Quick answers
- What is Ferric oxide red, pramoxine hydrochloride and zinc oxide used for?
- The Drug Facts label of Calamine Plus Pramoxine HCl (CVS Pharmacy) lists these uses: temporarily relieves pain and itching associated with: insect bites rashes minor skin irritations minor cuts dries the oozing and weeping of poison ivy, poison oak and poison sumac.
- Do I need a prescription for Ferric oxide red, pramoxine hydrochloride and zinc oxide?
- No. The products on this page are sold without a prescription (over the counter).
- Is a store brand the same as the name brand?
- Products listed together below have the same active ingredients, in the same amount and the same form, as registered with the FDA. Inactive ingredients (such as colors, flavors and fillers) and package sizes can differ. Compare the “Active ingredient” box on both packages, and ask a pharmacist if you are not sure.
- Has Ferric oxide red, pramoxine hydrochloride and zinc oxide been recalled?
- No recall linked to these products appears in the FDA enforcement reports we use.
Drug Facts label
Every over-the-counter medicine must carry a “Drug Facts” box in the same order, set by FDA rules. Below is the label of one product for each common strength and form, quoted word for word. Your own package can differ (for example, children’s products have other directions): always follow the label on your package.
Calamine Plus Pramoxine HCl · CVS Pharmacy
Ferric oxide red 0.345 mg/116 g · Pramoxine hydrochloride 2.72 mg/116 g · Zinc oxide 24.16 mg/116 g, aerosol, spray (topical)
Active ingredient
Calamine 8% Pramoxine HCl 1%
Purpose
Skin protectant External analgesic
Uses
temporarily relieves pain and itching associated with: insect bites rashes minor skin irritations minor cuts dries the oozing and weeping of poison ivy, poison oak and poison sumac
Warnings
Warnings For external use only. Flammable
Do not use
while smoking or near heat or flame. Do not puncture or incinerate. Contents under pressure. Do not store at temperatures above 120°F. Intentional misuse by deliberately concentrating and inhaling contents can be harmful or fatal. When using this product do not get into eyes ask a doctor before using on children under 2 years of age
Stop use and ask a doctor if
conditions worsens symtomps last more than 7 days or clear up and occur again in a few days Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
Directions
shake well before using adults and children 2 years of age and older: apply to affected area not more than 3 to 4 times daily cleanse the skin with soap and water let dry before use children under 2 years of age: consult a doctor
Other information
Flammable: Do not use while smoking or near heat or flame. Do not puncture or incinerate. Contents under pressure. Do not store at temperatures above 120°F. Intentional misuse by deliberately concentrating and inhaling contents can be harmful or fatal. Other information store between 20° to 25°C (68° to 77°F)
Inactive ingredients
Inactive ingredients benzyl alcohol, camphor, disteardimonium hectorite, fragrance, hydrated silica, isobutane, oleyl alcohol, SD alcohol 40-B, sorbitan trioleate
Questions?
Questions? Call 1-866-964-0939
— FDA label of Calamine Plus Pramoxine HCl, CVS Pharmacy, effective May 11, 2026. See the official label on DailyMed →
Calamine Plus Pramoxine HCl · Target Corporation
Ferric oxide red 0.5% · Pramoxine hydrochloride 1% · Zinc oxide 7.5%, aerosol, spray (topical)
Active ingredient
Calamine 8% Pramoxine HCl 1%
Purpose
Skin protectant External analgesic
Uses
temporarily relieves pain and itching associated with: insect bites rashes minor skin irritations minor cuts dries the oozing and weeping of poison ivy, poison oak and poison sumac
Warnings
For external use only. Flammable
Do not use
while smoking or near heat or flame. Do not puncture or incinerate. Contents under pressure. Do not store at temperatures above 120°F. Intentional misuse by deliberately concentrating and inhaling contents can be harmful or fatal.
When using this product
do not get into eyes ask a doctor before using on children under 2 years of age
Stop use and ask a doctor if
conditions worsens symptoms last more than 7 days or clear up and occur again in a few days
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away.
Directions
shake well before using adults and children 2 years of age and older: apply to affected area not more than 3 to 4 times daily cleanse the skin with soap and water let dry before use children under 2 years of age: consult a doctor
Other information
- Flammable: Do not use while smoking or near heat or flame. Do not puncture or incinerate. Contents under pressure. Do not store at temperatures above 120°F. Intentional misuse by deliberately concentrating and inhaling contents can be harmful or fatal. Other information store between 20° to 25°C (68° to 77°F)
Inactive ingredients
benzyl alcohol, camphor, disteardimonium hectorite, fragrance, hydrated silica, isobutane, oleyl alcohol, SD alcohol 40-B, sorbitan trioleate
Questions?
