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Over-the-counter medicine · no prescription needed

Acetaminophen, dextromethorphan, guaifenesin and phenylephrine

Cough, cold and flu

Official FDA data, not advice

The label text is quoted exactly as the company filed it with the U.S. Food and Drug Administration (FDA), with a link to the official copy. The list of brands comes from the FDA NDC Directory.

This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.

If someone may have taken too much, call Poison Help: 1‑800‑222‑1222. In an emergency, call 911.

Quick answers

What is Acetaminophen, dextromethorphan, guaifenesin and phenylephrine used for?
The Drug Facts label of Tylenol Cold Plus Flu Severe (Savings Distributors LLC) lists these uses: for the temporary relief of the following cold/flu symptoms; minor aches and pains; headache; sore throat; nasal congestion; cough; helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive; temporarily reduces fever.
Do I need a prescription for Acetaminophen, dextromethorphan, guaifenesin and phenylephrine?
No. The products on this page are sold without a prescription (over the counter).
Is a store brand the same as the name brand?
Products listed together below have the same active ingredients, in the same amount and the same form, as registered with the FDA. Inactive ingredients (such as colors, flavors and fillers) and package sizes can differ. Compare the “Active ingredient” box on both packages, and ask a pharmacist if you are not sure.
Has Acetaminophen, dextromethorphan, guaifenesin and phenylephrine been recalled?
FDA enforcement reports list 3 recalls of products on this page; the newest started October 11, 2022. A recall usually concerns specific products or lots, not every brand.

Drug Facts label

Every over-the-counter medicine must carry a “Drug Facts” box in the same order, set by FDA rules. Below is the label of one product for each common strength and form, quoted word for word. Your own package can differ (for example, children’s products have other directions): always follow the label on your package.

Tylenol Cold Plus Flu Severe · Savings Distributors LLC

Acetaminophen 325 mg · Dextromethorphan hydrobromide 10 mg · Guaifenesin 200 mg · Phenylephrine hydrochloride 5 mg, tablet, film coated (oral)

Active ingredient (in each caplet)

Acetaminophen 325 mg Dextromethorphan HBr 10 mg Guaifenesin 200 mg Phenylephrine HCl 5 mg Purpose Pain reliever/fever reducer Cough suppressant Expectorant Nasal decongestant

Purpose

Pain reliever/fever reducer Cough suppressant Expectorant Nasal decongestant

Uses

  • for the temporary relief of the following cold/flu symptoms:
  • minor aches and pains
  • headache
  • sore throat
  • nasal congestion
  • cough
  • helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive
  • temporarily reduces fever

Warnings

  • Liver warning: This product contains acetaminophen. The maximum daily dose of this product is 10 caplets (3,250 mg acetaminophen) in 24 hours. Severe liver damage may occur if you take
  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product
  • Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:
  • skin reddening
  • blisters
  • rash If a skin reaction occurs, stop use and seek medical help right away.
  • Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
  • if you have ever had an allergic reaction to this product or any of its ingredients.

Ask a doctor before use if

you have

  • liver disease
  • heart disease
  • high blood pressure
  • thyroid disease
  • diabetes
  • trouble urinating due to an enlarged prostate gland
  • persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis or emphysema
  • cough that occurs with too much phlegm (mucus)

Ask a doctor or pharmacist before use if

you are taking the blood thinning drug warfarin

When using this product

do not exceed recommended dose

Stop use and ask a doctor if

  • nervousness, dizziness, or sleeplessness occur
  • pain, nasal congestion or cough gets worse or lasts more than 7 days
  • fever gets worse or lasts more than 3 days
  • redness or swelling is present
  • new symptoms occur
  • cough comes back or occurs with rash or headache that lasts These could be signs of a serious condition.

If pregnant or breast-feeding

ask a health professional before use.

Keep out of reach of children

  • Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Directions

  • do not take more than directed (see overdose warning) adults and children 12 years and over
  • take 2 caplets every 4 hours
  • swallow whole; do not crush, chew or dissolve
  • do not take more than 10 caplets in 24 hours children under 12 years ask a doctor

Inactive ingredients

carnauba wax, croscarmellose sodium, D&C yellow no. 10 aluminum lake, flavor, hydroxypropyl cellulose, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, pregelatinized starch, sucralose, titanium dioxide

Questions?

call 1-877-895-3665 (toll-free) or 215-273-8755 (collect)

— FDA label of Tylenol Cold Plus Flu Severe, Savings Distributors LLC, effective May 1, 2026. See the official label on DailyMed →

Severe Cold and Flu · Hyvee Inc

Acetaminophen 325 mg · Dextromethorphan hydrobromide 10 mg · Guaifenesin 200 mg · Phenylephrine hydrochloride 5 mg, tablet, coated (oral)

Active ingredient (in each caplet)

Purpose Acetaminophen 325 mg Pain reliever/fever reducer Dextromethorphan HBr 10 mg Cough suppressant Guaifenesin 200 mg Expectorant Phenylephrine HCl 5 mg Nasal decongestant

Purpose

Active ingredients (in each caplet) Purpose Acetaminophen 325 mg Pain reliever/fever reducer Dextromethorphan HBr 10 mg Cough suppressant Guaifenesin 200 mg Expectorant Phenylephrine HCl 5 mg Nasal decongestant

Uses

temporarily relieves common cold/flu symptoms: nasal congestion sinus congestion and pressure cough due to minor throat & bronchial irritation minor aches and pains headache fever sore throat reduces swelling of nasal passages temporarily restores freer breathing through the nose promotes nasal and/or sinus drainage helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive

Warnings

Liver warning This product contains acetaminophen. Severe liver damage may occur if you take more than 8 caplets in 24 hours, which is the maximum daily amount with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy alert Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening blisters rash If a skin reaction occurs, stop use and seek medical help right away. Sore throat warning If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.

Do not use

with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.

