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Over-the-counter medicine · no prescription needed

Bacitracin zinc, neomycin sulfate, polymyxin b sulfate and pramoxine hydrochloride

Purpose on the label: First aid antibiotic External analgesic

Pain relief on the skin

Official FDA data, not advice

The label text is quoted exactly as the company filed it with the U.S. Food and Drug Administration (FDA), with a link to the official copy. The list of brands comes from the FDA NDC Directory.

This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.

If someone may have taken too much, call Poison Help: 1‑800‑222‑1222. In an emergency, call 911.

Quick answers

What is Bacitracin zinc, neomycin sulfate, polymyxin b sulfate and pramoxine hydrochloride used for?
The Drug Facts label of First Aid Antibiotic and Burn Relief (Amazon.com Services LLC) lists these uses: first aid to help prevent infection and for the temporary relief of pain or discomfort in minor; cuts; scrapes; burns.
Do I need a prescription for Bacitracin zinc, neomycin sulfate, polymyxin b sulfate and pramoxine hydrochloride?
No. The products on this page are sold without a prescription (over the counter).
Is a store brand the same as the name brand?
Products listed together below have the same active ingredients, in the same amount and the same form, as registered with the FDA. Inactive ingredients (such as colors, flavors and fillers) and package sizes can differ. Compare the “Active ingredient” box on both packages, and ask a pharmacist if you are not sure.
Has Bacitracin zinc, neomycin sulfate, polymyxin b sulfate and pramoxine hydrochloride been recalled?
No recall linked to these products appears in the FDA enforcement reports we use.

Drug Facts label

Every over-the-counter medicine must carry a “Drug Facts” box in the same order, set by FDA rules. Below is the label of one product for each common strength and form, quoted word for word. Your own package can differ (for example, children’s products have other directions): always follow the label on your package.

First Aid Antibiotic and Burn Relief · Amazon.com Services LLC

Bacitracin zinc 500 [USP'U]/g · Neomycin sulfate 0.35% · Polymyxin b sulfate 10000 [USP'U]/g · Pramoxine hydrochloride 1%, ointment (topical)

Active ingredient (in each gram)

Bacitracin zinc 500 units Neomycin sulfate equivalent to 3.5 mg of neomycin base Polymyxin B 10,000 units as polymyxin B sulfate Pramoxine HCl 10 mg

Purpose

First aid antibiotic External analgesic

Uses

first aid to help prevent infection and for the temporary relief of pain or discomfort in minor:

  • cuts
  • scrapes
  • burns

Warnings

For external use only

Do not use

  • if you are allergic to any of the ingredients
  • in the eyes
  • over large areas of the body

Ask a doctor before use if

you have

  • deep or puncture wounds
  • animal bites
  • serious burns

Stop use and ask a doctor if

  • you need to use longer than 1 week
  • condition persists or gets worse
  • symptoms persist for more than 1 week, or clear up and occur again within a few days
  • rash or other allergic reaction develops

Keep out of reach of children

If swallowed, get medical help or contact a Poison Control Center right away (1-800-222-1222).

Directions

  • adults and children 2 years of age or older:
  • clean the affected area
  • apply a small amount of this product (an amount equal to the surface area of the tip of a finger) on the area 1 to 3 times daily
  • may be covered with a sterile bandage
  • children under 2 years of age: ask a doctor

Other information

  • store at 20-25°C (68-77°F)

Inactive ingredients

white petrolatum

Questions?

1-800-719-9260

— FDA label of First Aid Antibiotic and Burn Relief, Amazon.com Services LLC, effective August 18, 2026. See the official label on DailyMed →

Natureplex Antibiotic plus Pain · Natureplex, LLC

Bacitracin zinc 500 [iU]/g · Neomycin sulfate 0.35% · Polymyxin b sulfate 10000 [iU]/g · Pramoxine hydrochloride 1%, ointment (topical)

Active ingredient (in each gram)

Purpose Bacitracin zinc 500 units First aid antibiotic Neomycin sulfate 3.5 mg First aid antibiotic Polymyxin B sulfate 10,000 units First aid antibiotic Pramoxine hydrochloride 10 mg External analgesic

Purpose

Active ingredients (in each gram) Purpose Bacitracin zinc 500 units First aid antibiotic Neomycin sulfate 3.5 mg First aid antibiotic Polymyxin B sulfate 10,000 units First aid antibiotic Pramoxine hydrochloride 10 mg External analgesic

Uses

First aid to help prevent infection and temporary relief of pain or discomfort in minor: cuts scrapes burns

Warnings

For external use only. Not for prolonged use.

