-
March 15, 2021 · Class II · Terminated · D-0402-2021
CGMP Deviations: Intermittent exposure to temperature excursion during storage.
Creon (pancrelipase) Delayed-Release Capsules Dose By Lipase Units Lipase 36,000 USP Units Rx only NDC 0032-3016-13 100 Capsules Marketed by: AbbVie Inc. North Chicago, IL 60064, U.S.A. — Cardinal Health Inc.
-
September 15, 2014 · Class II · Terminated · D-1611-2014
Presence of Foreign Tablets/Capsules; Presence of co-mingled LipaCreon 13000.
CREON (pancrelipase) Delayed-Release Capsules, Lipase 24,000 USP Units, 250 Capsule Bottles, Rx Only. Marketed by: AbbVie Inc., North Chicago, IL 60064, Product of Germany. NDC 0032-1224-07. — AbbVie Inc
Sources
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- NADAC (National Average Drug Acquisition Cost) 2026 — Centers for Medicare & Medicaid Services (CMS), data.medicaid.gov, list of November 4, 2026, retrieved November 7, 2026
Which names get a brand page: a name the NDC Directory lists for a medicine, held by one company (the FDA application holder, or the company named on most of its products), that is not just a description, and that is not the only product of its medicine.