Quick answers
- What is Acetaminophen and guaifenesin used for?
- The Drug Facts label of Maximum Strength Mucus Relief Plus Pain and Headache (Shield Pharmaceuticals Corp) lists these uses: temporarily relieves these common cold and flu symptoms: minor aches and pains headache sore throat helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive temporarily reduces fever.
- Do I need a prescription for Acetaminophen and guaifenesin?
- No. The products on this page are sold without a prescription (over the counter).
- Is a store brand the same as the name brand?
- Products listed together below have the same active ingredients, in the same amount and the same form, as registered with the FDA. Inactive ingredients (such as colors, flavors and fillers) and package sizes can differ. Compare the “Active ingredient” box on both packages, and ask a pharmacist if you are not sure.
- Has Acetaminophen and guaifenesin been recalled?
- No recall linked to these products appears in the FDA enforcement reports we use.
Drug Facts label
Every over-the-counter medicine must carry a “Drug Facts” box in the same order, set by FDA rules. Below is the label of one product for each common strength and form, quoted word for word. Your own package can differ (for example, children’s products have other directions): always follow the label on your package.
Maximum Strength Mucus Relief Plus Pain and Headache · Shield Pharmaceuticals Corp
Acetaminophen 325 mg · Guaifenesin 200 mg, capsule, liquid filled (oral)
Active ingredient (in each softgel)
Acetaminophen 325 mg Guaifenesin 200 mg
Purpose
Pain reliever/fever reducer Expectorant
Uses
temporarily relieves these common cold and flu symptoms: minor aches and pains headache sore throat helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive temporarily reduces fever
Warnings
- Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: more than 4,000 mg of acetaminophen in 24 hours with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this produc t
- Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening blisters rash If a skin reaction occurs, stop use and seek medical help right away.
- Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.
Do not use
with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
Ask a doctor before use if
you have liver disease persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema cough that occurs with too much phlegm (mucus)
Ask a doctor or pharmacist before use if
you are taking the blood thinning drug warfarin
When using this product
do not use more than directed
Stop use and ask a doctor if
pain or cough gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur cough comes back, or occurs with rash or headache that lasts. These could be signs of a serious condition.
If pregnant or breast-feeding
ask a health professional before use.
Keep out of reach of children
Directions
do not take more than directed (see Overdose warning) do not take more than 12 softgels in any 24-hour period adults and children 12 years of age and over: take 2 softgels every 4 hours children under 12 years of age: do not use
Other information
store at 20-25ºC (68-77ºF) avoid excessive heat
Inactive ingredients
FD&C blue no. 1, gelatin, glycerin, hypromellose, lecithin, light mineral oil, polyethylene glycol, povidone, propylene glycol, purified water, sorbitol sorbitan solution, titanium dioxide
Questions?
1-800-373-6981 (toll-free)
— FDA label of Maximum Strength Mucus Relief Plus Pain and Headache, Shield Pharmaceuticals Corp, effective May 6, 2026. See the official label on DailyMed →
Tylenol Cold Plus Flu Plus Chest Congestion · Kenvue Brands LLC
Acetaminophen 325 mg · Guaifenesin 200 mg, tablet, film coated (oral)
Active ingredient (in each caplet)
Acetaminophen 325 mg Guaifenesin 200 mg
Purpose
Pain reliever/fever reducer Expectorant
Uses
- temporarily relieves these common cold/flu symptoms:
- minor aches and pains
- headache
- sore throat
- helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive
- temporarily reduces fever
Warnings
- Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take
- more than 4,000 mg of acetaminophen in 24 hours
- with other drugs containing acetaminophen
- 3 or more alcoholic drinks every day while using this product Allergy alert acetaminophen may cause severe skin reactions. Symptoms may include:
- skin reddening
- blisters
- rash If a skin reaction occurs, stop use and seek medical help right away. Sore throat warning If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.
