Quick answers
- What is Dextromethorphan and doxylamine used for?
- The Drug Facts label of Tussin Nighttime Cough (Rite Aid Corporation) lists these uses: temporarily relieves cough due to minor throat and bronchial irritation as may occur with a cold; temporarily relieves these symptoms due to hay fever or other upper respiratory allergies; runny nose; sneezing; itchy, watery eyes; itching of the nose or throat; controls the impulse to cough to help you sleep.
- Do I need a prescription for Dextromethorphan and doxylamine?
- No. The products on this page are sold without a prescription (over the counter).
- Is a store brand the same as the name brand?
- Products listed together below have the same active ingredients, in the same amount and the same form, as registered with the FDA. Inactive ingredients (such as colors, flavors and fillers) and package sizes can differ. Compare the “Active ingredient” box on both packages, and ask a pharmacist if you are not sure.
- Has Dextromethorphan and doxylamine been recalled?
- No recall linked to these products appears in the FDA enforcement reports we use.
Drug Facts label
Every over-the-counter medicine must carry a “Drug Facts” box in the same order, set by FDA rules. Below is the label of one product for each common strength and form, quoted word for word. Your own package can differ (for example, children’s products have other directions): always follow the label on your package.
Tussin Nighttime Cough · Rite Aid Corporation
Dextromethorphan hydrobromide 30 mg/20 mL · Doxylamine succinate 12.5 mg/20 mL, solution (oral)
Active ingredient (in each 20 mL)
Dextromethorphan HBr, USP 30 mg Doxylamine succinate, USP 12.5 mg
Purpose
Cough suppressant Antihistamine
Uses
- temporarily relieves cough due to minor throat and bronchial irritation as may occur with a cold
- temporarily relieves these symptoms due to hay fever or other upper respiratory allergies:
- runny nose
- sneezing
- itchy, watery eyes
- itching of the nose or throat
- controls the impulse to cough to help you sleep
Warnings
Do not use
- to make a child sleepy
- if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
Ask a doctor before use if
you have
- trouble urinating due to an enlarged prostate gland
- glaucoma
- cough that occurs with too much phlegm (mucus)
- a breathing problem such as emphysema or chronic bronchitis
- persistent or chronic cough such as occurs with smoking, asthma, or emphysema
Ask a doctor or pharmacist before use if
you are taking sedatives or tranquilizers
When using this product
- do not use more than directed
- marked drowsiness may occur
- avoid alcoholic drinks
- alcohol, sedatives, and tranquilizers may increase drowsiness
- be careful when driving a motor vehicle or operating machinery
- excitability may occur, especially in children
Stop use and ask a doctor if
cough lasts for more than 7 days, comes back, or is accompanied by fever, rash, or persistent headache. A persistent cough may be a sign of a serious condition.
If pregnant or breast-feeding
ask a health professional before use.
Keep out of reach of children
In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222).
Directions
measure only with dosing cup provided
- keep dosing cup with product
- mL = milliliter
- do not take more than 4 doses in any 24-hour period
- this adult product is not intended for use in children under 12 years of age
| age | dose |
| adults and children 12 years and over | 20 mL every 6 hours |
| children under 12 years | do not use |
Inactive ingredients
anhydrous citric acid, benzoic acid, benzyl alcohol, carboxymethylcellulose sodium, FD&C blue #1, FD&C red #40, flavor, glycerin, menthol, polyethylene glycol, propylene glycol, purified water, sodium benzoate, sorbitol solution, sucralose, xanthan gum
Questions?
1-800-719-9260
— FDA label of Tussin Nighttime Cough, Rite Aid Corporation, effective September 4, 2026. See the official label on DailyMed →
Nighttime Cough · Walgreens
Dextromethorphan hydrobromide 30 mg/30 mL · Doxylamine succinate 12.5 mg/30 mL, liquid (oral)
Active ingredient (in each 30 mL)
Dextromethorphan HBr 30 mg Doxylamine succinate 12.5 mg
Purpose
Cough suppressant Antihistamine
Uses
temporarily relieves cold symptoms cough due to minor throat and bronchial irritation runny nose and sneezing
Warnings
Do not use
if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
Ask a doctor before use if
you have glaucoma cough that occurs with too much phlegm (mucus) a breathing problem or chronic cough that lasts or as occurs with smoking, asthma, chronic bronchits, or emphysema trouble urinating due to enlarged prostate gland
Ask a doctor or pharmacist before use if
you are taking sedatives or tranquilizers.
When using this product
excitability may occur, especially in children marked drowsiness may occur avoid alcoholic drinks alcohol, sedatives and tranquilizers may increase drowsiness be careful when driving a motor vehicle or operating machinery
Stop use and ask a doctor if
cough lasts more than 7 days, comes back, or is accompanied by fever, rash, or persistent headache.These could be signs of a serious condition.
