Quick answers
- What is Guaifenesin and phenylephrine used for?
- The Drug Facts label of Sunmark Chest Congestion Relief PE PE (Strategic Sourcing Services LLC) lists these uses: Temporarily relieves symptoms associated with a cough ,the common cold,hay fever or other upper respiratory allergies.; helps loosen phlegm (mucus); clear nasal passageways; loosens nasal congestion; drain bronchial tubes; shrinks swollen membranes; clears stuffy nose; makes coughs more productive.
- Do I need a prescription for Guaifenesin and phenylephrine?
- No. The products on this page are sold without a prescription (over the counter).
- Is a store brand the same as the name brand?
- Products listed together below have the same active ingredients, in the same amount and the same form, as registered with the FDA. Inactive ingredients (such as colors, flavors and fillers) and package sizes can differ. Compare the “Active ingredient” box on both packages, and ask a pharmacist if you are not sure.
- Has Guaifenesin and phenylephrine been recalled?
- No recall linked to these products appears in the FDA enforcement reports we use.
Drug Facts label
Every over-the-counter medicine must carry a “Drug Facts” box in the same order, set by FDA rules. Below is the label of one product for each common strength and form, quoted word for word. Your own package can differ (for example, children’s products have other directions): always follow the label on your package.
Sunmark Chest Congestion Relief PE PE · Strategic Sourcing Services LLC
Guaifenesin 400 mg · Phenylephrine hydrochloride 10 mg, tablet (oral)
Active ingredient
- (per tablet) Guaifenesin 400 mg Phenylephrine HCl 10 mg
Purpose
Guaifenesin.......................Expectorant Phenylephrine HCl..............Nasal decongestant
Uses
Temporarily relieves symptoms associated with a cough ,the common cold,hay fever or other upper respiratory allergies.
- helps loosen phlegm (mucus)
- clear nasal passageways
- loosens nasal congestion
- drain bronchial tubes
- shrinks swollen membranes
- clears stuffy nose
- makes coughs more productive
Warnings
Do not exceed recommended dosage
Do not use
- this product if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson’s Disease), or for 2 weeks after stopping the MAOI drug. If you are uncertain whether your prescription drug contains an MAOI, ask a health professional.
Ask a doctor before use if
you have
- heart disease
- high blood pressure
- thyroid disease
- diabetes
- excessive phlegm;mucus
- difficulty in urination due to an enlarged prostate gland
- persistent or chronic cough such as occurs with smoking,asthma,chronic bronchitis or emphysema
Stop use and ask a doctor if
- nervousness, dizziness or sleeplessness occurs
- symptoms are accompanied by fever, rash, persistent headache or excessive phlegm (mucus)
- cough and congestion do not improve within 7 days or tend to recur. These could be signs of a serious condition .
If pregnant or breast-feeding
ask a health professional before use. Keep out of the reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.
Directions
- adults and children 12 years and over: take 1 caplet every 4 hours as needed
- children 6 to under 12 years: take 1/2 caplet every 4 hours as needed
- children under 6 years: consult a doctor Do not exceed 6 doses in a 24 hour period or as directed by a doctor.
Inactive ingredients
lactose, magnesium silicate, croscarmellose sodium, hypromellose, magnesium stearate, maltodextrin, microcrystalline cellulose, mineral oil, povidone, silica, sodium lauryl sulfate, stearic acid, titanium dioxide and triacetin image of carton
— FDA label of Sunmark Chest Congestion Relief PE PE, Strategic Sourcing Services LLC, effective December 18, 2024. See the official label on DailyMed →
Cvs · Cvs Pharmacy, Inc
Guaifenesin 100 mg/5 mL · Phenylephrine hydrochloride 2.5 mg/5 mL, solution (oral)
Active ingredient
Drug Facts Active ingredients (in each 5 mL) Guaifenesin, USP 100 mg Phenylephrine HCl, 2.5 mg
Purpose
Expectorant Nasal Decongestant
Uses
- helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive
- temporarily relieves:
- nasal congestion due to a cold
- stuffy nose
Warnings
Do not use
in a child who is taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your child’s prescription drug contains an MAOI, ask a doctor or pharmacist before giving this product.
