Quick answers
- What is Naloxone used for?
- The Drug Facts label of Narcan (Emergent Devices Inc.) lists these uses: to “revive” someone during an overdose from many prescription pain medications or street drugs such as heroin this medicine can save a life.
- Do I need a prescription for Naloxone?
- No, the products on this page are sold without a prescription. Other products with the same active ingredient need a prescription (often a higher strength or another form): see the prescription page.
- Is a store brand the same as the name brand?
- Products listed together below have the same active ingredient, in the same amount and the same form, as registered with the FDA. Inactive ingredients (such as colors, flavors and fillers) and package sizes can differ. Compare the “Active ingredient” box on both packages, and ask a pharmacist if you are not sure.
- Has Naloxone been recalled?
- No recall linked to these products appears in the FDA enforcement reports we use.
Also sold by prescription (often at a higher strength or in another form): Naloxone hydrochloride — prescription medicine
Drug Facts label
Every over-the-counter medicine must carry a “Drug Facts” box in the same order, set by FDA rules. Below is the label of one product for each common strength and form, quoted word for word. Your own package can differ (for example, children’s products have other directions): always follow the label on your package.
Narcan · Emergent Devices Inc.
Naloxone hydrochloride 4 mg/0.1 mL, spray (nasal)
Active ingredient (in each spray)
Naloxone Hydrochloride 4 mg
Purpose
Emergency treatment of opioid overdose
Uses
to “revive” someone during an overdose from many prescription pain medications or street drugs such as heroin this medicine can save a life
Warnings
When using this product
some people may experience symptoms when they wake up, such as, shaking, sweating, nausea, or feeling angry. This is to be expected.
Directions
NARCAN ® Naloxone HCl Nasal Spray 4 mg
Emergency Treatment of Opioid Overdose Important:
|
Step 1: CHECK if you suspect an overdose:
| |
Step 2: Give 1 st dose in the nose
| |
Step 3: CALL 911
| |
Step 4: WATCH & GIVE
| |
Step 5: STAY
|
For opioid emergencies, call 911. For questions on NARCAN, call 1-844-4NARCAN (1-844-462-7226) or go to www.narcan.com . ©2023 Emergent Devices Inc. EMERGENT® and NARCAN® are registered trademarks of Emergent BioSolutions Inc, or its subsidiaries. Other Information store at room temperature or refrigerated, between 2°C to 25°C (36°F to 77°F) do not freeze avoid excessive heat above 40°C (104°F) protect from light the product is packaged in individually-sealed blisters. Do not use if the blister is open or torn, or if the device appears damaged. Naloxone HCl Nasal Spray 4 mg 1. Check 2. Give 3. Call 4. Watch/Give 5. Stay
Inactive ingredients
benzalkonium chloride, edetate disodium, hydrochloric acid, sodium chloride, water
Questions?
Call 1-844-4NARCAN (1-844-462-7226) or go to www.narcan.com
— FDA label of Narcan, Emergent Devices Inc., effective August 17, 2026. See the official label on DailyMed →
Naloxone Hydrochloride · Sportpharm LLC
Naloxone hydrochloride 4 mg/0.1 mL, spray, metered (nasal)
Active ingredient (in each spray)
Naloxone hydrochloride 4 mg
Purpose
Emergency treatment of opioid overdose
Uses
to “revive” someone during an overdose from many prescription pain medications or street drugs such as heroin this medicine can save a life
Warnings
When using this product
some people may experience symptoms when they wake up, such as, shaking, sweating, nausea, or feeling angry. This is to be expected.
Directions
Step 1: CHECK if you suspect an overdose:
| |
Step 2: GIVE 1 st dose in the nose
| |
Step 3: CALL
| |
Step 4: WATCH & GIVE
| |
Step 5: STAY
|
step 1 step 2 step 3 step 4 step 5
Other information
Store below 77°F (25°C). do not freeze avoid excessive heat above 40°C (104°F) protect from light the product is packaged in individually-sealed blisters. Do not use if the blister is open or torn, or if the device appears damaged.
Inactive ingredients
benzalkonium chloride, edetate disodium, sodium chloride buffered with sodium hydroxide/hydrochloric acid, water
Questions?
1-888-838-2872 between 9 am and 5 pm ET, Monday-Friday. www.tevausa.com/our-products/tevagenerics
— FDA label of Naloxone Hydrochloride, Sportpharm LLC, effective July 2, 2026. See the official label on DailyMed →
RiVive · Harm Reduction Therapeutics, Inc.
Naloxone hydrochloride 3 mg/0.1 mL, spray (nasal)
Active ingredient (in each spray)
Naloxone hydrochloride 3 mg
Purpose
Emergency treatment of opioid overdose
Uses
- to “revive” someone during an overdose from many prescription pain medications or street drugs such as heroin
- this medicine can save a life
Warnings
When using this product
some people may experience symptoms when they wake up, such as shaking, sweating, nausea, or feeling angry. This is to be expected.
