City · South Dakota · Kingsbury County
Pharmacies in De Smet, SD
2 pharmacies. Community/retail pharmacy: 2. 4 more within 25 miles.
- Lewis Family Drug, LLC(605) 854‑9033Community/retail pharmacy · 111 Calumet Ave SW
- Sanford Medical Center(605) 854‑9033Community/retail pharmacy · 111 Calumet Ave SW
Nearby: Pharmacies within 25 miles
- Buchele Drug0.0 mi · Desmet, SD
- Homer's Pharmacy LLC22 mi · Arlington, SD
- Rafferty Robbins Johnson Inc24 mi · Howard, SD
- Sanford Health Network24 mi · Howard, SD
Nearest emergency rooms
- Avera de Smet Memorial Hospital - CAH1.3 mi · De Smet, SD
- Huron Regional Medical Center31 mi · Huron, SD
- Madison Regional Health System35 mi · Madison, SD
Common questions
How many pharmacies are in De Smet, South Dakota?
Our directory lists 2 pharmacies in De Smet: Lewis Family Drug, LLC and Sanford Medical Center.
Where is the nearest emergency room to De Smet?
Hospitals that list emergency services in Medicare data, near De Smet: Avera de Smet Memorial Hospital - CAH, De Smet (1.3 mi), Huron Regional Medical Center, Huron (31 mi) and Madison Regional Health System, Madison (35 mi). In a medical emergency, call 911.
Pharmacies fill prescriptions, and many also give vaccines and answer questions about your medicines. This list comes from the federal NPI Registry, where every pharmacy that bills health insurance must be registered.
Sources: NPI Registry monthly file, NPPES (updated 2026-11-01, retrieved 2026-11-07). Methodology