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State

Opioid treatment programs (methadone clinics) in Mississippi

9 treatment centers. Facilities SAMHSA lists as an opioid treatment program (OTP) or as a federally certified opioid treatment program. Certified OTPs are the programs allowed to give methadone for opioid use disorder; many also offer buprenorphine or naltrexone.

All 9 in Mississippi

Common questions

Opioid treatment programs (methadone clinics) in Mississippi: how many are there?

SAMHSA’s FindTreatment.gov directory lists 9 treatment centers in Mississippi that match (6% of the 152 listed in the state). Facilities SAMHSA lists as an opioid treatment program (OTP) or as a federally certified opioid treatment program. Certified OTPs are the programs allowed to give methadone for opioid use disorder; many also offer buprenorphine or naltrexone.

Which cities in Mississippi have the most?

Jackson (3), Biloxi (2), Meridian (2) and Walls (2).

Source: SAMHSA, FindTreatment.gov (National Directory of Mental Health and Substance Use Treatment Facilities), retrieved 2026-11-11. SAMHSA publishes no separate release date for this live directory. The directory has no quality ratings, and this list is not a ranking or a recommendation. Methodology