Do not use
- with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
- if you have ever had an allergic reaction to this product or any of its ingredients
Ask a doctor before use if
you have
- liver disease
- persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis or emphysema
- cough that occurs with too much phlegm (mucus)
Ask a doctor or pharmacist before use if
you are taking the blood thinning drug warfarin
When using this product
do not exceed recommended dose
Stop use and ask a doctor if
- pain or cough gets worse or lasts more than 7 days
- fever gets worse or lasts more than 3 days
- redness or swelling is present
- new symptoms occur
- cough comes back or occurs with rash or headache that lasts These could be signs of a serious condition.
If pregnant or breast-feeding
ask a health professional before use.
Keep out of reach of children
Directions
do not take more than directed (see overdose warning)
| Adults and children 12 years and over: | ■ take 2 caplets every 4 hours while symptoms last ■ do not take more than 10 caplets in 24 hours |
| Children under 12 years: | ■ ask a doctor |
Inactive ingredients
croscarmellose sodium, flavor, hydroxypropyl cellulose, hypromellose, magnesium stearate, microcrystalline cellulose, pregelatinized starch, titanium dioxide, triacetin
Questions?
call 1-877-895-3665 (toll-free) or 215-273-8755 (collect).
— FDA label of Tylenol Cold Plus Flu Plus Chest Congestion, Kenvue Brands LLC, effective April 8, 2026. See the official label on DailyMed →
Mucinex Fast-Max Cold, Flu and Sore Throat · Reckitt Benckiser LLC
Acetaminophen 325 mg · Guaifenesin 200 mg, tablet (oral)
Active ingredient (in each caplet)
Acetaminophen 325 mg Guaifenesin 200mg
Purpose
Active ingredients Purposes (in each caplet) Acetaminophen 325 mg...Pain reliever/fever reducer Guaifenesin 200mg..............................Expectorant
Uses
- temporarily relieves these common cold and flu symptoms:
- minor aches and pains
- headache
- sore throat
- helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive
- temporarily reduces fever
Warnings
- Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take:
- more than 12 caplets in 24 hours, which is the maximum daily amount for this product
- with other drugs containing acetaminophen
- 3 or more alcoholic drinks daily while using this product Allergy alert : Acetaminophen may cause severe skin reactions. Symptoms may include:
- skin reddening
- blisters
- rash If a skin reaction occurs, stop use and seek medical help right away.
- Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.
Do not use
- with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
Ask a doctor before use if
you have
- liver disease
- persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema
- cough that occurs with too much phlegm (mucus)
Ask a doctor or pharmacist before use if
you are taking the blood thinning drug warfarin
When using this product
do not use more than directed
Stop use and ask a doctor if
- pain or cough gets worse or lasts more than 7 days
- fever gets worse or lasts more than 3 days
- redness or swelling is present
- new symptoms occur
- cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition
If pregnant or breast-feeding
ask a health professional before use.
Keep out of reach of children
- Overdose warning: Taking more than the recommended dose (overdose) may cause liver damage. In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Directions
do not take more than directed (see Overdose warning ) do not take more than 12 caplets in any 24-hour period adults and children 12 years of age and older: take 2 caplets every 4 hours children under 12 years of age: do not use
Inactive ingredients
croscarmellose sodium, FD&C red no. 40 aluminum lake, FD&C yellow no. 6 aluminum lake, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone, talc, titanium dioxide
Questions?
1-866-MUCINEX (1-866-682-4639) You may also report side effects to this phone number.
— FDA label of Mucinex Fast-Max Cold, Flu and Sore Throat, Reckitt Benckiser LLC, effective May 20, 2026. See the official label on DailyMed →
Coricidin HBP Maximum Strength Cold Flu And Chest Congestion · Bayer HealthCare LLC.
