Quick answers
- What is Acetaminophen, dextromethorphan and doxylamine used for?
- The Drug Facts label of Dr. Simi Nighttime Cold and Flu (Farmacias De Similares TX LLC) lists these uses: temporarily relieves common cold/flu symptoms; cough due to minor throat & bronchial irritation; sore throat; headache; minor aches & pains; fever; runny nose & sneezing.
- Do I need a prescription for Acetaminophen, dextromethorphan and doxylamine?
- No. The products on this page are sold without a prescription (over the counter).
- Is a store brand the same as the name brand?
- Products listed together below have the same active ingredients, in the same amount and the same form, as registered with the FDA. Inactive ingredients (such as colors, flavors and fillers) and package sizes can differ. Compare the “Active ingredient” box on both packages, and ask a pharmacist if you are not sure.
- Has Acetaminophen, dextromethorphan and doxylamine been recalled?
- No recall linked to these products appears in the FDA enforcement reports we use.
Drug Facts label
Every over-the-counter medicine must carry a “Drug Facts” box in the same order, set by FDA rules. Below is the label of one product for each common strength and form, quoted word for word. Your own package can differ (for example, children’s products have other directions): always follow the label on your package.
Dr. Simi Nighttime Cold and Flu · Farmacias De Similares TX LLC
Acetaminophen 325 mg · Dextromethorphan hydrobromide 15 mg · Doxylamine succinate 6.25 mg, capsule, liquid filled (oral)
Active ingredient
Drug Facts Active ingredients (in each softgel) Acetaminophen 325 mg Dextromethorphan HBr 15 mg Doxylamine succinate 6.25 mg
Purpose
Acetaminophen 325 mg Pain reliever/ fever reducer Dextromethorphan HBr 15 mg Cough suppressant Doxylamine succinate 6.25 mg Antihistamine
Uses
temporarily relieves common cold/flu symptoms:
- cough due to minor throat & bronchial irritation
- sore throat
- headache
- minor aches & pains
- fever
- runny nose & sneezing
Warnings
- Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take:
- more than 8 softgels in 24 hrs, which is the maximum daily amount for this product
- with other drugs containing acetaminophen
- 3 or more alcoholic drinks daily while using this product Allergy Alert: Acetaminophen may cause severe skin reactions. Symptoms may include:
- skin reddening
- blisters
- rash If a skin reaction occurs, stop use and seek medical help right away.
- Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.
Do not use
- with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
- if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
Ask a doctor before use if
you have
- liver disease
- glaucoma
- cough that occurs with too much phlegm (mucus)
- a breathing problem or chronic cough that lasts or as occurs with smoking, asthma, chronic bronchitis or emphysema
- trouble urinating due to enlarged prostate gland
Ask a doctor or pharmacist before use if
you are
- taking sedatives or tranquilizers
- taking the blood thinning drug warfarin
When using this product
- do not exceed recommended dosage
- excitability may occur, especially in children
- marked drowsiness may occur
- avoid alcoholic drinks
- be careful when driving a motor vehicle or operating machinery
- alcohol, sedatives & tranquilizers may increase drowsiness
Stop use and ask a doctor if
- pain or cough gets worse or lasts more than 7 days
- fever gets worse or lasts more than 3 days
- redness or swelling is present
- new symptoms occur
- cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition.
If pregnant or breast-feeding
ask a health professional before use.
Keep out of reach of children
In case of accidental overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as children, even if you do not notice any signs or symptoms.
Directions
take only as directed (see Warnings)
- do not exceed 4 doses per 24 hrs
| adults & children 12 years and over | 2 softgels with water every 6 hours |
| children 4 to under 12 years | ask a doctor |
| children under 4 years | do not use |
- When using other daytime or nighttime products, carefully read each label to ensure correct dosing
Other information
- Store at room temperature 20-25°C (68-77°F)
- avoid excessive heat
Inactive ingredients
D&C Yellow No. 10, FD&C Blue No. 1, gelatin, glycerin, polyethylene glycol, povidone, propylene glycol, purified water, sorbitol sorbitan solution, titanium dioxide
Questions?
855-280-1079
— FDA label of Dr. Simi Nighttime Cold and Flu, Farmacias De Similares TX LLC, effective March 30, 2026. See the official label on DailyMed →
Nighttime Cherry Cold and Flu · Better Living Brands LLC.
