Quick answers
- What is Naphazoline and pheniramine used for?
- The Drug Facts label of Opcon-A (Bausch & Lomb Incorporated) lists these uses: temporarily relieves itching and redness caused by pollen, ragweed, grass, animal hair and dander.
- Do I need a prescription for Naphazoline and pheniramine?
- No. The products on this page are sold without a prescription (over the counter).
- Is a store brand the same as the name brand?
- Products listed together below have the same active ingredients, in the same amount and the same form, as registered with the FDA. Inactive ingredients (such as colors, flavors and fillers) and package sizes can differ. Compare the “Active ingredient” box on both packages, and ask a pharmacist if you are not sure.
- Has Naphazoline and pheniramine been recalled?
- FDA enforcement reports list 1 recall of products on this page; the newest started June 29, 2022. A recall usually concerns specific products or lots, not every brand.
Drug Facts label
Every over-the-counter medicine must carry a “Drug Facts” box in the same order, set by FDA rules. Below is the label of one product for each common strength and form, quoted word for word. Your own package can differ (for example, children’s products have other directions): always follow the label on your package.
Opcon-A · Bausch & Lomb Incorporated
Naphazoline hydrochloride 0.2675 mg/mL · Pheniramine maleate 3.15 mg/mL, solution/ drops (ophthalmic)
Active ingredient
Naphazoline HCl (0.02675%) Pheniramine maleate (0.315%)
Purpose
Redness reliever Antihistamine
Uses
- temporarily relieves itching and redness caused by pollen, ragweed, grass, animal hair and dander
Warnings
For external use only
Do not use
- if you are sensitive to any ingredient in this product
- if solution changes color or becomes cloudy
Ask a doctor before use if
you have
- heart disease
- high blood pressure
- trouble urinating due to an enlarged prostate gland
- narrow angle glaucoma
When using this product
- overuse may cause more eye redness
- pupils may become enlarged temporarily
- do not touch tip of container to any surface to avoid contamination
- you may feel a brief tingling after putting drops in eye
- replace cap after use
- remove contact lenses before using
Stop use and ask a doctor if
you experience
- eye pain
- changes in vision
- redness or irritation of the eye that worsens or lasts more than 72 hours
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away. Accidental oral ingestion in infants and children may lead to coma and marked reduction in body temperature.
Directions
- Adults and children 6 years of age and older: Instill 1 or 2 drops in the affected eye(s) up to 4 times daily.
- Children under 6 years: ask a doctor
Inactive ingredients
benzalkonium chloride, boric acid, edetate disodium, hypromellose, purified water, sodium borate, sodium chloride. Hydrochloric acid may be used to adjust pH.
Questions?
[phone icon] call: 1-800-553-5340 Distributed by: Bausch & Lomb Americas Inc. Bridgewater, NJ 08807 USA
— FDA label of Opcon-A, Bausch & Lomb Incorporated, effective December 14, 2023. See the official label on DailyMed →
Visine Allergy Eye Relief Multi-Action · Kenvue Brands LLC
Naphazoline hydrochloride 0.25 mg/mL · Pheniramine maleate 3 mg/mL, solution/ drops (ophthalmic)
Active ingredient
Purpose Naphazoline HCl 0.025% Redness reliever Pheniramine maleate 0.3% Antihistamine
Purpose
Active ingredients Purpose Naphazoline HCl 0.025% Redness reliever Pheniramine maleate 0.3% Antihistamine
Uses
Temporarily relieves itchy, red eyes due to: pollen ragweed grass animal hair and dander
Warnings
For external use only
Do not use
if you are sensitive to any ingredient in this product.
Ask a doctor before use if
you have heart disease high blood pressure narrow angle glaucoma trouble urinating
When using this product
pupils may become enlarged temporarily causing light sensitivity do not touch tip of container to any surface to avoid contamination replace cap after each use remove contact lenses before using do not use if this solution changes color or becomes cloudy overuse may cause more eye redness some users may experience a brief tingling sensation
Stop use and ask a doctor if
you feel eye pain changes in vision occur redness or irritation of the eye lasts condition worsens or lasts more than 72 hours
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away. Accidental swallowing by infants and children may lead to coma and marked reduction in body temperature.
Directions
adults and children 6 years of age and over: put 1 or 2 drops in the affected eye(s) up to 4 times a day children under 6 years of age: consult a doctor
Inactive ingredients
benzalkonium chloride, boric acid, edetate disodium, purified water, sodium borate, sodium hydroxide and/or hydrochloric acid
Questions?
call toll-free 888-734-7648 or 215-273-8755 (collect)
— FDA label of Visine Allergy Eye Relief Multi-Action, Kenvue Brands LLC, effective November 13, 2024. See the official label on DailyMed →
Naphazoline HCI And Pheniramine Maleate · Altaire Pharmaceuticals Inc.
Naphazoline hydrochloride 0.27 mg/mL · Pheniramine maleate 3.15 mg/mL, solution/ drops (ophthalmic)
Active ingredient
Naphazoline Hydrochloride (0.027%) Pheniramine Maleate (0.315%)
Purpose
Redness Reliever Antihistamine
Uses
temporarily relieves itching and redness caused by pollen, ragweed, grass, animal hair and dander.
