Quick answers
- What is Lidocaine and phenylephrine used for?
- The Drug Facts label of Serynth Hemorrhoid (Jiangxi Yudexi Pharmaceutical Co., Ltd) lists these uses: Temporarily shrink hemorrhoidal tissue, relieving pain,soreness, burning, itching, anddiscomfort associated with hemorrhoids..
- Do I need a prescription for Lidocaine and phenylephrine?
- No. The products on this page are sold without a prescription (over the counter).
- Is a store brand the same as the name brand?
- Products listed together below have the same active ingredients, in the same amount and the same form, as registered with the FDA. Inactive ingredients (such as colors, flavors and fillers) and package sizes can differ. Compare the “Active ingredient” box on both packages, and ask a pharmacist if you are not sure.
- Has Lidocaine and phenylephrine been recalled?
- No recall linked to these products appears in the FDA enforcement reports we use.
Drug Facts label
Every over-the-counter medicine must carry a “Drug Facts” box in the same order, set by FDA rules. Below is the label of one product for each common strength and form, quoted word for word. Your own package can differ (for example, children’s products have other directions): always follow the label on your package.
Serynth Hemorrhoid · Jiangxi Yudexi Pharmaceutical Co., Ltd
Lidocaine 4% · Phenylephrine hydrochloride 0.25%, cream (topical)
Active ingredient
Lidocaine 4% Phenylephrine HCL 0.25%
Purpose
Analgesic (pain relief) Vasoconstrictor
Uses
Temporarily shrink hemorrhoidal tissue, relieving pain,soreness, burning, itching, anddiscomfort associated with hemorrhoids.
Warnings
For external use only, including the skin aroundthe anal canal
Do not use
Do not put this product into the rectum. Ask Doctor
Stop use and ask a doctor if
condition worsens or does not improve within seven days, bleeding occurs, an allergic reaction develops, the symptom being treated does not subside or if redness, irritation, swelling, pain or other symptoms develop or increase. When Using
When using this product
do not exceed recommended daily dosage unless directed by a doctor, when using finger cots or an applicator, apply externally or the skin of the anal canal only. Stop Use
Ask a doctor before use if
you have allergies to any of the components of this product, difficulty in urination due to enlargement of the prostate gland, diabetes, heart disease, high blood pressure, thyroid disease, or presently taking a prescription for high blood pressure or depression. Other information
If pregnant or breast-feeding
ask a health care professional before use. Keep Oot Of Reach Of Children If swallowed, seek medical help or contact a Poison Control Center right away.
Directions
Children under 12 years of age consult your pediatrician. Adults: apply to affected area up to 3 times daily.Clean affected area with mild soap and warm water, rinse thoroughly, and then gently dry (patting or blotting) with tissue or soft cloth before use. To use dispensing cap, attach it to tube, lubricate well then gently insert part way into anus and squeeze tube to deliver medication. Thoroughly cleanse dispensing cap after use with mild soap and warm water and rinse thoroughly.
Inactive ingredients
Borneol,Carbomer Homopolymer,Chlorhexidine Acetate ，Glycerin, Thymol, Aloe
— FDA label of Serynth Hemorrhoid, Jiangxi Yudexi Pharmaceutical Co., Ltd, effective July 24, 2026. See the official label on DailyMed →
tina davies IceJelly Hemorrhoidal · Tina Davies Professional LLC
Lidocaine 5% · Phenylephrine hydrochloride 0.25%, cream (topical)
Active ingredient
Lidocaine 5% w/v Phenylephrine HCl 0.25% w/v
Purpose
Local anesthetic Vasoconstrictor
Uses
- for the temporary relief of:
- local itching and discomfort associated with hemorrhoids
- burning
- pain
- soreness
- temporarily reduces the swelling associated with irritation in hemorrhoids and other anorectal disorders.
- temporarily shrinks hemorrhoidal tissue.
Warnings
For external use only Allergy alert : certain persons can develop allergic reactions to ingredients in this product. If the symptom being treated does not subside or if redness, irritation, swelling, pain, or other symptoms develop or increase, discontinue use and consult a doctor.
Ask a doctor before use if
you have
- heart disease
- high blood pressure
- thyroid disease
- diabetes
- difficulty in urination due to enlargement of the prostate gland
Ask a doctor or pharmacist before use if
you are
- presently taking a prescription drug for high blood pressure or depression.