Do not use

in the eyes, nose, or over large areas of the body if you are allergic to any of the ingredients longer than 1 week unless directed by a doctor

Ask a doctor before use if

you have deep or puncture wounds animal bites serious burns

Stop use and ask a doctor if

condition persists for more than 7 days, gets worse, or clears up and occurs again within a few days a rash, redness, irritation, swelling, or pain persists or increases, or other allergic reaction develops

If pregnant or breast-feeding

ask a health professional before use.

Keep out of reach of children

If swallowed, get medical help or contact a Poison Control Center right away: 800-222-1222.

Directions

Adults and children 2 years of age and older: clean the affected area apply a small amount of this product (an amount equal to the surface area of the tip of a finger) on the area 1 to 3 times daily the affected area may be covered with a sterile bandage Children under 2 years of age: consult a doctor

Inactive ingredients

petrolatum

Questions?

866-323-0107 or www.natureplex.com

— FDA label of Natureplex Antibiotic plus Pain, Natureplex, LLC, effective January 29, 2026. See the official label on DailyMed →

Penimixcina · Opmx LLC

Bacitracin zinc 500 [iU]/g · Neomycin sulfate 0.5% · Polymyxin b sulfate 5000 [iU]/g · Pramoxine hydrochloride 1%, ointment (topical)

Active ingredient (IN EACH GRAM)

BACITRACIN ZINC 500 UNITS NEOMYCIN SULFATE 5 MG (EQUIVALENT TO 3.5 MG NEOMYCIN) POLYMYXIN B SULFATE 5000 UNITS PRAMOXINE HYCHLORIDE 10 MG

Purpose

FIRST AID ANTIBIOTIC PAIN RELIEVER

Uses

FIRST AID TO HELP PREVENT INFECTION IN MINOR CUTS SCRAPES BURNS

Warnings

For external use only. DO NOT USE IN THE EYES IF YOU ARE ALLERGIC TO ANY OF THE INGREDIENTS OVER LARGE AREAS OF THE BODY LONGER THAN 1 WEEK UNLESS DIRECTED BY A DOCTOR ASK A DOCTOR BEFORE USE IN CASE OF DEEP OR PUNCTURE WOUNDS ANIMAL BITES OR SERIOUS BURNS STOP USE AND ASK A DOCTOR IF The condition persists or gets worse A rash or other allergic reaction develops

Keep out of reach of children

If swallowed get medical help or contact Poison Control Center right away.

Directions

CLEAN THE AFFECTED AREA APPLY A SMALL AMOUNT OF THIS PRODUCT (AN AMOUNT EQUAL TO THE SURFACE AREA OF THE TIP OF A FINGER) ON THE AREA 1 TO 3 TIMES DAILY MAY BE COVERED WITH A STERILE BANDAGE

Other information

STORE AT 15° - 30°C (59°F - 86°F) AVOID EXCESSIVE HEAT AND HUMIDITY

Inactive ingredients

WHITE PETROLATUM

— FDA label of Penimixcina, Opmx LLC, effective May 17, 2024. See the official label on DailyMed →

Natureplex Antibiotic Plus Pain, Itch, Scar Relief · Natureplex LLC

Bacitracin zinc 500 [iU]/g · Neomycin sulfate 0.35% · Polymyxin b sulfate 10000 [iU]/g · Pramoxine hydrochloride 1%, cream (topical)

Active ingredient (in each gram)

Purpose Bacitracin zinc 500 units First aid antibiotic Neomycin sulfate 3.5 mg First aid antibiotic Polymyxin B sulfate 10,000 units First aid antibiotic Pramoxine hydrochloride 10 mg External analgesic

Purpose

Active ingredients (in each gram) Purpose Bacitracin zinc 500 units First aid antibiotic Neomycin sulfate 3.5 mg First aid antibiotic Polymyxin B sulfate 10,000 units First aid antibiotic Pramoxine hydrochloride 10 mg External analgesic

Uses

First aid to help prevent infection and temporary relief of pain or discomfort in minor: cuts scrapes burns

Warnings

For external use only. Not for prolonged use.

Do not use

in the eyes, nose, or over large areas of the body if you are allergic to any of the ingredients longer than 1 week unless directed by a doctor

Ask a doctor before use if

you have deep or puncture wounds animal bites serious burns

Stop use and ask a doctor if

condition persists for more than 7 days, gets worse, or clears up and occurs again within a few days a rash, redness, irritation, swelling, or pain persists or increases, or other allergic reaction develops

If pregnant or breast-feeding

ask a health professional before use.

Keep out of reach of children

If swallowed, get medical help or contact a Poison Control Center right away: 800-222-1222.