Warnings
if you experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours, discontinue use and consult a physician.
Do not use
in children under 6 years of age unless directed by a physician. If this solution changes color or becomes cloudy, do not use. Overuse of this product may produce increased redness of the eye. If you are sensitive to any ingredient in this product, do not use. To avoid contamination, do not touch tip of container to any surface. Replace cap after using.
Do not use
if imprinted seal on cap is torn, broken or missing, or if imprinted seals on top ad bottom flaps are not intact and completely legible.
Ask a doctor before use if
you have heart disease high blood pressure trouble urinating due to enlarged prostrate gland narrow angle glaucoma Remove contact lenses before using.
Stop use and ask a doctor if
you experience: eye pain, changes in vision, redness or irritation of the eye that worsens or persists for more than 72 hours. Overuse of this product may produce increased redness of the eye. Pupils may become enlarged temporarily. You may experience a brief tingling sensation after putting drops in eyes.
Keep out of reach of children
In case of accidental ingestion, seek professional assistance or contact a Poison Control Center immediately. Accidental oral ingestion in infants and children may lead to coma and marked reduction in body temperature.
Directions
Adults and children 6 years of age and older: instill 1 or 2 drops in affected eye(s) up to 4 times daily. Children under 6 years: ask a doctor.
Inactive ingredients
benzalkonium chloride 0.01%, boric acid, edetate disodium 0.1%, hypromellose, purified water, sodium borate, and sodium chloride.
Questions?
Call (631) 722-5988 9am - 5pm EST Monday - Friday
— FDA label of Naphazoline HCI And Pheniramine Maleate, Altaire Pharmaceuticals Inc., effective December 28, 2020. See the official label on DailyMed →
This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.
Same medicine, other brands
Each group lists the products that have exactly the same active ingredients, in the same amount and form, as registered with the FDA (NDC Directory). A store brand in the same group has the same medicine as the name brand; inactive ingredients, flavors and package sizes can differ. Each product links to its own official label.
Naphazoline hydrochloride 0.2675 mg/mL · Pheniramine maleate 3.15 mg/mL · solution/ drops (ophthalmic) · 7 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Eye Allergy Relief | Cvs Pharmacy | — |
| Eye Allergy Relief | Dolgencorp, LLC | DailyMed |
| Eye Allergy Relief | Target Corporation | DailyMed |
| Eye Allergy Relief | Wal-Mart Stores Inc | DailyMed |
| Eye Allergy Relief | Walgreen Company | DailyMed |
| Opcon-A | Bausch & Lomb Incorporated | DailyMed |
Naphazoline hydrochloride 0.25 mg/mL · Pheniramine maleate 3 mg/mL · solution/ drops (ophthalmic) · 3 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Naphcon A | A-S Medication Solutions | DailyMed |
| Naphcon A | Alcon Laboratories, Inc. | DailyMed |
| Visine Allergy Eye Relief Multi-Action | Kenvue Brands LLC | DailyMed |
Naphazoline hydrochloride 0.27 mg/mL · Pheniramine maleate 3.15 mg/mL · solution/ drops (ophthalmic) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Naphazoline HCI And Pheniramine Maleate | Altaire Pharmaceuticals Inc. | DailyMed |
What pharmacies pay (NADAC)
The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.
This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.
| Strength and form | Generic or brand | Pharmacies pay |
|---|---|---|
| naphazoline hydrochloride 0.25 mg/mL · pheniramine maleate 3 mg/mL solution/ drops | Brand: Naphcon A | $0.5576 per mL |
NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.
Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →
Companies that sell this medicine
The company named on the package (maker or distributor), as listed in the FDA NDC Directory, with its number of over-the-counter products of this medicine.
- Bausch & Lomb Incorporated2 products
- Wal-Mart Stores Inc1 product
- Target Corporation1 product
- Cvs Pharmacy1 product
- Kenvue Brands LLC1 product
- Alcon Laboratories, Inc.1 product
- Dolgencorp, LLC1 product
- Altaire Pharmaceuticals Inc.1 product
- Walgreen Company1 product
- A-S Medication Solutions1 product
Recalls
From FDA enforcement reports, matched by the product’s NDC code or label. A recall usually covers specific products or lots: check the name and lot number on your package.
-
June 29, 2022 · Class II · Terminated · D-1313-2022
CGMP Deviations: products were stored outside the drug label specifications.
Naphcon A eye drops, Naphazoline HCl 0.025% and Pheniramine Maleate 0.3%, Redness Reliever and Antihistamine Eye Drops, Sterile, 15 mL (0.5 FL OZ) bottle per box, Alcon, a Novartis company, NDC 0065-0085-15. — Mckesson Medical-Surgical Inc. Corporate Office
Sources
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- FDA rule for the Drug Facts label (21 CFR 201.66)
Only medicines marketed under FDA rules for nonprescription drugs (an FDA monograph or an FDA approval) are listed. Homeopathic products are not listed: the FDA does not evaluate them for safety or effectiveness.