Quick answers
- What is Main Street RX?
- Main Street RX is a community/retail pharmacy in East Prairie, Missouri, according to CMS National Plan and Provider Enumeration System (NPPES).
- Where is Main Street RX?
- 117 E Main St, East Prairie, MO 63845, in Mississippi County, Missouri.
- What is the phone number of Main Street RX?
- (573) 649-9229, as listed by CMS National Plan and Provider Enumeration System (NPPES). Call to confirm hours before you go.
What to ask when you call
- Do you have my medicine in stock, and when will it be ready?
- Do you accept my insurance or Medicare/Medicaid plan?
- What are your hours, and is there a drive-through or delivery?
- Which vaccines do you give, and do I need an appointment?
- Can a pharmacist explain my medicines in my language?
A general checklist, not medical advice. For questions about your health or your medicines, ask your doctor or pharmacist.
Other pharmacies nearby
By straight-line distance (not driving distance).
- Rumfelt Drug Inc14 mi · Hickman, KY · Community/retail pharmacy
- Arcare18 mi · Clinton, KY · Community/retail pharmacy
- Medcare Inc19 mi · Arlington, KY · Community/retail pharmacy
- Arcare21 mi · Bardwell, KY · Community/retail pharmacy
- Bardwell Pharmacy LLC21 mi · Bardwell, KY · Community/retail pharmacy
Community health centers nearby
- East Prairie Dental Center6.4 mi · East Prairie, MO · Community health center
- New Madrid Medical Center15 mi · New Madrid, MO · Community health center
- NMCC School Based Health Center16 mi · New Madrid, MO · Community health center
Clinics and urgent care nearby
- Saint Francis Clinic East Prairie0.0 mi · East Prairie, MO · Rural health clinic
- Mercy Hospital Stoddard12 mi · New Madrid, MO · Rural health clinic
- New Madrid Community Care Center12 mi · New Madrid, MO · Rural health clinic
Nearest emergency rooms
Hospitals that list emergency services in Medicare data, by straight-line distance.
- Missouri Delta Medical Center19 mi · Sikeston, MO
- Baptist Memorial Hospital Union City25 mi · Union City, TN
- Volunteer Community Hospital36 mi · Martin, TN
More in East Prairie
Pharmacies in Mississippi County · Pharmacies in Missouri · Find the closest emergency room to where you are →
Details from the official record
| Type | Community/retail pharmacy |
|---|---|
| Address | 117 E Main St, East Prairie, MO 63845 |
| County | Mississippi County |
| State | Missouri |
| Phone | (573) 649‑9229 |
| Name in the official record | MAIN STREET RX |
| National Provider Identifier (NPI) | 1295366797 |
| In the NPI Registry since | February 3, 2020 |
| NPI record last updated | June 16, 2020 |
| Corrections | Report an error or suggest an update → |
Sources
- NPPES Downloadable File (NPI Registry) — CMS National Plan and Provider Enumeration System (NPPES), data updated 2026-11-01, retrieved 2026-11-07
- NPI Registry record 1295366797 — U.S. Department of Health and Human Services
- U.S. Census Bureau ZIP code areas (gazetteer and ZIP-to-county relationship file) — approximate position (center of the ZIP code area) used for distances, and the county