When using this product
- do not exceed the recommended daily dosage unless directed by a doctor.
- do not put this product into the rectum by using fingers or any mechanical device or applicator.
- in case of bleeding, consult a doctor promptly.
Stop use and ask a doctor if
- condition worsens or does not improve within 7 days.
- an allergic reaction develops.
If pregnant or breast-feeding
ask a health professional before use.
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away.
Directions
- adults: when practical, cleanse the affected area with mild soap and warm water and rinse thoroughly. Gently dry by patting or blotting with toilet tissue or a soft cloth before application of this product.
- apply externally to the affected area up to 4 times daily.
- children under 12 years of age: ask a doctor.
Inactive ingredients
D&C Red No. 33, Disodium EDTA, Glycerin, Hydroxyethylcellulose, L-Cysteine HCl, Panthenol, Phenoxyethanol, Purified Water.
Questions?
1-888-510-1388 You may also report serious side effects to this phone number. Mon - Fri 9:00 AM - 5:00 PM
— FDA label of tina davies IceJelly Hemorrhoidal, Tina Davies Professional LLC, effective June 11, 2026. See the official label on DailyMed →
The Femme Fix Hemorrhoid Treatment · Poppy Collective LLC
Lidocaine 4% · Phenylephrine hydrochloride 0.25%, ointment (topical)
Active ingredient
Lidocaine 4% Phenylephrine HCL 0.25% Purpose Local Anesthetic Vasoconstrictor
Purpose
Local Anesthetic Vasoconstrictor
Uses
–Helps relieve the pain, itching, and burning associated with hemorrhoids. –Temporarily reduce the swelling associated with irritated hemorrhoidal tissue and other anorectal disorders. –Temporarily provides a coating for relief of anorectal discomforts. –Temporarily protects irritated areas and inflamed perianal skin.
Warnings
For external use only. Allergy Alert Certain persons can develop allergic reactions to ingreadients in this product
Ask a doctor before use if
you have: –Heart disease; high blood pressure; thyroid disease; diabetes. –Difficulty in urination due to enlargement of the prostate gland.
Ask a doctor or pharmacist before use if
you are presently taking a prescription drug for high blood pressure or depression.
When using this product
–Avoid contact with eyes. –Do not exceed recommended daily dosage unless directed by a doctor. –Do not put this product into the rectum by using fingers or any mechanical device or applicator.
Stop use and ask a doctor if
–Bleeding occurs. –Condition worsens or does not improve within 7 days. –Allergic reaction occurs to ingredients in this product. –Symptom being treated does not subside or if redness, irritation, swelling, pain or other symptoms develop or increase.
If pregnant or breast-feeding
ask a doctor before use.
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away.
Directions
–When practical, cleanse the affected area with mild soap and warm water and rinse thoroughly. Gently dry by patting or blotting with toilet tissue or soft cloth before applying. –Adults and children 12 years and older: apply externally to the affected area up to 4 times daily. –Children under 12 years of age: consult a doctor.
Inactive ingredients
alcohol, aloe barbadensis leaf extract, beeswax, BHA, C12-15 alkyl benzoate, caprylic/capric triglyceride, caprylyl glycol, citric acid, cocos nucifera (coconut) oil, euphorbia cerifera (candelilla) wax, glycerin, glyceryl laurate, glyceryl undecylenate, hamamelis virginiana (witch hazel) water, helianthus annuus (sunflower) seed oil, lanolin, lanolin alcohol, lavandula angustifolia (lavender) flower oil, magnesium sulfate, petrolatum, tapioca starch, water (aqua).
— FDA label of The Femme Fix Hemorrhoid Treatment, Poppy Collective LLC, effective May 27, 2025. See the official label on DailyMed →
Walgreens Pain Relief with Lidocaine · Walgreens Co
Lidocaine 5% · Phenylephrine hydrochloride 0.25%, spray (topical)
Active ingredient
Lidocaine 5%, Phenylephrine HCl 0.25%
Purpose
Hemorrhoidal (Anorectal)
Uses
Helps relieve the local itching and discomfort associated with anorectal disorders or inflammation.
Warnings
For external use only. Flammable.
Do not use
while smoking or near heat or flame.
When using this product
avoid contact with eyes, do not exceed recommended dosage unless directed by a doctor, do not put this product into the rectum by using fingers or any mechanical device or applicator.