Acetaminophen 325 mg · Guaifenesin 200 mg, capsule, gelatin coated (oral)
Active ingredient (in each tablet)
Purpose Acetaminophen 325 mg Pain reliever/ fever reducer Guaifenesin 200 mg Expectorant
Purpose
Active ingredients (in each tablet) Purpose Acetaminophen 325 mg Pain reliever/ fever reducer Guaifenesin 200 mg Expectorant
Uses
temporarily relieves these symptoms due to a cold or flu: minor aches and pains headache sore throat helps loosen phlegm(mucus) and thin bronchial secretions to make coughs more productive temporarily reduces fever
Warnings
- Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take
- more than 4,000 mg of acetaminophen in 24 hours
- with other drugs containing acetaminophen
- 3 or more alcoholic drinks every day while using this product
- Allergy alert: Acetaminophen may cause severe skin or severe allergic reactions. Symptoms may include:
- skin reddening
- blisters
- rash
- hives
- facial swelling
- asthma (wheezing)
- shock If a skin or general allergic reaction occurs, stop use and seek medical help right away.
- Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly
Do not use
- with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
- if you have ever had an allergic reaction to this product or any of its ingredients
- in children under 12 years of age
Ask a doctor before use if
you have
- liver disease
- persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema
- cough that is accompanied by excessive phlegm (mucus)
Ask a doctor or pharmacist before use if
you are taking the blood thinning drug warfarin
Stop use and ask a doctor if
- pain or cough gets worse or lasts more than 7 days
- fever gets worse or lasts more than 3 days
- redness or swelling is present
- new symptoms occur
- cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition.
If pregnant or breast-feeding
ask a health professional before use.
Keep out of reach of children
In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Directions
- do not take more than the recommended dose
- adults and children 12 years and over: take 2 capsules with water every 4 hours. Do not exceed 10 capsules in 24 hours or as directed by a doctor.
- children under 12 years of age: do not use
Inactive ingredients
FD&C yellow # 6, gelatin, glycerin, iron oxide black, lecithin, medium-chain triglycerides, mica, polyethylene glycol, potassium aluminum silicate, povidone, propylene glycol,purified water, shellac, sodium hydroxide, sorbitol sorbitan solution,titanium dioxide
Questions?
? Questions or comments? 1-800-317-2165 (Mon-Fri 9AM -5PM EST)
— FDA label of Coricidin HBP Maximum Strength Cold Flu And Chest Congestion, Bayer HealthCare LLC., effective December 4, 2025. See the official label on DailyMed →
Mucinex Childrens Mini Melts Cold and Flu · Reckitt Benckiser LLC
Acetaminophen 162.5 mg · Guaifenesin 100 mg, granule (oral)
Active ingredient (in each packet)
Acetaminophen 162.5 mg Guaifenesin 100 mg Active ingredients (in each packet) Purposes Acetaminophen 162.5 mg Fever Reducer/Pain Reliever Guaifenesin 100 mg Expectorant
Purpose
Active ingredients (in each packet) Purposes Acetaminophen 162.5 mg Fever Reducer/Pain Reliever Guaifenesin 100 mg Expectorant
Uses
Temporarily relieves minor aches and pains due to:
- the common cold
- flu
- headache
- sore throat
- temporarily reduces fever
- helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive
Warnings
Liver warning : This product contains acetaminophen. Severe liver damage may occur if
- adult takes more than 6 doses (24 packets) in 24 hours, which is the maximum daily amount
- child takes more than 5 doses (10 packets) in 24 hours, which is the maximum daily amount
- taken with other drugs containing acetaminophen
- adult has 3 or more alcoholic drinks every day while using this product Allergy alert : Acetaminophen may cause severe skin reactions. Symptoms may include:
- skin reddening
- blister
- rash If a skin reaction occurs, stop use and seek medical help right away.
- Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting; consult a doctor promptly.
Do not use
with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
Ask a doctor before use if
you have
Ask a doctor before use if
the user has
- liver disease
- persistent or chronic cough that lasts such as occurs with smoking, asthma, chronic bronchitis, or emphysema
- cough accompanied by too much phlegm (mucus)
Ask a doctor or pharmacist before use if
the user is taking the blood thinning drug warfarin
When using this product
do not use more than directed
Stop use and ask a doctor if
- pain or cough gets worse or lasts more than 5 days (children) or 7 days (adults)
- fever gets worse or lasts more than 3 days
- redness or swelling is present
- new symptoms occur
- cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition.
If pregnant or breast-feeding
ask a health professional before use.
