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Over-the-counter medicine · no prescription needed

Hypromellose 2910 (4000 mpa.s)

Purpose on the label: Eye Lubricant Eye Lubricant

Eye care

Official FDA data, not advice

The label text is quoted exactly as the company filed it with the U.S. Food and Drug Administration (FDA), with a link to the official copy. The list of brands comes from the FDA NDC Directory.

This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.

If someone may have taken too much, call Poison Help: 1‑800‑222‑1222. In an emergency, call 911.

Quick answers

What is Hypromellose 2910 (4000 mpa.s) used for?
The Drug Facts label of Systane (Alcon Laboratories, Inc.) lists these uses: for the temporary relief of burning and irritation due to dryness of the eye for use as a protectant against further irritation or to relieve dryness of the eye.
Do I need a prescription for Hypromellose 2910 (4000 mpa.s)?
No. The products on this page are sold without a prescription (over the counter).
Is a store brand the same as the name brand?
Products listed together below have the same active ingredient, in the same amount and the same form, as registered with the FDA. Inactive ingredients (such as colors, flavors and fillers) and package sizes can differ. Compare the “Active ingredient” box on both packages, and ask a pharmacist if you are not sure.
Has Hypromellose 2910 (4000 mpa.s) been recalled?
FDA enforcement reports list 3 recalls of products on this page; the newest started September 17, 2026. A recall usually concerns specific products or lots, not every brand.

Drug Facts label

Every over-the-counter medicine must carry a “Drug Facts” box in the same order, set by FDA rules. Below is the label of one product for each common strength and form, quoted word for word. Your own package can differ (for example, children’s products have other directions): always follow the label on your package.

Systane · Alcon Laboratories, Inc.

Hypromellose 2910 (4000 mpa.s) 0.3%, gel (ophthalmic)

Active ingredient

Purpose Hypromellose (0.3%) Lubricant

Purpose

Active ingredient Purpose Hypromellose (0.3%) Lubricant

Uses

for the temporary relief of burning and irritation due to dryness of the eye for use as a protectant against further irritation or to relieve dryness of the eye

Warnings

For external use only

Do not use

if this product changes color or becomes cloudy if you are sensitive to any ingredient in this product

When using this product

do not touch tip of container to any surface to avoid contamination replace cap after using

Stop use and ask a doctor if

you experience any of the following: eye pain changes in vision continued redness or irritation of the eye condition worsens or persists for more than 72 hours

Keep out of reach of children

If swallowed, get medical help or contact a Poison Control Center right away.

Directions

put 1 or 2 drops in the affected eye(s) as needed

Other information

store at room temperature

Inactive ingredients

carbopol 980, phosphonic acid, purified water, sodium perborate and sorbitol. May contain sodium hydroxide to adjust pH.

Questions?

In the U.S. call 1-800-757-9195 alcon.medinfo@alcon.com www.systane.com

— FDA label of Systane, Alcon Laboratories, Inc., effective December 15, 2023. See the official label on DailyMed →

Splash Tears · Laboratorios Sophia, S.A. De C.V.

Hypromellose 2910 (4000 mpa.s) 0.2%, solution/ drops (ophthalmic)

Active ingredient

Hypromellose 0.2%

Purpose

Lubricant eye drops

Uses

Temporarily relieves burning and irritation due to dryness of the eye. discomfort due to minor irritations of the eye or to exposure to wind or sun.

Warnings

For external use only.

Do not use

if solution changes color or becomes cloudy.

When using this product

do not touch tip of container to any surface to avoid contamination. replace cap after using.

Stop use and ask a doctor if

you experience eye pain, changes in vision, continued redness or irritation of the eye. condition worsens or persists for more than 72 hours.

Keep out of reach of children

If swallowed, get medical help or contact a Poison Control Center right away.

Directions

instill 1 or 2 drops in the affected eye(s) as needed

Inactive ingredients

benzalkonium chloride, boric acid, chondroitin sulfate, edetate disodium, magnesium chloride, polysorbate 80, potassium chloride, sodium borate, sodium chloride, water for injection

Questions?

Call 1-866-282-8871 www.splashtears.com

— FDA label of Splash Tears, Laboratorios Sophia, S.A. De C.V., effective May 8, 2026. See the official label on DailyMed →

Alcon Tears Lubricant Eye Drops · Alcon Laboratories, Inc.