Stop use and ask a doctor if
rectal bleeding occurs, condition worsens or does not improve within 7 days, allergic reaction occurs to ingredients in this product, symptom being treated does not subside or if redness, irritation, swelling, pain or other symptoms develop or increase. Ask a professional before use. If swallowed, get medical help or contact a Poison Control Center right away.
Directions
When practical, cleanse the affected area with mild soap and warm water, rinse thoroughly and gently pat dry, spray affected area, wash hands after applying. Adults and children 12 years and older: apply externally to the affected area up to 4 times a day. Children under 12 years of age: consult a doctor.
Inactive ingredients
Alcohol denat., aloe barbadensis leaf extract, citric acid, disodium EDTA, glycerin, malic acid, menthol, propyl gallate, propylene glycol, sodium benzoate, water
— FDA label of Walgreens Pain Relief with Lidocaine, Walgreens Co, effective April 1, 2026. See the official label on DailyMed →
Terramed Just Think Comfort Hemorrhoidal Wipes · Rida LLC
Lidocaine 5% · Phenylephrine hydrochloride 0.25%, cloth (topical)
Active ingredient
Purpose Lidocaine 5% (w/w) Local anesthetic Phenylephrine HCl 0.25% (w/w) Vasoconstrictor
Uses
For the temporary relief of pain, soreness, burning, and itching associated with hemorrhoids. Temporarily relieves the inflamed tissue and reduces the swelling associated with hemorrhoidal tissue. Temporarily provides a cooling sensation for relief of anorectal discomfort.
Warnings
For external use only.
Do not use
- in or near the mouth
- in the eyes
- if you are allergic to lidocaine, phenylephrine, or any ingredients in this product
Ask a doctor before use if
you have :
- heart disease
- high blood pressure
- thyroid disease
- diabetes
- difficulty in urination due to enlargement of the prostate gland
- bleeding from the rectum
Ask a doctor or pharmacist before use if
you are presently taking a prescription drug. Phenylephrine may interact with certain prescription drugs.
When using this product
- wash hands after use
- avoid contact with the eyes; if eye contact occurs, rinse thoroughly with water
- do not exceed recommended dose
- do not put this product into the rectum by using fingers or any mechanical device or applicator
Stop use and ask a doctor if
- bleeding occurs
- the symptom being treated does not subside or if redness, irritation, swelling, pain, or other symptoms develop or increase
- condition worsens or does not improve within 7 days
- an allergic reaction develops
If pregnant or breast-feeding
ask a health professional before use.
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away (1-800-222-1222).
Directions
Adults and children 12 years of age and older:
- when practical, cleanse the affected area with mild soap and warm water and rinse thoroughly
- gently dry by patting or blotting with toilet tissue or a soft cloth before applying the wipe
- unfold one wipe and gently apply to the affected area by patting, then discard
- apply externally to the affected area up to 6 times daily Children under 12 years of age: ask a doctor.
Inactive ingredients
Aloe Barbadensis Leaf Juice, Anhydrous Citric Acid, Edetate Disodium, Glycerin, Propylene Glycol, Purified Water, Sodium Benzoate.
— FDA label of Terramed Just Think Comfort Hemorrhoidal Wipes, Rida LLC, effective June 8, 2026. See the official label on DailyMed →
Treatonic hemorrhoid treatment · 100 Karma Inc
Lidocaine 2.5 g/50 g · Phenylephrine hydrochloride 0.125 g/50 g, cream (topical)
Active ingredient
Lidocaine 5% Phenylephrine HCI 0.25%
Purpose
Topical anesthetic Vasoconstrictor
Uses
Adults: When practical, cleanse the affected area with mild soap and warm water and rinse thoroughly. Gently dry by patting or blotting with toilet tissue or a soft cloth before application of this product. Children under 12 years of age: consult a doctor. For External use: Apply externally to the affected area up to 4 times daily. For Intrarectal use: Attach applicator to tube. Lubricate applicator well, then gently insert applicator into the rectum. Apply to the affected area up to 4 times daily.
Warnings
For external and / or intrarectal use only.
Ask a doctor or pharmacist before use if
you are presently taking a prescription drug for high blood pressure or depression.
