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Over-the-counter medicine · no prescription needed

Tetrahydrozoline and zinc sulfate

Purpose on the label: Redness reliever Astringent

Eye care

Official FDA data, not advice

The label text is quoted exactly as the company filed it with the U.S. Food and Drug Administration (FDA), with a link to the official copy. The list of brands comes from the FDA NDC Directory.

This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.

If someone may have taken too much, call Poison Help: 1‑800‑222‑1222. In an emergency, call 911.

Quick answers

What is Tetrahydrozoline and zinc sulfate used for?
The Drug Facts label of Discount Drug Mart Eye Drops A.C. (Discount Drug Mart) lists these uses: for temporary relief of discomfort and redness of the eye due to minor eye irritation.
Do I need a prescription for Tetrahydrozoline and zinc sulfate?
No. The products on this page are sold without a prescription (over the counter).
Is a store brand the same as the name brand?
Products listed together below have the same active ingredients, in the same amount and the same form, as registered with the FDA. Inactive ingredients (such as colors, flavors and fillers) and package sizes can differ. Compare the “Active ingredient” box on both packages, and ask a pharmacist if you are not sure.
Has Tetrahydrozoline and zinc sulfate been recalled?
FDA enforcement reports list 2 recalls of products on this page; the newest started September 11, 2026. A recall usually concerns specific products or lots, not every brand.

Drug Facts label

Every over-the-counter medicine must carry a “Drug Facts” box in the same order, set by FDA rules. Below is the label of one product for each common strength and form, quoted word for word. Your own package can differ (for example, children’s products have other directions): always follow the label on your package.

Discount Drug Mart Eye Drops A.C. · Discount Drug Mart

Tetrahydrozoline hydrochloride 0.05% · Zinc sulfate 0.25%, solution (ophthalmic)

Active ingredient

Tetrahydrozoline HCl....0.05% Zinc sulfate.....0.25%

Purpose

Tetrahydrozoline HCl......Redness reliever Zinc sulfate......Astringent

Uses

for temporary relief of discomfort and redness of the eye due to minor eye irritation

Warnings

For external use only

Ask a doctor before use if

you have narrow angle glaucoma

When using this product

pupils may become enlarged temporarily to avoid contamination, do not touch tip of container to any surface. Replace cap after using if solution changes color or becomes cloudy, do not use overuse may produce increased redness of the eye remove contact lens before using

Stop use and ask a doctor if

you experience eye pain changes in vision continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours

If pregnant or breast-feeding

ask a health professional before use

Keep out of reach of children

If swallowed, get medical help or contact a Poison Control Center (1-800-222-1222) right away.

Directions

Instill 1 to 2 drops in the affected eye(s) up to 4 times daily.

Other information

store at 15º-30ºC (59º-86ºF)

Inactive ingredients

benzalkonium chloride, boric acid, edetate disodium, purified water, sodium chloride, sodium citrate

— FDA label of Discount Drug Mart Eye Drops A.C., Discount Drug Mart, effective December 30, 2025. See the official label on DailyMed →

Walgreens Eye Drops Seasonal Relief 15mL · Walgreen Co.

Tetrahydrozoline hydrochloride 0.05% · Zinc sulfate 0.25%, solution/ drops (ophthalmic)

Active ingredient

Tetrahydrozoline HCl 0.05% Zinc sulfate 0.25%

Purpose

Redness reliever Astringent

Uses

  • for temporary relief of discomfort and redness of the eye due to minor eye irritations

Warnings

For external use only

Ask a doctor before use if

you have narrow angle glaucoma

When using this product

  • pupils may become enlarged temporarily
  • to avoid contamination, do not touch tip of container to any surface. Replace cap after using.
  • if solution changes color or becomes cloudy, do not use
  • overuse may produce increased redness of the eye
  • remove contact lens before using

Stop use and ask a doctor if

you experience

  • eye pain
  • changes in vision
  • continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours

If pregnant or breast-feeding

ask a health professional before use.

