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Over-the-counter medicine · no prescription needed

Menthol and methyl salicylate

Purpose on the label: Topical Analgesic

Pain relief on the skin

Official FDA data, not advice

The label text is quoted exactly as the company filed it with the U.S. Food and Drug Administration (FDA), with a link to the official copy. The list of brands comes from the FDA NDC Directory.

This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.

If someone may have taken too much, call Poison Help: 1‑800‑222‑1222. In an emergency, call 911.

Quick answers

What is Menthol and methyl salicylate used for?
The Drug Facts label of Arthritis Hot (Chattem, Inc.) lists these uses: temporarily relieves minor pain associated with: arthritis simple backache muscle strains sprains bruises cramps Uses temporarily relieves minor pain associated with: arthritis simple backache muscle strains sprains bruises.
Do I need a prescription for Menthol and methyl salicylate?
No. The products on this page are sold without a prescription (over the counter).
Is a store brand the same as the name brand?
Products listed together below have the same active ingredients, in the same amount and the same form, as registered with the FDA. Inactive ingredients (such as colors, flavors and fillers) and package sizes can differ. Compare the “Active ingredient” box on both packages, and ask a pharmacist if you are not sure.
Has Menthol and methyl salicylate been recalled?
FDA enforcement reports list 2 recalls of products on this page; the newest started April 24, 2025. A recall usually concerns specific products or lots, not every brand.

Drug Facts label

Every over-the-counter medicine must carry a “Drug Facts” box in the same order, set by FDA rules. Below is the label of one product for each common strength and form, quoted word for word. Your own package can differ (for example, children’s products have other directions): always follow the label on your package.

Arthritis Hot · Chattem, Inc.

Menthol 10% · Methyl salicylate 15%, cream (topical)

Active ingredient

Menthol 10% Methyl salicylate 15% Active ingredients Menthol 10% Methyl salicylate 15%

Purpose

Topical analgesic Purpose Topical analgesic

Uses

temporarily relieves minor pain associated with: arthritis simple backache muscle strains sprains bruises cramps Uses temporarily relieves minor pain associated with: arthritis simple backache muscle strains sprains bruises

Warnings

  • For external use only Allergy alert: If prone to allergic reaction from aspirin or salicylates, consult a doctor before use.

When using this product

  • use only as directed. Read and follow all directions and warnings on this label.
  • rare cases of serious burns have been reported with products of this type
  • do not bandage tightly or apply local heat (such as heating pads) or a medicated patch to the area of use
  • avoid contact with eyes and mucous membranes
  • do not apply to wounds or damaged, broken or irritated skin
  • a transient burning sensation may occur upon application but generally disappears in several days
  • if severe burning sensation occurs, discontinue use immediately
  • do not expose the area treated with product to heat or direct sunlight

Stop use and ask a doctor if

condition worsens redness is present Irritation develops symptoms persist for more than 7 days or clear up and occur again within a few days you experience signs of skin injury, such as pain, swelling, or blistering where the product was applied

If pregnant or breast-feeding

ask a health care professional before use.

Keep out of reach of children

If swallowed, get medical help or contact a Poison Control Center right away.

  • Warnings For external use only Allergy alert: if prone to allergic reaction from aspirin or salicylates, consult a doctor before use.

When using this product

  • use only as directed. Read and follow all directions and warnings on this label.
  • rare cases of serious burns have been reported with products of this type
  • do not bandage tightly or apply local heat (such as heating pads) or a medicated patch to the area of use
  • avoid contact with eyes and mucous membranes
  • do not apply to wounds or damaged, broken or irritated skin
  • a transient burning sensation may occur upon application but generally disappears in several days
  • if severe burning sensation occurs, discontinue use immediately
  • do not expose the area treated with product to heat or direct sunlight

Stop use and ask a doctor if

condition worsens redness is present Irritation develops symptoms persist for more than 7 days or clear up and occur again within a few days you experience signs of skin injury, such as pain, swelling, or blistering where the product was applied

If pregnant or breast-feeding

ask a health professional before use.

