Quick answers
- What is Phenylephrine and witch hazel used for?
- The Drug Facts label of Drmitsui Medical Haemorrhoid (Yiyangyuan Life Sciences (Hong Kong) Co., Limited) lists these uses: Swith an appropriate cleansing wipe.Gently dry by patting or blotting witha tissue or a soft cloth before applyinggel. When first opening the tube,puncture foil seal with topend of cap..Apply externally to the affectedarea up to 4 times daily, especiallyat night, in the morning or aftereach bowel movement..Childrenunder 12 years of age: ask a doctor..
- Do I need a prescription for Phenylephrine and witch hazel?
- No. The products on this page are sold without a prescription (over the counter).
- Is a store brand the same as the name brand?
- Products listed together below have the same active ingredients, in the same amount and the same form, as registered with the FDA. Inactive ingredients (such as colors, flavors and fillers) and package sizes can differ. Compare the “Active ingredient” box on both packages, and ask a pharmacist if you are not sure.
- Has Phenylephrine and witch hazel been recalled?
- No recall linked to these products appears in the FDA enforcement reports we use.
Drug Facts label
Every over-the-counter medicine must carry a “Drug Facts” box in the same order, set by FDA rules. Below is the label of one product for each common strength and form, quoted word for word. Your own package can differ (for example, children’s products have other directions): always follow the label on your package.
Drmitsui Medical Haemorrhoid · Yiyangyuan Life Sciences (Hong Kong) Co., Limited
Phenylephrine hydrochloride 0.25% · Witch hazel 50%, gel (topical)
Active ingredient
Phenylephrine HCI 0.25% , Witch hazel 50%.
Purpose
ANAL DISTENDING PAIN. MUCOSAL CONGESTION. PROLAPSE OF HAEMORRHOIDS INTERNAL & MIXED HAEMORRHOIDS.
Uses
Swith an appropriate cleansing wipe.Gently dry by patting or blotting witha tissue or a soft cloth before applyinggel. When first opening the tube,puncture foil seal with topend of cap..Apply externally to the affectedarea up to 4 times daily, especiallyat night, in the morning or aftereach bowel movement..Childrenunder 12 years of age: ask a doctor.
Warnings
For external use only. Keep Out of reach of children
Directions
Apply externally to the affectedarea up to 4 times daily, especiallyat night, in the morning or aftereach bowel movement
Inactive ingredients
Carbomer, Glycerol, Hydroxybenzoate ethyl ester, Triethanolamine, Purified water.
— FDA label of Drmitsui Medical Haemorrhoid, Yiyangyuan Life Sciences (Hong Kong) Co., Limited, effective May 10, 2026. See the official label on DailyMed →
Hemorroidal Cooling gel · Pharmacy Value Alliance, LLC
Phenylephrine hydrochloride 0.25% · Witch hazel 0.5%, gel (topical)
Active ingredient
Phenylephrine HCI 0.25% Active Ingredient Witch Hazel 50%
Purpose
Vasoconstrictor Purpose Astringent
Uses
Helps relieve the local itching and discomfort associated with hemorrhoids temporarily relief of irritation and burning temporarily shrinks hemorrhoidal tissue aids in protecting irritated anorectal areas
Warnings
For External Use Only Ask doctor before use if you have heart disease high blood pressure thyroid disease diabetes difficulty urinating due to an enlarged prostate gland Ask doctor before use if you are presently taking a prescription drug for high blood pressure or depression.
When using this product
do not exceed the recommended daily dosage unless directed by a doctor do not put into the rectum by using fingers or any mechanical device or applicator Stop use and ask a doctor bleeding occurs condition worsens or does not improve within 7 days If pregnant or breast feeding Ask a doctor before use Keep out of the reach of children If swallowed get medical help or contact Poison Control Center right away
Directions
Children under 12 years of age; ask a doctor before use Adults: when practical, clean the affected area by patting or blotting with an appropriate cleansing wipe gently dry by patting or blotting with a tissue or soft cloth before applying when first opening tube, remove foil seal apply externally to the affected area up to 4 times daily, especially at night, in the morning or after each bowel movement
Inactive ingredients
Aloe barbadensis gel, benzophenone-4, Acetate disodium, Hydroxyethylcellulose, methylparaben, polysorbate 80, propylene glycol, propylparaben, sodium citrate, Vitamin E, water
Questions?