Ask a doctor before use if

you have liver disease heart disease high blood pressure thyroid disease diabetes trouble urinating due to an enlarged prostate gland cough that occurs with too much phlegm (mucus) persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema

Ask a doctor or pharmacist before use if

you are taking the blood thinning drug warfarin

When using this product

do not use more than directed.

Stop use and ask a doctor if

you get nervous, dizzy, or sleepless pain, nasal congestion, or cough gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur cough comes back or occurs with rash or headache that lasts These could be signs of a serious condition.

If pregnant or breast-feeding

ask a health professional before use.

Keep out of reach of children

Overdose warning Taking more than directed can cause serious health problems. In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Directions

take only as directed (see overdose warning ) do not exceed 4 doses per 24 hours

adults and children 12 years and overtake 2 caplets every 4 hours
children 4 to under 12 yearsask a doctor
children under 4 yearsdo not use

Inactive ingredients

colloidal silicon dioxide, corn starch, croscarmellose sodium, crospovidone, FD&C red #40 aluminum lake, FD&C yellow #6 aluminum lake, magnesium stearate, maltodextrin, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone, pregelatinized starch, stearic acid, talc, titanium dioxide

Questions?

1-844-705-4384

— FDA label of Severe Cold and Flu, Hyvee Inc, effective January 13, 2026. See the official label on DailyMed →

Topcare Day Time Cold and Flu · Topco Associates LLC

Acetaminophen 325 mg/15 mL · Dextromethorphan hydrobromide 10 mg/15 mL · Guaifenesin 200 mg/15 mL · Phenylephrine hydrochloride 5 mg/15 mL, solution (oral)

Active ingredient (in each 15 mL)

Acetaminophen 325 mg Dextromethorphan HBr 10 mg Guaifenesin 200 mg Phenylephrine HCl 5 mg

Purpose

Pain reliever/fever reducer Cough suppressant Expectorant Nasal decongestant

Uses

temporarily relieves common cold/flu symptoms:

  • sinus congestion and pressure
  • nasal congestion
  • minor aches and pains
  • headache
  • sore throat
  • fever
  • cough due to minor throat and bronchial irritation
  • reduces swelling of nasal passages
  • promotes nasal and/or sinus drainage
  • temporarily restores freer breathing through the nose
  • helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive

Warnings

  • Liver warning: This product contains acetaminophen. Severe liver damage may occur if
  • adult takes more than 4,000 mg of acetaminophen in 24 hours
  • child takes more than 5 doses in 24 hours
  • taken with other drugs containing acetaminophen
  • adult has 3 or more alcoholic drinks every day while using this product
  • Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include:
  • skin reddening
  • blisters
  • rash If a skin reaction occurs, stop use and seek medical help right away.
  • Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
  • if you have ever had an allergic reaction to this product or any of its ingredients

Ask a doctor before use if

you have

  • liver disease
  • heart disease
  • high blood pressure
  • thyroid disease
  • diabetes
  • cough that occurs with too much phlegm (mucus)
  • trouble urinating due to an enlarged prostate gland
  • persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema

Ask a doctor or pharmacist before use if

you are taking the blood thinning drug warfarin

When using this product

do not use more than directed

Stop use and ask a doctor if

  • you get nervous, dizzy or sleepless
  • pain, nasal congestion, or cough gets worse or lasts more than 5 days (children) or 7 days (adults)
  • fever gets worse or lasts more than 3 days
  • redness or swelling is present
  • new symptoms occur
  • cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition.

If pregnant or breast-feeding

ask a health professional before use.

Keep out of reach of children

  • Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Directions

take only as directed – see Overdose warning

  • only use the dose cup provided
  • do not exceed 4 doses per 24 hrs
adults & children 12 yrs & over 30 mL every 4 hrs
children 6 to under 12 yrs 15 mL every 4 hrs
children 4 to under 6 yrs ask a doctor
children under 4 yrs do not use

Inactive ingredients

anhydrous citric acid, FD&C yellow #6, flavor, glycerin, menthol, polyethylene glycol, propylene glycol, purified water, saccharin sodium, sodium benzoate, sodium chloride, sodium citrate, sorbitol solution, sucralose, xanthan gum

Questions?

1-888-423-0139

— FDA label of Topcare Day Time Cold and Flu, Topco Associates LLC, effective May 14, 2026. See the official label on DailyMed →

TopCare Day Time SEVERE Cold and Flu · Topco Associates LLC

Acetaminophen 325 mg · Dextromethorphan hydrobromide 10 mg · Guaifenesin 200 mg · Phenylephrine hydrochloride 5 mg, capsule, liquid filled (oral)

Active ingredient (in each softgel)

Acetaminophen 325 mg Dextromethorphan HBr 10 mg Guaifenesin 200 mg Phenylephrine HCl 5 mg

Purpose

Pain reliever/fever reducer Cough suppressant Expectorant Nasal decongestant

Uses

  • temporarily relieves common cold/flu symptoms:
  • nasal congestion
  • sinus congestion & pressure
  • cough due to minor throat & bronchial irritation
  • minor aches & pains
  • headache
  • fever
  • sore throat
  • reduces swelling of nasal passages
  • temporarily restores freer breathing through the nose
  • promotes nasal and/or sinus drainage
  • helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive.

Warnings

  • Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take:
  • more than 8 softgels in 24 hrs, which is the maximum daily amount for this product
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product
  • Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include:
  • skin reddening
  • blisters
  • rash If a skin reaction occurs, stop use and seek medical help right away.
  • Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.

Ask a doctor before use if

you have

  • liver disease
  • heart disease
  • high blood pressure
  • thyroid disease
  • diabetes
  • glaucoma
  • trouble urinating due to enlarged prostate gland
  • a sodium-restricted diet
  • cough that occurs with too much phlegm (mucus)
  • persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema

Ask a doctor or pharmacist before use if

you are taking the blood thinning drug warfarin; taking sedatives ot tranquilizers.

When using this product

do not use more than directed.