Acetaminophen 650 mg/30 mL · Dextromethorphan hydrobromide 30 mg/30 mL · Doxylamine succinate 12.5 mg/30 mL, liquid (oral)
Active ingredient (in each 30 mL)
Acetaminophen 650 mg Dextromethorphan HBr 30 mg Doxylamine succinate 12.5 mg
Purpose
Pain reliever/fever reducer Cough suppressant Antihistamine
Uses
temporarily relieves common cold/flu symptoms:
- cough due to minor throat and bronchial irritation
- sore throat
- headache
- minor aches and pains
- fever
- runny nose and sneezing
Warnings
- Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take
- more than 4 doses in 24 hours, which is the maximum daily amount for this product
- with other drugs containing acetaminophen
- 3 or more alcoholic drinks every day while using this product
- Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include:
- skin reddening
- blisters
- rash If a skin reaction occurs, stop use and seek medical help right away.
- Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.
Do not use
- with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
- if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
Ask a doctor before use if
you have
- liver disease
- glaucoma
- cough that occurs with too much phlegm (mucus)
- a breathing problem or chronic cough that lasts or as occurs with smoking, asthma, chronic bronchitis, or emphysema
- trouble urinating due to enlarged prostate gland
Ask a doctor or pharmacist before use if
you are
- taking sedatives or tranquilizers
- taking the blood thinning drug warfarin
When using this product
- excitability may occur, especially in children
- marked drowsiness may occur
- avoid alcoholic drinks
- be careful when driving a motor vehicle or operating machinery
- alcohol, sedatives, and tranquilizers may increase drowsiness
Stop use and ask a doctor if
- pain or cough gets worse or lasts more than 7 days
- fever gets worse or lasts more than 3 days
- redness or swelling is present
- new symptoms occur
- cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition.
If pregnant or breast-feeding
ask a health professional before use.
Keep out of reach of children
In case of overdose, get medical help or contact a Poison Control Center (1-800-222-1222) right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Directions
take only as directed
- only use the dose cup provided
- do not exceed 4 doses per 24 hrs
| adults & children 12 yrs & over | 30 mL every 6 hrs |
| children 4 to under 12 yrs | ask a doctor |
| children under 4 yrs | do not use |
Other information
- each 30 mL contains: sodium 52 mg
- store at no greater than 25°C and do not refrigerate
Inactive ingredients
alcohol, anhydrous citric acid, FD&C blue no. 1, FD&C red no. 40, flavor, glycerin, polyethylene glycol, propylene glycol, purified water, sodium benzoate, sodium citrate, sodium saccharin, sorbitol solution, sucralose, xanthan gum
Questions?
Call 1-877-290-4008
— FDA label of Nighttime Cherry Cold and Flu, Better Living Brands LLC., effective March 3, 2026. See the official label on DailyMed →
Kroger Nighttime Cold and Flu Relief · Kroger Company
Acetaminophen 650 mg/30 mL · Dextromethorphan hydrobromide 30 mg/30 mL · Doxylamine succinate 12.5 mg/30 mL, solution (oral)
Active ingredient (in each 30 mL)
Acetaminophen 650 mg Dextromethorphan HBr 30 mg Doxylamine succinate 12.5 mg
Purpose
Pain reliever/fever reducer Cough suppressant Antihistamine
Uses
temporarily relieves common cold/flu symptoms:
- cough due to minor throat and bronchial irritation
- sore throat
- headache
- minor aches and pains
- fever
- runny nose and sneezing
Warnings
- Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take
- more than 4 doses in 24 hours, which is the maximum daily amount for this product
- with other drugs containing acetaminophen
- 3 or more alcoholic drinks every day while using this product
- Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include:
- Skin reddening
- Blisters
- Rash If a skin reaction occurs, stop use and seek medical help right away.
- Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.
Do not use
- with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
- if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
- if you have ever had an allergic reaction to this product or any of its ingredients
Ask a doctor before use if
you have
- liver disease
- glaucoma
- cough that occurs with too much phlegm (mucus)
- a breathing problem such as emphysema or chronic bronchitis
- trouble urinating due to an enlarged prostate gland
- persistent or chronic cough as occurs with smoking, asthma, or emphysema
- a sodium-restricted diet
Ask a doctor or pharmacist before use if
you are
- taking sedatives or tranquilizers
- taking the blood thinning drug warfarin
When using this product
- excitability may occur, especially in children
- marked drowsiness may occur
- avoid alcoholic drinks
- be careful when driving a motor vehicle or operating machinery
- alcohol, sedatives, and tranquilizers may increase drowsiness
Stop use and ask a doctor if
- pain or cough gets worse or lasts more than 7 days
- fever gets worse or lasts more than 3 days
- redness or swelling is present
- new symptoms occur
- cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition.