Ask a doctor before use if
the child has
- heart disease
- high blood pressure
- thyroid disease
- diabetes
- cough that occurs with too much phlegm (mucus)
- persistent or chronic cough such as occurs with asthma
When using this product
Do not use
more than directed
Stop use and ask a doctor if
- your child gets nervous, dizzy or sleepless
- symptoms do not get better within 7 days or occur with fever
- cough lasts more than 7 days, comes back, or occurs with fever, rash, or persistent headache. These could be signs of a serious illness.
Keep out of reach of children
In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222).
Directions
do not give more than 6 doses in any 24 hour period
- measure only with dosing cup provided
- do not use dosing cup with other products
- mL= milliliter
| Age | Dose |
| Children 6 years to under 12 years | 10 mL every 4 hours |
| Children 4 years to under 6 years | 5 mL every 4 hours |
| Children under 4 years | do not use |
Inactive ingredients
anhydrous citric acid, edetate disodium, flavors, glycerin, propylene glycol, purified water, sodium benzoate, sodium citrate, sorbitol solution, sucralose, xanthan gum.
Questions?
1-866-467-2748
— FDA label of Cvs, Cvs Pharmacy, Inc, effective August 19, 2026. See the official label on DailyMed →
Mucus Relief PE · Walgreen Company
Guaifenesin 400 mg · Phenylephrine hydrochloride 10 mg, tablet, film coated (oral)
Active ingredient (in each immediate-release tablet)
Guaifenesin 400 mg Phenylephrine HCl 10 mg
Purpose
Expectorant Nasal decongestant
Uses
helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive temporarily relieves nasal congestion due to the common cold, hay fever or other upper respiratory allergies promotes nasal and/or sinus drainage temporarily relieves sinus congestion and pressure
Warnings
Do not use
if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
Ask a doctor before use if
you have heart disease high blood pressure thyroid disease diabetes difficulty in urination due to enlargement of the prostate gland cough accompanied by too much phlegm (mucus) persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema
When using this product
do not exceed recommended dosage.
Stop use and ask a doctor if
nervousness, dizziness, or sleeplessness occur symptoms do not improve within 7 days or are accompanied by fever cough persists more than 7 days, tends to recur, or is accompanied by a fever, rash, or persistent headache. These could be signs of a serious condition.
If pregnant or breast-feeding
ask a health professional before use.
Keep out of reach of children
In case of overdose, get medical help or contact a Poison Control Center right away.
Directions
take with a full glass of water adults and children 12 years and over: 1 tablet every 4 hours. Do not take more than 6 tablets in 24 hours. children under 12 years: do not use
Inactive ingredients
hypromellose, magnesium stearate, maltodextrin, microcrystalline cellulose, polyethylene glycol, povidone, silicon dioxide, sodium starch glycolate, stearic acid
Questions?
1-800-426-9391
— FDA label of Mucus Relief PE, Walgreen Company, effective August 4, 2026. See the official label on DailyMed →
Deconex IR · Poly Pharmaceuticals, Inc.
Guaifenesin 385 mg · Phenylephrine hydrochloride 10 mg, tablet (oral)
Active ingredient
Guaifenesin 385 mg Active ingredients Phenylephrine HCl 10 mg
Purpose
Expectorant Purpose Nasal Decongestant
Uses
Temporarily relieves these symptoms due to the common cold, hay fever (allergic rhinitis) or other respiratory allergies: helps loosen phlegm and thin bronchial secretions to make coughs more productive nasal congestion runny nose sneezing itching of the nose or throat itchy, watery eyes
Warnings
Do not exceed recommended dosage. A persistent cough may be a sign of a serious condition. If cough persists for more than 1 week, tends to recur, or is accompanied by fever, rash, or persistent headache, consult a doctor.
Ask a doctor before use if
you have a persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema, or if cough is accompanied by excessive phlegm heart disease high blood pressure thyroid disease diabetes difficulty in urination due to enlargement of the prostate gland
Ask a doctor before use if
you are taking sedatives or tranquilizers.
Stop use and ask a doctor if
nervousness, dizziness or sleeplessness occur
Ask a doctor or pharmacist before use if
you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. If pregnant or breast feeding, ask a health professional before use.
Keep out of reach of children
In case of overdose, get medical help or contact a Poison Control Center right away.
Directions
Adults and children 12 years of age and older: 1 tablet every 4 hours, not to exceed 6 tablets in 24 hours. Children age 6 to 12 years of age: 1/2 tablet every 4 hours, not to exceed 3 tablets in 24 hours or as directed by a doctor. Children 6 years of age and younger: Consult a physician.