Do not use
this product if you have heart disease, high blood pressure, thyroid disease, diabetes or difficulty in urination due to enlargement of the prostate gland unless directed by a doctor.
Do not use
this product with an applicator if the introduction of the applicator into the rectum causes additional pain. Consult a doctor promptly. lf the condition worsens or does not improve within 7 days, consult a doctor. Do not exceed the recommended daily dosage unless directed by a doctor. In case of bleeding, consult a doctor promptly. Certain persons can develop allergic reactions to ingredients in this product. If the symptombeing treated does not subside or if redness, irritation, swelling, pain, or other symptoms develop or increase, discontinue use and consult a doctor.
Keep out of reach of children
, if swallowed, get medical help or contact poison control center right away.
Directions
For the temporary relief of local and anorectal itching and discomfort associated with anorectal disorders and anorectal inflammation. For the temporary reliefofpain, burning and soreness. Temporarily shrinks hemorrhoidal tissue. Temporarily reduces the swelling associated with irritation in hemorrhoids and other anorectal disorders.
Other information
Keep away from direct sunlight or heat. Store at room temperature 15°-30°C(59°-86°F). This package is child-resistant. Keep out of reach of children. In case of accidental overdose or ingestion, call a doctor or poison control center immediately.
Inactive ingredients
Water, Ethylhexyl Palmitate, Zinc Oxide, Glycerin, Propylene Glycol, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Glyceryl Stearate, Gentiana Scabra Root Extract, Centella Asiatica Extract, Menthol, PEG-100 Stearate, Carbomer, Allantoin, Salvia Miltiorrhiza Root Extract, Angelica Polymorpha Sinensis Root Extract, Eugenia Caryophyllus (Clove) Bud Extract, Glycyrrhiza Uralensis (Licorice) Root Extract, Dendrobium Officinale Stem Extract, Stephania Tetrandra Extract, Aesculus Hippocastanum (Horse Chestnut) Extract, Taxus Cuspidata Leaf Extract, Smilax Glabra Root Extract, Glycyrrhiza Glabra (Licorice) Root Extract, Potassium Alum, Caprylhydroxamic Acid, Phenoxyethanol.
— FDA label of Treatonic hemorrhoid treatment, 100 Karma Inc, effective August 12, 2026. See the official label on DailyMed →
This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.
Same medicine, other brands
Each group lists the products that have exactly the same active ingredients, in the same amount and form, as registered with the FDA (NDC Directory). A store brand in the same group has the same medicine as the name brand; inactive ingredients, flavors and package sizes can differ. Each product links to its own official label.
Lidocaine 4% · Phenylephrine hydrochloride 0.25% · cream (topical) · 7 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Alveora HEMORRHOID MASTER | Jiangxi Yudexi Pharmaceutical Co., Ltd | DailyMed |
| Dermfree Hemorrhoid | Jiangxi Yudexi Pharmaceutical Co., Ltd | DailyMed |
| Dr.Harry COMFORT ZONE Cream | Jiangxi Yudexi Pharmaceutical Co., Ltd | DailyMed |
| Natucure HEMORRHOID | Jiangxi Yudexi Pharmaceutical Co., Ltd | DailyMed |
| Nicovito Hemorrhoid Master | Jiangxi Yudexi Pharmaceutical Co., Ltd | DailyMed |
| Serynth Hemorrhoid | Jiangxi Yudexi Pharmaceutical Co., Ltd | DailyMed |
| Vamy HEMORRHOID | Jiangxi Yudexi Pharmaceutical Co., Ltd | DailyMed |
Lidocaine 5% · Phenylephrine hydrochloride 0.25% · cream (topical) · 4 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Hemorrohoid Master Cream | Ebanel Laboratories, Inc. | DailyMed |
| Liposomal Hemorrhoid Master | Clinical Resolution Laboratory, Inc. | DailyMed |
| tina davies IceCream Hemorrhoidal | Tina Davies Professional LLC | DailyMed |
| tina davies IceJelly Hemorrhoidal | Tina Davies Professional LLC | DailyMed |
Lidocaine 4% · Phenylephrine hydrochloride 0.25% · ointment (topical) · 4 products
Lidocaine 5% · Phenylephrine hydrochloride 0.25% · spray (topical) · 4 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| DCH Rapid Relief Hemorrhoidal | Derma Care Research Labs | DailyMed |
