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Over-the-counter medicine · no prescription needed

Acetaminophen, chlorpheniramine and phenylephrine

Purpose on the label: Pain reliever/fever reducer Antihistamine Nasal decongestant

Cough, cold and flu

Official FDA data, not advice

The label text is quoted exactly as the company filed it with the U.S. Food and Drug Administration (FDA), with a link to the official copy. The list of brands comes from the FDA NDC Directory.

This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.

If someone may have taken too much, call Poison Help: 1‑800‑222‑1222. In an emergency, call 911.

Quick answers

What is Acetaminophen, chlorpheniramine and phenylephrine used for?
The Drug Facts label of Allergy Multisymptom (Chain Drug Marketing Association Inc) lists these uses: temporarily relieves these symptoms of hay fever or other upper respiratory allergies: headache sinus congestion and pressure nasal congestion runny nose and sneezing minor aches and pains temporarily relieves these additional symptoms of hay fever: itching of the nose or throat itchy, watery eyes helps clear nasal passages helps decongest sinus openings and passages.
Do I need a prescription for Acetaminophen, chlorpheniramine and phenylephrine?
No. The products on this page are sold without a prescription (over the counter).
Is a store brand the same as the name brand?
Products listed together below have the same active ingredients, in the same amount and the same form, as registered with the FDA. Inactive ingredients (such as colors, flavors and fillers) and package sizes can differ. Compare the “Active ingredient” box on both packages, and ask a pharmacist if you are not sure.
Has Acetaminophen, chlorpheniramine and phenylephrine been recalled?
No recall linked to these products appears in the FDA enforcement reports we use.

Drug Facts label

Every over-the-counter medicine must carry a “Drug Facts” box in the same order, set by FDA rules. Below is the label of one product for each common strength and form, quoted word for word. Your own package can differ (for example, children’s products have other directions): always follow the label on your package.

Allergy Multisymptom · Chain Drug Marketing Association Inc

Acetaminophen 325 mg · Chlorpheniramine maleate 2 mg · Phenylephrine hydrochloride 5 mg, tablet, coated (oral)

Active ingredient (in each caplet)

Purpose Acetaminophen 325 mg Pain reliever Chlorpheniramine maleate 2 mg Antihistamine Phenylephrine HCl 5 mg Nasal decongestant

Purpose

Active ingredients (in each caplet) Purpose Acetaminophen 325 mg Pain reliever Chlorpheniramine maleate 2 mg Antihistamine Phenylephrine HCl 5 mg Nasal decongestant

Uses

temporarily relieves these symptoms of hay fever or other upper respiratory allergies: headache sinus congestion and pressure nasal congestion runny nose and sneezing minor aches and pains temporarily relieves these additional symptoms of hay fever: itching of the nose or throat itchy, watery eyes helps clear nasal passages helps decongest sinus openings and passages

Warnings

Liver warning This product contains acetaminophen. The maximum daily dose of this product is 10 caplets (3,250 mg acetaminophen) in 24 hours. Severe liver damage may occur if you take more than 4,000 mg of acetaminophen in 24 hours with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy alert Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening blisters rash If a skin reaction occurs, stop use and seek medical help right away.

Do not use

with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. if you have ever had an allergic reaction to this product or any of its ingredients

Ask a doctor before use if

you have liver disease heart disease high blood pressure thyroid disease diabetes trouble urinating due to an enlarged prostate gland a breathing problem such as emphysema or chronic bronchitis glaucoma

Ask a doctor or pharmacist before use if

you are taking sedatives or tranquilizers taking the blood thinning drug warfarin

When using this product

do not exceed recommended dosage excitability may occur, especially in children drowsiness may occur alcohol, sedatives, and tranquilizers may increase drowsiness avoid alcoholic drinks be careful when driving a motor vehicle or operating machinery

Stop use and ask a doctor if

nervousness, dizziness, or sleeplessness occur pain or nasal congestion gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur These could be signs of a serious condition.

If pregnant or breast-feeding

ask a health professional before use.