Keep out of reach of children
In case of overdose, get medical help or contact a Poison Control Center right away.
Directions
empty entire contents of packet onto tongue and swallow for best taste, do not chew granules
| Age | Dose |
|---|---|
| adults and Children 12 years of age and over | 2 to 4 packets every 4 hours, not to exceed 6 doses (24 packets) in 24 hours |
| children 6 years to under 12 years of age | 2 packets every 4 hours, not to exceed 5 doses (10 packets) in 24 hours |
| children under 6 years of age | do not use |
Inactive ingredients
amino methacrylate copolymer, carbomer homopolymer type A, carboxymethylcellulose sodium, hypromellose, magnesium stearate, microcrystalline cellulose, povidone, colloidal silicon dioxide, simethicone, sodium bicarbonate, sorbitol, sodium lauryl sulphate, sucralose, stearic acid, strawberry flavor, talc, triethyl citrate, vanilla flavor
Questions?
1-866-682-4639 You may also report side effects to this phone number.
— FDA label of Mucinex Childrens Mini Melts Cold and Flu, Reckitt Benckiser LLC, effective May 19, 2026. See the official label on DailyMed →
This page is not medical advice. Read the label on your package, and ask a pharmacist or doctor if you are not sure a medicine is right for you, for your child, or with your other medicines.
Same medicine, other brands
Each group lists the products that have exactly the same active ingredients, in the same amount and form, as registered with the FDA (NDC Directory). A store brand in the same group has the same medicine as the name brand; inactive ingredients, flavors and package sizes can differ. Each product links to its own official label.
Acetaminophen 325 mg · Guaifenesin 200 mg · capsule, liquid filled (oral) · 6 products
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Daytime | Cvs Health Corp | DailyMed |
| Maximum Strength Mucus Relief Plus Pain and Headache | Shield Pharmaceuticals Corp | DailyMed |
| Mucinex Cold and Flu | Reckitt Benckiser LLC | — |
| Mucinex Cold, Flu, and Sore Throat | Reckitt Benckiser LLC | — |
| Mucinex Sinus Max Clear and Cool | RB Health (US) LLC | DailyMed |
| Vicks Sinex Severe PAIN, MUCUS and CHEST CONGESTION | The Procter & Gamble Manufacturing Company | — |
Acetaminophen 325 mg · Guaifenesin 200 mg · tablet, film coated (oral) · 3 products
Acetaminophen 325 mg · Guaifenesin 200 mg · tablet (oral) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Mucinex Fast-Max Cold, Flu and Sore Throat | Reckitt Benckiser LLC | DailyMed |
Acetaminophen 325 mg · Guaifenesin 200 mg · capsule, gelatin coated (oral) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Coricidin HBP Maximum Strength Cold Flu And Chest Congestion | Bayer HealthCare LLC. | DailyMed |
Acetaminophen 162.5 mg · Guaifenesin 100 mg · granule (oral) · 1 product
Drug Facts for this strength and form ↑
| Brand or product name | Company on the label | Label |
|---|---|---|
| Mucinex Childrens Mini Melts Cold and Flu | Reckitt Benckiser LLC | DailyMed |
Companies that sell this medicine
The company named on the package (maker or distributor), as listed in the FDA NDC Directory, with its number of over-the-counter products of this medicine.
- Reckitt Benckiser LLC5 products
- Cvs Woonsocket Prescription Center, Incorporated1 product
- Kenvue Brands LLC1 product
- The Procter & Gamble Manufacturing Company1 product
- Cvs Health Corp1 product
- RB Health (US) LLC1 product
- Shield Pharmaceuticals Corp1 product
- Bayer HealthCare LLC.1 product
Recalls
No recall linked to these products (by their NDC code or label) appears in the FDA enforcement reports.
Sources
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- FDA rule for the Drug Facts label (21 CFR 201.66)
Only medicines marketed under FDA rules for nonprescription drugs (an FDA monograph or an FDA approval) are listed. Homeopathic products are not listed: the FDA does not evaluate them for safety or effectiveness.