Stop use and ask a doctor if

  • you get nervous, dizzy or sleepless
  • pain, nasal congestion, or cough gets worse or lasts more than 7 days
  • fever gets worse or lasts more than 3 days
  • redness or swelling is present
  • new symptoms occur
  • cough comes back or occurs with rash or headache that lasts These could be signs of a serious condition.

If pregnant or breast-feeding

ask a health professional before use.

Keep out of reach of children

Overdose warning In case of overdose, get medical help or contact a Poison Control Center right away.

Directions

take only as directed do not exceed 8 softgels per 24 hrs

adults & children 12 yrs & over 2 softgels with water every 4 hrs
children 4 to under 12 yrs ask a doctor
children under 4 yrs do not use

Inactive ingredients

edible printing ink, FD&C blue no.1, FD&C red no.40, gelatin, glycerin, polyethylene glycol 400, povidone K30, propylene glycol, purified water, sorbitol sorbitan solution

Questions?

Call 1-888-423-0139

— FDA label of TopCare Day Time SEVERE Cold and Flu, Topco Associates LLC, effective December 4, 2023. See the official label on DailyMed →

CVS Maximum Strength Cold and Flu Relief · Cvs Pharmacy

Acetaminophen 650 mg/20 mL · Dextromethorphan hydrobromide 20 mg/20 mL · Guaifenesin 400 mg/20 mL · Phenylephrine hydrochloride 10 mg/20 mL, liquid (oral)

Active ingredient (in each 20 mL)

Purposes Acetaminophen 650 mg Pain reliever/fever reducer Dextromethorphan HBr 20 mg Cough suppressant Guaifenesin 400 mg Expectorant Phenylephrine HCl 10 mg Nasal decongestant

Purpose

Active ingredients (in each 20 mL) Purposes Acetaminophen 650 mg Pain reliever/fever reducer Dextromethorphan HBr 20 mg Cough suppressant Guaifenesin 400 mg Expectorant Phenylephrine HCl 10 mg Nasal decongestant

Uses

  • temporarily relieves these common cold and flu symptoms:
  • cough
  • nasal congestion
  • minor aches and pains
  • sore throat
  • sinus congestion and pressure
  • headache
  • temporarily reduces fever
  • temporarily promotes nasal and/or sinus drainage
  • helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive

Warnings

  • Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take:
  • more than 6 doses in 24 hours, which is the maximum daily amount
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks daily while using this product Generic Section Allergy alert : Acetaminophen may cause severe skin reactions. Symptoms may include:
  • skin
  • blisters
  • rash. If a skin reaction occurs, stop use and seek medical help right away.
  • Sore throat warning: if sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • for children under 12 years of age
  • if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.

Ask a doctor before use if

you have

  • liver disease
  • heart disease
  • high blood pressure
  • thyroid disease
  • diabetes
  • trouble urinating due to an enlarged prostate gland
  • persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema
  • cough that occurs with too much phlegm (mucus)

Ask a doctor or pharmacist before use if

  • you are taking the blood thinning drug warfarin

When using this product

do not use more than directed

Stop use and ask a doctor if

  • nervousness, dizziness, or sleeplessness occur
  • pain, nasal congestion, or cough gets worse, or lasts more than 7 days
  • fever gets worse, or lasts more than 3 days
  • redness or swelling is present
  • new symptoms occur
  • cough comes back, or occurs with rash, or persistent headache. These could be signs of a serious condition.

If pregnant or breast-feeding

ask a health professional before use.

Keep out of reach of children

Directions

  • do not take more than directed (see Overdose Warning) )
  • do not take more than 6 doses in any 24-hour period
  • measure only with dosing cup provided
  • do not use dosing cup with other products
  • dose as follows or as directed by a doctor
  • adults and children 12 years of age and older: 20 mL in dosing cup provided every 4 hours
  • children under 12 years of age: Do not use

Inactive ingredients

anhydrous citric acid, edetate disodium, FD&C blue #1, FD&C red #40, flavors, potassium citrate, propylene glycol, propyl gallate, purified water, sodium benzoate, sorbitol, sucralose, xanthan gum

Questions?

1-866-467-2748

— FDA label of CVS Maximum Strength Cold and Flu Relief, Cvs Pharmacy, effective August 19, 2026. See the official label on DailyMed →

Severe Tussin Cf · Cvs Woonsocket Prescription Center, Incorporated

Acetaminophen 650 mg/20 mL · Dextromethorphan hydrobromide 20 mg/20 mL · Guaifenesin 400 mg/20 mL · Phenylephrine hydrochloride 10 mg/20 mL, solution (oral)

Active ingredient (in each 20 mL)

Acetaminophen, USP 650 mg Dextromethorphan HBr, USP 20 mg Guaifenesin, USP 400 mg Phenylephrine HCl, USP 10 mg

Purpose

Pain reliever/fever reducer Cough suppressant Expectorant Nasal decongestant

Uses

  • temporarily relieves these symptoms occurring with a cold or flu:
  • cough due to minor throat and bronchial irritation
  • nasal congestion
  • sinus congestion and pressure
  • minor aches and pains
  • sore throat
  • headache
  • temporarily reduces fever
  • helps loosen phlegm (mucus) and thin bronchial secretions to drain bronchial tubes and make coughs more productive

Warnings

  • Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take
  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product
  • Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include:
  • skin reddening
  • blisters
  • rash If a skin reaction occurs, stop use and seek medical help right away.
  • Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.

Do not use

  • if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you have ever had an allergic reaction to this product or any of its ingredients

Ask a doctor before use if

you have

  • liver disease
  • heart disease
  • high blood pressure
  • thyroid disease
  • diabetes
  • trouble urinating due to an enlarged prostate gland
  • cough that occurs with too much phlegm (mucus)
  • persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema

Ask a doctor or pharmacist before use if

you are taking the blood thinning drug warfarin

When using this product

do not use more than directed

Stop use and ask a doctor if

  • you get nervous, dizzy or sleepless
  • pain, cough, or nasal congestion gets worse or lasts more than 7 days
  • fever gets worse or lasts more than 3 days
  • redness or swelling is present
  • new symptoms occur
  • cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition.