Hypromellose 2910 (4000 mpa.s) 5 mg/mL, solution/ drops (ophthalmic)

Active ingredient

Active i ngredients Purpose Hypromellose 2910 0.5% Lubricant

Purpose

Active i ngredients Purpose Hypromellose 2910 0.5% Lubricant

Uses

for the temporary relief of burning and irritation due to dryness of the eye for use as a protectant against further irritation

Warnings

For external use only

Do not use

if this solution changes color or becomes cloudy if you are sensitive to any ingredient in this product

When using this product

remove contact lenses before using to avoid contamination, do not touch tip of container to any surface replace cap after each use

Stop use and ask a doctor if

you experience any of the following: eye pain changes in vision continued redness or irritation condition worsens or persists for more than 72 hours

Keep out of reach of children

If swallowed, get medical help or contact a Poison Control Center right away.

Directions

instill 1 or 2 drops in the affected eye(s) as needed

Other information

store at room temperature

Inactive ingredients

benzalkonium chloride 0.01% as preservative, dibasic sodium phosphate, monobasic sodium phosphate, purified water, sodium chloride, sodium citrate

Questions?

In the U.S. call 1-800-757-9195

— FDA label of Alcon Tears Lubricant Eye Drops, Alcon Laboratories, Inc., effective December 14, 2023. See the official label on DailyMed →

Focus PI · Covalent Medical

Hypromellose 2910 (4000 mpa.s) 7 mg/mL, for solution (ophthalmic)

Active ingredient

Hypromellose 0.7% BP w/v

Purpose

Eye Lubricant Eye Lubricant

Uses

For use as a lubricant to prevent further irritation or to relieve dryness of the eye Indications and Usage For use as a lubricant to prevent further irritaion or to relieve dryness of the eye

Warnings

For External Use Only DO NOT USE If you are sensitive to any ingredient in this product If solution changes color or becomes cloudy ASK DOCTOR If you experience eye pain Change in vision Continued redness(or) irritation of the eye Condition worsens or persists for more than 72 hours KEEP OUT OF REACH OF CHILDREN If swallowed, get medical help or contact a poison control center right away

Directions

Dosage Instill 1 or 2 drops in the affected eyes as needed

Other information

Tamper Protection For your protection a tamper evident ring is attached to the bottlecap Upon opening, this will separate from the cap and can be discarded Use only if this ring is present and attached when the bottle is first opened

Inactive ingredients

Benzalkonium Chloride Borax Boric acid EDTA disodium salt Potassium chloride Purified water Sodiumchloride

Questions?

Questions Call: 855-663-6287 Email: Info@focusvitamins.com Web: www.focusvitamins.com

— FDA label of Focus PI, Covalent Medical, effective March 9, 2026. See the official label on DailyMed →

HylaTears · Hyalogic LLC

Hypromellose 2910 (4000 mpa.s) 3 mg/10 mL, liquid (ophthalmic)

Active ingredient

Hypromellose 0.3% Lubricant List of active ingredients

Purpose

Lubricant Purpose

Uses

Inidication and Use For the temporary relief of burning, irritaiton and discomofrt due to drynes of the eye or exposure to wind and sun,. May be uysed as a protectant against further irritation Indication and Use

Warnings

For external use only. If you are pregnant, nursing, trying to conceive, taking any medications, or have a medical condition, please consult your healthcare practitioner before using this product.

Stop use and ask a doctor if

You experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours.

Do not use

if solution changes color or becomes cloudy. If swallowed, get medical help or contact a Poison Control Center right away.

Keep out of reach of children

Warnings Keep out of Reach

Keep out of reach of children

Keep out of Reach

Directions

Instill one or two drops in the affected eye(s) as needed. Dosage and Administration

Inactive ingredients

Water, sodium chloride, sodium hyaluron-ate, potassium chloride, sodium phosphate dibasic, sodium phosphate monobasic, benzyl alcohol. Inactive Ingredients

— FDA label of HylaTears, Hyalogic LLC, effective January 10, 2025. See the official label on DailyMed →

Hypromellose Eye Drops 0.7% · Aurolab

Hypromellose 2910 (4000 mpa.s) 7 mg/mL, for solution (topical)

Active ingredient

Hypromellose 0.7% BP w/v

Purpose

Eye Lubricant Eye Lubricant

Uses

For use as a lubricant to prevent further irritation or to relieve dryness of the eye Indications and Usage For use as a lubricant to prevent further irritaion or to relieve dryness of the eye

Warnings

For External Use Only DO NOT USE If you are sensitive to any ingredient in this product If solution changes color or becomes cloudy ASK DOCTOR If you experience eye pain Change in vision Continued redness(or) irritation of the eye Condition worsens or persists for more than 72 hours KEEP OUT OF REACH OF CHILDREN If swallowed, get medical help or contact a poison control center right away

Directions

Dosage Instill 1 or 2 drops in the affected eyes as needed

Other information

Tamper Protection For your protection a tamper evident ring is attached to the bottlecap Upon opening, this will separate from the cap and can be discarded Use only if this ring is present and attached when the bottle is first opened

Inactive ingredients

Benzalkonium Chloride Borax Boric acid EDTA disodium salt Potassium chloride Purified water Sodiumchloride

Questions?