If pregnant or breast-feeding
ask a health professional before use.
Keep out of reach of children
- Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Directions
take only as directed
- only use the dose cup provided
- do not exceed 4 doses per 24 hrs
| adults & children 12 yrs & over | 30 mL every 6 hrs |
| children 4 to under 12 yrs | ask a doctor |
| children under 4 yrs | do not use |
Inactive ingredients
alcohol, anhydrous citric acid, FD&C blue no. 1, FD&C red no. 40, flavor, propylene glycol, propyl gallate, purified water, sodium benzoate, sodium citrate, sorbitol liquid, sucralose. Questions or comments? 1-866-467-2748
Questions?
1-866-467-2748
— FDA label of Kroger Nighttime Cold and Flu Relief, Kroger Company, effective September 2, 2026. See the official label on DailyMed →
Acetaminophen, Dextromethorphan Hydrobromide and Doxylamine Succinate · Softgel Healthcare Private Limited
Acetaminophen 325 mg · Dextromethorphan hydrobromide 10 mg · Doxylamine succinate 6.25 mg, capsule, liquid filled (oral)
Active ingredient (in each capsule)
Acetaminophen USP 325 mg Dextromethorphan HBr USP 10 mg Doxylamine Succinate USP 6.25 mg
Purpose
Pain reliever/fever reducer Cough suppressant Antihistamine
Uses
- temporarily relieves these symptoms due to a cold or flu :
- minor aches and pains
- headache
- cough
- sore throat
- nasal and sinus congestion
- temporarily reduces fever
Warnings
- Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take
- more than 4,000 mg of acetaminophen in 24 hours
- with other drugs containing acetaminophen
- 3 or more alcoholic drinks every day while using this product
- Allergy alert: Acetaminophen may cause severe skin or severe allergic reactions. Symptoms may include:
- skin reddening
- blisters
- rash
- hives
- facial swelling
- asthma (wheezing)
- shock If a skin or general allergic reaction occurs, stop use and seek medical help right away
- Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.
Do not use
- with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
- if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
- if you have ever had an allergic reaction to this product or any of its ingredients
- in children under 12 years of age
Ask a doctor before use if
you have
- liver disease
- heart disease
- high blood pressure
- thyroid disease
- diabetes
- cough that occurs with excessive phlegm (mucus)
- difficulty in urination due to enlargement of the prostate gland
- persistent or chronic cough such as occurs with smoking, asthma, or emphysema
Ask a doctor or pharmacist before use if
you are taking the blood thinning drug warfarin
When using this product
do not exceed recommended dosage
Stop use and ask a doctor if
- pain, cough, or nasal congestion gets worse or lasts more than 7 days
- fever gets worse or lasts more than 3 days
- redness or swelling is present
- new symptoms occur
- cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition.
- nervousness, dizziness, or sleeplessness occurs
If pregnant or breast-feeding
ask a health professional before use.
Keep out of reach of children
In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Directions
- do not take more than the recommended dose
- adults and children 12 years and over: take 2 capsules with water every 4 hours. Do not exceed 10 capsules in 24 hours or as directed by a doctor.
- children under 12 years: do not use
Other information
- store at room temperature. Avoid excessive heat above 40ºC (104ºF).
Inactive ingredients
D&C yellow no.10, FD&C blue no.1, gelatin, glycerin, mica, polyethylene glycol 400, povidone K 30, purified water, sorbitol sorbitan solution, titanium dioxide
— FDA label of Acetaminophen, Dextromethorphan Hydrobromide and Doxylamine Succinate, Softgel Healthcare Private Limited, effective January 27, 2026. See the official label on DailyMed →
NyQuil Cold and Flu w/VapoCOOL, 4ct, Travel BASIX · Lil' Drug Store Products, Inc.