If pregnant or breast-feeding

ask a health professional before use.

Keep out of reach of children

  • Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Directions

do not take more than 5 doses in any 24-hour period

  • do not exceed recommended dosage. Taking more than the recommended dose (overdose) may cause serious liver damage.
  • measure only with dosing cup provided
  • keep dosing cup with product
  • mL = milliliter
  • this adult product is not intended for use in children under 12 years of age
age dose
adults and children 12 years and over 20 mL every 4 hours
children under 12 years do not use

Inactive ingredients

anhydrous citric acid, benzyl alcohol, edetate disodium, FD&C red #40, flavor, glycerin, polyethylene glycol, propylene glycol, purified water, sodium benzoate, sodium citrate, sorbitol solution, sucralose, xanthan gum

Questions?

1-800-719-9260

— FDA label of Severe Tussin Cf, Cvs Woonsocket Prescription Center, Incorporated, effective May 8, 2026. See the official label on DailyMed →

This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.

Same medicine, other brands

Each group lists the products that have exactly the same active ingredients, in the same amount and form, as registered with the FDA (NDC Directory). A store brand in the same group has the same medicine as the name brand; inactive ingredients, flavors and package sizes can differ. Each product links to its own official label.

Acetaminophen 325 mg · Dextromethorphan hydrobromide 10 mg · Guaifenesin 200 mg · Phenylephrine hydrochloride 5 mg · tablet, film coated (oral) · 52 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Basic Care Daytime Severe Cold and Flu Amazon.com Services LLC DailyMed
Cold and Flu Meijer Distribution, Inc. DailyMed
Cold and Flu Walmart Inc. DailyMed
Cold and Flu Daytime Severe L.N.K. International, Inc. DailyMed
Cold and Flu Daytime Severe Meijer Distribution Inc DailyMed
Cold and Flu Daytime Severe, 24/7 Life Lil' Drug Store Products, Inc. DailyMed
Cold and Flu maximum strength Rite Aid Corporation DailyMed
Cold and Flu Relief Severe WinCo Foods, LLC —
Cold and Flu Relief Severe Daytime Rite Aid Corporation DailyMed
Cold and Flu Severe Geiss, Destin & Dunn Inc. DailyMed
Cold and Flu Severe Meijer Distribution, Inc. DailyMed
Cold and Flu Severe Rite Aid Corporation DailyMed
Cold and Flu severe Wal-Mart Stores Inc DailyMed
Cold and Flu Severe Walgreen Company DailyMed
Cold Multi-Symptom Severe Valu Merchandisers Company DailyMed
Cold, Flu and Sore Throat Meijer Distribution, Inc. DailyMed
Cooling Severe Daytime CVS Pharmacy DailyMed
Daytime Cold and Flu Severe, Caseys 4good Lil' Drug Store Products, Inc. DailyMed
Daytime Cold and Flu Severe, Caseys 4goog Lil' Drug Store Products, Inc. DailyMed
Daytime Severe Cold and Flu Cvs Woonsocket Prescription Center, Incorporated DailyMed
Daytime Severe Cold Multi-Symptom United Natural Foods, Inc. dba UNFI DailyMed
DayTime Severe, Cold and Flu, 24-7 Life by 7-Eleven Lil' Drug Store Products, Inc. DailyMed
Dg Health Day Time Severe Cold and Flu Relief Dolgencorp, LLC DailyMed
Equate Vapor Ice Cold and Flu Wal-Mart Stores Inc DailyMed
Foster and Thrive Daytime Severe Cold and Flu Relief Sportpharm LLC DailyMed

Showing 25 of 52 brands.

Acetaminophen 325 mg · Dextromethorphan hydrobromide 10 mg · Guaifenesin 200 mg · Phenylephrine hydrochloride 5 mg · tablet, coated (oral) · 44 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, Phenylephrine Hydrochloride AAA Pharmaceutical, Inc. DailyMed
Cold and Flu Publix Super Markets Inc DailyMed
COLD and FLU SEVERE Discount Drug Mart DailyMed
Cold and Flu Severe Retail Business Services, LLC. ( DailyMed
Cold and Flu Severe Topcare DailyMed
Cold Flu and Sore Throat Publix Super Markets Inc DailyMed
Cold Flu and Sore Throat Retail Business Services, LLC. DailyMed
Cold Flu Severe AmeriSource Bergen DailyMed
Cold Flu Severe Harris Teeter —
Cold Flu Severe Heb DailyMed
Cold plus Flu Severe Chain Drug Marketing Association, Inc. DailyMed
Cold plus Flu Severe Hyvee Inc DailyMed
Cold plus Flu Severe Marc Glassman, Inc. DailyMed
Cold plus Flu Severe Valu Merchandisers Company DailyMed
Day Cold and Flu Target Corporation DailyMed
DayQuil Severe Plus VapoCOOL Cold And Flu Lil' Drug Store Products, Inc. DailyMed
DayQuil Severe plus VapoCOOL Cold and Flu, CVP HEALTH Lil' Drug Store Products, Inc. DailyMed
DayQuil Severe plus VapoCOOL Cold and Flu, Travel BASIX Lil' Drug Store Products, Inc. DailyMed
Daytime Severe Cold and Flu Discount Drug Mart DailyMed
Daytime Severe Cold and Flu Maximum Strength Heb DailyMed
Mucinex Fast-Max Cold, Flu and Sore Throat Reckitt Benckiser LLC DailyMed
Mucus Relief Cold and Flu Heb DailyMed
Mucus Relief Cold and Flu All in One Chain Drug Marketing Association Inc DailyMed
Mucus Relief Cold and Flu All in One Discount Drug Mart DailyMed
Mucus Relief Cold and Flu All in One Harris Teeter DailyMed

Showing 25 of 41 brands.