If pregnant or breast-feeding
ask a health professional before use.
Keep out of reach of children
In case of overdose, get medical help or contact a Poison Control Center (1-800-222-1222) right away.
Directions
do not take more than 4 doses in any 24-hour period measure only with dosing cup provided. Do not use any other dosing device. keep dosing cup with product take only as directed mL = mililiter adults and children 12 years and over: 30 mL every 6 hours children under 12 years of age: do not use
Inactive ingredients
alcohol, citric acid, FD&C blue #1, FD&C red #40, flavor,high fructose corn syrup, polyethylene glycol, propylene glycol, purified water, saccharin sodium, sodium citrate
Questions?
Call 1-877-753-3935 Monday-Friday 9AM-5PM EST
— FDA label of Nighttime Cough, Walgreens, effective April 8, 2026. See the official label on DailyMed →
Childrens Nighttime Mucus · Walgreens
Dextromethorphan hydrobromide 10 mg · Doxylamine succinate 6.25 mg, chewable gel (oral)
Active ingredient (in each chewable gel)
Dextromethorphan HBr 10 mg Doxylamine Succinate 6.25 mg
Purpose
Cough suppressant Antihistamine
Uses
temporarily relieves cough due to minor throat and bronchial irritation as may occur with a cold controls cough to help you get to sleep temporarily relieves these symptoms due to hay fever or other upper respiratory allergies: runny nose sneezing itching of the nose or throat itchy, water eyes
Warnings
Do not use
to make a child sleepy if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
Ask a doctor before use if
the child has glaucoma cough that occurs with too much phlegm (mucus) a breathing problem or chronic cough that lasts or occurs with smoking, asthma, chronic bronchitis or emphysema trouble urinating due to enlarged prostate gland
Ask a doctor or pharmacist before use if
you are taking sedatives or tranquilizers
When using this product
do not exceed recommended dosage excitability may occur, especially in children marked drowsiness may occur avoid alcoholic drinks alcohol, sedative, and tranquilizers may increase drowsiness be caution when driving a motor vehicle or operating machinery
Stop use and ask a doctor if
cough lasts more than 7 days, comes back, or is accompanied by fever, rash, or persistent headache. These could be signs of a serious condition.
If pregnant or breast-feeding
ask a health professional before use
Keep out of reach of children
In case of overdose, get medical help or contact a Poison Control Center (1-800-222-1222) right away.
Directions
take every 4 hours, or as directed by a doctor chew thoroughly before swallowing adults and children 12 years and over: 2 chewable gels every 4 hours, not to exceed 12 chewable gels in any 24-hour period children 6 to under 12 years of age: 1 chewable gel every 4 hours, not to exceed 6 chewable gels in any 24-hour period. children under 6 years of age: do not use
Inactive ingredients
alcohol, ammonium glycyrrhizate, anhydrous citric acid, corn syrup, FD&C Blue No 1, FD&C Red No 40, flavors, glycerin, glycyrrhizin, malic acid, maltodextrin, pectin, propylene glycol, purified water, sucralose, sucrose, trisodium citrate dihydrate
Questions?
Call 1-877-753-3929 Monday-Friday 9AM-5PM EST
— FDA label of Childrens Nighttime Mucus, Walgreens, effective April 15, 2026. See the official label on DailyMed →
Childrens Robitussin Honey Nighttime Cough DM · Haleon US Holdings LLC
Dextromethorphan hydrobromide 15 mg/10 mL · Doxylamine succinate 6.25 mg/10 mL, solution (oral)
Active ingredient (in each 10mL)
Dextromethorphan HBr, USP 15 mg Doxylamine Succinate, USP 6.25 mg
Purpose
Cough Suppressant Antihistamine
Uses
temporarily relieves cough due to minor throat and bronchial irritation as may occur with a cold temporarily relieves these symptoms due to hay fever or other upper respiratory allergies: runny nose sneezing itchy, watery eyes itching of the nose or throat controls the impulse to cough to help you sleep
Warnings
Do not use
to sedate a child or to make a child sleepy if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
Ask a doctor before use if
you have trouble urinating due to an enlarged prostate gland glaucoma a cough that occurs with too much phlegm (mucus) a breathing problem or chronic cough that lasts or as occurs with smoking, asthma, chronic bronchitis or emphysema
Ask a doctor or pharmacist before use if
you are taking sedatives or tranquilizers
When using this product
do not use more than directed marked drowsiness may occur avoid alcoholic drinks alcohol, sedatives, and tranquilizers may increase drowsiness be careful when driving a motor vehicle or operating machinery excitability may occur, especially in children
Stop use and ask a doctor if
cough lasts more than 7 days, comes back, or is accompanied by fever, rash, or persistent headache. These could be signs of a serious condition.