Directions

Adults and children 2 years old and older: clean the affected area apply a small amount of this product (an amount equal to the surface area of the tip of a finger) on the area 1 to 3 times daily the affected area may be covered with a sterile bandage Children under 2 years old: ask a doctor

Inactive ingredients

gossypium herbaceum (cotton) seed oil, olea europaea (olive) fruit oil, petrolatum, sodium pyruvate, theobroma cacao (cocoa) seed butter, tocopheryl (vitamin E) acetate

Questions?

866-323-0107 or www.natureplex.com

— FDA label of Natureplex Antibiotic Plus Pain, Itch, Scar Relief, Natureplex LLC, effective August 15, 2025. See the official label on DailyMed →

Drs. Pharmacy Triple Antibiotic Plus Pain relief · OL PHARMA TECH, LLC Drs PHARMACY

Bacitracin zinc 500 [USP'U]/1000 mg · Neomycin sulfate 3.5 mg/1000 mg · Polymyxin b sulfate 10000 [USP'U]/1000 mg · Pramoxine hydrochloride 10 mg/1000 mg, ointment (topical)

Active ingredient

Bacitracin zinc 500 units Neomycin 3.5 mg Polymyxin B sulfate 10,000 units Pramoxine hydrochloride 10 mg

Purpose

first aid antibiotic External Analgesic

Uses

first aid to help prevent infection in minor

  • cuts
  • scrapes
  • burns

Warnings

For external use only Do Not Use

Do not use

  • if you are allergic to any of the ingredients
  • in the eyes
  • over large areas of the body
  • longer than 1 week unless directed by a doctor

Ask a doctor before use if

you have

  • deep or puncture wounds
  • animal bites
  • serious burns

Stop use and ask a doctor if

  • the condition persists or gets worse
  • a rash or other allergic reaction develops KEEP OUT OF REACH OF CHILDREN If swallowed, get medical help or contact a Poison Control Center right away.

Directions

  • clean the affected area
  • apply a small amount of this product (an amount equal to the surface area of the tip of a finger) on the area 1 to 3 times daily
  • may be covered with a sterile bandage

Other information

Store at room temperature

Inactive ingredients

Petrolatum

Questions?

www.drspharmacyusa.com

— FDA label of Drs. Pharmacy Triple Antibiotic Plus Pain relief, OL PHARMA TECH, LLC Drs PHARMACY, effective July 9, 2026. See the official label on DailyMed →

Drs. Pharmacy Triple Antibiotic Plus · OL PHARMA TECH, LLC Drs PHARMACY

Bacitracin zinc 400 [USP'U]/1000 mg · Neomycin sulfate 3.5 mg/1000 mg · Polymyxin b sulfate 5000 [USP'U]/1000 mg · Pramoxine hydrochloride 10 mg/1000 mg, ointment (topical)

Active ingredient

Bacitracin zinc 400 units Neomycin 3.5 mg Polymyxin B sulfate 5,000 units Pramoxine hydrochloride 10 mg

Purpose

first aid antibiotic External Analgesic

Uses

first aid to help prevent infection in minor

  • cuts
  • scrapes
  • burns

Warnings

For external use only Do Not Use

Do not use

  • if you are allergic to any of the ingredients
  • in the eyes
  • over large areas of the body
  • longer than 1 week unless directed by a doctor

Ask a doctor before use if

you have

  • deep or puncture wounds
  • animal bites
  • serious burns

Stop use and ask a doctor if

  • the condition persists or gets worse
  • a rash or other allergic reaction develops KEEP OUT OF REACH OF CHILDREN If swallowed, get medical help or contact a Poison Control Center right away.

Directions

  • clean the affected area
  • apply a small amount of this product (an amount equal to the surface area of the tip of a finger) on the area 1 to 3 times daily
  • may be covered with a sterile bandage

Other information

Store at room temperature

Inactive ingredients

Petrolatum

Questions?

www.drspharmacyusa.com

— FDA label of Drs. Pharmacy Triple Antibiotic Plus, OL PHARMA TECH, LLC Drs PHARMACY, effective January 9, 2025. See the official label on DailyMed →

This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.

Same medicine, other brands

Each group lists the products that have exactly the same active ingredients, in the same amount and form, as registered with the FDA (NDC Directory). A store brand in the same group has the same medicine as the name brand; inactive ingredients, flavors and package sizes can differ. Each product links to its own official label.