Acetaminophen 325 mg/15 mL · Dextromethorphan hydrobromide 10 mg/15 mL · Guaifenesin 200 mg/15 mL · Phenylephrine hydrochloride 5 mg/15 mL · solution (oral) · 36 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Basic Care Daytime Severe Cold and Flu Amazon.com Services LLC DailyMed
Careone daytime severe cold and flu American Sales Company DailyMed
Cold and Flu Relief Safeway DailyMed
Daytime Cold and Flu Meijer Distribution Inc DailyMed
Daytime Cold Flu Meijer, Inc. DailyMed
Daytime Severe Cvs Woonsocket Prescription Center, Incorporated DailyMed
Daytime Severe H E B DailyMed
Daytime Severe Cold and Flu Amazon.com Services LLC —
Daytime Severe Cold and Flu Cvs Woonsocket Prescription Center, Incorporated DailyMed
Daytime Severe Cold and Flu H E B DailyMed
Daytime Severe Cold and Flu Kroger Company DailyMed
Daytime Severe Cold and Flu Walgreen Company DailyMed
Daytime Severe Cold and Flu Relief Rite Aid Corporation DailyMed
DG Health Cold and Flu Relief Dolgencorp Inc —
DG Health Cold and Flu Severe Dolgencorp Inc DailyMed
Equaline Daytime Severe Cold and Flu Relief United Natural Foods, Inc. dba UNFI —
Equate Cold and Flu Walmart Inc. DailyMed
Equate Daytime Cold and Flu Wal-Mart Stores Inc DailyMed
Foster and Thrive Daytime Severe Cold and Flu Relief Strategic Sourcing Services LLC DailyMed
Good Sense Day Time Cold and Flu L. Perrigo Company DailyMed
Good Sense Severe Daytime Cold and Flu L. Perrigo Company DailyMed
Leader Daytime Severe Cold and Flu Cardinal Health 110, LLC. dba Leader DailyMed
Severe Cold and Flu Cvs Woonsocket Prescription Center, Incorporated DailyMed
Severe Cold and Flu HyVee Inc DailyMed
Severe Cold and Flu Walgreen Company DailyMed

Showing 25 of 32 brands.

Acetaminophen 325 mg · Dextromethorphan hydrobromide 10 mg · Guaifenesin 200 mg · Phenylephrine hydrochloride 5 mg · capsule, liquid filled (oral) · 34 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
ACETAMINOPHEN, DEXTROMETHORPHAN HBr, GUAILFENESIN,PHENLYEPHRINE HCL Kroger Company DailyMed
Acetaminophen, Guaifenesin, Dextromethorphan HBr, Phenylephrine HCl Opmx LLC —
Acetaminophen, Guaifenesin, Phenylephrine Hcl and Dextromethorphan HBr Softgel Healthcare Pvt Ltd DailyMed
Alka Seltzer COLD Cold Mucus Congestion Maximum Strength Fast Gels Bayer HealthCare LLC. DailyMed
Alka-Seltzer Plus Maximum Strength Cough, Mucus and Congestion Powermax Bayer HealthCare LLC. DailyMed
Cold and Flu Daytime Severe Target Corp DailyMed
COLD FLU and SORE THROAT RELIEF Foodhold U.S.A., LLC DailyMed
COLD, Flu and Sore Throat Walgreens DailyMed
DAYTIME COLD AND FLU Maximum Strength Walgreens DailyMed
Daytime Severe Cold and Flu Humanwell PuraCap Pharmaceutical (Wuhan), Ltd. DailyMed
Daytime Severe Cold and Flu Kroger Company DailyMed
Daytime Severe Cold and Flu Relief PuraCap Pharmaceutical LLC DailyMed
DayTime SEVERE Cold and Flu Relief SOFTGELS Topco Associates LLC DailyMed
equate MAXIMUM STRENGTH DAYTIME SEVERE Cold and Flu SOFTGELS Walmart Inc. DailyMed
HyVee Daytime Severe Cold and Flu SOFTGEL HyVee Inc DailyMed
Maximum Strength Cold and Flu CVS Pharmacy, Inc DailyMed
Maximum Strength Cold and Flu Family Dollar Services DailyMed
Maximum Strength Cold and Flu Target Corp DailyMed
Maximum Strength Cold and Flu Walgreens DailyMed
Maximum Strength Cold, Flu and Sore Throat CVS Pharmacy, Inc. DailyMed
Maximum Strength Mucinex Fast-Max Cold and Flu Reckitt Benckiser LLC DailyMed
Maximum Strength Non Drowsy Daytime Severe Cold and Flu Wal-Mart Stores Inc DailyMed
Mucinex Fast-Max Cold and Flu Maximum Strength Reckitt Benckiser LLC DailyMed
Mucinex Fast-Max Cold, Flu and Sore Throat Reckitt Benckiser LLC DailyMed
Mucinex Fast-Max Cold, Flu and Sore Throat Maximum Strength Reckitt Benckiser LLC DailyMed

Showing 25 of 34 brands.