If pregnant or breast-feeding
ask a health professional before use.
Keep out of reach of children
In case of overdose, get medical help or contact a Poison Control Center right away.
Directions
measure only with dosing cup provided keep dosing cup with product mL = milliliter do not take more than 4 doses in any 24-hour period
| age | dose |
|---|---|
| children under 6 years | do not use |
| children 6 to under 12 years | 10 mL every 6 hours |
| adults and children 12 years and older | 20 mL every 6 hours |
Inactive ingredients
anhydrous citric acid, blueberry juice concentrate, carboxymethylcellulose sodium, glycerin, lactic acid, natural and artificial flavors, natural grade A honey, polyethylene glycol, propylene glycol, purified water, sodium benzoate, sodium citrate, sodium gluconate, sucralose, xanthan gum, zinc gluconate
Questions?
call weekdays from 9 AM to 5 PM EST at 1-800-245-1040
— FDA label of Childrens Robitussin Honey Nighttime Cough DM, Haleon US Holdings LLC, effective May 13, 2025. See the official label on DailyMed →
ROBITUSSIN Nighttime Cough DM Soft CHEWS · Haleon US Holdings LLC
Dextromethorphan hydrobromide 15 mg · Doxylamine succinate 6.25 mg, tablet, chewable (oral)
Active ingredient (in each chewable tablet)
Dextromethorphan equivalent to 15 mg dextromethorphan HBr Doxylamine succinate 6.25 mg
Purpose
Cough suppressant Antihistamine
Uses
temporarily relieves cough due to minor throat and bronchial irritation as may occur with a cold temporarily relieves these symptoms due to hay fever or other upper respiratory allergies runny nose sneezing itchy, watery eyes itching of the nose or throat controls the impulse to cough to help you sleep
Warnings
Do not use
to sedate a child or to make a child sleepy if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
Ask a doctor before use if
you have trouble urinating due to an enlarged prostate gland glaucoma a cough that occurs with too much phlegm (mucus) a breathing problem or chronic cough that lasts or is chronic such as occurs with smoking, asthma, or chronic bronchitis or emphysema
Ask a doctor or pharmacist before use if
you are taking sedatives or tranquilizers
When using this product
marked drowsiness may occur avoid alcoholic drinks alcohol, sedatives, and tranquilizers may increase drowsiness be careful when driving a motor vehicle or operating machinery excitability may occur, especially in children
Stop use and ask a doctor if
cough lasts more than 7 days, comes back, or is accompanied by fever, rash, or persistent headache. These could be signs of a serious condition.
If pregnant or breast-feeding
ask a health professional before use.
Keep out of reach of children
In case of overdose, get medical help or contact a Poison Control Center right away.
Directions
do not take more than 4 doses (8 chewable tablets) in 24-hours, unless directed by a doctor. chew tablets completely before swallowing this adult product is not intended for use in children under 12 years of age
| age | dose | |
|---|---|---|
| adults and children 12 years and over | take 2 chewable tablets every 6 hours, as needed | |
| children under 12 years | do not use |
Inactive ingredients
calcium gluconate monohydrate, carboxymethylcellulose calcium, carnauba wax, corn syrup solids, crospovidone, D&C red no. 30 aluminum lake, FD&C blue no. 1 aluminum lake, glycerin, mannitol, natural and artificial flavors, pregelatinized starch, simethicone, sodium gluconate, sorbitol, sorbitol solution, sucralose, sucrose, whole dry milk
Questions?
call weekdays from 8 AM to 6 PM EST at 1-855-297-3031
— FDA label of ROBITUSSIN Nighttime Cough DM Soft CHEWS, Haleon US Holdings LLC, effective November 25, 2025. See the official label on DailyMed →
This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.
Same medicine, other brands
Each group lists the products that have exactly the same active ingredients, in the same amount and form, as registered with the FDA (NDC Directory). A store brand in the same group has the same medicine as the name brand; inactive ingredients, flavors and package sizes can differ. Each product links to its own official label.
