Quick answers
- Does Carbon dioxide have a boxed warning?
- No. None of the 36 FDA labels we found for this medicine has a boxed warning.
- Is there a shortage of Carbon dioxide?
- No current shortage is listed by the FDA for the products of this medicine (FDA data from October 30, 2026).
- Has Carbon dioxide been recalled?
- No recall linked to the products of this medicine appears in the FDA enforcement reports we use.
- Who makes Carbon dioxide?
- 34 companies list prescription products of Carbon dioxide in the FDA NDC Directory, including Maine Oxy-Acetylene Supply Company, Roberts Oxygen Company, Inc. and General Air Service & Supply Co.
What Carbon dioxide is used for
We did not find an “Indications and Usage” section in the FDA labels for this medicine. See the label on DailyMed →
This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or change any medicine.
Boxed warning
A boxed warning (“black box”) is the FDA’s strongest warning on a drug label, for serious or life-threatening risks.
The label quoted above has no boxed warning.
0 of 36 FDA labels for this medicine have a boxed warning.
Forms and how it is given
| Dosage forms | Gas |
|---|---|
| Route | Respiratory (inhalation) |
| Prescription products | 40 in the FDA NDC Directory |
| Brand names | Carbon Dioxide Refrigerated |
Companies that list this medicine
Labelers in the FDA NDC Directory: the company named on the package (maker or distributor), with the number of prescription products.
- Maine Oxy-Acetylene Supply Company3 products
- Roberts Oxygen Company, Inc.2 products
- General Air Service & Supply Co2 products
- A-OX Welding Supply, LLC2 products
- Airgas USA, LLC2 products
- Haun Specialty Gases, Inc.1 product
- Medical-Technical Gases, Inc.1 product
- ILMO Products Company1 product
- Airgas Therapeutics, LLC1 product
- Norco, Inc1 product
- Machine & Welding Supply Company dba Arc3 Gases South1 product
- Air Source Industries Inc1 product
- Messer Merchant Production LLC1 product
- Linde Inc.1 product
- NexAir, LLC1 product
- Keen Compressed Gas Co. Inc.1 product
- MITCHELL WELDING SUPPLY DBA Meritus Texas1 product
- WSM Supplier LLC.1 product
- AGL Inhalation Therapy Co.1 product
- Red Ball Oxygen Co., Inc.1 product
- Linde Gas & Equipment Inc.1 product
- Welders Supply Company of Louisville, Inc.1 product
- American Welding & Gas, Inc.1 product
- Messer Gas Puerto Rico, Inc1 product
- Central Welding Supply Company1 product
- Aero All Gas Company1 product
- Oxarc, LLC1 product
- DJB Gas Services, Inc1 product
- Westair Gases & Equipment, Inc.1 product
- Messer LLC1 product
- Matheson Tri-Gas, Inc.1 product
- Holston Gases, Inc1 product
- Arcet Equipment Company dba Arc3 Gases North1 product
- Reliant Holdings, Ltd1 product
FDA approval history
- NDA: New Drug Application: how a new (usually brand-name) medicine is approved.
| Application | Sponsor | Approved | Later changes approved |
|---|---|---|---|
| NDA205764 CARBON DIOXIDE, USP | Linde North America Inc | July 5, 2013 | — |
| NDA205815 CARBON DIOXIDE, USP | Linde Merchant Productions Inc | July 5, 2013 | — |
| NDA205846 CARBON DIOXIDE, USP | Airgas Carbonic Inc | July 20, 2013 | — |
| NDA205852 CARBON DIOXIDE, USP | Praxair Inc | July 21, 2013 | — |
| NDA206025 CARBON DIOXIDE, USP | Airgas USA LLC | September 7, 2013 | — |
| NDA207166 CARBON DIOXIDE, USP | Reliant Holdings Ltd | May 25, 2014 | — |
| NDA213507 CARBON DIOXIDE, USP | A-Ox Welding Supply Co, Inc. | June 15, 2019 | — |
| NDA215007 CARBON DIOXIDE, USP | Nexair LLC | July 18, 2020 | — |
| NDA217082 CARBON DIOXIDE, USP | Continental Carbonic Products, Inc. | February 25, 2022 | — |
| NDA219303 CARBON DIOXIDE, USP | Haun Specialty Gases Inc | February 17, 2024 | — |
| NDA219779 CARBON DIOXIDE, USP | Central Welding Supply | August 10, 2024 | — |
| NDA220050 Carbon Dioxide, USP | Djb Gas Services, Inc | November 9, 2024 | — |
| NDA220266 Carbon Dioxide, USP | Welders Supply Company of Louisville Inc | February 2, 2025 | — |
| NDA220461 CARBON DIOXIDE, USP | Mitchell Wedling Supply | April 21, 2025 | — |
Shortage status
The FDA drug shortage list does not show these products.
Recalls
No recall linked to these products (by their NDC code) appears in the FDA enforcement reports.
Official identifiers
| RxCUI (RxNorm) | 308998, 309002, 309004, 347023, 347024, 347967, 541999, 1091094, 1728767, 1790649 |
|---|---|
| SPL set ID of the quoted label | 77f13272-8e40-8f92-92dd-dcb5aad0219d |
| FDA labels (SPL) | 36 |
| FDA applications | NDA205764, NDA205815, NDA205846, NDA205852, NDA206025, NDA207166, NDA213507, NDA215007, NDA217082, NDA219303, NDA219779, NDA220050, NDA220266, NDA220461 |
| Active ingredients (FDA) | CARBON DIOXIDE |
Sources
- FDA-approved label on DailyMed (National Library of Medicine) — Carbon Dioxide Refrigerated, Messer LLC, effective February 16, 2026; via openFDA, FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- Drug shortages (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
openFDA data is provided by the FDA as is; it may be incomplete. Always rely on the label that comes with your medicine. FDA Enforcement Report search →