Bacitracin zinc 500 [USP'U]/g · Neomycin sulfate 0.35% · Polymyxin b sulfate 10000 [USP'U]/g · Pramoxine hydrochloride 1% · ointment (topical) · 50 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Antibiotic, Pain and Scar CVS Pharmacy DailyMed
AVON HeXashield Triple Antibiotic with Pain Relief Tai Guk Pharm. Co., Ltd. DailyMed
Basic Care First Aid Antibiotic Amazon.com Services LLC DailyMed
Basic Care First Aid Antibiotic and Burn Relief Amazon.com Services LLC DailyMed
CareALL Triple Antibiotic plus Pain Relief New World Imports, Inc DailyMed
Careone Triple Antibiotic American Sales Company DailyMed
Caring Mill Triple Antibiotic and Pain FSA Store Inc. (Caring Mills) DailyMed
Curad Maximum Strength Triple Antibiotic Medline Industries, LP DailyMed
DG Health Antibiotic Dolgencorp, LLC DailyMed
Dg Health Triple Antibiotic Dolgencorp, LLC DailyMed
Drs pharmacy triple antibiotic Pain plus itch plus Scar Ol Pharma Tech, LLC DailyMed
Exchange Select First Aid Triple Anitbiotic Pain Relieving Army & Air Force Exchange Service DailyMed
Family Wellness Pain Scar Itch Trifecta Pharmaceutical USA LLC DailyMed
First Aid Antibiotic Walgreen Company DailyMed
First Aid Antibiotic and Burn Relief Amazon.com Services LLC DailyMed
First Aid Antibiotic plus Burn Relief Trifecta Pharmaceuticals USA LLC DailyMed
Good Sense Triple Antibiotic L. Perrigo Company DailyMed
Good Sense Triple Antibiotic and Pain Relief L. Perrigo Company DailyMed
Harris Teeter Triple Antibiotic and Pain Relief Harris Teeter LLC DailyMed
Leader Triple antibiotic and pain relief Cardinal Health 110 dba LEADER DailyMed
Multi Action Trifecta Pharmaceutical USA LLC DailyMed
Multi-Action Antibiotic and Pain Relief Target Corporation DailyMed
Neosporin Plus Pain Relief Kenvue Brands LLC DailyMed
Sheffield Triple Antibiotic Plus Pain Relief Sheffield Pharmaceuticals LLC DailyMed
Signature Care Triple Antibiotic Safeway DailyMed

Showing 25 of 47 brands.

Bacitracin zinc 500 [iU]/g · Neomycin sulfate 0.35% · Polymyxin b sulfate 10000 [iU]/g · Pramoxine hydrochloride 1% · ointment (topical) · 10 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Cuadriderma ProMex LLC DailyMed
Good Neighbor Pharmacy Triple Antibiotic Plus Pain Relief Amerisource Bergen —
Live Better Triple Antibiotic plus Pain Relief The Great Atlantic & Pacific Tea Company DailyMed
Natureplex Antibiotic plus Pain Natureplex, LLC DailyMed
Neosporin Pain Itch Scar Kenvue Brands LLC DailyMed
NEOSPORIN Plus BURN RELIEF Kenvue Brands LLC DailyMed
Shopko Triple Antibiotic plus Pain Relief Shopko Stores Operating Co., LLC DailyMed
Sunmark Triple Antibiotic Plus Pain Relief A-S Medication Solutions DailyMed
Sunmark Triple Antibiotic Plus Pain Relief Strategic Sourcing Services LLC DailyMed
TopCare Triple Antibiotic Plus Pain Relief Topco Associates LLC DailyMed
Bacitracin zinc 500 [iU]/g · Neomycin sulfate 0.5% · Polymyxin b sulfate 5000 [iU]/g · Pramoxine hydrochloride 1% · ointment (topical) · 3 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Penimixcina Opmx LLC DailyMed
Pentrexcilina Triple Antibiotic Plus Pain Relief Opmx LLC DailyMed
Triple Antibiotic with Pain Relief Safetec of America, Inc. DailyMed
Bacitracin zinc 500 [iU]/g · Neomycin sulfate 0.35% · Polymyxin b sulfate 10000 [iU]/g · Pramoxine hydrochloride 1% · cream (topical) · 2 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Equate Antibiotic Plus Pain, Itch, Scar Relief WalMart DailyMed
Natureplex Antibiotic Plus Pain, Itch, Scar Relief Natureplex LLC DailyMed
Bacitracin zinc 500 [USP'U]/1000 mg · Neomycin sulfate 3.5 mg/1000 mg · Polymyxin b sulfate 10000 [USP'U]/1000 mg · Pramoxine hydrochloride 10 mg/1000 mg · ointment (topical) · 2 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Drs. Pharmacy Triple Antibiotic AND BURN RELIEF OL PHARMA TECH, LLC Drs PHARMACY DailyMed
Drs. Pharmacy Triple Antibiotic Plus Pain relief OL PHARMA TECH, LLC Drs PHARMACY DailyMed
Bacitracin zinc 400 [USP'U]/1000 mg · Neomycin sulfate 3.5 mg/1000 mg · Polymyxin b sulfate 5000 [USP'U]/1000 mg · Pramoxine hydrochloride 10 mg/1000 mg · ointment (topical) · 1 product