Dextromethorphan hydrobromide 30 mg/20 mL · Doxylamine succinate 12.5 mg/20 mL · solution (oral) · 19 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| AMAZON Maximim Strength Adult Nighttime Cough DM | Amazon.Com Services LLC | DailyMed |
| Careone Tussin Dm | American Sales Company | DailyMed |
| Cough DM Nighttime | Cvs Woonsocket Prescription Center, Incorporated | DailyMed |
| Dg Health Tussin | Dolgencorp, LLC | DailyMed |
| meijer Maximum Strength Nighttime Cough DM | Meijer Distribution Inc | — |
| Nighttime Cough | Cvs Woonsocket Prescription Center, Incorporated | DailyMed |
| Nighttime Cough Dm | Cvs Woonsocket Prescription Center, Incorporated | DailyMed |
| Nighttime Cough DM | L.N.K. International, Inc. | DailyMed |
| Nighttime Cough Dm | Meijer, Inc. | DailyMed |
| Robitussin Honey Maximum Strength Nighttime Cough DM | Haleon US Holdings LLC | DailyMed |
| Robitussin Maximum Strength Nighttime Cough DM | Haleon US Holdings LLC | DailyMed |
| Topcare Tussin Dm Max | Topco Associates LLC | DailyMed |
| Tussin DM | CVS Pharmacy | DailyMed |
| Tussin DM Max Nighttime | Wal-Mart Stores Inc | DailyMed |
| Tussin DM Max NIGHTTIME | Walgreen Company | DailyMed |
| Tussin DM Nighttime | Cvs Woonsocket Prescription Center, Incorporated | DailyMed |
| Tussin Dm Nighttime Max | HyVee Inc | DailyMed |
| Tussin Nighttime Cough | Rite Aid Corporation | DailyMed |
| Walgreens Adult Nighttime Wal Tussin DM Max Maximum Strength | Walgreen Co. | DailyMed |
Dextromethorphan hydrobromide 30 mg/30 mL · Doxylamine succinate 12.5 mg/30 mL · liquid (oral) · 7 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Cough Relief Nighttime | Best Choice (Valu Merchandisers Company) | DailyMed |
| Cough Relief Nighttime | QUALITY CHOICE (Chain Drug Marketing Association) | DailyMed |
| Night Time Cough | Cvs Pharmacy, Inc | DailyMed |
| Night Time Cough | Safeway, Inc. | DailyMed |
| Night-Time COUGH RELIEF | Discount Drug Mart | — |
| Nighttime Cough | Walgreens | DailyMed |
| Nighttime Cough Relief | QUALITY CHOICE (Chain Drug Marketing Association) | DailyMed |
Dextromethorphan hydrobromide 10 mg · Doxylamine succinate 6.25 mg · chewable gel (oral) · 2 products
Dextromethorphan hydrobromide 15 mg/10 mL · Doxylamine succinate 6.25 mg/10 mL · solution (oral) · 2 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Childrens HoneyWorks Plus Nighttime Cough Syrup | Raritan Pharmaceuticals Inc | — |
| Childrens Robitussin Honey Nighttime Cough DM | Haleon US Holdings LLC | DailyMed |
Dextromethorphan hydrobromide 15 mg · Doxylamine succinate 6.25 mg · tablet, chewable (oral) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| ROBITUSSIN Nighttime Cough DM Soft CHEWS | Haleon US Holdings LLC | DailyMed |
Dextromethorphan hydrobromide 20 mg/20 mL · Doxylamine succinate 12.5 mg/20 mL · solution (oral) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| HoneyWorks Plus Adult Nighttime Cough Syrup | Raritan Pharmaceuticals Inc | — |
Dextromethorphan hydrobromide 10 mg · Doxylamine succinate 6.25 mg · tablet, chewable (oral) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Mucinex Childrens Mighty Chews Cough Nighttime | Reckitt Benckiser LLC | DailyMed |
Dextromethorphan 7.5 mg/5 mL · Doxylamine succinate 3.125 mg/5 mL · liquid (oral) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Safetussin PM Nighttime Cough relief | Kramer Laboratories | DailyMed |
Companies that sell this medicine
The company named on the package (maker or distributor), as listed in the FDA NDC Directory, with its number of over-the-counter products of this medicine.
- Cvs Woonsocket Prescription Center, Incorporated4 products
- Haleon US Holdings LLC4 products
- Walgreens2 products
- Raritan Pharmaceuticals Inc2 products
- QUALITY CHOICE (Chain Drug Marketing Association)2 products
- Safeway, Inc.1 product
- Meijer, Inc.1 product
- Topco Associates LLC1 product
- Discount Drug Mart1 product
- CVS Pharmacy1 product
- American Sales Company1 product
- Wal-Mart Stores Inc1 product
- L.N.K. International, Inc.1 product
- Walgreen Co.1 product
- HyVee Inc1 product
- Meijer Distribution Inc1 product
- Best Choice (Valu Merchandisers Company)1 product
- Walgreen Company1 product
- Amazon.Com Services LLC1 product
- Reckitt Benckiser LLC1 product
- Rite Aid Corporation1 product
- Dolgencorp, LLC1 product
- Cvs1 product
- Cvs Pharmacy, Inc1 product
- Kramer Laboratories1 product
Recalls
No recall linked to these products (by their NDC code or label) appears in the FDA enforcement reports.
Sources
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- FDA rule for the Drug Facts label (21 CFR 201.66)
Only medicines marketed under FDA rules for nonprescription drugs (an FDA monograph or an FDA approval) are listed. Homeopathic products are not listed: the FDA does not evaluate them for safety or effectiveness.