| Lidocaine Phenylephrine | Yyba Corp | DailyMed |
| Preparation H Rapid Relief | Haleon US Holdings LLC | DailyMed |
| Walgreens Pain Relief with Lidocaine | Walgreens Co | DailyMed |
Lidocaine 5% · Phenylephrine hydrochloride 0.25% · cloth (topical) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Terramed Just Think Comfort Hemorrhoidal Wipes | Rida LLC | DailyMed |
Lidocaine 2.5 g/50 g · Phenylephrine hydrochloride 0.125 g/50 g · cream (topical) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Treatonic hemorrhoid treatment | 100 Karma Inc | DailyMed |
Lidocaine 5% · Phenylephrine hydrochloride 0.25% · gel (rectal) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Zensa Numbing Gel | Alera Skin Care Products Inc. | DailyMed |
Lidocaine 50 mg/mL · Phenylephrine hydrochloride 2.5 mg/mL · gel (topical) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Comfort Candy Hemorrhoidal | Bowler Esthetics, Inc | DailyMed |
Lidocaine 0.4% · Phenylephrine hydrochloride 0.25% · ointment (topical) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Hemorrhoid Master | Clinical Resolution Laboratory, Inc. | DailyMed |
Lidocaine 5% · Phenylephrine hydrochloride 0.25% · ointment (topical) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Dr.Seymour Butts Hemorrhoid | Jiangxi Yudexi Pharmaceutical Co., Ltd | DailyMed |
Lidocaine 50 mg/mL · Phenylephrine hydrochloride 2.5 mg/mL · spray (topical) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Numb520 | Clinical Resolution Laboratory, Inc. | DailyMed |
Lidocaine 50 mg/mL · Phenylephrine hydrochloride 2.5 mg/mL · liquid (topical) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Numb520Spray | Ebanel Laboratories, Inc. | DailyMed |
Lidocaine 5% · Phenylephrine hydrochloride 0.25% · gel (topical) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| SECONDARY NUMB Lidocaine Phenylephrine Gel | LALANI Rx Consulting, Inc. | DailyMed |
Lidocaine 4% · Phenylephrine hydrochloride 0.025% · cream (topical) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Healmusz Hemorrhoid Fissure | Jiangxi Yudexi Pharmaceutical Co., Ltd | DailyMed |
Lidocaine hydrochloride 500% · Phenylephrine hydrochloride 25% · spray (topical) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Curist 5% Lidocaine | Little Pharma, Inc. | DailyMed |
Lidocaine hydrochloride 5% · Phenylephrine hydrochloride 0.25% · cream (topical) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Tina Davies IceCream | Tina Davies Professional LLC | DailyMed |
Lidocaine 4% · Phenylephrine 0.25% · ointment (topical) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Hemorrhoid Master | Ebanel Laboratories, Inc | DailyMed |
Lidocaine 5% · Phenylephrine 0.25% · ointment (rectal) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Verdibliss HEMORRHOID RELIEF OINTMENTS | Guangdong Quadrant Ecological Technology Co., Ltd. | DailyMed |
Companies that sell this medicine
The company named on the package (maker or distributor), as listed in the FDA NDC Directory, with its number of over-the-counter products of this medicine.
- Jiangxi Yudexi Pharmaceutical Co., Ltd9 products
- Clinical Resolution Laboratory, Inc.3 products
- Tina Davies Professional LLC3 products
- Ebanel Laboratories, Inc3 products
- Derma Care Research Labs2 products
- Poppy Collective LLC2 products
- Rida LLC1 product
- 100 Karma Inc1 product
- Alera Skin Care Products Inc.1 product
- Bowler Esthetics, Inc1 product
- Yyba Corp1 product
- Beyond Health P.A.1 product
- LALANI Rx Consulting, Inc.1 product
- Walgreens Co1 product
- Haleon US Holdings LLC1 product
- Little Pharma, Inc.1 product
- Guangdong Quadrant Ecological Technology Co., Ltd.1 product
Recalls
No recall linked to these products (by their NDC code or label) appears in the FDA enforcement reports.
Sources
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- FDA rule for the Drug Facts label (21 CFR 201.66)
Only medicines marketed under FDA rules for nonprescription drugs (an FDA monograph or an FDA approval) are listed. Homeopathic products are not listed: the FDA does not evaluate them for safety or effectiveness.