Keep out of reach of children

If swallowed, get medical help or contact a Poison Control Center right away.

Directions

adults and children over 12 years:

  • apply a thin layer to affected area
  • massage into painful area until thoroughly absorbed into skin
  • repeat as necessary, but no more than 3 to 4 times daily
  • IF MEDICINE COMES IN CONTACT WITH HANDS, WASH WITH SOAP AND WATER children 12 years or younger: ask a doctor Directions adults and children over 12 years:
  • apply a thin layer to affected area
  • massage into painful area until thoroughly absorbed into skin
  • repeat as necessary, but no more than 3 to 4 times daily
  • IF MEDICINE COMES IN CONTACT WITH HANDS, WASH WITH SOAP AND WATER children 12 years or younger: ask a doctor

Inactive ingredients

Carbomer, cetearyl alcohol, cetyl esters, diisapropyl adipate, oleth-3 phosphate, polysorbate 60, stearic acid, triethanolamine, water Arthritis Hot Cream Inactive ingredients Carbomer, cetearyl alcohol, cetyl esters, diisapropyl adipate, oleth-3 phosphate, polysorbate 60, stearic acid, triethanolamine, water

— FDA label of Arthritis Hot, Chattem, Inc., effective January 13, 2025. See the official label on DailyMed →

Eagle Medicated · Borden Company (Private) Limited

Menthol 14.5% · Methyl salicylate 30%, oil (topical)

Active ingredient

Menthol 14.5% Methyl Salicylate 30%

Purpose

Topical Analgesic Topical Analgesic

Uses

temporarily relieves the minor aches and pains of muscle and joint associated with :

  • simple backache
  • strains
  • bruises
  • sprains

Warnings

For external use only

Do not use

  • on woulds or damaged skin
  • with a heating pad

When using this product

  • avoid contact with eyes or mucous membranes
  • do not bandage tightly

Stop use and ask a doctor if

  • condition worsens or symptoms persist for more than 7 days
  • symptoms clear up and occur again within a few days
  • excessive skin irritation occurs Keep this drug out of reach of children To avoid accidental poisoning, if swallowed, get medical help or contact a Poison Control Center right away.

Directions

  • Use only as directed
  • adults and children 2 years and older: apply to affected area not more than 3 to 4 time daily.
  • children under 2 years of age: ask a doctor

Inactive ingredients

Chlorophyll, ethyl alcohol, mineral oil, rose oil

Questions?

Question? 1-800-777-6717 or 1-800-645-0789

— FDA label of Eagle Medicated, Borden Company (Private) Limited, effective April 10, 2025. See the official label on DailyMed →

RockSauce Warming Massage · Implus Footcare, LLC

Menthol 100 mg/mL · Methyl salicylate 200 mg/mL, cream (topical)

Active ingredient

Menthol 10% Methyl Salicylate 20% PURPOSE Topical Analgesic

Purpose

Topical Analgesic

Uses

Provides soothing heat to sore muscles and joints.

Warnings

For external use only.

When using this product

do not take by mouth or place in nostrils, apply to wounds or damaged skin. Use as directed. Ask a health professional before use if you have sensitive skin or are pregnant or breastfeeding, Discontinue use if irritation occurs.

Keep out of reach of children

In case of accidental ingestion, get medical help or call Poison Control Center right away. Not for children 5 years or younger.