Call 1-866-964-0939
— FDA label of Calamine Plus Pramoxine HCl, Target Corporation, effective June 29, 2026. See the official label on DailyMed →
Calamine Plus · Chain Drug Marketing Association Inc
Ferric oxide red 0.5% · Pramoxine hydrochloride 1% · Zinc oxide 7.95%, aerosol, spray (topical)
Active ingredient
Calamine 8% Pramoxine HCI 1%
Purpose
Skin protectant External analgesic
Uses
temporarily relieves pain and itching associated with: insect bites rashes minor skin irritations minor cuts dries the oozing and weeping of poison ivy, poison oak and poison sumac
Warnings
For external use only. Flammable
Do not use
while smoking or near heat or flame. Do not puncture or incinerate. Contents under pressure. Do not store at temperatures above 120°F. Intentional misuse by deliberately concentrating and inhaling contents can be harmful or fatal.
When using this product
do not get into eyes ask a doctor before using on children under 2 years of age
Stop use and ask a doctor if
condition worsens symptoms last more than 7 days or clear up and occur again in a few days Keep out of the reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
Stop use and ask a doctor if
condition worsens symptoms last more than 7 days or clear up and occur again in a few days
Directions
shake well before using adults and children 2 years of age and older: apply to affected area not more than 3 to 4 times daily cleanse the skin with soap and water let dry before use children under 2 years of age: consult a doctor Other Information store between 20° to 25°C (68° to 77°F)
Other information
store between 20° to 25°C (68° to 77°F)
Inactive ingredients
benzyl alcohol, camphor, disteardimonium hectorite, fragrance, hydrated silica, isobutane, oleyl alcohol, SD alcohol 40-B, sorbitan trioleate
Questions?
Call 1-866-964-0939
— FDA label of Calamine Plus, Chain Drug Marketing Association Inc, effective November 6, 2025. See the official label on DailyMed →
Dermagesic · Llorens Pharmaceutical International Division
Ferric oxide red 0.4% · Pramoxine hydrochloride 1% · Zinc oxide 0.4%, cream (topical)
Active ingredient
Pramoxine HCl 1% Zinc Oxide 0.4% Calamine 0.4%
Purpose
Anestheric/Analgesic Skin Protectant
Uses
for temporary reilef of pain and itching associated with minor burns, sunburn, minor cuts, scrapes, insect bites or minor irritation dries the oozing and weeping of poison ivy, poison oak and poison sumac.
Warnings
For external use only. Avoid contact with the eyes Not for Pediatric use Hypersensitivity to "caine" anesthetics
Do not use
on large areas of the body with any other product containing diphenhydramine, even one taken by mouth. Ask a doctor before use on chicken pox on measles
Stop use and ask a doctor if
condition worsens or does not improve within 7 days symptoms persist for more than 7 days or clear up and occur again within a few days KEEP OUT OF REACH OF CHILDREN
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away.
Directions
Adults and children 2 years of age and older apply to affected area not more than 3 to 4 times daily Children under 2 years of age ask a doctor Do not use more often than directed
Inactive ingredients
Aloe Badbadensis Leaf juice (Aloe Vera), Avena Sativa (Oat) Kernal colloidal, cetyl stearyl alcohol, ceteareth-6, ceteareth-25, diazolidinyl urea, fragrance, menthol, methyl paraben, paraffinum liquidum, propylene glycol, propyl paraben, purified water, stearyl alcohol
Questions?
1-866-595-5598
— FDA label of Dermagesic, Llorens Pharmaceutical International Division, effective December 31, 2025. See the official label on DailyMed →
Caladryl · Bausch Health US, LLC
Ferric oxide red 1.36 mg/mL · Pramoxine hydrochloride 10 mg/mL · Zinc oxide 78.65 mg/mL, lotion (topical)
Active ingredient
Purpose Calamine 8% Skin protectant Pramoxine HCl 1% Topical analgesic
Purpose
Active ingredients Purpose Calamine 8% Skin protectant Pramoxine HCl 1% Topical analgesic
Uses
temporarily relieves pain and itching associated with: rashes due to poison ivy, poison oak or poison sumac insect bites minor skin irritation minor cuts dries the oozing and weeping of poison ivy, poison oak and poison sumac
Warnings
For external use only.
When using this product
do not get into eyes
Stop use and ask a doctor if
condition worsens or does not improve within 7 days symptoms persist for more than 7 days or clear up and occur again within a few days
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away.
Directions
shake well before use adults and children 2 years of age and older: apply to affected area not more than 3 to 4 times daily children under 2 years of age: ask a doctor
Inactive ingredients
SD alcohol 38-B, camphor, diazolidinyl urea, fragrance, hypromellose, methylparaben, polysorbate 80, propylene glycol, propylparaben, purified water, xanthan gum
Questions?
/Comments call 1-800-321-4576
— FDA label of Caladryl, Bausch Health US, LLC, effective October 17, 2024. See the official label on DailyMed →
Aveeno Anti-Itch Concentrated · Kenvue Brands LLC
Ferric oxide red 0.6 mg/mL · Pramoxine hydrochloride 10 mg/mL · Zinc oxide 29.4 mg/mL, lotion (topical)
Active ingredient
Purpose Calamine 3% Skin Protectant Pramoxine HCl 1% External Analgesic
Purpose
Active ingredients Purpose Calamine 3% Skin Protectant Pramoxine HCl 1% External Analgesic
Uses
For temporary relief of pain and itching associated with: minor burns sunburn minor cuts scrapes insect bites minor skin irritations rashes due to poison ivy, poison oak, or poison sumac Dries the oozing and weeping of poison: ivy oak sumac
Warnings
For external use only.
