Quick answers
- What is Propylene glycol used for?
- The Drug Facts label of Systane Complete PF (Alcon Laboratories, Inc.) lists these uses: for the temporary relief of burning and irritation due to dryness of the eye for the temporary relief of discomfort due to minor irritations of the eye or to exposure to wind or sun for use as a protectant against further irritation or to relieve dryness of the eye for use as a lubricant to prevent further irritation or to relieve dryness of the eye.
- Do I need a prescription for Propylene glycol?
- No. The products on this page are sold without a prescription (over the counter).
- Is a store brand the same as the name brand?
- Products listed together below have the same active ingredient, in the same amount and the same form, as registered with the FDA. Inactive ingredients (such as colors, flavors and fillers) and package sizes can differ. Compare the “Active ingredient” box on both packages, and ask a pharmacist if you are not sure.
- Has Propylene glycol been recalled?
- FDA enforcement reports list 2 recalls of products on this page; the newest started December 31, 2025. A recall usually concerns specific products or lots, not every brand.
Drug Facts label
Every over-the-counter medicine must carry a “Drug Facts” box in the same order, set by FDA rules. Below is the label of one product for each common strength and form, quoted word for word. Your own package can differ (for example, children’s products have other directions): always follow the label on your package.
Systane Complete PF · Alcon Laboratories, Inc.
Propylene glycol 0.06 mg/mL, emulsion (ophthalmic)
Active ingredient
Purpose Propylene Glycol 0.06% Lubricant
Purpose
Active Ingredients Purpose Propylene Glycol 0.06% Lubricant
Uses
for the temporary relief of burning and irritation due to dryness of the eye for the temporary relief of discomfort due to minor irritations of the eye or to exposure to wind or sun for use as a protectant against further irritation or to relieve dryness of the eye for use as a lubricant to prevent further irritation or to relieve dryness of the eye
Warnings
For external use only
Do not use
if this product changes color if you are sensitive to any ingredient in this product
When using this product
do not touch tip of container to any surface to avoid contamination replace cap after each use
Stop use and ask a doctor if
you experience any of the following: eye pain changes in vision continued redness or irritation of the eye condition worsens or persists for more than 72 hours
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away.
Directions
shake well before using put 1 or 2 drops in the affected eye(s) as needed see side of carton for directions for use
Other information
store at room temperature
Inactive ingredients
boric acid, dimyristoyl phosphatidylglycerol, hydroxypropyl guar, mineral oil, polyoxyl 40 stearate, sorbitan tristearate, sorbitol and purified water. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.
Questions?
In the U.S. call 1-800-757-9195 www.systane.com alcon.medinfo@alcon.com Directions for Use: Hold the bottle just below the cap and twist the cap to open. BEFORE FIRST USE , hold the bottle upside down and dispense one drop of product to discard. Shake the bottle downward to remove residual product (see picture). Place 1 or 2 drops in the affected eye(s) as needed and blink. After use, shake the bottle downward to remove residual product that may be left on the tip. Replace cap after use. Discard 90 days after opening. TAMPER EVIDENT: For your protection, this bottle has a tamper evident ring around the bottom of the cap. Do not use if this ring is damaged or missing at the time of purchase. 1 Based on a survey of eye care professionals. Data on file.
— FDA label of Systane Complete PF, Alcon Laboratories, Inc., effective November 3, 2025. See the official label on DailyMed →
Systane Pro PF · Alcon Laboratories, Inc.
Propylene glycol 6 mg/mL, emulsion (ophthalmic)
Active ingredient
Purpose Propylene Glycol 0.6% Lubricant
Purpose
Active Ingredients Purpose Propylene Glycol 0.6% Lubricant
Uses
for the temporary relief of burning and irritation due to dryness of the eye for the temporary relief of discomfort due to minor irritations of the eye or to exposure to wind or sun for use as a protectant against further irritation or to relieve dryness of the eye for use as a lubricant to prevent further irritation or to relieve dryness of the eye
Warnings
For external use only
Do not use
if this product changes color if you are sensitive to any ingredient in this product
When using this product
do not touch tip of container to any surface to avoid contamination replace cap after each use
Stop use and ask a doctor if
you experience any of the following: eye pain changes in vision continued redness or irritation of the eye condition worsens or persists for more than 72 hours
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away.