Acetaminophen 325 mg · Dextromethorphan hydrobromide 10 mg · Doxylamine succinate 6.25 mg, tablet, coated (oral)
Active ingredient
Active ingredients Active ingredients (in each caplet) Acetaminophen 325 mg Dextromethorphan HBr 10 mg Doxylamine succinate 6.25 mg Purpose Purpose Pain reliever/fever red Cough suppressant Antihistamine
Purpose
Purpose Pain reliever/fever red Cough suppressant Antihistamine
Uses
Uses temporarily relieves common cold/flu symptoms: cough due to minor throat & bronchial irritation cough to help you sleep sore throat headache minor aches & pains fever runny nose & sneezing
Warnings
Liver warning
- Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take more than 8 caplets in 24 hours, which is the maximum daily amount for this product with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy Alert Allergy Alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening blisters rash If a skin reaction occurs, stop use and seek medical help right away
- Sore throat warning Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.
Do not use
Do not use
- with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
- if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Ask a doctor before use
Ask a doctor before use if
you have liver disease glaucoma cough that occurs with too much phlegm (mucus) a breathing problem or chronic cough that lasts or as occurs with smoking, asthma, chronic bronchitis, or emphysema trouble urinating due to enlarged prostate gland Ask a doctor or pharmacist before use
Ask a doctor or pharmacist before use if
you are taking sedatives or tranquilizers taking the blood thinning drug warfarin
When using this product
When using this product
excitability may occur, especially in children marked drowsiness may occur alcohol, sedatives, and tranquilizers may increase drowsiness avoid alcoholic drinks be careful when driving a motor vehicle or operating machinery Stop use and ask a doctor
Stop use and ask a doctor if
pain or cough gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition.
If pregnant or breast-feeding
If pregnant or breast-feeding
ask a health professional before use.
Keep out of reach of children
Keep out of reach of children
In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Directions
Directions take only as directed do not exceed 8 caplets per 24 hrs
| adults & children 12 yrs & over | 2 caplets with water every 4 hrs |
| children 4 to under 12 yrs | ask a doctor |
| children under 4 yrs | do not use |
Inactive ingredients
Inactive ingredients corn starch, D&C Yellow #10 Aluminum Lake, FD&C Blue #2 Aluminum Lake, FD&C Yellow #6 Aluminum Lake, flavor, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone, silicon dioxide, stearic acid, sucralose, talc, titanium dioxide
Questions?
Questions? 1-800-362-1683
— FDA label of NyQuil Cold and Flu w/VapoCOOL, 4ct, Travel BASIX, Lil' Drug Store Products, Inc., effective June 17, 2025. See the official label on DailyMed →
Nighttime Cold and Flu Relief · Aurohealth LLC
Acetaminophen 325 mg · Dextromethorphan hydrobromide 15 mg · Doxylamine succinate 6.25 mg, capsule (oral)
Active ingredient (in each capsule)
Acetaminophen USP 325 mg Dextromethorphan HBr USP 15 mg Doxylamine succinate USP 6.25 mg
Purpose
Pain reliever/fever reducer Cough suppressant Antihistamine
Uses
temporarily relieves common cold/flu symptoms: cough due to minor throat & bronchial irritation sore throat headache minor aches & pains fever runny nose & sneezing
Warnings
- Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take more than 8 capsules in 24 hours, which is the maximum daily amount for this product with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy Alert: Acetaminophen may cause severe skin reactions. Symptoms may include:
- skin reddening
- blisters
- rash If a skin reaction occurs, stop use and seek medical help right away
- Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.
Do not use
with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
Ask a doctor before use if
you have liver disease glaucoma cough that occurs with too much phlegm (mucus) a breathing problem or chronic cough that lasts or as occurs with smoking, asthma, chronic bronchitis, or emphysema trouble urinating due to enlarged prostate gland
Ask a doctor or pharmacist before use if
you are taking sedatives or tranquilizers taking the blood thinning drug warfarin
When using this product
do not use more than directed excitability may occur, especially in children marked drowsiness may occur avoid alcoholic drinks be careful when driving a motor vehicle or operating machinery alcohol, sedatives, and tranquilizers may increase drowsiness
Stop use and ask a doctor if
pain or cough gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition.
If pregnant or breast-feeding
ask a health professional before use.
