Quick answers
- What is Cocoa butter and phenylephrine used for?
- The Drug Facts label of Good Sense Hemorrhoidal (L. Perrigo Company) lists these uses: helps relieve the local itching and discomfort associated with hemorrhoids; temporarily relieves burning and shrinks hemorrhoidal tissue; temporarily provides a coating for relief of anorectal discomforts; temporarily protects the inflamed, irritated anorectal surface to help make bowel movements less painful.
- Do I need a prescription for Cocoa butter and phenylephrine?
- No. The products on this page are sold without a prescription (over the counter).
- Is a store brand the same as the name brand?
- Products listed together below have the same active ingredients, in the same amount and the same form, as registered with the FDA. Inactive ingredients (such as colors, flavors and fillers) and package sizes can differ. Compare the “Active ingredient” box on both packages, and ask a pharmacist if you are not sure.
- Has Cocoa butter and phenylephrine been recalled?
- No recall linked to these products appears in the FDA enforcement reports we use.
Drug Facts label
Every over-the-counter medicine must carry a “Drug Facts” box in the same order, set by FDA rules. Below is the label of one product for each common strength and form, quoted word for word. Your own package can differ (for example, children’s products have other directions): always follow the label on your package.
Good Sense Hemorrhoidal · L. Perrigo Company
Cocoa butter 2211 mg · Phenylephrine hydrochloride 6.5 mg, suppository (rectal)
Active ingredient (in each suppository)
Cocoa butter 88.44% Phenylephrine HCl 0.25%
Purpose
Protectant Vasoconstrictor
Uses
- helps relieve the local itching and discomfort associated with hemorrhoids
- temporarily relieves burning and shrinks hemorrhoidal tissue
- temporarily provides a coating for relief of anorectal discomforts
- temporarily protects the inflamed, irritated anorectal surface to help make bowel movements less painful
Warnings
For rectal use only
Ask a doctor before use if
you have
- heart disease
- high blood pressure
- thyroid disease
- diabetes
- difficulty in urination due to enlargement of the prostate gland
Ask a doctor or pharmacist before use if
you are presently taking a prescription drug for high blood pressure or depression.
When using this product
do not exceed the recommended daily dosage unless directed by a doctor
Stop use and ask a doctor if
- bleeding occurs
- condition worsens or does not improve within 7 days If pregnant or breast feeding, ask a health professional before use.
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away. (1-800-222-1222)
Directions
- adults: when practical, cleanse the affected area by patting or blotting with an appropriate cleansing wipe. Gently dry by patting or blotting with a tissue or a soft cloth before insertion of this product.
- detach one suppository from the strip; remove the foil wrapper before inserting into the rectum as follows:
- hold suppository with rounded end up
- see illustrations: carefully separate foil tabs by inserting tip of fingernail at end marked “peel down”
- slowly and evenly peel apart (do not tear) foil by pulling tabs down both sides, to expose the suppository
- remove exposed suppository from wrapper
- insert one suppository into the rectum up to 4 times daily, especially at night, in the morning or after each bowel movement
- children under 12 years of age: ask a doctor Other information
- store at 20-25°C (68-77°F)
Inactive ingredients
methylparaben, propylparaben, topical starch Questions or comments? 1-800-719-9260
Questions?
1-800-719-9260
— FDA label of Good Sense Hemorrhoidal, L. Perrigo Company, effective July 15, 2025. See the official label on DailyMed →
Preparation H · Haleon US Holdings LLC
Cocoa butter 2211 mg · Phenylephrine hydrochloride 6.25 mg, suppository (rectal)
Active ingredient
Cocoa butter 88.44% Phenylephrine HCl 0.25% Purposes Protectant Vasoconstrictor
Purpose
Protectant Vasoconstrictor
Uses
helps relieve the local itching and discomfort associated with hemorrhoids temporarily relieves burning and shrinks hemorrhoidal tissue temporarily provides a coating for relief of anorectal discomforts temporarily protects the inflamed, irritated anorectal surface to help make bowel movements less painful
Warnings
For rectal use only
Ask a doctor before use if
you have heart disease high blood pressure thyroid disease diabetes difficulty in urination due to enlargement of the prostate gland
Ask a doctor or pharmacist before use if
you are presently taking a prescription drug for high blood pressure or depression.