Inactive ingredients
FD&C Yellow No. 5, FD&C Blue No. 1, magnesium stearate, microcrystalline cellulose, sodium starch glycolate. Manufactured for: Poly Pharmaceuticals Huntsville, AL 35763 (800) 882-1041 Rev. 06/16
— FDA label of Deconex IR, Poly Pharmaceuticals, Inc., effective July 9, 2024. See the official label on DailyMed →
Tusnel Pediatric Drops · Llorens Pharmaceuticals International Division
Guaifenesin 25 mg/mL · Phenylephrine hydrochloride 1.25 mg/mL, solution/ drops (oral)
Active ingredient
in each (1 mL) Guaifenesin 25 mg Phenylephrine HCl 1.25 mg
Purpose
Expectorant Nasal Decongestant
Uses
Temporarily relieves nasal congestion due to the common cold and thin bronchial secretions to make coughs more productive Helps loosen phlegm (mucus) and thin bronchial secretions to make cough more productive.
Warnings
Do not use
in child whos is taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your child's prescription drug contains an MAOI: ask your doctor or pharmacist before giving this product.
Ask a doctor before use if
your child has heart disease high blood pressure thyroid disease diabetes a cough that occurs with too much phlegm a persistent or chronic cough that occurs with asthma, or if cough is accompanied by excessive phlegm (mucus) unless directed by a doctor.
When using this product
do not exceed the recommended dosage. Stop use and ask doctor if nervousness, dizziness or sleeplessness occurs symptoms do not get better within 7 days or accompanied by fever cough lasts more than 7 days, comes back, or is accompanied by fever, rash or persistent headache. A persistent cough may be a sign of a serious condition.
Keep out of reach of children
In case overdose, get medical help or contact a Poison Control Center right away.
Directions
Do not exceed more than 4 doses in any 24-hour period or as directed by a doctor.
| Age | Weight | Dose |
| Children 2 to under 6 years of age | 24-47 lbs | Take 2 mL every 4-6 hours |
| Children under 2 years of age | Under 24 lbs | Ask a doctor |
Inactive ingredients
Artifical and natural flavor, citric acid, glycerin, methylparaben, polyethylene glycol, propylene glycol, propylparaben, purified water, sodium citrate, sucralose.
Questions?
1-866-595-5598
— FDA label of Tusnel Pediatric Drops, Llorens Pharmaceuticals International Division, effective December 31, 2025. See the official label on DailyMed →
SUPRESS-PE Pediatric · Kramer Novis
Guaifenesin 50 mg/mL · Phenylephrine hydrochloride 2.5 mg/mL, solution/ drops (oral)
Active ingredient (in each 1 mL)
Guaifenesin, 50 mg Phenylephrine HCl, 2.5 mg
Purpose
Expectorant Nasal decongestant
Uses
- helps loosen phlegm (mucus) and thin bronchial secretions to drain bronchial tubes and make coughs more productive
- temporarily relieves nasal congestion due to the common cold
Warnings
Do not use
in a child who is taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your child's prescription drug contains a MAOI, ask a doctor or pharmacist before giving this product.
Ask a doctor before use if
the child has
- heart disease
- thyroid disease
- high blood pressure
- diabetes
- cough that occurs with too much phlegm (mucus)
- cough that lasts or is chronic such as occurs with asthma.
When using this product
do not exceed recommended dosage.
Stop use and ask a doctor if
- your child gets nervous, dizzy, or sleepless
- symptoms do not get better within 7 days or are accompanied by fever
- cough lasts more than 7 days, comes back, or is accompanied by fever, rash or persistent headache. These could be signs of a serious condition.
Keep out of reach of children
In case of accidental overdose, get medical help or contact a Poison Control Center right away.
Directions
- do not use more than 6 doses in any 24-hour period.
- repeat every 4 hours.
- measure with the dosage device provided. Do not use with any other device.
- children 2 to under 6 years of age, 1 mL.
- children under 2 years of age, consult a doctor.
Inactive ingredients
Citric acid, glycerin, grape flavor, methylparaben, polyethylene glycol, propylene glycol, propylparaben, purified water, sodium citrate, sucralose, sucrose.
Questions?
call weekdays from 8 am to 4 pm AST at 1.787.767.2072
— FDA label of SUPRESS-PE Pediatric, Kramer Novis, effective March 26, 2025. See the official label on DailyMed →
This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.