Keep out of reach of children

Overdose warning In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Directions

do not take more than directed (see overdose warning )

adults and children 12 years and over
  • take 2 caplets every 4 hours
  • swallow whole; do not crush, chew, or dissolve
  • do not take more than 10 caplets in 24 hours
children under 12 years
  • ask a doctor

Inactive ingredients

acesulfame potassium, colloidal silicon dioxide, corn starch, croscarmellose sodium, crospovidone, flavor, iron oxide yellow, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone, pregelatinized starch, propylene glycol, stearic acid, talc, titanium dioxide

— FDA label of Allergy Multisymptom, Chain Drug Marketing Association Inc, effective December 2, 2024. See the official label on DailyMed →

Cold Medicine XL3 · Selder, S.A. de C.V.

Acetaminophen 325 mg · Chlorpheniramine maleate 2 mg · Phenylephrine hydrochloride 5 mg, tablet (oral)

Active ingredient (in each tablet)

Acetaminophen 325 mg Chlorpheniramine maleate 2 mg Phenylepherine HCl 5 mg

Purpose

Pain reliever/fever reducer Antihistamine Nasal decongestant

Uses

temporarily relieves

  • minor aches and pains
  • headaches
  • nasal congestion
  • sinus congestion & pressure
  • runny nose
  • sneezing

Warnings

  • Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take
  • more than 12 tablets in 24 hours, which is the maximum daily amount
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product Alergy alert acetaminophen may cause severe skin reactions. Symptoms may include
  • skin reddening
  • blisters
  • rash If a skin reaction occurs, stop use and seek medical help right away

Do not use

  • If you are allergic to acetaminophen
  • more than 10 days unless directed by a doctor
  • if you are taking a monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson"s disease) or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. Ask adoctor before use if you have
  • liver disease
  • heart disease
  • glaucoma
  • high blood pressure
  • thyroid disease
  • diabetes
  • trouble urinating due to enlarged prostate gland
  • a breathing problem such as emphysema or chronic bronchitis

Ask a doctor or pharmacist before use if

you

  • are taking the blood thinning drug warfarin
  • are taking sedatives or tranquilizers

When using this product

  • do not use more than directed
  • excitability may occur, especially in children
  • may cause drowsiness
  • alcohol, sedatives and tranquilizers may increase drowsiness
  • avoid alcoholic drinks
  • be careful when driving a motor vehicle or operating machinery

Stop use and ask a doctor if

  • redness or swelling is present
  • new symptoms occur
  • you get nervous, dizzy, or sleepless
  • pain or nasal congestion gets worse or lasts for more than 7 days
  • fever gets worse or lasts for more than 3 days

Keep out of reach of children

If pregnant or breast-feeding

ask a health professional before use.

Keep out of reach of children

In case of overdose, get medical help or contact a Poison Control Center (1-800-222-1222) immediately.Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Directions

  • Do not use more than directed
  • Adults and children 12 years of age and older: take 2 tablets every 4 hours. Do not take more than 12 tablets in 24 hours
  • Children under 12 years of age: do not use in children under 12 years of age; this will provide more than the recommended dose (overdoes) and may cause liver damage.

Inactive ingredients

alcohol, croscarmellose sodium, hypromellose, lactose monhydrate (derived from milk), magnesium stearate, polyethylene glycol, purified water, talc, titanium dioxide

Questions?

and Comments? 1-855-259-1590 Monday through Friday 9AM-5PM EST

— FDA label of Cold Medicine XL3, Selder, S.A. de C.V., effective October 17, 2024. See the official label on DailyMed →

PhysiciansCare Allergy Multi-Symptom Relief · Acme United Corporation

Acetaminophen 325 mg · Chlorpheniramine maleate 2 mg · Phenylephrine hydrochloride 5 mg, tablet, film coated (oral)

Active ingredient (in each tablet)

Acetaminophen 325 mg Chlorpheniramine Maleate 2 mg Phenylephrine Hydrochloride 5 mg

Purpose

Pain reliever/fever reduecer Antihistamine Nasal decongestant

Uses

temporarily relieves these symptoms of hay fever or other upper respiratory allergies nasal congestion headache itchy, watery eyes itching of the nose and throat running nose and sneezing minor aches and pains sinus congestion and pressure

Warnings

  • Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take:
  • more than 4,000 mg of acetaminophen in 24 hours, which is the maximum daily amount
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product
  • Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include:
  • skin reddening
  • blisters
  • rash If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • for more than 10 days for pain unless directed by a doctor
  • for more than 3 days for fever unless directed by a doctor
  • with any other drug using the above active ingredients
  • if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.

