Opioid treatment programs (methadone clinics) in Oklahoma
26 treatment centers. Facilities SAMHSA lists as an opioid treatment program (OTP) or as a federally certified opioid treatment program. Certified OTPs are the programs allowed to give methadone for opioid use disorder; many also offer buprenorphine or naltrexone.
City lists
All 26 in Oklahoma
- Hefner Comprehensive Treatment Center(405) 286‑9533Substance use · Oklahoma City · 948 West Hefner Road
- Keetoowah Cherokee Treatment Services(918) 301‑1500Substance use · Detox · Tulsa · 2727 East Admiral Place
- Mission Treatment Centers, Inc.(405) 286‑9533Opioid treatment program · Oklahoma City · 948 West Hefner Road
- Mission Treatment Centers, Inc.(405) 239‑6815Opioid treatment program · Oklahoma City · 1737 Linwood Blvd
- Mission Treatment Centers, Inc.(918) 665‑2501Opioid treatment program · Tulsa · 5550 South Garnett
- Northeastern Health System(918) 931‑3890Substance use · Detox · Tahlequah · 1323 West Keetoowah Street
- Northeastern Health System Addiction Resource Center(918) 931‑3890Opioid treatment program · Tahlequah · 1323 W Keetoowah St
- OKC VAHCS, Substance Treatment and Recovery, OTP(405) 456‑3144Opioid treatment program · Oklahoma City · 921 Northeast 13th St.
- Oklahoma City Comprehensive Treatment(405) 510‑0417Substance use · Oklahoma City · 1737 Linwood Boulevard
- Oklahoma Treatment Services LLC(918) 337‑6007Substance use · Bartlesville · 610 West Hensley Boulevard
- Oklahoma Treatment Services LLC(918) 429‑7950Substance use · McAlester · 721 South George Nigh Expressway, Suite A
- Oklahoma Treatment Services LLC(405) 686‑7828Opioid treatment program · Oklahoma · 5401 SW 29th
- Oklahoma Treatment Services LLC(405) 616‑3366Opioid treatment program · Oklahoma City · 1613 SE 66th St
- Oklahoma Treatment Services LLC(580) 762‑3217Substance use · Ponca City · 827 East Hubbard Road
- Oklahoma Treatment Services LLC(918) 427‑3344Substance use · Roland · 117 E. Ray Fine Blvd.
- Oklahoma Treatment Services LLC(918) 610‑3366Substance use · Detox · Tulsa · 3445 South Sheridan Road East
- Quapaw Counseling Services(918) 542‑1786Substance use · Miami · 58150 East 66 Road
- Rightway Medical OKC South(405) 616‑3366Substance use · Oklahoma City · 1613 SE 66th Street, Suite A
- Southern Oklahoma Treatment Services(580) 565‑6257Opioid treatment program · Anadarko · 505 N 1st Street
- Southern Oklahoma Treatment Services(580) 226‑6503Substance use · Detox · Ardmore · 905 Holiday Drive
- Southern Oklahoma Treatment Services(580) 355‑7500Opioid treatment program · Lawton · 1307 SW Washington Avenue
- Southern Oklahoma Treatment Services(580) 745‑9083Opioid treatment program · Mead · 5912 US Hwy 70
- Southern Oklahoma Treatment Services(580) 745‑9083Substance use · Detox · Mead · 5912 Highway 70 East
- Southern Oklahoma Treatment Services, Ardmore(580) 226‑5003Opioid treatment program · Ardmore · 905 Holiday Dr.
- The Center for Therapeutic Interventions, PLLC(918) 384‑0002Opioid treatment program · Tulsa · 7477 East 46th Place South
- Tulsa Comprehensive Treatment Center(918) 665‑2501Substance use · Tulsa · 5550 South Garnett Road, Suite 200
Common questions
Opioid treatment programs (methadone clinics) in Oklahoma: how many are there?
SAMHSA’s FindTreatment.gov directory lists 26 treatment centers in Oklahoma that match (13% of the 204 listed in the state). Facilities SAMHSA lists as an opioid treatment program (OTP) or as a federally certified opioid treatment program. Certified OTPs are the programs allowed to give methadone for opioid use disorder; many also offer buprenorphine or naltrexone.
Which cities in Oklahoma have the most?
Oklahoma City (7), Tulsa (5), Ardmore (2), Mead (2) and Tahlequah (2).
Source: SAMHSA, FindTreatment.gov (National Directory of Mental Health and Substance Use Treatment Facilities), retrieved 2026-11-11. SAMHSA publishes no separate release date for this live directory. The directory has no quality ratings, and this list is not a ranking or a recommendation. Methodology