Call: 1-800-103-7321 Email: info@aurolab.com Web: www.aurolab.com

— FDA label of Hypromellose Eye Drops 0.7%, Aurolab, effective January 2, 2025. See the official label on DailyMed →

This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.

Same medicine, other brands

Each group lists the products that have exactly the same active ingredient, in the same amount and form, as registered with the FDA (NDC Directory). A store brand in the same group has the same medicine as the name brand; inactive ingredients, flavors and package sizes can differ. Each product links to its own official label.

Hypromellose 2910 (4000 mpa.s) 0.3% · gel (ophthalmic) · 2 products

Drug Facts for this strength and form ↑

Hypromellose 2910 (4000 mpa.s) 0.2% · solution/ drops (ophthalmic) · 2 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Splash Refresh Laboratorios Sophia, S.A. De C.V. DailyMed
Splash Tears Laboratorios Sophia, S.A. De C.V. DailyMed
Hypromellose 2910 (4000 mpa.s) 5 mg/mL · solution/ drops (ophthalmic) · 1 product

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Alcon Tears Lubricant Eye Drops Alcon Laboratories, Inc. DailyMed
Hypromellose 2910 (4000 mpa.s) 7 mg/mL · for solution (ophthalmic) · 1 product

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Focus PI Covalent Medical DailyMed
Hypromellose 2910 (4000 mpa.s) 3 mg/10 mL · liquid (ophthalmic) · 1 product

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
HylaTears Hyalogic LLC DailyMed
Hypromellose 2910 (4000 mpa.s) 7 mg/mL · for solution (topical) · 1 product

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Hypromellose Eye Drops 0.7% Aurolab DailyMed

What pharmacies pay (NADAC)

The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.

This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.

NADAC per unit for Hypromellose 2910 (4000 mpa.s), by strength and form
Strength and formGeneric or brandPharmacies pay
hypromellose 2910 (4000 mpa.s) 0.3%
gel
Brand: GenTeal Tears Severe $0.9037 per gram
hypromellose 2910 (4000 mpa.s) 0.3%
gel
Brand: Systane $0.9037 per gram
hypromellose 2910 (4000 mpa.s) 5 mg/mL
solution/ drops
Generic $2.08 per mL

NADAC list of November 4, 2026; these prices took effect between August 19, 2026 and October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.

Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →

Companies that sell this medicine

The company named on the package (maker or distributor), as listed in the FDA NDC Directory, with its number of over-the-counter products of this medicine.

  • Alcon Laboratories, Inc.3 products
  • Laboratorios Sophia, S.A. De C.V.2 products
  • Covalent Medical1 product
  • Hyalogic LLC1 product
  • Aurolab1 product

Recalls

From FDA enforcement reports, matched by the product’s NDC code or label. A recall usually covers specific products or lots: check the name and lot number on your package.

  1. September 17, 2026 · Class II · Ongoing · D-0874-2026

    Lack of Assurance of Sterility

    FOCUS PI Hypromellose 0.7% Formula, 0.3 FL O (10 mL) per vial, STERILE, Manufactured for: Covalent Management, Inc., Manassas, VA 20109. NDC: 82724-007-19 — Aurolab Trust

  2. April 21, 2026 · Class II · Ongoing · D-0491-2026

    Lack of Assurance of Sterility: Due to FDA inspection observations that it believes may impact product quality.

    Systane, Lubricant Eye Gel, Night Gel, Sterile, 10g (0.35 oz), Processed in France for: Alcon Laboratiroes, Inc., Fort Worth, TX 76134, USA, NDC 0065-0474-01 — Alcon Research LLC

  3. April 21, 2026 · Class II · Ongoing · D-0492-2026

    Lack of Assurance of Sterility: Due to FDA inspection observations that it believes may impact product quality.

    GenTeal Tears, Lubricant Eye Gel, Sterile, 10g (0.34 Fl oz), Distributed by: Alcon Laboratories, Inc., Fort Worth, Texas 76134, USA, NDC: 0065-8064-01. — Alcon Research LLC

Sources

  1. Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  2. NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  3. Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
  4. FDA rule for the Drug Facts label (21 CFR 201.66)

Only medicines marketed under FDA rules for nonprescription drugs (an FDA monograph or an FDA approval) are listed. Homeopathic products are not listed: the FDA does not evaluate them for safety or effectiveness.

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