Keep out of reach of children

If swallowed, get medical help or contact a Poison Control Center right away.

Directions

instill 1 to 2 drops in the affected eye(s) up to four times daily

Other information

store at 15°-30°C (59°-86°F)

Inactive ingredients

benzalkonium chloride, boric acid, edetate disodium, purified water, sodium chloride, sodium citrate

Questions?

1-888-527-4276

— FDA label of Walgreens Eye Drops Seasonal Relief 15mL, Walgreen Co., effective December 20, 2023. See the official label on DailyMed →

CVS Astringent Eye · CVS Pharmacy, Inc.

Tetrahydrozoline hydrochloride 50 mg/100 mL · Zinc sulfate 250 mg/100 mL, solution/ drops (ophthalmic)

Active ingredient

​Active ingredients Tetrahydrozoline HCl 0.05% Zinc sulfate 0.25%

Purpose

​Purpose Tetrahydrozoline HCl...Redness Reliever Zinc sulfate...Astringent

Uses

for temporary relief of discomfort and redness of the eye due to minor eye irritations

Warnings

For external use only

Ask a doctor before use if

you have narrow angle glaucoma

When using this product

pupils may become enlarged temporarily to avoid contamination, do not touch tip of container to any surface. Replace cap after using. if solution changes color or becomes cloudy, do not use overuse may produce increased redness of the eye remove contact lens before using

Stop use and ask a doctor if

you experience eye pain changes in vision continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours

If pregnant or breast-feeding

ask a health professional before use.

Keep out of reach of children

If swallowed, get medical help or contact a Poison Control Center right away.

Directions

Instill 1 or 2 drops in the affected eye(s) up to four times daily.

Other information

Store at 15°-30°C (59°-86°F)

Inactive ingredients

benzalkonium chloride, boric acid, edetate disodium, purified water, sodium chloride, and sodium citrate

— FDA label of CVS Astringent Eye, CVS Pharmacy, Inc., effective December 30, 2025. See the official label on DailyMed →

Medics Choice Eye Drops Seasonal Relief · KC Pharmaceuticals, Inc.

Tetrahydrozoline hydrochloride 0.5 mg/mL · Zinc sulfate 2.5 mg/mL, solution/ drops (ophthalmic)

Active ingredient

Tetrahydrozoline HCl 0.05% Zinc sulfate 0.25%

Purpose

Tetrahydrozoline HCl.....Redness reliever Zinc sulfate...............Astringent

Uses

  • for temporary relief of discomfort and redness of the eye due to minor eye irritations

Warnings

For external use only

Ask a doctor before use if

you have narrow angle glaucoma

When using this product

  • pupils may become enlarged temporarily
  • to avoid contamination, do not touch tip of container to any surface. Replace cap after using.
  • if solution changes color or becomes cloudy, do not use
  • overuse may produce increased redness of the eye
  • remove contact lens before using

Stop use and ask a doctor if

you experience

  • eye pain
  • changes in vision
  • continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours

If pregnant or breast-feeding

ask a health professional before use.

Keep out of reach of children

If swallowed, get medical help or contact a Poison Control Center (1-800-222-1222) right away.

Directions

instill 1 to 2 drops in the affected eye(s) up to 4 times daily

Other information

store at 15°-30°C (59°-86°F)

Inactive ingredients

benzalkonium chloride, boric acid, edetate disodium, purified water, sodium chloride, sodium citrate

— FDA label of Medics Choice Eye Drops Seasonal Relief, KC Pharmaceuticals, Inc., effective December 30, 2025. See the official label on DailyMed →

CareOne Itchy Relief Eye Drops 15mL · Retail Business Services, LLC.

