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Over-the-counter medicine · no prescription needed

Carboxymethylcellulose and glycerin

Purpose on the label: Eye lubricant Eye lubricant

Eye care

Official FDA data, not advice

The label text is quoted exactly as the company filed it with the U.S. Food and Drug Administration (FDA), with a link to the official copy. The list of brands comes from the FDA NDC Directory.

This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.

If someone may have taken too much, call Poison Help: 1‑800‑222‑1222. In an emergency, call 911.

Quick answers

What is Carboxymethylcellulose and glycerin used for?
The Drug Facts label of Refresh Tears Pf (Allergan, Inc.) lists these uses: For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun. May be used as a protectant against further irritation.
Do I need a prescription for Carboxymethylcellulose and glycerin?
No. The products on this page are sold without a prescription (over the counter).
Is a store brand the same as the name brand?
Products listed together below have the same active ingredients, in the same amount and the same form, as registered with the FDA. Inactive ingredients (such as colors, flavors and fillers) and package sizes can differ. Compare the “Active ingredient” box on both packages, and ask a pharmacist if you are not sure.
Has Carboxymethylcellulose and glycerin been recalled?
FDA enforcement reports list 1 recall of products on this page; the newest started December 30, 2020. A recall usually concerns specific products or lots, not every brand.

Drug Facts label

Every over-the-counter medicine must carry a “Drug Facts” box in the same order, set by FDA rules. Below is the label of one product for each common strength and form, quoted word for word. Your own package can differ (for example, children’s products have other directions): always follow the label on your package.

Refresh Tears Pf · Allergan, Inc.

Carboxymethylcellulose sodium 5 mg/mL · Glycerin 9 mg/mL, solution/ drops (ophthalmic)

Active ingredient

s Carboxymethylcellulose sodium 0.5% Glycerin 0.9%

Purpose

Eye lubricant Eye lubricant

Uses

For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun. May be used as a protectant against further irritation.

Warnings

For external use only. To avoid contamination, do not touch tip of container to any surface. Replace cap after using. If solution changes color or becomes cloudy , do not use.

Stop use and ask a doctor if

you experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours.

Keep out of reach of children

If swallowed, get medical help or contact a Poison Control Center right away.

Directions

Prior to first use, please read the “Instructions For Use” inside this carton. Instill 1 or 2 drops in the affected eye(s) as needed.

Other information

Use only if tape seals on top and bottom flaps are intact. Use before expiration date marked on container. Discard 90 days after opening. Store at 59°-77°F (15°-25°C). RETAIN THIS CARTON AND THE INSERT FOR FUTURE REFERENCE.

Inactive ingredients

Boric acid; calcium chloride dihydrate; erythritol; levocarnitine; magnesium chloride hexahydrate; potassium chloride; purified water; sodium borate decahydrate; and sodium citrate dihydrate.

Questions?

1.800. 6 78 . 1605 refresh eyedrops .com v3.0DFL3110

— FDA label of Refresh Tears Pf, Allergan, Inc., effective April 24, 2026. See the official label on DailyMed →

Equate Lubricant Eye Drops · Hanlim

Carboxymethylcellulose sodium 0.5% · Glycerin 0.9%, solution/ drops (ophthalmic)

Active ingredient

Carboxymethylcellulose sodium 0.5% Glycerin 0.9%

Purpose

Lubricant

Uses

  • for use as a protectant against further irritation or to relieve dryness of the eye.
  • for temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun.

Warnings

For external use only

Do not use

this product if

  • solution changes color or becomes cloudy

When using this product

  • do not touch lip of container to any surface to avoid contamination
  • replace cap after using
  • remove contact lenses before using

Stop use and ask a doctor if

you experience

  • eye pain
  • changes in vision
  • continued redness or irritation
  • condition worsens or persists for more than72hours

Keep out of reach of children

If swallowed, get medical help or contact a Poison Control Center (1-800-222-1222) right away.

Directions

Instill 1 to 2 drops in the affected eye(s) as needed.

Inactive ingredients

benzalkonium chloride, boric acid, calcium chloride hydrate (dihydrate) magnesium chloride, potassium chloride, sodium borate, sodium citrate hydrate, water for injection

— FDA label of Equate Lubricant Eye Drops, Hanlim, effective December 22, 2025. See the official label on DailyMed →

Refresh RELIEVA PF · Allergan, Inc.

Carboxymethylcellulose sodium 5 mg/mL · Glycerin 10 mg/mL, solution/ drops (ophthalmic)

Active ingredient

Carboxymethylcellulose sodium 0.5% Glycerin 1.0%

Purpose

Eye lubricant Eye lubricant

Uses

For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun. May be used as a protectant against further irritation.