Same medicine, other brands
Each group lists the products that have exactly the same active ingredients, in the same amount and form, as registered with the FDA (NDC Directory). A store brand in the same group has the same medicine as the name brand; inactive ingredients, flavors and package sizes can differ. Each product links to its own official label.
Guaifenesin 400 mg · Phenylephrine hydrochloride 10 mg · tablet (oral) · 7 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Always Save Mucus Relief PE | Valu Merch | DailyMed |
| CVS Health Chest Congestion Relief PE | CVS Pharmacy, Inc. | DailyMed |
| Foster and Thrive Chest Congestion Relief PE PE | Strategic Sourcing Services LLC | DailyMed |
| GNP Mucus Relief PE | AmerisourceBergen Drug Corp | DailyMed |
| Rugby Chest Congestion Relief PE | Rugby Laboratories | — |
| Sunmark Chest Congestion Relief PE PE | Strategic Sourcing Services LLC | DailyMed |
| Topcare Chest Congestion and Sinus Congestion Relief PE | Topco Associates LLC | DailyMed |
Guaifenesin 100 mg/5 mL · Phenylephrine hydrochloride 2.5 mg/5 mL · solution (oral) · 4 products
Guaifenesin 400 mg · Phenylephrine hydrochloride 10 mg · tablet, film coated (oral) · 2 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Mucus Relief PE | Walgreen Company | DailyMed |
| Mucus Relief PE Sinus Congestion | Cardinal Health 110, LLC. DBA Leader | — |
Guaifenesin 385 mg · Phenylephrine hydrochloride 10 mg · tablet (oral) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Deconex IR | Poly Pharmaceuticals, Inc. | DailyMed |
Guaifenesin 25 mg/mL · Phenylephrine hydrochloride 1.25 mg/mL · solution/ drops (oral) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Tusnel Pediatric Drops | Llorens Pharmaceuticals International Division | DailyMed |
Guaifenesin 50 mg/mL · Phenylephrine hydrochloride 2.5 mg/mL · solution/ drops (oral) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| SUPRESS-PE Pediatric | Kramer Novis | DailyMed |
Guaifenesin 400 mg · Phenylephrine hydrochloride 10 mg · tablet, coated (oral) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Pharbinex-PE | Ulai Health LLC | DailyMed |
Guaifenesin 388 mg · Phenylephrine hydrochloride 10 mg · tablet (oral) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Giltuss Sinus and Chest Congestion | Gil Pharmaceutical Corp | DailyMed |
Guaifenesin 390 mg · Phenylephrine hydrochloride 10 mg · tablet (oral) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Gilphex | Gil Pharmaceutical Corp. | DailyMed |
What pharmacies pay (NADAC)
The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.
This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.
| Strength and form | Generic or brand | Pharmacies pay |
|---|---|---|
| guaifenesin 400 mg · phenylephrine hydrochloride 10 mg tablet | Generic | $0.0927 per tablet |
| guaifenesin 400 mg · phenylephrine hydrochloride 10 mg tablet, film coated | Generic | $0.0927 per tablet |
NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.
Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →
Companies that sell this medicine
The company named on the package (maker or distributor), as listed in the FDA NDC Directory, with its number of over-the-counter products of this medicine.
- Strategic Sourcing Services LLC2 products
- Cvs Pharmacy, Inc2 products
- Gil Pharmaceutical Corp.2 products
- Valu Merch1 product
- AmerisourceBergen Drug Corp1 product
- Raritan Pharmaceuticals1 product
- Rugby Laboratories1 product
- Poly Pharmaceuticals, Inc.1 product
- Llorens Pharmaceuticals International Division1 product
- Kramer Novis1 product
- Walgreen Company1 product
- Ulai Health LLC1 product
- Topco Associates LLC1 product
- Cardinal Health 110, LLC. DBA Leader1 product
- Reckitt Benckiser LLC1 product
- Walgreens Co.1 product
Recalls
No recall linked to these products (by their NDC code or label) appears in the FDA enforcement reports.
Sources
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- FDA rule for the Drug Facts label (21 CFR 201.66)
Only medicines marketed under FDA rules for nonprescription drugs (an FDA monograph or an FDA approval) are listed. Homeopathic products are not listed: the FDA does not evaluate them for safety or effectiveness.