Do not use
on wounds or damaged skin
When using this product
do not get into eyes do not bandage tightly
Stop use and ask a doctor if
condition worsens symptoms last more than 7 days or clear up and occur again within a few days
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away.
Directions
Adults and children 2 years of age and older: Apply to affected area not more than 3 to 4 times daily. Children under 2 years of age: ask a doctor.
Inactive ingredients
Water, Glycerin, Distearyldimonium Chloride, Petrolatum, Isopropyl Palmitate, Cetyl Alcohol, Dimethicone, Camphor, Methylparaben, Sodium Chloride, Avena Sativa (Oat) Kernel Oil, Avena Sativa (Oat) Kernal Flour, Avena Sativa (Oat) Kernel Extract
Questions?
call toll-free 866-428-3366 or 215-273-8755 (collect) www.aveeno.com
— FDA label of Aveeno Anti-Itch Concentrated, Kenvue Brands LLC, effective October 29, 2025. See the official label on DailyMed →
This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.
Same medicine, other brands
Each group lists the products that have exactly the same active ingredients, in the same amount and form, as registered with the FDA (NDC Directory). A store brand in the same group has the same medicine as the name brand; inactive ingredients, flavors and package sizes can differ. Each product links to its own official label.
Ferric oxide red 0.345 mg/116 g · Pramoxine hydrochloride 2.72 mg/116 g · Zinc oxide 24.16 mg/116 g · aerosol, spray (topical) · 5 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Calamine Plus | AmerisourceBergen Drug Corporation | DailyMed |
| Calamine Plus Pramoxine HCl | CVS Pharmacy | DailyMed |
| Calamine Plus Pramoxine HCl | Kroger Co. | DailyMed |
| Calamine Plus Pramoxine HCl | Premier Brands of America, Inc. | DailyMed |
| Calamine Plus Pramoxine HCl | Topco Associates LLC | — |
Ferric oxide red 0.5% · Pramoxine hydrochloride 1% · Zinc oxide 7.5% · aerosol, spray (topical) · 4 products
Ferric oxide red 0.5% · Pramoxine hydrochloride 1% · Zinc oxide 7.95% · aerosol, spray (topical) · 2 products
Ferric oxide red 0.4% · Pramoxine hydrochloride 1% · Zinc oxide 0.4% · cream (topical) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Dermagesic | Llorens Pharmaceutical International Division | DailyMed |
Ferric oxide red 1.36 mg/mL · Pramoxine hydrochloride 10 mg/mL · Zinc oxide 78.65 mg/mL · lotion (topical) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Caladryl | Bausch Health US, LLC | DailyMed |
Ferric oxide red 0.6 mg/mL · Pramoxine hydrochloride 10 mg/mL · Zinc oxide 29.4 mg/mL · lotion (topical) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Aveeno Anti-Itch Concentrated | Kenvue Brands LLC | DailyMed |
Ferric oxide red 0.04% · Pramoxine hydrochloride 1% · Zinc oxide 7.96% · spray (topical) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Calamine Plus | Kroger Company | DailyMed |
Ferric oxide red 0.345 mg/177 mL · Pramoxine hydrochloride 2.72 mg/177 mL · Zinc oxide 24.16 mg/177 mL · aerosol, spray (topical) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Calamine Plus Pramoxine HCl | Walgreens Company | — |
What pharmacies pay (NADAC)
The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.
This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.
| Strength and form | Generic or brand | Pharmacies pay |
|---|---|---|
| ferric oxide red 0.345 mg/116 g · pramoxine hydrochloride 2.72 mg/116 g · zinc oxide 24.16 mg/116 g aerosol, spray | Generic | $0.0433 per gram |
| ferric oxide red 0.5% · pramoxine hydrochloride 1% · zinc oxide 7.95% aerosol, spray | Generic | $0.0433 per gram |
NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.
Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →
Companies that sell this medicine
The company named on the package (maker or distributor), as listed in the FDA NDC Directory, with its number of over-the-counter products of this medicine.
- Premier Brands of America, Inc.2 products
- Target Corporation1 product
- Llorens Pharmaceutical International Division1 product
- Topco Associates LLC1 product
- Chain Drug Marketing Association Inc1 product
- Hy-Vee, Inc1 product
- CVS Pharmacy1 product
- Meijer Distribution Inc.1 product
- Bausch Health US, LLC1 product
- Kenvue Brands LLC1 product
- FSA Store Inc.1 product
- Kroger Company1 product
- AmerisourceBergen Drug Corporation1 product
- Walgreens Company1 product
- Kroger Co.1 product
Recalls
No recall linked to these products (by their NDC code or label) appears in the FDA enforcement reports.
Sources
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- FDA rule for the Drug Facts label (21 CFR 201.66)
Only medicines marketed under FDA rules for nonprescription drugs (an FDA monograph or an FDA approval) are listed. Homeopathic products are not listed: the FDA does not evaluate them for safety or effectiveness.