Opioid treatment programs (methadone clinics) in Missouri
31 treatment centers. Facilities SAMHSA lists as an opioid treatment program (OTP) or as a federally certified opioid treatment program. Certified OTPs are the programs allowed to give methadone for opioid use disorder; many also offer buprenorphine or naltrexone.
City lists
All 31 in Missouri
- BHG Columbia Treatment Center(573) 449‑8338Substance use · Columbia · 1301 Vandiver Drive, Suite Y
- BHG Joplin Treatment Center(417) 782‑7966Substance use · Joplin · 2919 East 4th Street
- BHG Kansas City Treatment Center(816) 283‑3877Substance use · Kansas City · 2534 Campbell Street, Suite B
- BHG Poplar Bluff Treatment Center(573) 772‑7937Substance use · Detox · Poplar Bluff · 1369 North Westwood Boulevard
- BHG West Plains Treatment Center(417) 257‑1833Substance use · Mental health · Detox · West Plains · 1639 Bruce Smith Parkway
- BHG XLIII, d/b/a BHG Northern Springfield Treatment Center(417) 210‑6025Opioid treatment program · Springfield · 2551 West Kearney St.
- BHG Xxix, LLC(573) 772‑7937Opioid treatment program · Poplar Bluff · 1369 North Westwood Blv.
- BHG Xxviii, LLC(417) 257‑1833Opioid treatment program · West Plains · 1639 Bruce Smith Pkwy
- Cape Girardeau Metro Treatment Center(573) 335‑4333Substance use · Detox · Cape Girardeau · 760 South Kings Highway, Suite F
- Center for Life Solutions, Inc.(314) 731‑0100Opioid treatment program · Hazelwood · 9144 Pershall
- Compass Health(660) 826‑5885Substance use · Mental health · Sedalia · 1700 West Main Street
- Compass Health Network, Inc(660) 826‑5885Opioid treatment program · Sedalia · 1700 W. Main St.
- DRD Management Inc.(816) 283‑3877Opioid treatment program · Kansas City · 2534 Campbell Street, Suite B
- DRD Management, Inc.(573) 449‑8338Opioid treatment program · Columbia · 1301 Vandiver Road, Suite Y
- DRD Management, Inc.(417) 865‑8045Opioid treatment program · Springfield · 404 E. Battlefield
- Metro Treatment of Missouri(314) 423‑7030Opioid treatment program · Breckenridge · 9733 St. Charles Rock Road, Suite 108
- Metro Treatment of Missouri, LP(573) 335‑4333Opioid treatment program · Cape Girardeau · 760 South Kings Highway, Suite F
- Metro Treatment of Missouri, LP(636) 321‑7600Opioid treatment program · St. Charles · 2027 Campus Drive
- Metro Treatment of Missouri, LP.(816) 233‑7300Opioid treatment program · St. Joseph · 3935 Sherman Avenue
- New Season St Charles Treatment Center(636) 321‑7600Substance use · Detox · Saint Charles · 2027 Campus Drive
- ReDiscover(816) 966‑0900Substance use · Detox · Kansas City · 1000 East 24th Street
- ReDiscover(816) 966‑0900Substance use · Mental health · Detox · Kansas City · 5904 Bannister Road · Spanish
- ReDiscover dba Transitions(816) 965‑1157Opioid treatment program · Kansas City · 1000 East 24th Street
- ReDiscover TOP(816) 347‑0349Opioid treatment program · Kansas City · 5904 Bannister Road
- Saint Joseph Metro Treatment Center(816) 233‑7300Substance use · Detox · Saint Joseph · 3935 Sherman Avenue
- Saint Louis Veterans Affairs Medical Center(314) 625‑6056Substance use · Detox · Saint Louis · 915 North Grand Boulevard
- St Louis Metro Treatment Center(314) 423‑7030Substance use · Detox · Saint Louis · 9733 Saint Charles Rock Road
- VA Medical Center(314) 289‑6418Opioid treatment program · St. Louis · 915 North Grand Ave.
- VCPHCS XV, LLC(417) 782‑7966Opioid treatment program · Joplin · 2919 East 4th Street
- West End Clinic(314) 381‑0560Opioid treatment program · St. Louis · 5736 West Florissant Ave.
- Westend Clinic(314) 381‑0560Substance use · Detox · Saint Louis · 5736 West Florissant Avenue
Common questions
Opioid treatment programs (methadone clinics) in Missouri: how many are there?
SAMHSA’s FindTreatment.gov directory lists 31 treatment centers in Missouri that match (8% of the 385 listed in the state). Facilities SAMHSA lists as an opioid treatment program (OTP) or as a federally certified opioid treatment program. Certified OTPs are the programs allowed to give methadone for opioid use disorder; many also offer buprenorphine or naltrexone.
Which cities in Missouri have the most?
Kansas City (6), Saint Louis (3), Cape Girardeau (2), Columbia (2) and Joplin (2).
Source: SAMHSA, FindTreatment.gov (National Directory of Mental Health and Substance Use Treatment Facilities), retrieved 2026-11-11. SAMHSA publishes no separate release date for this live directory. The directory has no quality ratings, and this list is not a ranking or a recommendation. Methodology