Warnings

For external use only. To avoid contamination, do not touch tip of container to any surface. Do not reuse. Once opened, discard. Do not touch unit-dose tip to eye. If solution changes color or becomes cloudy , do not use.

Stop use and ask a doctor if

you experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours.

Keep out of reach of children

If swallowed, get medical help or contact a Poison Control Center right away.

Directions

To open, TWIST AND PULL TAB TO REMOVE. Instill 1 or 2 drops in the affected eye(s) as needed and discard container *Follow your eye doctor’s instructions if you are using this product after an eye surgery (e.g., LASIK) to relieve eye dryness and discomfort.

Other information

Use only if single-use container is intact. Use before expiration date marked on container. Store at 59°-77°F (15°-25°C). Protect from sunlight. RETAIN THIS CARTON FOR FUTURE REFERENCE.

Inactive ingredients

Calcium chloride dihydrate; erythritol; levocarnitine; magnesium chloride hexahydrate; potassium chloride; purified water; sodium lactate; and sodium hyaluronate. May contain hydrochloric acid and/or sodium hydroxide (to adjust pH).

Questions?

refresheyedrops.com v2.0DFL4515 Telephone icon and phone number

— FDA label of Refresh RELIEVA PF, Allergan, Inc., effective August 22, 2025. See the official label on DailyMed →

REFRESH OPTIVE Drops · Allergan, Inc.

Carboxymethylcellulose sodium 10 mg/mL · Glycerin 9 mg/mL, solution/ drops (ophthalmic)

Active ingredient

Carboxymethylcellulose sodium 1% Glycerin 0.9%

Purpose

Eye lubricant Eye lubricant

Uses

For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun. May be used as a protectant against further irritation.

Warnings

For external use only. To avoid contamination, do not touch tip of container to any surface. Replace cap after using. If solution changes color or becomes cloudy, do not use.

Stop use and ask a doctor if

you experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours.

Keep out of reach of children

If swallowed, get medical help or contact a Poison Control Center right away.

Directions

Instill 1 or 2 drops in the affected eye(s) as needed.

Other information

Use only if tape seals on top and bottom flaps are intact. Use before expiration date marked on container. Discard 90 days after opening. Store at 59°-77°F (15°-25°C). RETAIN THIS CARTON FOR FUTURE REFERENCE.

Inactive ingredients

Boric acid; calcium chloride dihydrate; erythritol; levocarnitine; magnesium chloride hexahydrate; potassium chloride; purified water; PURITE® (stabilized oxychloro complex); sodium borate decahydrate; and sodium citrate dihydrate.

Questions?

1.800.678.1605 r efresh eyedrops .com v2.0DFL5459

— FDA label of REFRESH OPTIVE Drops, Allergan, Inc., effective September 15, 2025. See the official label on DailyMed →

C-More Lubricant Eye Drops · Profound Nutrition Limited

Carboxymethylcellulose sodium, unspecified 0.3% · Glycerin 1%, solution/ drops (ophthalmic)

Active ingredient

Carboxymethylcellulose sodium 0.3% Glycerin 1%

Purpose

Lubricant

Uses

for use as a lubricant to prevent further irritation or to relieve dryness of the eye

Warnings

For external use only

Do not use

  • if solution changes color or becomes cloudy
  • for children under the age of 12

When using this product

  • to avoid contamination, do not touch tip of container to any surface
  • replace cap after using

Stop use and ask a doctor if

you experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours

Keep out of reach of children

If swallowed, get medical help or contact a Poison Control Center right away.

Directions

  • instill 1 or 2 drops in the affected eye(s) as needed
  • do not exceed 4 drops per eye daily unless directed by a physician
  • use the solution within one month after opening the container

Inactive ingredients

benzyl alcohol, boric acid, n-acetylcarnosine, potassium bicarbonate, water for injection

Questions?

+1-800-814-7385 You may also report serious side effects to this phone number.

— FDA label of C-More Lubricant Eye Drops, Profound Nutrition Limited, effective June 1, 2026. See the official label on DailyMed →

This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.

Same medicine, other brands

Each group lists the products that have exactly the same active ingredients, in the same amount and form, as registered with the FDA (NDC Directory). A store brand in the same group has the same medicine as the name brand; inactive ingredients, flavors and package sizes can differ. Each product links to its own official label.

