Quick answers
- What is Calcitriol used for?
- The FDA-approved label (Vectical, Galderma Laboratories, L.P., October 24, 2024) says: “VECTICAL Ointment is a vitamin D analog indicated for the topical treatment of mild to moderate plaque psoriasis in adult and pediatric patients 2 years and older. Limitations of Use The safety and effectiveness of VECTICAL Ointment in patients with known or suspected disorders of calcium metabolism have not been evaluated. …” This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or change any medicine.
- Does Calcitriol have a boxed warning?
- No. None of the 31 FDA labels we found for this medicine has a boxed warning.
- Is there a shortage of Calcitriol?
- The FDA drug shortage list shows “To be discontinued” for a product of this medicine (updated December 4, 2025). Ask your pharmacist about alternatives.
- Has Calcitriol been recalled?
- FDA enforcement reports list 1 recall of products of this medicine; the newest started May 1, 2014 (Class II). A recall usually concerns specific lots, not every product.
- Who makes Calcitriol?
- 24 companies list prescription products of Calcitriol in the FDA NDC Directory, including Bryant Ranch Prepack, Aphena Pharma Solutions - Tennessee, LLC and Chartwell RX, LLC.
What Calcitriol is used for
Quoted from the “Indications and Usage” section of the FDA-approved label.
VECTICAL Ointment is a vitamin D analog indicated for the topical treatment of mild to moderate plaque psoriasis in adult and pediatric patients 2 years and older. Limitations of Use The safety and effectiveness of VECTICAL Ointment in patients with known or suspected disorders of calcium metabolism have not been evaluated. …
— FDA label: Vectical, Galderma Laboratories, L.P., effective October 24, 2024. Read the full label on DailyMed →
The FDA has 31 labels for products of this medicine (different makers and forms); uses can differ between them. Check the label that comes with your own medicine.
This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or change any medicine.
Boxed warning
A boxed warning (“black box”) is the FDA’s strongest warning on a drug label, for serious or life-threatening risks.
The label quoted above has no boxed warning.
0 of 31 FDA labels for this medicine have a boxed warning.
Forms and how it is given
| Dosage forms | Capsule · Capsule, liquid filled · Solution · Injection · Ointment |
|---|---|
| Route | Oral · Intravenous · Topical |
| Prescription products | 42 in the FDA NDC Directory |
| Brand names | Vectical |
What pharmacies pay (NADAC)
The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.
This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.
| Strength and form | Generic or brand | Pharmacies pay |
|---|---|---|
| calcitriol 0.25 ug capsule | Generic | $0.1507 per capsule |
| calcitriol 0.25 ug capsule, liquid filled | Generic | $0.1507 per capsule |
| calcitriol 0.5 ug capsule | Generic | $0.2300 per capsule |
| calcitriol 0.5 ug capsule, liquid filled | Generic | $0.2300 per capsule |
| calcitriol 1 ug/mL solution | Generic | $6.22 per mL |
NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.
Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →
Companies that list this medicine
Labelers in the FDA NDC Directory: the company named on the package (maker or distributor), with the number of prescription products.
- Bryant Ranch Prepack6 products
- Aphena Pharma Solutions - Tennessee, LLC3 products
- Chartwell RX, LLC2 products
- Epic Pharma, LLC2 products
- A-S Medication Solutions2 products
- Golden State Medical Supply, Inc.2 products
- Hikma Pharmaceuticals USA Inc.2 products
- Sun Pharmaceutical Industries, Inc.2 products
- Amneal Pharmaceuticals LLC2 products
- Bionpharma Inc.2 products
- Teva Pharmaceuticals USA, Inc.2 products
- Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.2 products
- Strides Pharma Science Limited2 products
- Patrin Pharma, Inc.1 product
- Fosun Pharma USA Inc.1 product
- Padagis Israel Pharmaceuticals Ltd1 product
- Rising Pharma Holdings, Inc.1 product
- Remedyrepack Inc.1 product
- ANI Pharmaceuticals, Inc.1 product
- American Health Packaging1 product
- Gland Pharma Limited1 product
- Cardinal Health 107, LLC1 product
- Galderma Laboratories, L.P.1 product
- PD-Rx Pharmaceuticals, Inc.1 product
FDA approval history
- NDA: New Drug Application: how a new (usually brand-name) medicine is approved.
- ANDA: Abbreviated New Drug Application: how a generic version is approved.
| Application | Sponsor | Approved | Later changes approved |
|---|---|---|---|
| NDA021068 ROCALTROL | Esjay Pharma | November 20, 1998 | 3, latest May 15, 2013 2013: Manufacturing (CMC) · 2004: Labeling · 2002: Labeling |
| NDA022087 VECTICAL | Galderma Labs LP | January 23, 2009 | 1, latest July 17, 2020 2020: Efficacy |
Generic approvals (11)
- ANDA075765Teva · October 12, 2001
- ANDA076242Hikma · July 18, 2003
- ANDA076917Hikma · March 27, 2006
- ANDA091174Bionpharma · May 24, 2013
- ANDA091356Onesource Specialty · December 12, 2014
- ANDA203289Amneal Pharms · June 14, 2017
- ANDA209798Rising · November 21, 2018
- ANDA204556Sun Pharm · February 21, 2019
- ANDA211030Gland · February 3, 2020
- ANDA203973Anda Repository · July 28, 2023
- ANDA219796Humanwell Puracap · February 27, 2026
Shortage status
To be discontinued · updated December 4, 2025 · first posted December 4, 2025
| Product | Calcitriol, Capsule, .25 ug (NDC 0093-7352-01) |
|---|---|
| Company | Teva Pharmaceuticals USA, Inc. |
Ask your pharmacist whether your product is affected and what the options are.
Recalls
From FDA enforcement reports, matched by the product’s NDC code. A recall usually covers specific lots only: check the lot number on your package and ask your pharmacist. Do not stop a medicine on your own.
-
May 1, 2014 · Class II · Terminated · D-1427-2014
Failed Impurity/Degradation Specification; out of specification for trans-calcitriol degradant at the 9 month stability time point
Calcitriol Oral Solution 1 mcg/mL, 15mL bottle, Rx only, Roxane Laboratories, Inc., Columbus, Ohio 43216, NDC 0054-3120-41. — Boehringer Ingelheim Roxane Inc
What do the recall classes mean?
Class I: The most serious type: there is a reasonable chance that using the product will cause serious health problems or death.
Class II: Using the product may cause temporary or medically reversible health problems, or the chance of serious problems is remote.
Class III: Using the product is not likely to cause health problems (for example a labeling or packaging issue).
Official identifiers
Sources
- FDA-approved label on DailyMed (National Library of Medicine) — Vectical, Galderma Laboratories, L.P., effective October 24, 2024; via openFDA, FDA data exported October 30, 2026, retrieved October 31, 2026
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- Drug shortages (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
openFDA data is provided by the FDA as is; it may be incomplete. Always rely on the label that comes with your medicine. FDA Enforcement Report search →