When using this product
do not exceed the recommended daily dosage unless directed by a doctor
Stop use and ask a doctor if
bleeding occurs condition worsens or does not improve within 7 days
If pregnant or breast-feeding
ask a health professional before use.
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away.
Directions
|
Figure Figure
Inactive ingredients
corn starch, methylparaben, propylparaben
Questions?
Call weekdays 9 AM to 5 PM EST at 1-800-99PrepH or 1-800-997-7374 For most recent product information, visit www.preparationh.com Pfizer, Madison, NJ 07940 USA © 2011 Pfizer Inc.
— FDA label of Preparation H, Haleon US Holdings LLC, effective March 2, 2024. See the official label on DailyMed →
Hemorrhoidal · CVS Pharmacy
Cocoa butter 2.39 g · Phenylephrine hydrochloride 6.75 mg, suppository (rectal)
Active ingredient (per suppository)
Cocoa butter 88.44% Phenylephrine hydrochloride 0.25%
Purpose
Protectant Vasoconstrictor
Uses
temporarily shrinks hemorrhoidal tissue gives temporary relief to the itching, burning and discomfort associated with hemorrhoids aids in protecting irritated anorectal areas
Warnings
For rectal use only
Ask a doctor or pharmacist before use if
you are presently taking a prescription drug for high blood pressure or depression
Ask a doctor before use if
you have heart disease thyroid disease difficulty in urination due to enlargement of the prostate gland high blood pressure diabetes
When using this product
do not exceed the recommended daily dosage unless directed by a doctor in case of bleeding or if condition worsens or does not improve within 7 days, consult a doctor promptly
If pregnant or breast-feeding
ask a health professional before use.
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away
Directions
Adults detach one suppository from the strip. Remove the wrapper before inserting into the rectum insert one suppository into the rectum up to 4 times daily, especially at night, in the morning or after each bowel movement children under 12 years of age: consult a doctor
Other information
Store at room temperature or in a cool place but not over 80°F
Inactive ingredients
corn starch, methylparaben, propylparaben
— FDA label of Hemorrhoidal, CVS Pharmacy, effective October 24, 2025. See the official label on DailyMed →
Hemorrhoidal · Graxcell Pharmaceutical, LLC
Cocoa butter 1768.8 mg · Phenylephrine hydrochloride 5 mg, suppository (rectal)
Active ingredient (per suppository)
Cocoa butter 88.44 % Phenylephrine hydrochloride 0.25 %
Purpose
Protectant Vasoconstructor
Uses
temporarily shrinks hemorrhoidal tissues gives temporary relief to the itching, burning and discomfort associated with hemorrhoids aids in protecting irritated anorectal areas
Warnings
For rectal use only
Ask a doctor or pharmacist before use if
you are presently taking a prescription drug for high blood pressure or depression
Ask a doctor before use if
you have heart disease thyroid disease high blood pressure diabetes difficulty in urination due to enlargement of the prostate gland
When using this product
do not exceed the recommended daily dosage unless directed by a doctor in case of bleeding or if condition worsens or does not improve within 7 days, consult a doctor promptly
If pregnant or breast-feeding
ask a health professional before use.
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away.
Directions
Adults detach one suppository from the strip. Remove the wrapper before inserting into the rectum. insert one suppository into the rectum up to 4 times daily, especially at night, in the morning or after each bowel movement. Children under 12 years of age: consult doctor
Inactive ingredients
methylparaben, propylparaben, starch
— FDA label of Hemorrhoidal, Graxcell Pharmaceutical, LLC, effective December 25, 2025. See the official label on DailyMed →
Hemorrhoidal cocoa butter · NeilMed Pharmaceuticals Inc.
Cocoa butter 88.44% · Phenylephrine hydrochloride 0.25%, suppository (rectal)
Active ingredient
Drug Facts : Active Ingredients (in each suppository) : Cocoa butter 88.44% Phenylephrine Hydrochloride 0.25%
Purpose
Protectant Vasoconstrictor
Uses
- helps relieve the local itching and discomfort associated with hemorrhoids
- temporarily relieves burning and shrinks hemorrhoidal tissue
- temporarily provides a coating for relief of anorectal discomforts
- temporarily protects the inflamed, irritatedanorectal surface to help make bowel movements less painful.