Keep out of reach of children
In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Directions
take only as directed do not exceed 8 capsules per 24 hrs
| adults & children 12 yrs & over | 2 capsules with water every 6 hrs |
| children 4 to under 12 yrs | ask a doctor |
| children under 4 yrs | do not use |
Inactive ingredients
D&C Yellow No. 10, gelatin, glycerin, Neelicert FD&C Blue No. 1, polyethylene glycol, povidone, propylene glycol, purified water, shellac glaze, sorbitol sorbitan solution, titanium dioxide Questions or comments? call 1-855-274-4122
Questions?
Distributed by: AUROHEALTH LLC 279 Princeton-Hightstown Road East Windsor, NJ 08520 Made in India
— FDA label of Nighttime Cold and Flu Relief, Aurohealth LLC, effective April 28, 2025. See the official label on DailyMed →
This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.
Same medicine, other brands
Each group lists the products that have exactly the same active ingredients, in the same amount and form, as registered with the FDA (NDC Directory). A store brand in the same group has the same medicine as the name brand; inactive ingredients, flavors and package sizes can differ. Each product links to its own official label.
Acetaminophen 325 mg · Dextromethorphan hydrobromide 15 mg · Doxylamine succinate 6.25 mg · capsule, liquid filled (oral) · 78 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Acetaminophen, Dextromethorphan Hydrobromide and Doxylamine Succinate | Softgel Healthcare Private Limited | DailyMed |
| Ampigrin Ultra Forte Night | Opmx LLC | DailyMed |
| AXIV NightTime | Vivunt Pharma LLC | DailyMed |
| Basic Care Nighttime Cold and Flu | Amazon.com Services LLC | DailyMed |
| Circle K Nighttime Cold and Flu | Lil' Drug Store Products, Inc. | DailyMed |
| Cold and Flu | HyVee Inc | DailyMed |
| Cold and Flu Relief | Dolgencorp, Inc. (DOLLAR GENERAL & REXALL) | DailyMed |
| Cold and Flu Relief Nighttime | Dolgencorp, Inc. (DOLLAR GENERAL & REXALL) | DailyMed |
| Cold and Flu Relief Nighttime | Safeway, Inc. | DailyMed |
| DG Health Cold and Flu Relief | Dolgencorp Inc | DailyMed |
| Dr. Simi Nighttime Cold and Flu | Farmacias De Similares TX LLC | DailyMed |
| DRX CHOICE NIGHTTIME COLD and FLU RELIEF | Raritan Pharmaceuticals Inc. | DailyMed |
| Good Neighbor Pharmacy Night Time | Amerisource Bergen | DailyMed |
| Good Sense Night Time | L. Perrigo Company | DailyMed |
| GoodMeds Nighttime Cold and Flu | Cabinet Health P.B.C. | — |
| Kroger NightTime Cold and Flu SOFTGEL | The Kroger Co. | DailyMed |
| Kroger Nighttime Cold and Flu Softgel | The Kroger Company | DailyMed |
| meijer Nighttime Cold and Flu SOFTGEL | Meijer, Inc. | DailyMed |
| Multi-Symptom Cold and Flu Relief Nighttime | Rite Aid | DailyMed |
| Multi-Symptom Nighttime Cold and Flu Relief | Advanced Rx LLC | DailyMed |
| Night Time | H E B | DailyMed |
| Night Time Cold and Flu Multi Symptom | QUALITY CHOICE (Chain Drug Marketing Association) | DailyMed |
| Night Time Cold and Flu Relief | FSA Store Inc. (Caring Mills) | DailyMed |
| Night Time Cold and Flu Relief | Major Pharmaceuticals | DailyMed |
| Night Time Cold and Flu relief liquid filled softgels | AptaPharma Inc. | DailyMed |
Showing 25 of 70 brands.