Directions

Apply liberally to area of pain and massage until lotion is absorbed into the skin. Repeat 3-4 times daily. Store at 68º to 77ºF (20º to 25ºC)

Inactive ingredients

Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Aloe Barbadensis Leaf Juice, Ammonium Acryloyldimethyltaurate/VP Copolymer, Aminomethyl Propanol, Arnica Montana Flower Extract, Capsaicin, Cetearyl alcohol, Ethylhexylglycerin, Maltodextrin, Phenoxyethanol, Potassium Cetyl Phosphate, Propylene glycol, Tocopheryl Acetate, Water

— FDA label of RockSauce Warming Massage, Implus Footcare, LLC, effective January 29, 2026. See the official label on DailyMed →

Rayo Active Ice · Quimicas Handal de Centroamerica SA de CV

Menthol 100% · Methyl salicylate 100%, cream (topical)

Active ingredient

Mentol, Camphor (synthetic)

Purpose

When applied to chest and throat, temporarily relieves cough due to minor throat and bronchial irritation associated with common cold.

Uses

Directions Adults and children 2 years of age and older: Rub a thick layer well over throat and chest Use 3 to 4 times daily Keep clothes loose about throat and chest to help vapors reach nose and mouth For muscle and joint minor aches apply to affected area no more than 3 to 4 times daily Children under 2 years: do not use.

Warnings

For external use only; avoid contact with eyes Ask a doctor before if you have: sensitive skin

Do not use

by mouth in nostrils on wounds or damaged skin

When using this product

Avoid contact with the ayes or muccus membranes Wash hands after use with cool water Do not microwave

Stop use and ask a doctor if

Cough occurs with too much mucus (phlegm), or if symptoms persist for more than 7 days or clear up and occur again within a few days.

Keep out of reach of children

: If accidentally ingested, get medical help or contact a Poison Control Center immediately.

Directions

Adults and children 2 years of age and older: Rub a thick layer well over throat and chest Use 3 to 4 times daily Keep clothes loose about throat and chest to help vapors reach nose and mouth For muscle and joint minor aches apply to affected area no more than 3 to 4 times daily Children under 2 years: do not use.

Inactive ingredients

T

Questions?

info@quimicashandal.com

— FDA label of Rayo Active Ice, Quimicas Handal de Centroamerica SA de CV, effective January 22, 2026. See the official label on DailyMed →

Numbing · FlexiGo Inc

Menthol 3% · Methyl salicylate 10%, cream (topical)

Active ingredient

OTC-ACTIVE INGREDIENT SECTION

Purpose

OTC-PURPOSE SECTION

Uses

& USAGE SECTION

Warnings

OTC-DO NOT USE SECTION OTC-WHEN USE SECTION OTC-KEEP OUT OF REACH OF CHILDREN SECTION

Directions

DOSAGE&ADMINISTRATION SECTION

Inactive ingredients

SECTION

— FDA label of Numbing, FlexiGo Inc, effective March 13, 2026. See the official label on DailyMed →

Equate Cool and Heat · Wal-Mart Stores Inc

Menthol, unspecified form 10% · Methyl salicylate 30%, cream (topical)

Active ingredient

Menthol 10% Methyl salicylate 30%

Purpose

Menthol - Topical analgesic Methyl salicylate - Topical analgesic

Uses

temporarily relieves minor aches and pains of muscles and joints due to: simple backache arthritis bruises muscle strains muscle sprains

Warnings

For external use only

When using this product

use only as directed do not get into eyes or on mucous membranes do not apply to wounds or damaged skin do not bandage tightly do not use with a heating pad or apply external heat

Stop use and ask a doctor if

skin redness or excessive irritation of the skin occurs condition worsens symptoms persist for more than 7 days or clear up and occur again within a few days

If pregnant or breast-feeding

ask a health professional before use. Keep Out of Reach of Children If swallowed, get medical help or contact a Poison Control Center right away.

Directions

adults and children 12 years and over: apply to affected area not more than 3 to 4 times daily children under 12 years: ask a doctor

Inactive ingredients

glyceryl stearate, isoceteth-20, poloxamer, purified water, sodium lauryl sulfate, sorbitan monostearate, trolamine Questions Call: 1-888-287-1915

Questions?

Call: 1-888-287-1915

— FDA label of Equate Cool and Heat, Wal-Mart Stores Inc, effective December 17, 2024. See the official label on DailyMed →

This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.