Acetaminophen 650 mg/20 mL · Dextromethorphan hydrobromide 20 mg/20 mL · Guaifenesin 400 mg/20 mL · Phenylephrine hydrochloride 10 mg/20 mL · liquid (oral) · 26 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Cold Flu and Sore Throat Relief Maximum Strength Safeway, Inc. DailyMed
Cold, Flu and Sore Throat Maxium Strength DeMoulas Market Basket DailyMed
COLD, FLU and SORE THROAT RELIEF Better Living Brands, LLC DailyMed
CVS Maximum Strength Cold and Flu Relief Cvs Pharmacy DailyMed
CVS Maximum Strength Cold and Flu Relief Cvs Pharmacy, Inc DailyMed
CVS Severe Multi-Symptom Cough Cold Flu Cvs Pharmacy DailyMed
MAX Cold, Flu, and Sore Throat H E B DailyMed
Maximum Strength Mucus Relief Chain Drug Marketing Association Inc. DailyMed
Maximum Strength Mucus Relief Cold,Flu and Sore Throat Supervalu Inc DailyMed
Maximum Strength Mucus Relief Cold,Flu and Sore Throat Wal-Mart Stores, Inc. DailyMed
Meijer Adult Severe Multi-Symptom Cough Cold Flu Meijer Distribution Inc —
Mucosan Max with Acetaminophen Menper Distributors, Inc. DailyMed
Mucus Relief All in One Maximum Strength Dolgencorp, Inc. (DOLLAR GENERAL & REXALL) DailyMed
Mucus Relief All in One Maximum Strength Walgreens DailyMed
Mucus Relief Cold Flu and Sore Throat Maximum Strength Dolgencorp, Inc. (DOLLAR GENERAL & REXALL) DailyMed
Mucus Relief Cold Flu and Sore Throat Maximum Strength EQUATE (Wal-Mart Stores, Inc.) (see also WAL-MART INC) —
Mucus Relief Cold Flu and Sore Throat Maximum Strength Raritan Pharmaceuticals Inc DailyMed
Mucus Relief Cold Flu and Sore Throat Maximum Strength United Natural Foods, Inc. dba UNFI DailyMed
Mucus Relief Cold Flu Sore Throat Maximum Strength Walgreens DailyMed
Mucus Relief Maximum StrengthCold Flu and Sore Throat Walgreens DailyMed
Mucus Relief Severe Cold Daytime Maximum Strength TARGET Corporation DailyMed
Robitussin Severe Multi-Symptom Cough Cold Flu Haleon US Holdings LLC DailyMed
Rompe Pecho Max Multi Symptoms Efficient Laboratories Inc DailyMed
Tukol MAX ACTION Cold, Sore Throat and Cough Genomma Lab USA, Inc DailyMed
Tussnex FM Cold, Flu and Sore Throat Guardian Drug Company DailyMed

Showing 25 of 26 brands.