Tetrahydrozoline hydrochloride 0.05% · Zinc sulfate 0.25%, liquid (ophthalmic)

Active ingredient

Tetrahydrozoline HCI 0.05% Zinc sulfate 0.25%

Purpose

Redness reliever Astringent

Uses

for temporary relief of discomfort and redness of the eye due to minor eye irritations

Warnings

For external use only

Ask a doctor before use if

you have narrow angle glaucoma

When using this product

pupils may become enlarged temporarily to avoid contamination, do not touch tip of container to any surface. Replace cap after using. if solution changes color or becomes cloudy, do not use overuse may produce increased redness of the eye remove contact lenses before using

Stop use and ask a doctor if

you experience eye pain changes in vision continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours

If pregnant or breast-feeding

ask a health professional before use.

Keep out of reach of children

If swallowed, get medical help or contact a Poison Control Center (1-800-222-1222) right away.

Directions

instill 1 to 2 drops in the affected eye(s) up to 4 times daily

Other information

store at 15°-30°C (59°-86°F)

Inactive ingredients

benzalkonium chloride, boric acid, edetate disodium, purified water, sodium chloride, sodium citrate

— FDA label of CareOne Itchy Relief Eye Drops 15mL, Retail Business Services, LLC., effective December 30, 2025. See the official label on DailyMed →

Visine A.C. Itchy Eye Relief · Kenvue Brands LLC

Tetrahydrozoline hydrochloride 0.5 mg/mL · Zinc sulfate, unspecified form 2.5 mg/mL, solution/ drops (ophthalmic)

Active ingredient

Purpose Tetrahydrozoline HCl 0.05% Redness reliever Zinc sulfate 0.25% Astringent

Purpose

Active ingredients Purpose Tetrahydrozoline HCl 0.05% Redness reliever Zinc sulfate 0.25% Astringent

Uses

for temporary relief of discomfort and redness of the eye due to minor eye irritations

Warnings

For external use only

Ask a doctor before use if

you have narrow angle glaucoma.

When using this product

pupils may become enlarged temporarily overuse may cause more eye redness remove contact lenses before using do not use if this solution changes color or becomes cloudy do not touch tip of container to any surface to avoid contamination replace cap after each use some users may experience a brief tingling sensation

Stop use and ask a doctor if

you feel eye pain changes in vision occur redness or irritation of the eye lasts condition worsens or lasts more than 72 hours

If pregnant or breast-feeding

ask a health professional before use.

Keep out of reach of children

If swallowed, get medical help or contact a Poison Control Center right away.

Directions

put 1 to 2 drops in the affected eye(s) up to 4 times daily children under 6 years of age: ask a doctor children under 2 years of age: do not use

Inactive ingredients

benzalkonium chloride, boric acid, edetate disodium, purified water, sodium chloride, sodium citrate

Questions?

call toll-free 888-734-7648 or 215-273-8755 (collect)

— FDA label of Visine A.C. Itchy Eye Relief, Kenvue Brands LLC, effective November 13, 2024. See the official label on DailyMed →

This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.

Same medicine, other brands

Each group lists the products that have exactly the same active ingredients, in the same amount and form, as registered with the FDA (NDC Directory). A store brand in the same group has the same medicine as the name brand; inactive ingredients, flavors and package sizes can differ. Each product links to its own official label.