Directions
Step 1: CHECK if you suspect an overdose
| |
Step 2: GIVE 1 st dose in the nose
| |
Step 3: CALL 911
| |
Step 4: WATCH & GIVE
| |
Step 5: STAY
|
Step 1 Step 2 Step 3 Step 4 Step 5
Other information
- store at 20ºC to 25ºC (68ºF to 77ºF)
- do not refrigerate
- avoid excessive heat above 40ºC (104ºF)
- do not use if sealed blister package is torn or opened
Inactive ingredients
hydrochloric acid, purified water, sodium chloride, sodium hydroxide, trisodium citrate dihydrate
Questions?
for more information call toll-free (888)-412-7454 or go to www.RiVive.com
— FDA label of RiVive, Harm Reduction Therapeutics, Inc., effective January 13, 2026. See the official label on DailyMed →
This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.
Same medicine, other brands
Each group lists the products that have exactly the same active ingredient, in the same amount and form, as registered with the FDA (NDC Directory). A store brand in the same group has the same medicine as the name brand; inactive ingredients, flavors and package sizes can differ. Each product links to its own official label.
Naloxone hydrochloride 4 mg/0.1 mL · spray (nasal) · 16 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Narcan | Emergent Devices Inc. | DailyMed |
| Narcan | Sportpharm LLC | DailyMed |
| Narcan Naloxone HCL | HF Acquisition Co LLC, DBA HealthFirst | DailyMed |
| Naloxone Hydrochloride | A-S Medication Solutions | DailyMed |
| Naloxone Hydrochloride | Advanced Rx of Tennessee, LLC | DailyMed |
| Naloxone Hydrochloride | Amerisource Bergen | DailyMed |
| Naloxone Hydrochloride | Amneal Pharmaceuticals LLC | DailyMed |
| Naloxone Hydrochloride | Amneal Pharmaceuticals NY LLC | DailyMed |
| Naloxone Hydrochloride | AvKARE | DailyMed |
| Naloxone Hydrochloride | BluePoint Laboratories | DailyMed |
| Naloxone Hydrochloride | Bryant Ranch Prepack | DailyMed |
| Naloxone Hydrochloride | CVS Pharmacy, Inc | DailyMed |
| Naloxone Hydrochloride | HF Acquisition Co LLC, DBA HealthFirst | DailyMed |
| Naloxone Hydrochloride | Padagis Israel Pharmaceuticals Ltd | DailyMed |
| Naloxone Hydrochloride | Strategic Sourcing Services LLC | DailyMed |
| Naloxone Hydrochloride | Walgreen Co. | DailyMed |
Naloxone hydrochloride 4 mg/0.1 mL · spray, metered (nasal) · 4 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Naloxone Hydrochloride | Actavis Pharma, Inc. | DailyMed |
| Naloxone Hydrochloride | Asclemed USA, Inc. | DailyMed |
| Naloxone Hydrochloride | Sportpharm LLC | DailyMed |
| Naloxone Hydrochloride | Teva Pharmaceuticals, Inc. | DailyMed |
Naloxone hydrochloride 3 mg/0.1 mL · spray (nasal) · 1 product
What pharmacies pay (NADAC)
The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.
This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.
| Strength and form | Generic or brand | Pharmacies pay |
|---|---|---|
| naloxone hydrochloride 4 mg/0.1 mL spray | Generic | $16.77 per unit |
| naloxone hydrochloride 4 mg/0.1 mL spray | Brand: Narcan | $16.08 per unit |
| naloxone hydrochloride 4 mg/0.1 mL spray, metered | Generic | $16.77 per unit |
NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.
Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →
Companies that sell this medicine
The company named on the package (maker or distributor), as listed in the FDA NDC Directory, with its number of over-the-counter products of this medicine.
- Sportpharm LLC2 products
- HF Acquisition Co LLC, DBA HealthFirst2 products
- Actavis Pharma, Inc.1 product
- BluePoint Laboratories1 product
- Advanced Rx of Tennessee, LLC1 product
- CVS Pharmacy, Inc1 product
- Amneal Pharmaceuticals NY LLC1 product
- Amneal Pharmaceuticals LLC1 product
- Amerisource Bergen1 product
- Emergent Devices Inc.1 product
- Asclemed USA, Inc.1 product
- Harm Reduction Therapeutics, Inc.1 product
- AvKARE1 product
- Bryant Ranch Prepack1 product
- Padagis Israel Pharmaceuticals Ltd1 product
- A-S Medication Solutions1 product
- Walgreen Co.1 product
- Teva Pharmaceuticals, Inc.1 product
- Strategic Sourcing Services LLC1 product
Recalls
No recall linked to these products (by their NDC code or label) appears in the FDA enforcement reports.
Sources
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- FDA rule for the Drug Facts label (21 CFR 201.66)
Only medicines marketed under FDA rules for nonprescription drugs (an FDA monograph or an FDA approval) are listed. Homeopathic products are not listed: the FDA does not evaluate them for safety or effectiveness.