Warnings
For rectal use only
Ask a doctor before use if
you have
- heart disease
- high blood pressure
- thyroid disease
- diabetes
- difficulty in urination due to enlargement of prostate gland unless directed by a doctor Ask a doctor or pharmacist before use
Ask a doctor or pharmacist before use if
you are presently taking a prescription drug for high blood pressure or depression.
When using this product
- do not exceed the recommended daily dosage unless directed by a doctor
- children under 12 years of age: ask a doctor Stop use and ask doctor if
- bleeding occurs
- condition worsens or does not improve within 7 days
If pregnant or breast-feeding
ask a health professional before use.
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away. (1-800-222-1222)
Directions
- Adults: when practical, cleanse the affected area by patting or blotting with an appropriate cleansing wipe. Gently dry by patting or blotting with a tissue or a soft cloth before insertion of this product.
- detach one suppository from the strip; remove the foil wrapper before inserting into the rectum as follows:
- hold suppository with rounded end
- see illustrations; carefully separate foil tabs by inserting tip of fingernail at end marked “peel down”
- slowly and evenly peel apart (do not tear) foil by pulling tabs down both sides, to expose the suppository
- remove exposed suppository from wrapper
- insert one suppository into the rectum up to 4 times daily, especially at night, in the morning or after each bowel movement.
Inactive ingredients
methylparaben, propylparaben, topical starch
— FDA label of Hemorrhoidal cocoa butter, NeilMed Pharmaceuticals Inc., effective January 17, 2025. See the official label on DailyMed →
Walgreens Hemorrhoidal · Walgreens
Cocoa butter 1770 mg · Phenylephrine hydrochloride 5 mg, suppository (rectal)
Purpose
Drug Facts Cocoa butter (Protectant) Phenylephrine hydrochloride (Vasoconstrictor)
Uses
helps relieve the local itching and discomfort associated with hemorrhoids temporarily relieves burning and shrinks hemorrhoidal tissue temporarily provides a coating for relief of anorectal discomforts temporarily protects the inflamed, irritated anorectal surface to help make bowel movements less painful
Warnings
For rectal use only
Ask a doctor before use if
you have
Ask a doctor before use if
you have heart disease high blood pressure thyroid disease diabetes difficulty in urination due to enlargement of the prostate gland unless directed by a doctor
Ask a doctor or pharmacist before use if
you are
Ask a doctor or pharmacist before use if
you are presently taking a prescription drug for high blood pressure or depression
When using this product
do not exceed the recommended daily dosage unless directed by a doctor
Stop use and ask a doctor if
bleeding occurs or if condition worsens or does not improve within 7 days
If pregnant or breastfeeding
If pregnant or breastfeeding
ask a health professional before use.
Keep out of reach of children
If swallowed, get medical help or contact a Poison Control Center right away. (1-800-222-1222)
Directions
Adults When practical, cleanse the affected area by patting or blotting with an appropriate cleansing wipe. Gently dry by patting or blotting with a tissue or a soft cloth before insertion of this product. Detach one suppository from the strip; remove the foil wrapper before inserting into the rectum as follows: hold suppository with rounded end up as shown, carefully separate foil tabs by inserting tip of fingernail at end marked "peel down" slowly and evenly peel apart (do not tear) foil by pulling tabs down both sides, to expose from wrapper insert on suppository into the rectum up to 4 times daily, especially at night, in the morning or after each bowel movement Children under 12 years of age: ask a doctor
Inactive ingredients
corn starch, methylparaben, propylparaben
— FDA label of Walgreens Hemorrhoidal, Walgreens, effective June 25, 2026. See the official label on DailyMed →
This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.
Same medicine, other brands
Each group lists the products that have exactly the same active ingredients, in the same amount and form, as registered with the FDA (NDC Directory). A store brand in the same group has the same medicine as the name brand; inactive ingredients, flavors and package sizes can differ. Each product links to its own official label.