Call Toll Free 1-888-296-9067
— FDA label of Hemorroidal Cooling gel, Pharmacy Value Alliance, LLC, effective December 20, 2024. See the official label on DailyMed →
Norms Hemorrhoid · Totally Normal Company
Phenylephrine hydrochloride 0.25% · Witch hazel 50%, spray (topical)
Active ingredient
Phenylephrine HCl 0.25%, Witch Hazel 50%
Purpose
Vasoconstrictor, Astringent
Uses
Temporarily reduces swelling associated with hemorrhoidal tissue. Temporary relief of anorectal itching and discomfort associated with hemorrhoids and other anorectal disorders.
Warnings
For external use only.
When using this product
avoid spraying in eyes, contents under pressure. Do not puncture or incinerate. Do not store at temperatures above 120F, do not exceed recommended daily dosage unless directed by a doctor, do not put this product in the rectum by using fingers or any mechanical device or applicator.
Ask a doctor before use if
you have heart disease, high blood pressure, thyroid disease, diabetes, difficulty in urination due to enlargement of the prostate gland, presently taking a prescription for high blood pressure or depression.
Stop use and ask a doctor if
bleeding occurs, condition worsens or does not improve within 7 days. Ask a healthcare or professional before use. If swallowed, seek medical help or contact a Poison Control Center immediately.
Directions
Adults: when practical, cleanse the affected area with mild soap and warm water and pat dry. Spray the rectal area until thoroughly moist. Wipe off excess with a tissue, gently dry by patting or blotting with a tissue or a soft cloth, apply to the affected area up to 4 times daily especially at night in the morning or after each bowel movement. For children under 12 years of age, consult a doctor.
Inactive ingredients
Alcohol, Aloe Barbadensis Leaf Extract, Benzophenone-4, Benzyl Alcohol, Disodium EDTA, Ethylhexylglycerin, Hydroxyethylcellulose, Polysorbate 80, Propylene Glycol, Sodium Citrate, Tocopherol, Tocopheryl Acetate, Water.
— FDA label of Norms Hemorrhoid, Totally Normal Company, effective August 17, 2025. See the official label on DailyMed →
Drs. pharmacy HEMORRHOIDAL COOLING · OL PHARMA TECH, LLC Drs PHARMACY
Phenylephrine hydrochloride 2.5% · Witch hazel 50%, gel (topical)
Active ingredient
Phenylephrine HCI, 0.25% Witch Hazel, 50.0%
Purpose
Vasoconstrictor Astringent
Uses
helps relieve the local itching and discomfort associated with hemorrhoids temporary relief of irritation and burning temporarily shrinks hemorrhoidal tissue aids in protecting irritated anorectal areas
Warnings
For external use only ASK A DOCTOR BEFORE USE IF YOU HAVE heart disease high blood pressure thyroid disease diabetes difficulty in urination due to enlargement of the prostate gland
Ask a doctor or pharmacist before use if
you are presently taking a prescription drug for high blood pressure or depression WHEN USING THIS PRODUCT do not exceed the recommended daily dosage unless directed by a doctor do not put this product into the rectum by using fingers or any mechanical device or applicator STOP USING AND ASK YOUR DOCTOR IF bleeding occurs condition worsens or does not improve within 7 days IF PREGNENT OR BREAST-FEEDING ask a health professional before use. KEEP OUT OF REACH OF CHILDREN If swallowed, get medical help or contact a Poison Control Center right away.
Directions
adults: when practical, cleanse the affected area by patting or blotting with an appropriate cleansing wipe. Gently dry by patting or blotting with a tissue or a soft cloth before applying gel. when first opening the tube, puncture foil seal with top end of cap apply externally to the affected area up to 4 times daily, especially at night, in the morning or after each bowel movement children under 12 years of age: ask a doctor
Inactive ingredients
edetate disodium, hydroxyethyl cellulose, methylparaben, propylene glycol, propylparaben, purified water, sodium citrate, sodium metabisulphite
Questions?
www.drspharmacyusa.com
— FDA label of Drs. pharmacy HEMORRHOIDAL COOLING, OL PHARMA TECH, LLC Drs PHARMACY, effective January 9, 2025. See the official label on DailyMed →
Cooling Gel · NeilMed Pharmaceuticals Inc.