Tetrahydrozoline hydrochloride 0.05% · Zinc sulfate 0.25% · solution (ophthalmic) · 8 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Best Choice Eye Drops A.C. Best Choice (Valu Merchandisers Company) DailyMed
Discount Drug Mart Eye Drops A.C. Discount Drug Mart DailyMed
Equaline Eye Drops A.C. United Natural Foods, Inc. DailyMed
GoodSense Eye Drops Irritation Relief Geiss, Destin & Dunn, Inc. DailyMed
HEB A.C. Eye Drops HEB Grocery Company., LP DailyMed
Kroger Eye Drops Seasonal Relief Kroger DailyMed
Signature Care Eye Drops A.C. Better Living Brands LLC DailyMed
Topcare Health Ultra Itch Relief Astringent Eye Drops Topco Associates LLC DailyMed
Tetrahydrozoline hydrochloride 0.05% · Zinc sulfate 0.25% · solution/ drops (ophthalmic) · 3 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Meijer Seasonal Itching and Redness Relief Meijer Distribution, Inc. DailyMed
Quality Choice Eye Drops Irritation Relief Quality Choice DailyMed
Walgreens Eye Drops Seasonal Relief 15mL Walgreen Co. DailyMed
Tetrahydrozoline hydrochloride 50 mg/100 mL · Zinc sulfate 250 mg/100 mL · solution/ drops (ophthalmic) · 2 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
CVS Astringent Eye CVS Pharmacy, Inc. DailyMed
Winco Irritation Relief Eye WinCo Foods, LLC DailyMed
Tetrahydrozoline hydrochloride 0.5 mg/mL · Zinc sulfate 2.5 mg/mL · solution/ drops (ophthalmic) · 1 product

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Medics Choice Eye Drops Seasonal Relief KC Pharmaceuticals, Inc. DailyMed
Tetrahydrozoline hydrochloride 0.05% · Zinc sulfate 0.25% · liquid (ophthalmic) · 1 product

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
CareOne Itchy Relief Eye Drops 15mL Retail Business Services, LLC. DailyMed
Tetrahydrozoline hydrochloride 0.5 mg/mL · Zinc sulfate, unspecified form 2.5 mg/mL · solution/ drops (ophthalmic) · 1 product

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Visine A.C. Itchy Eye Relief Kenvue Brands LLC DailyMed

Companies that sell this medicine

The company named on the package (maker or distributor), as listed in the FDA NDC Directory, with its number of over-the-counter products of this medicine.

  • Better Living Brands LLC1 product
  • HEB Grocery Company., LP1 product
  • Topco Associates LLC1 product
  • United Natural Foods, Inc.1 product
  • Discount Drug Mart1 product
  • KC Pharmaceuticals, Inc.1 product
  • Kroger1 product
  • Geiss, Destin & Dunn, Inc.1 product
  • Walgreen Co.1 product
  • CVS Pharmacy, Inc.1 product
  • Quality Choice1 product
  • WinCo Foods, LLC1 product
  • Retail Business Services, LLC.1 product
  • Meijer Distribution, Inc.1 product
  • Best Choice (Valu Merchandisers Company)1 product
  • Kenvue Brands LLC1 product

Recalls

From FDA enforcement reports, matched by the product’s NDC code or label. A recall usually covers specific products or lots: check the name and lot number on your package.

  1. September 11, 2026 · Class II · Ongoing · D-0003-2027

    Lack of Assurance of Sterility

    Sterile EYE DROPS AC (tetrahydrozoline HCl 0.05%, zinc sulfate 0.25%), 0.5 fl. oz. (15 mL) bottles; a) Equaline, DISTRIBUTED BY: UNFI, PROVIDENCE, RI 02908 UPC 0 41163 25114 4; b) Good Sense Sterile Eye Drops, Distribute — K.C. Pharmaceuticals, Inc.

  2. March 3, 2026 · Class II · Ongoing · D-0409-2026

    Lack of Assurance of Sterility

    Sterile EYE DROPS AC (tetrahydrozoline HCl 0.05%, zinc sulfate 0.25%), 0.5 fl. oz. (15 mL) bottles; a) Best Choice, PROUDLY DISTRIBUTED BY: VALU MERCHANDISERS, CO., 5000 KANSAS AVE, KANSAS CITY, KS 66106, UPC 0 70038 470 — K.C. Pharmaceuticals, Inc

Next steps

Sources

  1. Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  2. NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  3. Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
  4. FDA rule for the Drug Facts label (21 CFR 201.66)

Only medicines marketed under FDA rules for nonprescription drugs (an FDA monograph or an FDA approval) are listed. Homeopathic products are not listed: the FDA does not evaluate them for safety or effectiveness.

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