Quick answers
- What is Chlorzoxazone used for?
- The FDA-approved label (Chlorzoxazone, Par Health USA, LLC, August 31, 2026) says: “Chlorzoxazone tablets are indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute, painful musculoskeletal conditions. The mode of action of this drug has not been clearly identified, but may be related to its sedative properties. Chlorzoxazone does not directly relax tense skeletal muscles in man.” This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or change any medicine.
- Does Chlorzoxazone have a boxed warning?
- No. None of the 26 FDA labels we found for this medicine has a boxed warning.
- Is there a shortage of Chlorzoxazone?
- No current shortage is listed by the FDA for the products of this medicine (FDA data from October 30, 2026).
- Has Chlorzoxazone been recalled?
- No recall linked to the products of this medicine appears in the FDA enforcement reports we use.
- Who makes Chlorzoxazone?
- 19 companies list prescription products of Chlorzoxazone in the FDA NDC Directory, including Bryant Ranch Prepack, Rising Pharma Holdings, Inc. and Advanced Rx of Tennessee, LLC.
What Chlorzoxazone is used for
Quoted from the “Indications and Usage” section of the FDA-approved label.
Chlorzoxazone tablets are indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute, painful musculoskeletal conditions. The mode of action of this drug has not been clearly identified, but may be related to its sedative properties. Chlorzoxazone does not directly relax tense skeletal muscles in man.
— FDA label: Chlorzoxazone, Par Health USA, LLC, effective August 31, 2026. Read the full label on DailyMed →
The FDA has 26 labels for products of this medicine (different makers and forms); uses can differ between them. Check the label that comes with your own medicine.
This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or change any medicine.
Boxed warning
A boxed warning (“black box”) is the FDA’s strongest warning on a drug label, for serious or life-threatening risks.
The label quoted above has no boxed warning.
0 of 26 FDA labels for this medicine have a boxed warning.
Forms and how it is given
| Dosage forms | Tablet |
|---|---|
| Route | Oral |
| Prescription products | 36 in the FDA NDC Directory |
What pharmacies pay (NADAC)
The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.
This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.
| Strength and form | Generic or brand | Pharmacies pay |
|---|---|---|
| chlorzoxazone 250 mg tablet | Generic | $2.52 per tablet |
| chlorzoxazone 375 mg tablet | Generic | $0.6665 per tablet |
| chlorzoxazone 500 mg tablet | Generic | $0.2192 per tablet |
| chlorzoxazone 750 mg tablet | Generic | $0.6519 per tablet |
NADAC list of November 4, 2026; these prices took effect between July 22, 2026 and October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.
Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →
Companies that list this medicine
Labelers in the FDA NDC Directory: the company named on the package (maker or distributor), with the number of prescription products.
- Bryant Ranch Prepack5 products
- Rising Pharma Holdings, Inc.4 products
- Advanced Rx of Tennessee, LLC3 products
- Aurobindo Pharma Limited3 products
- Sportpharm LLC3 products
- A-S Medication Solutions2 products
- Cintex Services, LLC2 products
- Par Health USA, LLC2 products
- Proficient Rx LP2 products
- Lifsa Drugs LLC1 product
- Solubiomix1 product
- Remedyrepack Inc.1 product
- Advanced Rx Pharmacy of Tennessee, LLC1 product
- Happy Robin, LLC1 product
- Mayne Pharma Commercial LLC1 product
- Camber Pharmaceuticals, Inc.1 product
- PD-Rx Pharmaceuticals, Inc.1 product
- Actavis Pharma, Inc.1 product
- Novitium Pharma LLC1 product
FDA approval history
- ANDA: Abbreviated New Drug Application: how a generic version is approved.
Generic approvals (11)
- ANDA089853Aurobindo Pharma Ltd · May 4, 1988
- ANDA089859Watson Labs · May 4, 1988
- ANDA207483Pharmobedient · June 24, 2016
- ANDA212254Novitium Pharma · September 12, 2019
- ANDA211849DR Reddys Labs SA · July 21, 2020
- ANDA212743Ph Health · November 2, 2020
- ANDA215158Pharmazone · July 29, 2021
- ANDA213126Rising · April 5, 2022
- ANDA214702Macleods Pharms · April 10, 2023
- ANDA216925Rising · August 9, 2023
- ANDA210961Pharmazone · January 22, 2024
Shortage status
The FDA drug shortage list does not show these products.
Recalls
No recall linked to these products (by their NDC code) appears in the FDA enforcement reports.
Official identifiers
| RxCUI (RxNorm) | 197501, 197502, 1088934, 1088936 |
|---|---|
| SPL set ID of the quoted label | 7c5a835d-3754-4c25-a0e2-335b8eceb2d2 |
| FDA labels (SPL) | 26 |
| FDA applications | 11 ANDA |
| Active ingredients (FDA) | CHLORZOXAZONE |
Sources
- FDA-approved label on DailyMed (National Library of Medicine) — Chlorzoxazone, Par Health USA, LLC, effective August 31, 2026; via openFDA, FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- Drug shortages (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
openFDA data is provided by the FDA as is; it may be incomplete. Always rely on the label that comes with your medicine. FDA Enforcement Report search →