Ask a doctor before use if

you have

  • liver disease
  • thyroid disease
  • diabetes
  • high blood pressure
  • heart disease
  • glaucoma
  • chronic bronchitis or emphysema
  • difficulty in urination due to enlargement of the prostate gland

Ask a doctor or pharmacist before use if

you are

  • taking the blood thinning drug warfarin
  • taking sedatives or tranquilizers

When using this product

  • drowsiness may occur
  • avoid alcoholic beverages
  • alcohol, sedatives and tranquilizers may increase the drowsiness effect
  • use caution when driving a motor vehicle or operating machinery
  • excitability may occur, especially in children

Stop use and ask a doctor if

  • symptoms do not improve within 7 days or are accompanied by a fever
  • pain or fever persists or gets worse
  • any new symptoms appear
  • redness or swelling is present

If pregnant or breast-feeding

ask a health professional before use. Keep out of the reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Directions

do not use more than directed Adults and children: (12 years and older) Take 2 tablets every 4 hours. Do not take more than 12 tablets in 24 hours. Children under 12 years: Do not give to children under 12 years of age.

Inactive ingredients

corn starch, crospovidone, hypromellose, microcrystalline cellulose, polyethylene glycol, povidone, pregelatinized starch, stearic acid

Questions?

1-800-835-2263

— FDA label of PhysiciansCare Allergy Multi-Symptom Relief, Acme United Corporation, effective September 8, 2025. See the official label on DailyMed →

Pentrexcilina Daytime · Opmx LLC

Acetaminophen 500 mg · Chlorpheniramine maleate 4 mg · Phenylephrine hydrochloride 10 mg, tablet (oral)

Active ingredient (in each tablet)

Acetaminophen 500 mg Chlorpheniramine Maleate 4 mg Phenylephrine HCl 10 mg

Purpose

Pain Reliever/Fever Reducer Antihistamine Nasal decongestant

Uses

temporarily relieves these symptoms of hay fever or other respiratory allergies: headache sinus congestion & pressure nasal congestion runny nose and sneezing minor aches & pain temporarily relieves these additional symptoms of hay fever: nose or throat itching itchy, watery eyes helps clear nasal passages helps decongest sinus opening and passages

Warnings

  • Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take : more than 6 tablets in 24 hours, which is the maximum daily amount for this product with other drugs contains acetaminophen 3 or more alcoholic drinks every day while using this product.
  • Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening blisters rash If a skin reaction occurs, stop use and seek medical help right away.
  • Sore throat warning: if sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult doctor promptly

Do not use

with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. if you have ever had an allergic reaction to this product or any of its ingredients to make a child sleepy

Ask a doctor before use if

you have: liver disease heart disease high blood pressure thyroid disease glaucoma diabetes trouble urinating due to enlarged prostate gland a breathing problem such as emphysema or chronic bronchitis

Ask a doctor or pharmacist before use if

you are: taking the blood thinning drug warfarin taking sedatives or tranquilizers

When using this product

do not use more than directed excitability may occur, especially in children drowsiness may occur alcohol, sedatives and tranquilizers may increase drowsiness avoid alcoholic drinks be careful when driving a motor vehicle or operating machinery

Stop use and ask a doctor if

nervousness, dizziness, or sleeplessness occur pain or nasal congestion gets worse or lasts more than 7 days fever gets worse or last more than 3 days redness or swelling is present new symptoms occur These could be signs of a serious condition.

If pregnant or breast-feeding

ask a health professional before use.

Keep out of reach of children

  • Overdose warning: Taking more than directed can cause serious health problems. In case of overdose, get medical help or contact a Poison Control Center right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Directions

Do not take more than directed - see overdose warning Swallow whole; do not crush, chew or dissolve Do not exceed 6 tablets per 24 hours

Adults and children 12 years of age & over1 tablet with water every 4-6 hours as needed
Children 4 to 12 years of ageAsk a doctor
Children under 4 years of ageDo not use

Inactive ingredients

Microcrystalline cellulose, Polyvinylpyrrolidone, Crospovidone, Magnesium stearate, Colloidal silicon dioxide, Purified talc

Questions?

Call: (619) 600-5632 (Mon-Fri 9am-5pm EST) or https://www.opmx.us

— FDA label of Pentrexcilina Daytime, Opmx LLC, effective July 15, 2026. See the official label on DailyMed →

Cold Medicine XL3 FORTE · Selder, S.A. de C.V.