Cocoa butter 2211 mg · Phenylephrine hydrochloride 6.5 mg · suppository (rectal) · 18 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Basic Care Hemorrhoidal | Amazon.com Services LLC | DailyMed |
| Equaline Hemorrhoidal | United Natural Foods, Inc. dba UNFI | DailyMed |
| Equate Hemorrhoidal | Wal-Mart Stores Inc | DailyMed |
| Exchange Select Hemorrhoidal | Army & Air Force Exchange Service | DailyMed |
| Foster and Thrive Hemorrhoidal | Strategic Sourcing Services LLC | DailyMed |
| Good Sense Hemorrhoidal | L. Perrigo Company | DailyMed |
| Hemorrhoidal | CVS Pharmacy | — |
| Hemorrhoidal | H E B | DailyMed |
| Hemorrhoidal | HyVee Inc | DailyMed |
| Hemorrhoidal | Kroger Company | DailyMed |
| Hemorrhoidal | Meijer Distribution Inc | DailyMed |
| Hemorrhoidal | Publix Super Markets Inc | DailyMed |
| Hemorrhoidal Relief | Rite Aid Corporation | DailyMed |
| Leader Hemorrhoidal | Cardinal Health 110, LLC. dba Leader | DailyMed |
| Rexall Hemorrhoidal | Dolgencorp Inc | DailyMed |
| Rugby Hemorrhoidal | Rugby Laboratories | DailyMed |
| Signature Care Hemorrhoidal | Safeway | DailyMed |
| Topcare Hemorrhoidal | Topco Associates LLC | DailyMed |
Cocoa butter 2211 mg · Phenylephrine hydrochloride 6.25 mg · suppository (rectal) · 3 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Preparation H | Haleon US Holdings LLC | DailyMed |
| Walgreens Hemorrhoidal | Walgreens | DailyMed |
Cocoa butter 2.39 g · Phenylephrine hydrochloride 6.75 mg · suppository (rectal) · 3 products
Cocoa butter 1768.8 mg · Phenylephrine hydrochloride 5 mg · suppository (rectal) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Hemorrhoidal | Graxcell Pharmaceutical, LLC | DailyMed |
Cocoa butter 88.44% · Phenylephrine hydrochloride 0.25% · suppository (rectal) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Hemorrhoidal cocoa butter | NeilMed Pharmaceuticals Inc. | DailyMed |
Cocoa butter 1770 mg · Phenylephrine hydrochloride 5 mg · suppository (rectal) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Walgreens Hemorrhoidal | Walgreens | DailyMed |
Cocoa butter 88.5% · Phenylephrine hydrochloride 0.26% · suppository (rectal) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Xyralid Hemorrhoidal | Innovus Pharmaceuticals, Inc. | DailyMed |
What pharmacies pay (NADAC)
The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.
This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.
| Strength and form | Generic or brand | Pharmacies pay |
|---|---|---|
| cocoa butter 2.39 g · phenylephrine hydrochloride 6.75 mg suppository | Generic | $0.2856 per suppository |
| cocoa butter 2211 mg · phenylephrine hydrochloride 6.5 mg suppository | Generic | $0.2856 per suppository |
NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.
Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →
Companies that sell this medicine
The company named on the package (maker or distributor), as listed in the FDA NDC Directory, with its number of over-the-counter products of this medicine.
- Walgreens2 products
- Haleon US Holdings LLC2 products
- CVS Pharmacy2 products
- Amazon.com Services LLC1 product
- Meijer Distribution Inc1 product
- Strategic Sourcing Services LLC1 product
- Wal-Mart Stores Inc1 product
- Graxcell Pharmaceutical, LLC1 product
- NeilMed Pharmaceuticals Inc.1 product
- Army & Air Force Exchange Service1 product
- HyVee Inc1 product
- Topco Associates LLC1 product
- Innovus Pharmaceuticals, Inc.1 product
- Rugby Laboratories1 product
- L. Perrigo Company1 product
- United Natural Foods, Inc. dba UNFI1 product
- Amerisourcebergen Drug Corporation1 product
- Publix Super Markets Inc1 product
- Rite Aid Corporation1 product
- Safeway1 product
- Dolgencorp Inc1 product
- Pharmacy Value Alliance LLC1 product
- Cardinal Health 110, LLC. dba Leader1 product
- Kroger Company1 product
- H E B1 product
Recalls
No recall linked to these products (by their NDC code or label) appears in the FDA enforcement reports.
Sources
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- FDA rule for the Drug Facts label (21 CFR 201.66)
Only medicines marketed under FDA rules for nonprescription drugs (an FDA monograph or an FDA approval) are listed. Homeopathic products are not listed: the FDA does not evaluate them for safety or effectiveness.