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Drs. Pharmacy Triple Antibiotic Plus OL PHARMA TECH, LLC Drs PHARMACY DailyMed
Bacitracin zinc 500 [USP'U]/g · Neomycin sulfate 0.35% · Polymyxin b sulfate 10000 [USP'U]/g · Pramoxine hydrochloride 1% · cream (topical) · 1 product
Brand or product nameCompany on the labelLabel
Equate First Aid Antibiotic Plus Pain Relief WalMart DailyMed
Bacitracin zinc 0.51% · Neomycin sulfate 0.0035% · Polymyxin b sulfate 1% · Pramoxine hydrochloride 0.01% · ointment (topical) · 1 product
Brand or product nameCompany on the labelLabel
Family Wellness Antiseptic and Pain Relief Front Pharmaceutical PLC DailyMed
Bacitracin zinc 400 [USP'U]/g · Neomycin sulfate 0.5% · Polymyxin b sulfate 10000 [USP'U]/g · Pramoxine hydrochloride 1% · ointment (topical) · 1 product
Brand or product nameCompany on the labelLabel
Triple Antibiotic Plus Pain Relief Bi-Mart DailyMed
Bacitracin zinc 500 [USP'U]/100 g · Neomycin sulfate 3.5 mg/100 g · Polymyxin b sulfate 10000 [USP'U]/100 g · Pramoxine hydrochloride 10 mg/100 g · ointment (topical) · 1 product
Brand or product nameCompany on the labelLabel
Triple Antibiotic and Pain Relief Trifecta Pharmaceutical USA LLC DailyMed

What pharmacies pay (NADAC)

The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.

This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.

NADAC per unit for Bacitracin zinc, neomycin sulfate, polymyxin b sulfate and pramoxine hydrochloride, by strength and form
Strength and formGeneric or brandPharmacies pay
bacitracin zinc 500 USP units/g · neomycin sulfate 0.35% · polymyxin b sulfate 10000 USP units/g · pramoxine hydrochloride 1%
ointment
Generic $0.1243 per gram
bacitracin zinc 500 units/g · neomycin sulfate 0.35% · polymyxin b sulfate 10000 units/g · pramoxine hydrochloride 1%
ointment
Generic $0.1243 per gram

NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.

Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →

Companies that sell this medicine

The company named on the package (maker or distributor), as listed in the FDA NDC Directory, with its number of over-the-counter products of this medicine.

  • Amazon.com Services LLC3 products
  • OL PHARMA TECH, LLC Drs PHARMACY3 products
  • Kenvue Brands LLC3 products
  • CVS Pharmacy3 products
  • Walgreen Company3 products
  • Trifecta Pharmaceutical USA LLC3 products
  • Meijer Distribution Inc2 products
  • H E B2 products
  • Natureplex, LLC2 products
  • Target Corporation2 products
  • Strategic Sourcing Services LLC2 products
  • WalMart2 products
  • Chain Drug Marketing Association Inc.2 products
  • Safeway2 products
  • L. Perrigo Company2 products
  • Topco Associates LLC2 products
  • Dolgencorp, LLC2 products
  • Opmx LLC2 products
  • New World Imports, Inc2 products
  • Kroger Company1 product
  • Harris Teeter LLC1 product
  • A-S Medication Solutions1 product
  • Publix Super Markets Inc1 product
  • Sheffield Pharmaceuticals LLC1 product
  • Encube Ethicals, Inc.1 product
  • Front Pharmaceutical PLC1 product
  • Tai Guk Pharm. Co., Ltd.1 product
  • The Great Atlantic & Pacific Tea Company1 product
  • Veridian Healthcare1 product
  • FSA Store Inc. (Caring Mills)1 product

Showing the 30 companies with the most products, of 47.

Recalls

No recall linked to these products (by their NDC code or label) appears in the FDA enforcement reports.

Sources

  1. Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  2. NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  3. Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
  4. FDA rule for the Drug Facts label (21 CFR 201.66)

Only medicines marketed under FDA rules for nonprescription drugs (an FDA monograph or an FDA approval) are listed. Homeopathic products are not listed: the FDA does not evaluate them for safety or effectiveness.

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