Acetaminophen 650 mg/30 mL · Dextromethorphan hydrobromide 30 mg/30 mL · Doxylamine succinate 12.5 mg/30 mL · liquid (oral) · 62 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| AXIM Night Time - Liquid | Vivunt Pharma LLC | DailyMed |
| AXIV Night Time - Liquid | Vivunt Pharma LLC | DailyMed |
| Circle K Nighttime Cold and Flu | Lil' Drug Store Products, Inc | DailyMed |
| Cold and Flu Nighttime | Best Choice (Valu Merchandisers Company) | DailyMed |
| Cold and Flu Nighttime | Dolgencorp, Inc. (DOLLAR GENERAL & REXALL) | DailyMed |
| Cold and Flu Nighttime | QUALITY CHOICE (Chain Drug Marketing Association) | DailyMed |
| Cold and Flu Nighttime | Walgreens | DailyMed |
| Cold and Flu Relief Multi Symptom Nighttime | WinCo Foods, LLC | DailyMed |
| Cold and Flu Relief Nighttime | Rite Aid Corporation | DailyMed |
| Family Dollar Nighttime Cold and Flu Relief | Family Dollar Services Inc | — |
| Night Time Cold and Flu original | Harris Teeter, LLC | DailyMed |
| Night Time Cold and Flu ReadyInCase | P & L Development, LLC | DailyMed |
| NIGHT-TIME MULTI-SYMPTOM COLD/FLU Cherry | DeMoulas Market Basket | DailyMed |
| NIGHT-TIME MULTI-SYMPTOM COLD/FLU Original | DeMoulas Market Basket | DailyMed |
| Night-Time Multi-Symptom Cold/Flu Relief | Discount Drug Mart | — |
| Nighttime Cherry Cold and Flu | Better Living Brands LLC. | DailyMed |
| Nighttime Cherry Cold and Flu | Target Corporation | DailyMed |
| Nighttime Cold and Flu | Better Living Brands LLC. | DailyMed |
| Nighttime Cold and Flu | Bi-Mart | DailyMed |
| Nighttime Cold and Flu | Cvs Pharmacy, Inc | DailyMed |
| Nighttime Cold and Flu | Grocery Outlet, Inc. | DailyMed |
| Nighttime Cold and Flu | Harris Teeter, LLC | DailyMed |
| Nighttime Cold and Flu | Kroger | DailyMed |
| Nighttime Cold and Flu | Rite Aid Corporation | DailyMed |
| Nighttime Cold and Flu | Walgreens | DailyMed |
Showing 25 of 49 brands.
Acetaminophen 650 mg/30 mL · Dextromethorphan hydrobromide 30 mg/30 mL · Doxylamine succinate 12.5 mg/30 mL · solution (oral) · 52 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| 24-7 Life BY 7-ELEVEN Nighttime Cold and Flu | Lil' Drug Store products, Inc. | DailyMed |
| All Nite | Major Pharmaceuticals | — |
| Basic Care Nighttime Cold and Flu | Amazon.com Services LLC | DailyMed |
| CareOne Night TIme Cold and Flu | American Sales Company | DailyMed |
| CareOne Nighttime Cold and Flu | American Sales Company | DailyMed |
| Cold and Flu | Army and Air Force Exchange Service | DailyMed |
| Cold and Flu | HyVee Inc | DailyMed |
| Cold and Flu | Walgreen Company | DailyMed |
| Cold and Flu Night | Walgreen Company | DailyMed |
| Cold and Flu Nighttime | Bi-Mart | — |
| Cold and Flu Nighttime | Cardinal Health 110, LLC. DBA Leader | DailyMed |
| Cold and Flu Nighttime | Lidl US LLC | DailyMed |
| Cold and Flu Nighttime Relief | L.N.K. International, Inc. | DailyMed |
| Cold and Flu Relief | Safeway | DailyMed |
| CVS Nighttime Cold and Flu Relief | Cvs Pharmacy | DailyMed |
| Dg Health Cold and Flu Relief | Dolgencorp Inc | DailyMed |
| Dg Health Night Time Cold and Flu Relief | Dolgencorp Inc | DailyMed |
| Equaline Nighttime Cold and Flu Relief | United Natural Foods, Inc. dba UNFI | DailyMed |
| Equate Nighttime Cold and Flu | Wal-Mart Stores Inc | DailyMed |
| Family Dollar Nighttime Cold and Flu Relief Original Flavor | Family Dollar Services Inc | — |
| Foster and Thrive Nighttime Cold and Flu Relief | Sportpharm LLC | DailyMed |
| Foster and Thrive Nighttime Cold and Flu Relief | Strategic Sourcing Services LLC | — |
| Good Neighbor Pharmacy Night Time | Amerisource Bergen | DailyMed |
| Good Neighbor Pharmacy Night Time Cold and Flu | Amerisource Bergen | DailyMed |
| Good Sense Night Time | L. Perrigo Company | DailyMed |
Showing 25 of 41 brands.
