Quick answers
- What is Isocarboxazid used for?
- The FDA-approved label (Marplan, Lifsa Drugs LLC, April 21, 2026) says: “Marplan is indicated for the treatment of depression. Because of its potentially serious side effects, Marplan is not an antidepressant of first choice in the treatment of newly diagnosed depressed patients. The efficacy of Marplan in the treatment of depression was established in 6-week controlled trials of depressed outpatients. …” This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or change any medicine.
- Does Isocarboxazid have a boxed warning?
- Yes. The FDA label for Marplan has a boxed warning, the FDA’s strongest warning. Read it on the full label and ask your pharmacist.
- Is there a shortage of Isocarboxazid?
- The FDA drug shortage list shows “Current shortage” for a product of this medicine (updated August 6, 2026). Ask your pharmacist about alternatives.
- Has Isocarboxazid been recalled?
- No recall linked to the products of this medicine appears in the FDA enforcement reports we use.
- Who makes Isocarboxazid?
- 1 company lists prescription products of Isocarboxazid in the FDA NDC Directory, including Lifsa Drugs LLC.
What Isocarboxazid is used for
Quoted from the “Indications and Usage” section of the FDA-approved label.
Marplan is indicated for the treatment of depression. Because of its potentially serious side effects, Marplan is not an antidepressant of first choice in the treatment of newly diagnosed depressed patients. The efficacy of Marplan in the treatment of depression was established in 6-week controlled trials of depressed outpatients. …
— FDA label: Marplan, Lifsa Drugs LLC, effective April 21, 2026. Read the full label on DailyMed →
This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or change any medicine.
Conditions named on the label
These condition names appear word for word in the label’s “Indications and Usage” text (matched with a reviewed table). Each page lists hospitals whose own websites name the condition.
Related medical specialties
Boxed warning
A boxed warning (“black box”) is the FDA’s strongest warning on a drug label, for serious or life-threatening risks.
This label has a boxed warning. Read it on the full label →
Forms and how it is given
| Dosage forms | Tablet |
|---|---|
| Route | Oral |
| Prescription products | 1 in the FDA NDC Directory |
| Brand names | Marplan |
Companies that list this medicine
Labelers in the FDA NDC Directory: the company named on the package (maker or distributor), with the number of prescription products.
- Lifsa Drugs LLC1 product
FDA approval history
- NDA: New Drug Application: how a new (usually brand-name) medicine is approved.
| Application | Sponsor | Approved | Later changes approved |
|---|---|---|---|
| NDA011961 MARPLAN | Lifsa Drugs | July 1, 1959 | 10, latest November 8, 2018 2018: Labeling · 2016: Manufacturing (CMC) · 2007: Labeling |
Shortage status
Current shortage · updated August 6, 2026 · first posted April 16, 2026
| Product | Marplan, Tablet, 10 mg, 100 count bottle (NDC 72336-032-01) |
|---|---|
| Availability | Limited Availability |
| Reason given | Other |
| Company | Lifsa Drugs LLC |
Ask your pharmacist whether your product is affected and what the options are.
Recalls
No recall linked to these products (by their NDC code) appears in the FDA enforcement reports.
Official identifiers
| RxCUI (RxNorm) | 104837, 201708 |
|---|---|
| SPL set ID of the quoted label | 95fde749-44ad-4668-86c4-0ff17bca0074 |
| FDA labels (SPL) | 1 |
| FDA applications | NDA011961 |
| Active ingredients (FDA) | ISOCARBOXAZID |
Sources
- FDA-approved label on DailyMed (National Library of Medicine) — Marplan, Lifsa Drugs LLC, effective April 21, 2026; via openFDA, FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- Drug shortages (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
openFDA data is provided by the FDA as is; it may be incomplete. Always rely on the label that comes with your medicine. FDA Enforcement Report search →