Acetaminophen 325 mg · Chlorpheniramine maleate 4 mg · Phenylephrine hydrochloride 10 mg, tablet (oral)

Active ingredient (in each tablet)

Acetaminophen 325 mg Chlorpheniramine maleate 4 mg Phenylepherine HCl 10 mg

Purpose

Pain reliever/fever reducer Antihistamine Nasal decongestant

Uses

temporarily relieves

  • minor aches and pains
  • headaches
  • nasal congestion
  • sinus congestion & pressure
  • runny nose
  • sneezing

Warnings

  • Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take
  • more than 6 tablets in 24 hours, which is the maximum daily amount
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product Alergy alert acetaminophen may cause severe skin reactions. Symptoms may include
  • skin reddening
  • blisters
  • rash If a skin reaction occurs, stop use and seek medical help right away

Do not use

  • If you are allergic to acetaminophen
  • more than 10 days unless directed by a doctor
  • for more than 3 days for fever unless directed by a doctor
  • if you are taking a monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson"s disease) or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contasins an MAOI, ask a doctor or pharmacist before taking this product.
  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. Ask adoctor before use if you have
  • liver disease
  • heart disease
  • glaucoma
  • high blood pressure
  • thyroid disease
  • diabetes
  • trouble urinating due to enlarged prostate gland
  • a breathing problem such as emphysema or chronic bronchitis

Ask a doctor or pharmacist before use if

you

  • are taking the blood thinning drug warfarin
  • are taking sedatives or tranquilizers

When using this product

  • do not use more than directed
  • excitability may occur, especially in children
  • may cause drowsiness
  • alcohol, sedatives and tranquilizers may increase drowsiness
  • avoid alcoholic drinks
  • be careful when driving a motor vehicle or operating machinery

Stop use and ask a doctor if

  • redness or swelling is present
  • new symptoms occur
  • you get nervous, dizzy, or sleepless
  • pain or nasal congestion gets worse or lasts for more than 7 days
  • fever gets worse or lasts for more than 3 days

Keep out of reach of children

If pregnant or breast-feeding

ask a health professional before use.

Keep out of reach of children

Overdose warning : Taking more than the recommended dose (overdose) may cause liver damage. In case of overdose, get medical help or contact a Poison Control Center (1-800-222-1222) right away.Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Directions

  • Do not use more than directed (see overdose warning)
  • Adults and children 12 years of age and older: take 1 tablet every 4 hours Do not take more than 6 tablets in 24 hours
  • Children under 12 years of age: do not use because this product contains to much medication for children under this age.

Inactive ingredients

Lactose monohydrate (derived from milk), Stearic acid, Povidone, Alcohol, Water purified, Hypromellose, Titanium dioxide, Triacetin, contains FDC Yellow No. 5 (tartrazine) as color additive

Questions?

and Comments? You may report side effects to 1-855-259-1590 Monday through Friday 9AM-5PM EST

— FDA label of Cold Medicine XL3 FORTE, Selder, S.A. de C.V., effective October 24, 2024. See the official label on DailyMed →

Norel AD · U.S. Pharmaceutical Corporation

Acetaminophen 325 mg · Chlorpheniramine maleate 4 mg · Phenylephrine hydrochloride 10 mg, tablet, multilayer (oral)

Active ingredient (per tablet)

Acetaminophen 325 mg Chlorpheniramine Maleate 4 mg Phenylephrine HCl 10 mg

Purpose

Pain reliever Antihistamine Nasal decongestant

Uses

Temporarily relieves these symptoms due to the common cold or flu nasal congestion runny nose minor aches and pains headache sore throat sneezing itchy, watery eyes itching of the nose or throat sinus congestion and pressure temporarily reduces fever

Warnings

  • Liver warning: This product contains acetaminophen. Severe liver damage may occur if adult takes more than 6 tablets in 24 hours, which is the maximum daily amount child takes more than 5 doses in 24 hours taken with other drugs containing acetaminophen adult has 3 or more alcoholic drinks every day while using this product
  • Allergy alert: Acetaminophen may cause severe skin reaction. Symptoms may include: skin reddening blisters rash If a skin reaction occurs, stop use and seek medical help right away.
  • Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea or vomiting, speak with a healthcare provider.