Carboxymethylcellulose sodium 5 mg/mL · Glycerin 9 mg/mL · solution/ drops (ophthalmic) · 8 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Medics Choice Fresh and Soothe KC Pharmaceuticals, Inc. DailyMed
Medics Choice Fresh and Soothe Unimed DailyMed
Refresh Optive Allergan, Inc. DailyMed
Refresh Relieva Allergan, Inc. DailyMed
Refresh Relieva PF Xtra Allergan, Inc. DailyMed
Refresh Relieva Preservative Free Allergan, Inc. DailyMed
Refresh Tears Pf Allergan, Inc. DailyMed
Carboxymethylcellulose sodium 0.5% · Glycerin 0.9% · solution/ drops (ophthalmic) · 3 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Equate Lubricant Eye Drops Hanlim DailyMed
Equate Lubricant Eye Drops Walmart DailyMed
Equate Optimal Hydration Lubricant Eye Drops Walmart, Inc. DailyMed
Carboxymethylcellulose sodium 5 mg/mL · Glycerin 10 mg/mL · solution/ drops (ophthalmic) · 2 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Refresh RELIEVA PF Allergan, Inc. DailyMed
Carboxymethylcellulose sodium 5 mg/mL · Glycerin 3 mg/mL · solution (ophthalmic) · 2 products
Brand or product nameCompany on the labelLabel
VitaPhyte Lubricant Eye Drops Guangzhou Liyan Cosmetics Technology Co., Ltd. —
VitaPhyte Lubricating Eye Drops Guangzhou Liyan Cosmetics Technology Co., Ltd. —
Carboxymethylcellulose sodium 10 mg/mL · Glycerin 9 mg/mL · solution/ drops (ophthalmic) · 1 product

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
REFRESH OPTIVE Drops Allergan, Inc. DailyMed
Carboxymethylcellulose sodium, unspecified 0.3% · Glycerin 1% · solution/ drops (ophthalmic) · 1 product

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
C-More Lubricant Eye Drops Profound Nutrition Limited DailyMed

What pharmacies pay (NADAC)

The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.

This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.

NADAC per unit for Carboxymethylcellulose and glycerin, by strength and form
Strength and formGeneric or brandPharmacies pay
carboxymethylcellulose sodium 10 mg/mL · glycerin 9 mg/mL
solution/ drops
Brand: REFRESH OPTIVE Drops $1.10 per mL
carboxymethylcellulose sodium 5 mg/mL · glycerin 10 mg/mL
solution/ drops
Brand: Refresh RELIEVA PF $0.4530 per unit
carboxymethylcellulose sodium 5 mg/mL · glycerin 9 mg/mL
solution/ drops
Brand: Refresh Optive $0.3415 per unit
carboxymethylcellulose sodium 5 mg/mL · glycerin 9 mg/mL
solution/ drops
Brand: Refresh Optive $0.6590 per mL
carboxymethylcellulose sodium 5 mg/mL · glycerin 9 mg/mL
solution/ drops
Brand: Refresh Relieva $1.09 per mL
carboxymethylcellulose sodium 5 mg/mL · glycerin 9 mg/mL
solution/ drops
Brand: Refresh Relieva PF Xtra $1.25 per mL
carboxymethylcellulose sodium 5 mg/mL · glycerin 9 mg/mL
solution/ drops
Brand: Refresh Relieva Preservative Free $1.25 per mL
carboxymethylcellulose sodium 5 mg/mL · glycerin 9 mg/mL
solution/ drops
Brand: Refresh Tears Pf $1.25 per mL

NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.

Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →

Companies that sell this medicine

The company named on the package (maker or distributor), as listed in the FDA NDC Directory, with its number of over-the-counter products of this medicine.

  • Allergan, Inc.9 products
  • Guangzhou Liyan Cosmetics Technology Co., Ltd.2 products
  • Walmart1 product
  • Unimed1 product
  • Hanlim1 product
  • KC Pharmaceuticals, Inc.1 product
  • Walmart, Inc.1 product
  • Profound Nutrition Limited1 product

Recalls

From FDA enforcement reports, matched by the product’s NDC code or label. A recall usually covers specific products or lots: check the name and lot number on your package.

  1. December 30, 2020 · Class II · Terminated · D-0233-2021

    Labeling: Missing instructions for use insert

    Refresh Relieva PF Preservative-Free Lubricant Eye Drops 0.33 fl oz (10 mL) Sterile Distributed by: Allergan, an AbbVie company Madison, NJ 07940 UPC 3 00236 63410 0, NDC 0023-6634-10. — Allergan, PLC.

Next steps

Sources

  1. Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  2. NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  3. Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
  4. FDA rule for the Drug Facts label (21 CFR 201.66)

Only medicines marketed under FDA rules for nonprescription drugs (an FDA monograph or an FDA approval) are listed. Homeopathic products are not listed: the FDA does not evaluate them for safety or effectiveness.

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