Directions
shake well before using put 1 or 2 drops in the affected eye(s) as needed see side of carton for directions for use Directions for use: Hold the bottle just below the cap and twist the cap to open. BEFORE FIRST USE , hold the bottle upside down and dispense one drop of product to discard. Shake the bottle downward to remove residual product (see picture). Place 1 or 2 drops in the affected eye(s) as needed and blink. After use, shake the bottle downward to remove residual product that may be left on the tip (see picture on side panel). Replace cap after use. Discard 30 days after opening.
Other information
store at room temperature
Inactive ingredients
boric acid, dimyristoyl phosphatidylglycerol, hydroxypropyl guar, mineral oil, polyoxyl 40 stearate, sodium hyaluronate, sorbitan tristearate, sorbitol and purified water. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.
Questions?
In the U.S. call 1-800-757-9195 www.systane.com alcon.medinfo@alcon.com
— FDA label of Systane Pro PF, Alcon Laboratories, Inc., effective August 10, 2026. See the official label on DailyMed →
Instant Hand Sanitizeing Wipe · Shandong Yayun Sanitary Products Co., Ltd.
Propylene glycol 1.2 g, cloth (topical)
Active ingredient (s)
BENZALKONIUM CHLORIDE 1.2g/pcs. Purpose: Antiseptic
Purpose
Antiseptic, Instant Hand Sanitizeing Wipe
Uses
Instant Hand Sanitizeing Wipe to help reduce bacteria that potentially can cause disease. For use when soap and water are not available.
Warnings
For external use only. Flammable. Keep away from heat or flame
Do not use
in children less than 2 months of age on open skin wounds
When using this product
keep out of eyes, ears, and mouth. In case of contact with eyes, rinse eyes thoroughly with water.
Stop use and ask a doctor if
irritation or rash occurs. These may be signs of a serious condition.
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away.
Directions
Wipe the surface of the skin and let it dry naturally. Supervise children under 6 years of age when using this product to avoid swallowing.
Inactive ingredients
WATER SODIUM CITRATE Compound double-stranded quaternary ammonium salt
— FDA label of Instant Hand Sanitizeing Wipe, Shandong Yayun Sanitary Products Co., Ltd., effective November 21, 2024. See the official label on DailyMed →
Baby Wipes · Shandong Yayun Sanitary Products Co., Ltd.
Propylene glycol 1 g, cloth (topical)
Purpose
Antiseptic, Baby Wipes
Uses
Baby Wipes to help reduce bacteria that potentially can cause disease. For use when soap and water are not available.
Warnings
For external use only. Flammable. Keep away from heat or flame
Do not use
on open skin wounds
When using this product
keep out of eyes, ears, and mouth. In case of contact with eyes, rinse eyes thoroughly with water.
Stop use and ask a doctor if
irritation or rash occurs. These may be signs of a serious condition.
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away.
Directions
Wipe the surface of the skin and let it dry naturally Supervise children under 6 years of age when using this product to avoid swallowing.
Inactive ingredients
WATER Aloe Barbadensis Leaf Extract Chamomile Extract Phenoxyethanol DMDM Hydantoin Ethylhexylglycerin Benzalkonium Chloride
— FDA label of Baby Wipes, Shandong Yayun Sanitary Products Co., Ltd., effective November 20, 2024. See the official label on DailyMed →
VISTA MEIBO TEARS Propylene Glycol 0.6% w/v Advanced Dry Eye Relief Lubricating Drops 10 ml · Red Wedding LLC
Propylene glycol 0.6%, liquid (ophthalmic)
Active ingredient
Propylene glycol 0.6%
Purpose
Lubricant
Uses
For the temporary relief of irritation and burning due to dryness of the eye
Warnings
For external use only.
Do not use
if this product changes color or becomes cloudy if seal is broken or punctured
When using this product
do not touch tip of bottle to any surface to avoid contamination replace cap after each use Stop use and consult a physician if you experience any of the following: eye pain changes in vision irritation or redness for longer than 48 hours
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away.
Directions
shake well before using. instill 1 or 2 drops in the affected eye(s) as needed.
Other information
Store at room temperature (15-30 0 C, 59-86 0 F ). Protect from direct sunlight and freezing temperatures.
Inactive ingredients
Hydroxypropyl Guar, Edetate Disodium, Mineral Oil, Sorbitan Tristearate, Polyoxyl 40 Stearate, Boric Acid, Sorbitol Preservative - Stabilized Oxychloro Complex 0.01% w/v, Purified water
— FDA label of VISTA MEIBO TEARS Propylene Glycol 0.6% w/v Advanced Dry Eye Relief Lubricating Drops 10 ml, Red Wedding LLC, effective January 1, 2025. See the official label on DailyMed →
This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.