Same medicine, other brands

Each group lists the products that have exactly the same active ingredients, in the same amount and form, as registered with the FDA (NDC Directory). A store brand in the same group has the same medicine as the name brand; inactive ingredients, flavors and package sizes can differ. Each product links to its own official label.

Menthol 10% · Methyl salicylate 15% · cream (topical) · 16 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Analgesic Balm Geri-Care Pharmaceuticals, Corp DailyMed
Arthritis Hot Chattem, Inc. DailyMed
AsperFlex Akron Pharma Inc. DailyMed
Calypxo HP Pain Relief Asclemed USA, Inc DailyMed
CAREALL Muscle Rub Ultra Strength New World Imports, Inc DailyMed
CVS Muscle Rub CVS Health DailyMed
Dr Sheffield Muscle Rub Cream NuCare Pharmaceuticals, Inc. DailyMed
Dr Sheffield Muscle Rub Cream Sheffield Pharmaceuticals LLC DailyMed
DynaRub Dynarex Corporation DailyMed
Medi-First Muscle Rub Cream Unifirst First Aid Corporation DailyMed
Muscle Rub Aldermed Inc. —
Muscle Rub Rugby Laboratories —
Muscle Rub Cream Allied Trade Link LLC DailyMed
Muscle Rub Cream Trifecta Pharmaceuticals USA, LLC. DailyMed
Pain Reliever Cream Trifecta Pharmaceuticals USA, LLC. DailyMed
Rugby Muscle Rub Cream NuCare Pharmaceuticals, Inc. DailyMed
Menthol 14.5% · Methyl salicylate 30% · oil (topical) · 11 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Eagle Brand Medicated Oil Borden Company (Private) Limited DailyMed
Eagle Brand Medicated Oil Pt. Eagle Indo Pharma DailyMed
Eagle Brand Medicated Roll On Borden Company (Private) Limited DailyMed
Eagle Brand Medicated Roll On Pt. Eagle Indo Pharma DailyMed
Eagle Medicated Borden Company (Private) Limited DailyMed
Eagle Medicated Eagle Indo Pharma DailyMed
Eagle Medicated Eagle Indo Pharma, PT DailyMed
Menthol 100 mg/mL · Methyl salicylate 200 mg/mL · cream (topical) · 5 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Careland Pain Relief Planet (Anhui) Pharmaceutical Co., Ltd. DailyMed
RockSauce Warming Massage Implus Footcare, LLC DailyMed
RockSauce Warming Massage Nantong Health & Beyond Hygienic Products Inc. DailyMed
RockSauce Warming Massage Roll On Nantong Health & Beyond Hygienic Products Inc. DailyMed
Menthol 100% · Methyl salicylate 100% · cream (topical) · 4 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Rayo Active Heat Quimicas Handal de Centroamerica SA de CV DailyMed
Menthol 3% · Methyl salicylate 10% · cream (topical) · 4 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Numbing FlexiGo Inc DailyMed
Calypxo Pain Relief Advanced Rx of Tennessee, LLC DailyMed
Calypxo Pain Relief Asclemed USA, Inc DailyMed
Geliga Muscular Pt. Eagle Indo Pharma DailyMed
Menthol, unspecified form 10% · Methyl salicylate 30% · cream (topical) · 4 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
CVS Health Cold and Hot Pain Relieving Extra Strength CVS Pharmacy DailyMed
Equate Cool and Heat Wal-Mart Stores Inc DailyMed
Family Wellness Hot and Cold Pain Relief FAMILY DOLLAR (Family Wellness) —
Meijer Extra Strength Cold And Hot TherapyPain Relieving Topical Analgesic Meijer Distribution, Inc DailyMed
Menthol 20 mg/mL · Methyl salicylate 100 mg/mL · cream (topical) · 3 products
Brand or product nameCompany on the labelLabel
5Kind DMSO 5kind Trading Ltd DailyMed
Capasil Pain Relieving PureTek Corporation DailyMed
Mencylate Pain Relieving PureTek Corporation DailyMed