Acetaminophen 650 mg/20 mL · Dextromethorphan hydrobromide 20 mg/20 mL · Guaifenesin 400 mg/20 mL · Phenylephrine hydrochloride 10 mg/20 mL · solution (oral) · 18 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Basic Care Tussin Cf Severe Amazon.com Services LLC DailyMed
Cold and Flu Walgreen Company DailyMed
Cold, Flu and Sore Throat Family Dollar Services Inc —
Cold, Flu and Sore Throat Walgreen Company —
Complete Cold Relief Belmora LLC —
Dg Health Tussin Dolgencorp Inc DailyMed
Leader Tussin Cf Cardinal Health 110, LLC. dba Leader DailyMed
Maximum Strength Cold Flu and Sore Throat Kroger Company DailyMed
Maximum Strength Mucinex Fast-Max Cold and Flu Reckitt Benckiser LLC —
Mucinex Fast-Max Cold, Flu and Sore Throat Reckitt Benckiser LLC —
Mucinex Fast-Max Kickstart Severe Cold and Flu Reckitt Benckiser LLC —
Mucus Relief Cold, Flu and Sore Throat Topco Associates LLC DailyMed
Severe Tussin Cf Cvs Woonsocket Prescription Center, Incorporated DailyMed
Target Maximum Strength Cold Flu and Sore Throat Target Corporation DailyMed
Topcare Tussin Cf Max Topco Associates LLC DailyMed
Tussin Severe H E B DailyMed
WINCO Maximum StrengthCold Flu and Sore Throat Winco Foods, LLC DailyMed
Acetaminophen 325 mg · Dextromethorphan hydrobromide 10 mg · Guaifenesin 100 mg · Phenylephrine hydrochloride 5 mg · tablet, film coated (oral) · 14 products
Brand or product nameCompany on the labelLabel
CETAFEN COUGH and COLD HART Health DailyMed
Cold Terminator Cold Relief Wildman Business Group DailyMed
Head Congestion and Flu Severe Relief Rite Aid Corporation DailyMed
Medi-First Cough Cold Unifirst First Aid Corporation DailyMed
Medi-First Plus Cough Cold Unifirst First Aid Corporation DailyMed
Medique at Home Decorel Forte Sportpharm LLC DailyMed
Medique at Home Decorel Forte Unifirst First Aid Corporation DailyMed
Medique Decorel Forte Unifirst First Aid Corporation DailyMed
Multi-Symptom Cold Relief Unifirst First Aid Corporation DailyMed
Physicians Care Non-Drowsy Cold and Cough Acme United DailyMed
Sedalmex XL Flu Belmora LLC DailyMed
Sinus PE Head Congestion and Flu Severe Cvs Woonsocket Prescription Center, Incorporated DailyMed
SUDAFED PE Head Congestion Plus Flu Severe Kenvue Brands LLC DailyMed
Thompson Cough and Cold Multi-Symptom Relief Thompson DailyMed
Acetaminophen 325 mg · Dextromethorphan hydrobromide 10 mg · Guaifenesin 100 mg · Phenylephrine hydrochloride 5 mg · tablet, coated (oral) · 10 products
Brand or product nameCompany on the labelLabel
Head Congestion Flu Severe PE Chain Drug Marketing Association Inc DailyMed
Head Congestion Flu Severe PE Goodsense DailyMed
Head Congestion plus Flu Severe Heb DailyMed
Head Congestion plus Flu Severe United Natural Foods, Inc. dba UNFI DailyMed
Head Congestion plus Flu Severe PE Chain Drug Marketing Association, Inc. DailyMed
Head Congestion plus Flu Severe PE Discount Drug Mart DailyMed
Head Congestion plus Flu Severe PE Harris Teeter —
Head Congestion Plus Flu Severe Pe Retail Business Services, LLC. DailyMed
Head Congestion plus Flu Severe PE Topco Associates LLC DailyMed
Head Congestion plus Flu Severe PE Valu Merchandisers Company DailyMed
Acetaminophen 325 mg/15 mL · Dextromethorphan hydrobromide 10 mg/15 mL · Guaifenesin 200 mg/15 mL · Phenylephrine hydrochloride 5 mg/15 mL · liquid (oral) · 9 products
Brand or product nameCompany on the labelLabel
Daytime Severe Cold and Flu Grocery Outlet, Inc. DailyMed
Daytime Severe Cold and Flu Kroger DailyMed
Daytime Severe Cold and Flu Relief Family Dollar (FAMILY WELLNESS) DailyMed
Severe Cold and Flu Daytime Honey Kroger DailyMed
Severe Cold and Flu Relief Daytime Dolgencorp, Inc. (DOLLAR GENERAL & REXALL) —
Severe Cold and Flu Relief Daytime P & L Development, LLC DailyMed
Severe Cold and Flu Relief Daytime Walgreens DailyMed
Vicks DayQuil Severe Honey Cold and Flu Procter & Gamble Manufacturing Company —
VICKS DayQuil SEVERE HONEY FLAVOR COLD and FLU Procter & Gamble Manufacturing Company —
Acetaminophen 325 mg/10 mL · Dextromethorphan hydrobromide 10 mg/10 mL · Guaifenesin 200 mg/10 mL · Phenylephrine hydrochloride 5 mg/10 mL · liquid (oral) · 7 products
Brand or product nameCompany on the labelLabel
CHILDRENS COLD COUGH and SORE THROAT MIXED BERRY AptaPharma Inc. DailyMed
Childrens Multi-symptom Cold and Fever Liquid Wal-Mart Stores, Inc. DailyMed
Childrens Tukol Multi-Symptom Cold and Flu Genomma Lab USA, Inc. DailyMed
Childrens Tussnex Guardian Drug Company DailyMed
Cough Cold and Sore Throat Childrens Walgreens DailyMed
Mucus Relief Cough Cold Sore Throat H E B DailyMed
SanaTos X Children Pharmadel LLC DailyMed
Acetaminophen 325 mg · Dextromethorphan hydrobromide 10 mg · Guaifenesin 200 mg · Phenylephrine hydrochloride 5 mg · tablet (oral) · 4 products
Brand or product nameCompany on the labelLabel
DayQuil Severe plus Vicks VapoCool Cold and Flu The Procter & Gamble Manufacturing Company DailyMed
DoloMax Cold Cough Benard Industries Inc DailyMed
Head and Cold Hi-Tech Nutraceuticals, LLC DailyMed
Vicks DayQuil VapoCOOL SEVERE COLD and FLU plus CONGESTION The Procter & Gamble Manufacturing Company DailyMed
Acetaminophen 325 mg/10 mL · Dextromethorphan hydrobromide 10 mg/10 mL · Guaifenesin 200 mg/10 mL · Phenylephrine hydrochloride 5 mg/10 mL · solution (oral) · 4 products
Brand or product nameCompany on the labelLabel
Mucinex Childrens Cold and Flu Reckitt Benckiser LLC DailyMed
Mucinex Childrens FreeFrom Multi-Symptom Cold, Flu and Sore Throat Reckitt Benckiser LLC DailyMed
Mucinex Childrens Multi-Symptom Cold and Sore Throat Reckitt Benckiser LLC DailyMed
Multi-Symptom Cold and Fever Childrens Cvs Pharmacy DailyMed
Acetaminophen 250 mg/10 mL · Dextromethorphan hydrobromide 13.33 mg/10 mL · Guaifenesin 200 mg/10 mL · Phenylephrine hydrochloride 5 mg/10 mL · syrup (oral) · 4 products
Brand or product nameCompany on the labelLabel
Pentrexcilina Children TOTAL RELIEF Multi-Symptom Opmx LLC —
Rompe Tos X Children Opmx LLC DailyMed
Tenalif Children Opmx LLC DailyMed
Tesalon Children Opmx LLC DailyMed
Acetaminophen 650 mg/30 mL · Dextromethorphan hydrobromide 20 mg/30 mL · Guaifenesin 400 mg/30 mL · Phenylephrine hydrochloride 10 mg/30 mL · liquid (oral) · 4 products
Brand or product nameCompany on the labelLabel
CVS Daytime Cold and Flu Relief Cvs Pharmacy DailyMed
Daytime Cold and Flu Relief The Kroger Co. DailyMed
Daytime Cold and Flu Relief Walgreens Co. DailyMed
Severe Cold and Flu Daytime Kroger Company DailyMed
Acetaminophen 500 mg/20 mL · Dextromethorphan hydrobromide 26.66 mg/20 mL · Guaifenesin 400 mg/20 mL · Phenylephrine hydrochloride 10 mg/20 mL · syrup (oral) · 4 products
Brand or product nameCompany on the labelLabel
Pentrexcilina Adult TOTAL RELIEF Multi-Symptom Opmx LLC —
Rompe Tos X Adults Opmx LLC DailyMed
Tenalif Multi Symptom Relief Opmx LLC DailyMed
Tesalon Jarabe Adulto Opmx LLC —
Acetaminophen 650 mg/30 mL · Dextromethorphan hydrobromide 20 mg/30 mL · Guaifenesin 400 mg/30 mL · Phenylephrine hydrochloride 10 mg/30 mL · solution (oral) · 3 products
Brand or product nameCompany on the labelLabel
Cold and Flu plus Congestion Daytime Walmart Inc. DailyMed
DayQuil VapoCOOL SEVERE COLD and FLU plus CONGESTION The Procter & Gamble Manufacturing Company —
Tylenol Cold Plus Flu Severe Kenvue Brands LLC DailyMed
Acetaminophen 250 mg · Dextromethorphan hydrobromide 10 mg · Guaifenesin 200 mg · Phenylephrine hydrochloride 5 mg · capsule, liquid filled (oral) · 2 products
Brand or product nameCompany on the labelLabel
Alka-Seltzer Plus Severe Cough Mucus and Congestion Liquid Gels Bayer HealthCare LLC. DailyMed
Alka-Seltzer Plus Severe Sinus Cold and Cough Liquid Gels Bayer HealthCare LLC. DailyMed
Acetaminophen 500 mg · Dextromethorphan hydrobromide 20 mg · Guaifenesin 400 mg · Phenylephrine hydrochloride 10 mg · powder, for solution (oral) · 2 products
Brand or product nameCompany on the labelLabel
ALKA SELTZER COLD Cold Flu And Congestion Severe Fast Hot Liquid Day Bayer HealthCare LLC. DailyMed
Alka-Seltzer Plus Day Severe Cold Plus Flu Bayer HealthCare LLC. DailyMed
Acetaminophen 325 mg · Dextromethorphan hydrobromide 15 mg · Guaifenesin 200 mg · Phenylephrine hydrochloride 5 mg · tablet (oral) · 2 products
Brand or product nameCompany on the labelLabel
COLDTAC Plus Opmx LLC DailyMed
SanaTos Multi Symptom Pharmadel LLC DailyMed
Acetaminophen 325 mg · Dextromethorphan hydrobromide 10 mg · Guaifenesin 200 mg · Phenylephrine hydrochloride 5 mg · capsule (oral) · 2 products
Brand or product nameCompany on the labelLabel
Daytime Severe Cold and Flu Cvs Health Corp DailyMed
Severe Cold Daytime CVS Pharmacy DailyMed