Same medicine, other brands
Each group lists the products that have exactly the same active ingredient, in the same amount and form, as registered with the FDA (NDC Directory). A store brand in the same group has the same medicine as the name brand; inactive ingredients, flavors and package sizes can differ. Each product links to its own official label.
Propylene glycol 0.06 mg/mL · emulsion (ophthalmic) · 5 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Systane Balance | Alcon Laboratories, Inc. | DailyMed |
| Systane COMPLETE | Alcon Laboratories, Inc. | DailyMed |
| Systane COMPLETE PF | Alcon Laboratories, Inc. | DailyMed |
Propylene glycol 6 mg/mL · emulsion (ophthalmic) · 3 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Splash Pure PF | Laboratorios Sophia, S.A. De C.V. | DailyMed |
| Systane Pro PF | Alcon Laboratories, Inc. | DailyMed |
Propylene glycol 0.6% · emulsion (ophthalmic) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| OneDrop | Laboratorios Sophia, S.A. De C.V. | — |
Propylene glycol 1.2 g · cloth (topical) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Instant Hand Sanitizeing Wipe | Shandong Yayun Sanitary Products Co., Ltd. | DailyMed |
Propylene glycol 1 g · cloth (topical) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Baby Wipes | Shandong Yayun Sanitary Products Co., Ltd. | DailyMed |
Propylene glycol 0.6% · liquid (ophthalmic) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| VISTA MEIBO TEARS Propylene Glycol 0.6% w/v Advanced Dry Eye Relief Lubricating Drops 10 ml | Red Wedding LLC | DailyMed |
Propylene glycol 0.6% · solution/ drops (ophthalmic) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Leader Restorative Formula Lubricant Eye Drops | Cardinal Health | DailyMed |
What pharmacies pay (NADAC)
The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.
This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.
| Strength and form | Generic or brand | Pharmacies pay |
|---|---|---|
| propylene glycol 0.06 mg/mL emulsion | Brand: Systane Balance | $1.00–$1.17 per mL 2 packages, lowest to highest |
| propylene glycol 0.06 mg/mL emulsion | Brand: Systane COMPLETE | $1.00–$1.36 per mL 3 packages, lowest to highest |
| propylene glycol 0.06 mg/mL emulsion | Brand: Systane COMPLETE PF | $1.35 per mL |
| propylene glycol 6 mg/mL emulsion | Brand: Systane Pro PF | $1.35 per mL |
NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.
Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →
Companies that sell this medicine
The company named on the package (maker or distributor), as listed in the FDA NDC Directory, with its number of over-the-counter products of this medicine.
- Alcon Laboratories, Inc.7 products
- Laboratorios Sophia, S.A. De C.V.2 products
- Shandong Yayun Sanitary Products Co., Ltd.2 products
- Red Wedding LLC1 product
- Cardinal Health1 product
Recalls
From FDA enforcement reports, matched by the product’s NDC code or label. A recall usually covers specific products or lots: check the name and lot number on your package.
-
December 31, 2025 · Class II · Ongoing · D-0348-2026
Lack of Assurance of Sterility: Products have not been manufactured in conformance with current good manufacturing practices.
Vista Meibo Tears Propylene Glycol 0.6% w/v Eye Drops Advanced Dry Eye Relief Revitalizing Formula, 10 ml (1/3 fl.oz.), Wizcure Pharmaa PVT. LTD., H-881, Phase 3, RIICO Industrial Area, Bhiwadi-301019, India, Manufacture — Wizcure Pharmaa Private Limited
-
June 29, 2022 · Class II · Terminated · D-1316-2022
CGMP Deviations: products were stored outside the drug label specifications.
Systane Balance, Lubricant Eye Drops, Propylene Glycol 0.6% lubricant, Restorative Formula, Sterile, 10 mL (1/3 FL OZ) bottle per box, Alcon, NDC 0065-1433-02. — Mckesson Medical-Surgical Inc. Corporate Office
Sources
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- FDA rule for the Drug Facts label (21 CFR 201.66)
Only medicines marketed under FDA rules for nonprescription drugs (an FDA monograph or an FDA approval) are listed. Homeopathic products are not listed: the FDA does not evaluate them for safety or effectiveness.