Do not use

with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product

Ask a doctor before use if

you have liver disease heart disease high blood pressure thyroid disease diabetes glaucoma trouble urinating due to an enlarged prostate gland a breathing problem such as emphysema or chronic bronchitis

Ask a doctor or pharmacist before use if

you are taking the blood thinning drug warfarin taking any other nasal decongestant or stimulant taking sedatives or tranquilizers

When using this product

do not exceed recommended dosage drowsiness may occur avoid alcoholic beverages alcohol, sedatives, and tranquilizers may increase drowsiness be careful when driving a motor vehicle or operating machinery excitability may occur, especially in children

Stop use and ask a doctor if

pain or nasal congestion gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present you get nervous, dizzy, or sleepless new symptoms occur If pregnant or breast feeding ask a health professional before use Keep out of the reach of children. Taking more than the recommended dose can cause serious health problems. In case of overdose, get medical help or contact Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Directions

do not take more than directed (see overdose warning) adults and children 12 years of age and over: take 1 tablet every 4 hours, while symptoms persist do not take more than 6 tablets in 24 hours, unless directed by a doctor children under 12 years of age: ask a doctor

Inactive ingredients

Colloidal Silicon Dioxide, Crospovidone Polyplasdone, Magnesium Stearate (vegetable base), Microcrystalline Cellulose, Povidone K-30, Pregelatinized Starch, Stearic Acid, D&C Yellow #10, FD&C Yellow #6.

Questions?

Please visit www.uspco.com or contact us at US Pharmaceutical Corporation, P.O. Box 360465, Decatur, GA 30036

— FDA label of Norel AD, U.S. Pharmaceutical Corporation, effective October 17, 2025. See the official label on DailyMed →

This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.

Same medicine, other brands

Each group lists the products that have exactly the same active ingredients, in the same amount and form, as registered with the FDA (NDC Directory). A store brand in the same group has the same medicine as the name brand; inactive ingredients, flavors and package sizes can differ. Each product links to its own official label.

Acetaminophen 325 mg · Chlorpheniramine maleate 2 mg · Phenylephrine hydrochloride 5 mg · tablet, coated (oral) · 13 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Allergy Multi Symptom Aaa Pharmaceutical, Inc. DailyMed
Allergy Multi Symptom Amerisource Bergen DailyMed
Allergy Multi Symptom Chain Drug Marketing Association, Inc. DailyMed
Allergy Multi Symptom Goodsense DailyMed
Allergy Multi Symptom Heb DailyMed
Allergy Multi Symptom Marc Glassman, Inc. DailyMed
Allergy Multi Symptom Topco Associates LLC DailyMed
Allergy Multi-Symptom Strategic Sourcing Services LLC DailyMed
Allergy Multisymptom Chain Drug Marketing Association Inc DailyMed
Allergy Multisymptom Discount Drug Mart DailyMed
Allergy MultiSymptom Retail Business Services, LLC. DailyMed
Multi-Symptom Allergy Walgreen Company DailyMed
Relief-PE HART Health DailyMed
Acetaminophen 325 mg · Chlorpheniramine maleate 2 mg · Phenylephrine hydrochloride 5 mg · tablet (oral) · 11 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Allergy Sinus, Lil Drug Store Lil' Drug Store Products, Inc. DailyMed
Cold Medicine Allegiant Health DailyMed
Cold Medicine Selder, S.A. de C.V. DailyMed
Cold Medicine XL3 Midway Importing, Inc. DailyMed
Cold Medicine XL3 Selder, S.A. de C.V. DailyMed
Coltalin Fortune Pharmacal Company Limited —
Defensol D Menper Distributors, Inc. DailyMed
Extra Fast Coltalin Fortune Pharmacal Company Limited —
FLONASE Headache and Allergy Relief Haleon US Holdings LLC DailyMed
Acetaminophen 325 mg · Chlorpheniramine maleate 2 mg · Phenylephrine hydrochloride 5 mg · tablet, film coated (oral) · 7 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Allergy Multi-Symptom Army and Air Force Exchange Service DailyMed
Allergy Multi-Symptom Cardinal Health 110, LLC. DBA Leader DailyMed
Allergy Multi-Symptom Dolgencorp, LLC DailyMed
Allergy Multi-Symptom L.N.K. International, Inc. DailyMed
Medique Medicidin D Unifirst First Aid Corporation DailyMed
Otis Clapp Valihist Unifirst First Aid Corporation DailyMed
PhysiciansCare Allergy Multi-Symptom Relief Acme United Corporation DailyMed
Acetaminophen 500 mg · Chlorpheniramine maleate 4 mg · Phenylephrine hydrochloride 10 mg · tablet (oral) · 6 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Acetaminophen, Chlorpheniramine Maleate, Phenylephrine HCl Opmx LLC DailyMed
Coldtac Ultra Opmx LLC —
Desenfriol D Opmx LLC —
Pentrexcilina Daytime Opmx LLC DailyMed
Resfriol D Opmx LLC DailyMed
Acetaminophen 325 mg · Chlorpheniramine maleate 4 mg · Phenylephrine hydrochloride 10 mg · tablet (oral) · 2 products