8 more strengths and forms are listed in the FDA NDC Directory.

What pharmacies pay (NADAC)

The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.

This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.

NADAC per unit for Acetaminophen, dextromethorphan, guaifenesin and phenylephrine, by strength and form
Strength and formGeneric or brandPharmacies pay
acetaminophen 325 mg · dextromethorphan hydrobromide 10 mg · guaifenesin 200 mg · phenylephrine hydrochloride 5 mg
tablet, coated
Generic $0.1323 per tablet
acetaminophen 325 mg · dextromethorphan hydrobromide 10 mg · guaifenesin 200 mg · phenylephrine hydrochloride 5 mg
tablet, film coated
Generic $0.1323 per tablet
acetaminophen 650 mg/20 mL · dextromethorphan hydrobromide 20 mg/20 mL · guaifenesin 400 mg/20 mL · phenylephrine hydrochloride 10 mg/20 mL
solution
Generic $0.0241 per mL

NADAC list of November 4, 2026; these prices took effect between May 20, 2026 and October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.

Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →

Companies that sell this medicine

The company named on the package (maker or distributor), as listed in the FDA NDC Directory, with its number of over-the-counter products of this medicine.

  • Reckitt Benckiser LLC18 products
  • Chain Drug Marketing Association Inc12 products
  • Lil Drug Store Products, Inc11 products
  • Walgreens10 products
  • Opmx LLC10 products
  • Topco Associates LLC9 products
  • CVS Pharmacy8 products
  • Cvs Woonsocket Prescription Center, Incorporated8 products
  • Meijer Distribution Inc7 products
  • Discount Drug Mart6 products
  • Bayer HealthCare LLC.6 products
  • Amazon.com Services LLC6 products
  • Rite Aid Corporation6 products
  • Valu Merchandisers Company6 products
  • Walgreen Company6 products
  • Wal-Mart Stores Inc6 products
  • Harris Teeter5 products
  • Target Corporation5 products
  • The Procter & Gamble Manufacturing Company5 products
  • Unifirst First Aid Corporation5 products
  • H E B5 products
  • United Natural Foods, Inc. dba UNFI5 products
  • HyVee Inc5 products
  • Heb5 products
  • Kroger Company5 products
  • Walmart Inc.4 products
  • Kenvue Brands LLC4 products
  • Pharmadel LLC4 products
  • Cardinal Health 110, LLC. dba Leader4 products
  • Publix Super Markets Inc3 products

Showing the 30 companies with the most products, of 94.

Recalls

From FDA enforcement reports, matched by the product’s NDC code or label. A recall usually covers specific products or lots: check the name and lot number on your package.

  1. October 11, 2022 · Class III · Terminated · D-0014-2023

    Boxes mislabeled to read "Decongestant Free", but the product contains Phenylephrine HCI 5mg

    NDC 0363-6171-09 Walgreens Sinus Pressure, Pain & Cough ACETAMINOPHEN/ PAIN RELIEVER DEXTROMETHORPHAN HBr/ COUGH SUPPRESSANT GUAIFENESIN/ EXPECTORANT PHENYLEPHRINE HCl/ NASAL DECONGESTANT Maximum Strength Decongestant Fr — LNK International, Inc.

  2. August 24, 2021 · Class II · Terminated · D-0293-2022

    Microbial Contamination of Non-Sterile Products

    Rompe Pecho Max Multi-Symptoms Maximum Strength, 8 Fl. Oz. (237 mL) bottles, Distributed by: Efficient Laboratories, Inc. Miami, FL 33166 UPC 0 00856 00309 5, NDC 58593-828-08 — Efficient Laboratories, Inc.

  3. April 15, 2015 · Class I · Terminated · D-1363-2015

    Labeling: Label Mix-Up; Bottles of Mucinex Fast-Max liquid are correctly labeled on the front of the label, however the back of the bottle where the Drug Facts labeling is, is missing certain Active Ingredients such as acetaminophen, phenylephrine, dextromethorphan, diphenhydramine, and/or guaifenesin. As a result cert

    Mucinex Fast Max Cold, Flu & Sore Throat, Maximum Strength, Acetaminophen Pain Reliever/Fever Reducer, Dextromethorphan HBr Cough Suppressant, Guaifenesin Expectorant, Phenylephrine HCl Nasal Decongestant, 6 fl oz (180 m — Reckitt Benckiser LLC

Sources

  1. Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  2. NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  3. Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
  4. FDA rule for the Drug Facts label (21 CFR 201.66)

Only medicines marketed under FDA rules for nonprescription drugs (an FDA monograph or an FDA approval) are listed. Homeopathic products are not listed: the FDA does not evaluate them for safety or effectiveness.

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