Acetaminophen 325 mg · Dextromethorphan hydrobromide 10 mg · Doxylamine succinate 6.25 mg · capsule, liquid filled (oral) · 6 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Acetaminophen, Dextromethorphan HBr and Doxylamine Succinate | Softgel Healthcare Private Limited | DailyMed |
| Acetaminophen, Dextromethorphan Hydrobromide and Doxylamine Succinate | Softgel Healthcare Private Limited | DailyMed |
| Nighttime Ultra Concentrated Cold and Flu | Walgreens | DailyMed |
| Ultra Concentrated Nighttime COLD AND FLU | PuraCap Pharmaceutical LLC | DailyMed |
| Vicks NyQuil HIGH BLOOD PRESSURE COLD and FLU | The Procter & Gamble Manufacturing Company | — |
| Vicks NyQuil ULTRA CONCENTRATED COLD and FLU | The Procter & Gamble Manufacturing Company | — |
Acetaminophen 325 mg · Dextromethorphan hydrobromide 10 mg · Doxylamine succinate 6.25 mg · tablet, coated (oral) · 6 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| NyQuil Cold and Flu w/VapoCOOL, 4ct | Select Consumer Group | — |
| NyQuil Cold and Flu w/VapoCOOL, 4ct, CVP HEALTH | Lil' Drug Store Products, Inc. | DailyMed |
| NyQuil Cold and Flu w/VapoCOOL, 4ct, Lil Drug Store | Lil' Drug Store Products, Inc. | DailyMed |
| NyQuil Cold and Flu w/VapoCOOL, 4ct, Travel BASIX | Lil' Drug Store Products, Inc. | DailyMed |
| Vicks NyQuil VapoCOOL COLD and FLU | Navajo Manufacturing Company Inc. | — |
| Vicks NyQuil VapoCOOL COLD and FLU | The Procter & Gamble Manufacturing Company | — |
Acetaminophen 325 mg · Dextromethorphan hydrobromide 15 mg · Doxylamine succinate 6.25 mg · capsule (oral) · 5 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Contac Cold and Flu | Vespyr Brands LLC | DailyMed |
| Nighttime Cold and Flu Relief | Allegiant Health | DailyMed |
| Nighttime Cold and Flu Relief | Aurohealth LLC | DailyMed |
| Nighttime Cold and Flu Relief | Chain Drug Consortium, LLC | DailyMed |
| Nighttime Cold and Flu Relief | Grocery Outlet | DailyMed |
Acetaminophen 325 mg/15 mL · Dextromethorphan hydrobromide 10 mg/15 mL · Doxylamine succinate 6.25 mg/15 mL · solution (oral) · 5 products
Acetaminophen 325 mg · Dextromethorphan hydrobromide 10 mg · Doxylamine succinate 6.25 mg · tablet, film coated (oral) · 3 products
Acetaminophen 1000 mg/30 mL · Dextromethorphan hydrobromide 30 mg/30 mL · Doxylamine succinate 12.5 mg/30 mL · liquid (oral) · 3 products
Acetaminophen 650 mg/30 mL · Dextromethorphan hydrobromide 20 mg/30 mL · Doxylamine succinate 12.5 mg/30 mL · liquid (oral) · 2 products
| Brand or product name | Company on the label | Label |
|---|---|---|
| Rompe Pecho NT NT | Efficient Laboratories Inc | DailyMed |
| Vicks NyQuil FOR PEOPLE WITH DIABETES COLD and FLU | The Procter & Gamble Manufacturing Company | — |
Acetaminophen 325 mg/15 mL · Dextromethorphan hydrobromide 10 mg/15 mL · Doxylamine succinate 6.25 mg/15 mL · liquid (oral) · 2 products
| Brand or product name | Company on the label | Label |
|---|---|---|
| Vicks NyQuil ELDERBERRY COLD and FLU | The Procter & Gamble Manufacturing Company | — |
| Vicks NyQuil Kids COLD and COUGH plus FEVER | The Procter & Gamble Manufacturing Company | — |
Acetaminophen 162.5 mg · Dextromethorphan hydrobromide 5 mg · Doxylamine succinate 3.125 mg · tablet, chewable (oral) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Mucinex Childrens Mighty Chews Night Time Cold and Flu | Reckitt Benckiser LLC | — |
Acetaminophen 325 mg/15 mL · Dextromethorphan hydrobromide 15 mg/15 mL · Doxylamine succinate 6.25 mg/15 mL · liquid (oral) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Coricidin HBP Nighttime Multi-Symptom Cold | Bayer HealthCare LLC. | DailyMed |
Acetaminophen 21.667 mg/mL · Dextromethorphan hydrobromide 1 mg/mL · Doxylamine succinate 0.4167 mg/mL · syrup (oral) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Tukol Honey Nighttime Cold and Flu | Genomma Lab USA | DailyMed |