Phenylephrine 0.25% · Witch hazel 50%, gel (topical)
Active ingredient
Drug Facts Active Ingredients Phenylephrine HCl 0.25% Witch Hazel 50%
Purpose
Phenylephrine HCl 0.25% .......................................................................Vasoconstrictor Witch Hazel 50%. ............................................................................................Astringent
Uses
- helps relieve the local itching and discomfort associated with hemorrhoids
- temporarily shrinks hemorrhoidal tissue
- provides temporary relief from irritation and burning
- temporarily provides a cooling coating for relief of anorectal discomforts
Warnings
For external use only
Ask a doctor before use if
you have Heart disease High blood pressure Thyroid disease Diabetes Difficulty in urination due to enlargement of prostate gland unless directed by a doctor
Ask a doctor or pharmacist before use if
you are presently taking a prescription drug for high blood pressure or depression.
When using this product
do not exceed the recommended daily dosage unless directed by a doctor do not put in the rectum by using fi ngers or any mechanical device or applicator in case of bleeding, consult a doctor promptly.
Stop use and ask a doctor if
Bleeding occurs Condition worsens or does not improve within 7 days.
If pregnant or breastfeeding
ask a health professional before use.
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away. (1-800-222-1222)
Directions
Adults: when practical, cleanse the affected area by patting or blotting with an appropriate cleansing wipe Gently dry by patting or blotting with a tissue or a soft cloth before applying cream When fi rst opening the tube, puncture foil seal with top end of cap Apply externally to the affected area up to 4 times daily Children under 12 years of age: ask a doctor
Other information
TAMPER EVIDENT: DO NOT USE IF SEAL ON TUBE IS PUNCTURED OR MISSING.
Inactive ingredients
Aloe Barbadensis Leaf Extract, Edetate Disodium, Hydroxyethyl Cellulose, Methylparaben, Polysorbate 80, Propylene Glycol, Propylparaben, Purifi ed Water, Sodium Citrate, Sulisobenzone, Vitamin E Acetate.
Questions?
1 (877) 477-8633
— FDA label of Cooling Gel, NeilMed Pharmaceuticals Inc., effective February 4, 2026. See the official label on DailyMed →
This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.
Same medicine, other brands
Each group lists the products that have exactly the same active ingredients, in the same amount and form, as registered with the FDA (NDC Directory). A store brand in the same group has the same medicine as the name brand; inactive ingredients, flavors and package sizes can differ. Each product links to its own official label.
Phenylephrine hydrochloride 0.25% · Witch hazel 50% · gel (topical) · 4 products
Phenylephrine hydrochloride 0.25% · Witch hazel 0.5% · gel (topical) · 2 products
Phenylephrine hydrochloride 0.25% · Witch hazel 50% · spray (topical) · 2 products
Phenylephrine hydrochloride 2.5% · Witch hazel 50% · gel (topical) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Drs. pharmacy HEMORRHOIDAL COOLING | OL PHARMA TECH, LLC Drs PHARMACY | DailyMed |
Phenylephrine 0.25% · Witch hazel 50% · gel (topical) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Cooling Gel | NeilMed Pharmaceuticals Inc. | DailyMed |
Companies that sell this medicine
The company named on the package (maker or distributor), as listed in the FDA NDC Directory, with its number of over-the-counter products of this medicine.
- Walgreens2 products
- Trifecta Pharmaceuticals USA LLC1 product
- Pharmacy Value Alliance, LLC1 product
- Yiyangyuan Life Sciences (Hong Kong) Co., Limited1 product
- Beyond Health P.A.1 product
- Totally Normal Company1 product
- OL PHARMA TECH, LLC Drs PHARMACY1 product
- Haleon US Holdings LLC1 product
- NeilMed Pharmaceuticals Inc.1 product
Recalls
No recall linked to these products (by their NDC code or label) appears in the FDA enforcement reports.
Sources
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- FDA rule for the Drug Facts label (21 CFR 201.66)
Only medicines marketed under FDA rules for nonprescription drugs (an FDA monograph or an FDA approval) are listed. Homeopathic products are not listed: the FDA does not evaluate them for safety or effectiveness.