Medical emergency?Emergency? Call 911. Nearest emergency roomsNearest ERs

Over-the-counter medicine · no prescription needed

Pramoxine hydrochloride and zinc oxide

Purpose on the label: Skin Protectant External analgesic

Pain relief on the skin

Official FDA data, not advice

The label text is quoted exactly as the company filed it with the U.S. Food and Drug Administration (FDA), with a link to the official copy. The list of brands comes from the FDA NDC Directory.

This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.

If someone may have taken too much, call Poison Help: 1‑800‑222‑1222. In an emergency, call 911.

Quick answers

What is Pramoxine hydrochloride and zinc oxide used for?
The Drug Facts label of Calahist (Walgreen Company) lists these uses: Dries the oozing and weeping of poison: ivy; oak; sumac; For the temporary relief of pain and itching associated with; minor skin irritations; rashes due to poison ivy, poison oak, or poison sumac; minor burns; sunburn; minor cuts; scrapes; insect bites.
Do I need a prescription for Pramoxine hydrochloride and zinc oxide?
No. The products on this page are sold without a prescription (over the counter).
Is a store brand the same as the name brand?
Products listed together below have the same active ingredients, in the same amount and the same form, as registered with the FDA. Inactive ingredients (such as colors, flavors and fillers) and package sizes can differ. Compare the “Active ingredient” box on both packages, and ask a pharmacist if you are not sure.
Has Pramoxine hydrochloride and zinc oxide been recalled?
No recall linked to these products appears in the FDA enforcement reports we use.

Drug Facts label

Every over-the-counter medicine must carry a “Drug Facts” box in the same order, set by FDA rules. Below is the label of one product for each common strength and form, quoted word for word. Your own package can differ (for example, children’s products have other directions): always follow the label on your package.

Calahist · Walgreen Company

Pramoxine hydrochloride 10 mg/mL · Zinc oxide 80 mg/mL, lotion (topical)

Active ingredient

Calamine 8% Pramoxine HCI 1%

Purpose

Skin protectant External analgesic

Uses

  • Dries the oozing and weeping of poison:
  • ivy
  • oak
  • sumac
  • For the temporary relief of pain and itching associated with
  • minor skin irritations
  • rashes due to poison ivy, poison oak, or poison sumac
  • minor burns
  • sunburn
  • minor cuts
  • scrapes
  • insect bites

Warnings

  • For external use only
  • Use only as directed.

When using this product

do not get into eyes

Stop use and ask a doctor if

condition worsens, or if symptoms persist for more than 7 days or clear up and occur again within a few days

Keep out of reach of children

In case of accidental ingestion, seek professional assistance or contact a Poison Control Center (1-800-222-1222) right away.

Directions

shake well before using

  • cleanse the skin with soap and water
  • let dry before each use
  • apply lotion to the affected area using cotton or soft cloth
adults and children 2 years and olderNot more than 3 to 4 times daily as needed for comfort
children under 2 yearsConsult a doctor before use

Inactive ingredients

SD alcohol 38B 2.5%, camphor, diazolidinyl urea, fragrances, glycerin, hydroxypropyl methylcellulose, methylparaben, polysorbate 80, propylene glycol, propylparaben and purified water

Questions?

1-888-235-2466

— FDA label of Calahist, Walgreen Company, effective October 27, 2023. See the official label on DailyMed →

This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.

Same medicine, other brands

Each group lists the products that have exactly the same active ingredients, in the same amount and form, as registered with the FDA (NDC Directory). A store brand in the same group has the same medicine as the name brand; inactive ingredients, flavors and package sizes can differ. Each product links to its own official label.

Pramoxine hydrochloride 10 mg/mL · Zinc oxide 80 mg/mL · lotion (topical) · 24 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Best Choice Anti-Itch Clear Valu Merchandisers, CO DailyMed
Best Choice Medicated Calamine Valu Merchandisers, CO. DailyMed
Calahist Walgreen Company DailyMed
CVS Calamine Plus CVS Pharmacy DailyMed
CVS Calamine Plus Roll On CVS Pharmacy —
DDM Calaclear Discount Drug Mart DailyMed
DDM Calagesic Discount Drug Mart DailyMed
Foster and Thrive Caldyphen Strategic Sourcing Services, LLC DailyMed
Freskaro Calamine Plus Pharma Nobis, LLC DailyMed
GNP Caldyphen Amerisource Bergen DailyMed
Harris Teetter Calagesic Harris Tetter, LLC. DailyMed
HEB Calaclear H E B DailyMed
HEB Calagesic H E B DailyMed
Humco Calagesic Humco Holding Group, Inc. DailyMed
Humco Calagesic Pharma Nobis, LLC DailyMed
Leader Calamine Plus Cardinal Health, 110 dba Leader DailyMed
Premier Value Calaclear Chain Drug Consortium DailyMed
Publix Calamine Medicated Publix DailyMed
Publix Clear Anti-Itch Publix DailyMed
Quality Choice Anti-Itch Clear Chain Drug Market Association DailyMed
Quality Choice Anti-itch Medicated Chain Drug Marketing Association Inc DailyMed
Sunmark Caldiphen Strategic Sourcing Services DailyMed
Sunmark Caldyphen Clear Strategic Sourcing Services LLC DailyMed
TopCare Calagesic Topco Associates LLC DailyMed

What pharmacies pay (NADAC)

The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.

This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.

NADAC per unit for Pramoxine hydrochloride and zinc oxide, by strength and form
Strength and formGeneric or brandPharmacies pay
pramoxine hydrochloride 10 mg/mL · zinc oxide 80 mg/mL
lotion
Generic $0.0165 per mL

NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.

Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →

Companies that sell this medicine

The company named on the package (maker or distributor), as listed in the FDA NDC Directory, with its number of over-the-counter products of this medicine.

  • Publix2 products
  • Valu Merchandisers, CO2 products
  • Strategic Sourcing Services LLC2 products
  • Pharma Nobis, LLC2 products
  • H E B2 products
  • CVS Pharmacy2 products
  • Discount Drug Mart2 products
  • Amerisource Bergen1 product
  • Chain Drug Marketing Association Inc1 product
  • Harris Tetter, LLC.1 product
  • Topco Associates LLC1 product
  • Humco Holding Group, Inc.1 product
  • Chain Drug Consortium1 product
  • Strategic Sourcing Services1 product
  • Chain Drug Market Association1 product
  • Walgreen Company1 product
  • Cardinal Health, 110 dba Leader1 product

Recalls

No recall linked to these products (by their NDC code or label) appears in the FDA enforcement reports.

Next steps

Sources

  1. Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  2. NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  3. Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
  4. FDA rule for the Drug Facts label (21 CFR 201.66)

Only medicines marketed under FDA rules for nonprescription drugs (an FDA monograph or an FDA approval) are listed. Homeopathic products are not listed: the FDA does not evaluate them for safety or effectiveness.

Report an error → · Information for medicine makers