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Cold Medicine XL3 FORTE Midway Importing Inc. DailyMed
Cold Medicine XL3 FORTE Selder, S.A. de C.V. DailyMed
Acetaminophen 325 mg · Chlorpheniramine maleate 4 mg · Phenylephrine hydrochloride 10 mg · tablet, multilayer (oral) · 1 product

Drug Facts for this strength and form ↑

Brand or product nameCompany on the labelLabel
Norel AD U.S. Pharmaceutical Corporation DailyMed
Acetaminophen 325 mg · Chlorpheniramine maleate 4 mg · Phenylephrine hydrochloride 10 mg · capsule (oral) · 1 product
Brand or product nameCompany on the labelLabel
Antiflu Des Cough and Flu Productos Farmaceuticos, S.A. de C.V. DailyMed
Acetaminophen 325 mg · Chlorpheniramine maleate 2 mg · Phenylephrine hydrochloride 5 mg · tablet, effervescent (oral) · 1 product
Brand or product nameCompany on the labelLabel
Antigrip Extra Strength Pharmadel LLC DailyMed

What pharmacies pay (NADAC)

The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.

This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.

NADAC per unit for Acetaminophen, chlorpheniramine and phenylephrine, by strength and form
Strength and formGeneric or brandPharmacies pay
acetaminophen 325 mg · chlorpheniramine maleate 2 mg · phenylephrine hydrochloride 5 mg
tablet, coated
Generic $0.0850 per tablet
acetaminophen 325 mg · chlorpheniramine maleate 2 mg · phenylephrine hydrochloride 5 mg
tablet, film coated
Generic $0.0850 per tablet

NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.

Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →

Companies that sell this medicine

The company named on the package (maker or distributor), as listed in the FDA NDC Directory, with its number of over-the-counter products of this medicine.

  • Opmx LLC6 products
  • Fortune Pharmacal Company Limited4 products
  • Selder, S.A. de C.V.3 products
  • Midway Importing, Inc.2 products
  • Unifirst First Aid Corporation2 products
  • Chain Drug Marketing Association Inc2 products
  • L.N.K. International, Inc.1 product
  • Dolgencorp, LLC1 product
  • Goodsense1 product
  • Heb1 product
  • Acme United Corporation1 product
  • Discount Drug Mart1 product
  • Army and Air Force Exchange Service1 product
  • Allegiant Health1 product
  • HART Health1 product
  • U.S. Pharmaceutical Corporation1 product
  • Menper Distributors, Inc.1 product
  • Aaa Pharmaceutical, Inc.1 product
  • Walgreen Company1 product
  • Strategic Sourcing Services LLC1 product
  • Topco Associates LLC1 product
  • Haleon US Holdings LLC1 product
  • Marc Glassman, Inc.1 product
  • Productos Farmaceuticos, S.A. de C.V.1 product
  • Retail Business Services, LLC.1 product
  • Pharmadel LLC1 product
  • Amerisource Bergen1 product
  • Lil' Drug Store Products, Inc.1 product
  • Cardinal Health 110, LLC. DBA Leader1 product

Recalls

No recall linked to these products (by their NDC code or label) appears in the FDA enforcement reports.

Sources

  1. Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  2. NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  3. Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
  4. FDA rule for the Drug Facts label (21 CFR 201.66)

Only medicines marketed under FDA rules for nonprescription drugs (an FDA monograph or an FDA approval) are listed. Homeopathic products are not listed: the FDA does not evaluate them for safety or effectiveness.

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