Menthol 10% · Methyl salicylate 18% · cream (topical) · 3 products
Brand or product nameCompany on the labelLabel
Heating Pain Relief Chemco Corporation DailyMed
Heating Pain Relief Sunset Novelties, Inc DailyMed
Menthol 14.5% · Methyl salicylate 30% · liquid (topical) · 3 products
Brand or product nameCompany on the labelLabel
Eagle Brand Muscle Rub Borden Company (Private) Limited DailyMed
Eagle Brand Muscle Rub Pt. Eagle Indo Pharma DailyMed
Eagle Extra Strength Borden Company (Private) Limited DailyMed
Menthol, unspecified form 10% · Methyl salicylate 15% · cream (topical) · 3 products
Brand or product nameCompany on the labelLabel
Muscle Rub Cream Preferred Pharmaceuticals Inc. DailyMed
Rugby Muscle Rub Cream Preferred Pharmaceuticals Inc. DailyMed
TheraCare Muscle and Join Pain Relieving Cream Veridian Healthcare DailyMed
Menthol, unspecified form 6% · Methyl salicylate 10% · patch (topical) · 3 products
Brand or product nameCompany on the labelLabel
BT Pain Relief Big 5 Nutrition LLC DailyMed
Herbal Utaplas External Analgesic Plaster Big 5 Nutrition LLC DailyMed
Muscle Meltdown External Analgesic Plaster Big 5 Nutrition LLC DailyMed
Menthol 63 mg · Methyl salicylate 210 mg · patch (percutaneous, topical, transdermal) · 2 products
Brand or product nameCompany on the labelLabel
Salonpas Arthritis Pain Hisamitsu Pharmaceutical Co., Inc. DailyMed
Salonpas Pain Relief Hisamitsu Pharmaceutical Co., Inc. DailyMed
Menthol 31.5 mg · Methyl salicylate 105 mg · patch (percutaneous, topical, transdermal) · 2 products
Brand or product nameCompany on the labelLabel
Salonpas Arthritis Pain Hisamitsu Pharmaceutical Co., Inc. DailyMed
Salonpas Pain Relief Hisamitsu Pharmaceutical Co., Inc. DailyMed
Menthol 40 mg/mL · Methyl salicylate 100 mg/mL · cream (topical) · 2 products
Brand or product nameCompany on the labelLabel
NanoX Pain Relieving MG Science Technologies LLC DailyMed
NanoXtreme Pain Relieving MG Science Technologies LLC DailyMed
Menthol 2.24 g/112 g · Methyl salicylate 11.2 g/112 g · cream (topical) · 2 products
Brand or product nameCompany on the labelLabel
Arctic Heat Renu Laboratories, LLC DailyMed
Extreme Emu Renu Laboratories, LLC DailyMed
Menthol 14% · Methyl salicylate 15% · oil (topical) · 2 products
Brand or product nameCompany on the labelLabel
Eagle Medicated Oil Refreshing Borden Company (Private) Limited DailyMed
Eagle Medicated Oil Refreshing Eagle Indo Pharma, PT DailyMed
Menthol 100 mg/mL · Methyl salicylate 50 mg/mL · liquid (topical) · 2 products
Brand or product nameCompany on the labelLabel
Dit Da Shui Big 5 Nutrition LLC DailyMed
UtaSpray Big 5 Nutrition LLC DailyMed
Menthol 2% · Methyl salicylate 10% · gel (topical) · 2 products
Brand or product nameCompany on the labelLabel
Doloflex Pain Relief United Health & Beauty Corp DailyMed
Rugged Fit Pain Relief Roll On System4book LLC DailyMed
Menthol 10% · Methyl salicylate 30% · cream (topical) · 2 products
Brand or product nameCompany on the labelLabel
Icy Hot Pain Relieving Cream Chattem, Inc. DailyMed
Signature Care Cold and Hot Safeway Inc. DailyMed
Menthol 13.5% · Methyl salicylate 29.95% · ointment (topical) · 2 products
Brand or product nameCompany on the labelLabel
Eagle Brand Muscular Balm Pt. Eagle Indo Pharma DailyMed
Geliga Muscular Balm Pt. Eagle Indo Pharma DailyMed

59 more strengths and forms are listed in the FDA NDC Directory.

