City · Missouri · Jefferson County
Pharmacies in De Soto, MO
3 pharmacies. Community/retail pharmacy: 2 · Pharmacy: 1.
- De Soto Drug Co Inc(636) 586‑5533Community/retail pharmacy · 100 N Main St
- Wal-Mart Stores East LP(636) 586‑9666Community/retail pharmacy · 12862 State Route 21
- Walgreen Co(636) 586‑8779Pharmacy · 12977 State Route 21
Nearest emergency rooms
- Parkland Health Center - Bonne Terre12 mi · Bonne Terre, MO
- Mercy Hospital Jefferson14 mi · Crystal City, MO
- Washington County Memorial Hospital17 mi · Potosi, MO
Common questions
How many pharmacies are in De Soto, Missouri?
Our directory lists 3 pharmacies in De Soto: De Soto Drug Co Inc, Wal-Mart Stores East LP and Walgreen Co.
Where is the nearest emergency room to De Soto?
Hospitals that list emergency services in Medicare data, near De Soto: Parkland Health Center - Bonne Terre, Bonne Terre (12 mi), Mercy Hospital Jefferson, Crystal City (14 mi) and Washington County Memorial Hospital, Potosi (17 mi). In a medical emergency, call 911.
Pharmacies fill prescriptions, and many also give vaccines and answer questions about your medicines. This list comes from the federal NPI Registry, where every pharmacy that bills health insurance must be registered.
Sources: NPI Registry monthly file, NPPES (updated 2026-11-01, retrieved 2026-11-07). Methodology