Quick answers
- What is Perphenazine used for?
- The FDA-approved label (Perphenazine, Remedyrepack Inc., August 27, 2026) says: “Perphenazine is indicated for use in the treatment of schizophrenia and for the control of severe nausea and vomiting in adults. Perphenazine has not been shown effective for the management of behavioral complications in patients with mental retardation.” This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or change any medicine.
- Does Perphenazine have a boxed warning?
- Yes. The FDA label for Perphenazine has a boxed warning, the FDA’s strongest warning. Read it on the full label and ask your pharmacist.
- Is there a shortage of Perphenazine?
- No current shortage is listed by the FDA for the products of this medicine (FDA data from October 30, 2026).
- Has Perphenazine been recalled?
- No recall linked to the products of this medicine appears in the FDA enforcement reports we use.
- Who makes Perphenazine?
- 16 companies list prescription products of Perphenazine in the FDA NDC Directory, including Bryant Ranch Prepack, Remedyrepack Inc. and Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc..
What Perphenazine is used for
Quoted from the “Indications and Usage” section of the FDA-approved label.
Perphenazine is indicated for use in the treatment of schizophrenia and for the control of severe nausea and vomiting in adults. Perphenazine has not been shown effective for the management of behavioral complications in patients with mental retardation.
— FDA label: Perphenazine, Remedyrepack Inc., effective August 27, 2026. Read the full label on DailyMed →
The FDA has 35 labels for products of this medicine (different makers and forms); uses can differ between them. Check the label that comes with your own medicine.
This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or change any medicine.
Conditions named on the label
These condition names appear word for word in the label’s “Indications and Usage” text (matched with a reviewed table). Each page lists hospitals whose own websites name the condition.
Related medical specialties
Boxed warning
A boxed warning (“black box”) is the FDA’s strongest warning on a drug label, for serious or life-threatening risks.
This label has a boxed warning. Read it on the full label →
35 of 35 FDA labels for this medicine have a boxed warning.
Forms and how it is given
| Dosage forms | Tablet, film coated · Tablet |
|---|---|
| Route | Oral |
| Prescription products | 73 in the FDA NDC Directory |
What pharmacies pay (NADAC)
The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.
This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.
| Strength and form | Generic or brand | Pharmacies pay |
|---|---|---|
| perphenazine 16 mg tablet | Generic | $0.3818 per tablet |
| perphenazine 16 mg tablet, film coated | Generic | $0.3818 per tablet |
| perphenazine 2 mg tablet | Generic | $0.1719 per tablet |
| perphenazine 2 mg tablet, film coated | Generic | $0.1719 per tablet |
| perphenazine 4 mg tablet | Generic | $0.1774 per tablet |
| perphenazine 4 mg tablet, film coated | Generic | $0.1774 per tablet |
| perphenazine 8 mg tablet | Generic | $0.1060 per tablet |
| perphenazine 8 mg tablet, film coated | Generic | $0.1060 per tablet |
NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.
Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →
Companies that list this medicine
Labelers in the FDA NDC Directory: the company named on the package (maker or distributor), with the number of prescription products.
- Bryant Ranch Prepack14 products
- Remedyrepack Inc.9 products
- Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.4 products
- Rising Pharma Holdings, Inc.4 products
- Sandoz Inc4 products
- Golden State Medical Supply, Inc.4 products
- Wilshire Pharmaceuticals, Inc.4 products
- Zydus Lifesciences Limited4 products
- Proficient Rx LP4 products
- Par Health USA, LLC4 products
- Zydus Pharmaceuticals USA Inc.4 products
- Macleods Pharmaceuticals Limited4 products
- Actavis Pharma, Inc.4 products
- Major Pharmaceuticals3 products
- American Health Packaging2 products
- Chartwell RX, LLC1 product
FDA approval history
- ANDA: Abbreviated New Drug Application: how a generic version is approved.
Generic approvals (8)
- ANDA089685Sandoz · December 8, 1988
- ANDA040226Ph Health · December 31, 1998
- ANDA205973Wilshire Pharms Inc · December 17, 2015
- ANDA207582Watson Labs Inc · October 17, 2016
- ANDA205056Rising · March 1, 2019
- ANDA205232Zydus Pharms · April 6, 2020
- ANDA210163Somerset Theraps LLC · May 18, 2022
- ANDA212545Macleods Pharms · May 6, 2024
Shortage status
The FDA drug shortage list does not show these products.
Recalls
No recall linked to these products (by their NDC code) appears in the FDA enforcement reports.
Official identifiers
| RxCUI (RxNorm) | 198075, 198076, 198077, 198078 |
|---|---|
| SPL set ID of the quoted label | c4150683-0772-4344-bb1c-f050b84175d6 |
| FDA labels (SPL) | 35 |
| FDA applications | 8 ANDA |
| Active ingredients (FDA) | PERPHENAZINE |
Sources
- FDA-approved label on DailyMed (National Library of Medicine) — Perphenazine, Remedyrepack Inc., effective August 27, 2026; via openFDA, FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- Drug shortages (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
openFDA data is provided by the FDA as is; it may be incomplete. Always rely on the label that comes with your medicine. FDA Enforcement Report search →