Acetaminophen 1000 mg/30 mL · Dextromethorphan hydrobromide 30 mg/30 mL · Doxylamine succinate 12.5 mg/30 mL · solution (oral) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Nite Time Intense Flu | Meijer, Inc. | DailyMed |
Acetaminophen 325 mg · Dextromethorphan hydrobromide 15 mg · Doxylamine succinate 6.25 mg · capsule, gelatin coated (oral) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Nighttime Cold and Flu Relief Softgels Multi-Symptom | Advanced Rx LLC | DailyMed |
Acetaminophen 325 mg · Dextromethorphan hydrobromide 20 mg · Doxylamine succinate 12.5 mg · capsule, liquid filled (oral) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Sanatos Nighttime Relief | Pharmadel LLC | DailyMed |
Acetaminophen 21.67 mg/mL · Dextromethorphan hydrobromide 0.667 mg/mL · Doxylamine succinate 0.417 mg/mL · syrup (oral) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Tukol Max Action Cold and Flu Nighttime Relief | Genomma Lab USA | DailyMed |
Acetaminophen 0.65 g/237 mL · Dextromethorphan hydrobromide 0.03 g/237 mL · Doxylamine succinate 0.0125 g/237 mL · liquid (oral) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Nighttime Cold and Flu | Walgreen Company | DailyMed |
Acetaminophen 500 mg · Dextromethorphan hydrobromide 15 mg · Doxylamine succinate 6.25 mg · capsule, liquid filled (oral) · 1 product
| Brand or product name | Company on the label | Label |
|---|---|---|
| Vicks NyQuil Intense Flu Rapid Release LiquiCaps | The Procter & Gamble Manufacturing Company | — |
What pharmacies pay (NADAC)
The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.
This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.
| Strength and form | Generic or brand | Pharmacies pay |
|---|---|---|
| acetaminophen 325 mg · dextromethorphan hydrobromide 15 mg · doxylamine succinate 6.25 mg capsule, liquid filled | Generic | $0.1162 per capsule |
| acetaminophen 650 mg/30 mL · dextromethorphan hydrobromide 30 mg/30 mL · doxylamine succinate 12.5 mg/30 mL solution | Generic | $0.0112–$0.0149 per mL 8 packages, lowest to highest |
NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.
Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →
Companies that sell this medicine
The company named on the package (maker or distributor), as listed in the FDA NDC Directory, with its number of over-the-counter products of this medicine.
- The Procter & Gamble Manufacturing Company14 products
- Lil' Drug Store Products, Inc.10 products
- QUALITY CHOICE (Chain Drug Marketing Association)9 products
- Amazon.com Services LLC7 products
- Opmx LLC6 products
- Topco Associates LLC6 products
- Cvs Pharmacy6 products
- AptaPharma Inc.5 products
- Walgreens5 products
- Walgreen Company5 products
- Meijer, Inc.4 products
- Safeway, Inc.4 products
- H E B4 products
- Dolgencorp, Inc. (DOLLAR GENERAL & REXALL)4 products
- L. Perrigo Company4 products
- United Natural Foods, Inc. dba UNFI4 products
- Pharmadel LLC4 products
- WinCo Foods, LLC4 products
- Rite Aid Corporation4 products
- HyVee Inc4 products
- Dolgencorp Inc4 products
- Meijer Distribution Inc3 products
- Vivunt Pharma LLC3 products
- Softgel Healthcare Private Limited3 products
- Discount Drug Mart3 products
- Harris Teeter, LLC3 products
- Cardinal Health 110, LLC. DBA Leader3 products
- P & L Development, LLC3 products
- Salado Sales Inc.3 products
- Advanced Rx LLC3 products
Showing the 30 companies with the most products, of 89.
Recalls
No recall linked to these products (by their NDC code or label) appears in the FDA enforcement reports.
Sources
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- FDA rule for the Drug Facts label (21 CFR 201.66)
Only medicines marketed under FDA rules for nonprescription drugs (an FDA monograph or an FDA approval) are listed. Homeopathic products are not listed: the FDA does not evaluate them for safety or effectiveness.