What pharmacies pay (NADAC)

The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.

This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.

NADAC per unit for Menthol and methyl salicylate, by strength and form
Strength and formGeneric or brandPharmacies pay
menthol 10% · methyl salicylate 15%
cream
Generic $0.0364 per gram
menthol, unspecified form 1% · methyl salicylate 15%
cream
Generic $0.0445 per gram

NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.

Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →

Companies that sell this medicine

The company named on the package (maker or distributor), as listed in the FDA NDC Directory, with its number of over-the-counter products of this medicine.

  • Borden Company (Private) Limited10 products
  • Big 5 Nutrition LLC9 products
  • Pt. Eagle Indo Pharma8 products
  • Hisamitsu Pharmaceutical Co., Inc.5 products
  • Quimicas Handal de Centroamerica SA de CV4 products
  • Sunset Novelties, Inc3 products
  • Implus Footcare, LLC3 products
  • Chattem, Inc.3 products
  • Veridian Healthcare3 products
  • Trifecta Pharmaceuticals USA, LLC.3 products
  • Rugby Laboratories3 products
  • Haw Par Healthcare Ltd.3 products
  • 5Kind Trading Ltd2 products
  • Laboratorios Dr. Collado, S.A2 products
  • STL International Inc2 products
  • Timing Pharmaceutical Co., Ltd PABP Branch2 products
  • PureTek Corporation2 products
  • Delon Laboratories (1990) Ltd2 products
  • MG Science Technologies LLC2 products
  • Cosco International, Inc2 products
  • Renu Laboratories, LLC2 products
  • Eagle Indo Pharma, PT2 products
  • NuCare Pharmaceuticals, Inc.2 products
  • Asclemed USA, Inc2 products
  • Nantong Health & Beyond Hygienic Products Inc.2 products
  • The Mentholatum Company2 products
  • Preferred Pharmaceuticals Inc.2 products
  • Isagenix International, LLC1 product
  • Ideaz, LLC1 product
  • International Nature Nutraceuticals, Inc.1 product

Showing the 30 companies with the most products, of 79.

Recalls

From FDA enforcement reports, matched by the product’s NDC code or label. A recall usually covers specific products or lots: check the name and lot number on your package.

  1. April 24, 2025 · Class II · Terminated · D-0421-2025

    CGMP Deviations

    Artridon Glucosamine (menthol 2% and Methyl Salicylate 15% - Topical Analgesic), for arthritis joint pain relief, 5 oz (142g) Tube, Dist by/por: Pharmadel LLC, New Castle, DE, 19720, Made in India, NDC 55758-030-05, UPC — KENIL HEALTHCARE PRIVATE LIMITED

  2. July 6, 2015 · Class III · Terminated · D-1233-2015

    Subpotent Drug: menthol and methyl salicylate below specification

    Maximum Strength Analgesic Thera-Gesic Pain Relieving Creme Relief from: Joint and Muscle Soreness, Arthritis, Back Aches; 1/8 Oz Sachet, OTC, Manufactured for Mission Pharmacal Company 10999 IH 10 West, Suite 1000 San A — BioComp Pharma, Inc.

Next steps

Sources

  1. Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  2. NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  3. Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
  4. FDA rule for the Drug Facts label (21 CFR 201.66)

Only medicines marketed under FDA rules for nonprescription drugs (an FDA monograph or an FDA approval) are listed. Homeopathic products are not listed: the FDA does not evaluate them for safety or effectiveness.

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