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Internal Medicine

Melanie S. Greene, MD

Works at hospitals in Greenville, SC · Greer, SC · Simpsonville, SC · South Carolina

Summary

Dr. Melanie S. Greene, MD is an internal medicine doctor at 201 N Main St, Greenville, SC 29601. Phone: (864) 603-5600. Accepts Medicare assignment. In 2024, Melanie S. Greene had 341 Original Medicare patients and 11,766 services. NPI 1922056647. Source: CMS National Downloadable File, updated October 2, 2026; CMS Facility Affiliation Data, updated October 2, 2026; CMS Medicare Physician & Other Practitioners, data year 2024.

From official Medicare data

This page shows what Medicare's official clinician data says about Melanie S. Greene, joined by NPI number (data updated October 2, 2026). It is not a recommendation or a rating. Call the office or hospital to confirm before you go.

In a medical emergency, call 911.

Quick answers

Does Melanie S. Greene accept Medicare assignment?
Yes. Medicare's clinician data says Melanie S. Greene accepts Medicare assignment (the Medicare-approved amount as full payment for covered services), as of October 2, 2026. Ask the office to confirm before your visit.
How many Medicare patients does Melanie S. Greene see?
In 2024, CMS data shows 341 Original Medicare patients and 11,766 services for Melanie S. Greene. This counts Original Medicare only and measures volume, not quality.
What is Melanie S. Greene's NPI number?
1922056647. The NPI (National Provider Identifier) is the clinician's permanent federal ID; you can look it up in the official NPI Registry.

Medicare activity in 2024

Official CMS public-use data for Melanie S. Greene, data year 2024 (released May 21, 2026). It covers Original Medicare (fee-for-service) patients only, not Medicare Advantage or other insurance. It shows volume, not quality or outcomes. CMS hides any count of 10 or fewer patients.

Original Medicare patients341
Services billed to Medicare11,766
Different services or procedures78
Participating Medicare providerYes
Average age of these patients74

Most frequent services

  1. Established patient office or other outpatient visit with moderate level of decision making, if using time, 30 minutes or more (99214)629 services
  2. Visit complexity inherent to evaluation and management associated with medical care services that serve as the continuing focal point for all needed health care services and/or with medical care services that are part of ongoing care related to a patient's (G2211)545 services
  3. Insertion of needle into vein for collection of blood sample (36415)467 services
  4. Magnesium level (83735)432 services
  5. Blood test, lipids (cholesterol and triglycerides) (80061)430 services

Chronic conditions among these patients

Share of this clinician’s Original Medicare patients with each condition, as published by CMS (it describes the patients, not the care given).

  • High blood pressure75%
  • High cholesterol72%
  • Arthritis42%
  • Anxiety26%
  • Diabetes21%
  • Ischemic heart disease21%

Hospitals where Melanie S. Greene works

Medicare's Facility Affiliation Data lists Melanie S. Greene at these hospitals (updated October 2, 2026). Each hospital page shows its address, phone, emergency services, Medicare rating and all its clinicians. Star rating and emergency services: Hospital General Information (CMS), data updated October 26, 2026.

Practice locations

Addresses where Melanie S. Greene is enrolled with Medicare (CMS data updated October 2, 2026).

Group practices

Medicare enrollment lists Melanie S. Greene as a member of this group (CMS data updated October 2, 2026).

  • MUSC Affiliate Physicians48 clinicians in the group

Specialties

Find other Internal Medicine doctors in South Carolina →

Other internal medicine doctors in Greenville

Clinicians with the same Medicare primary specialty in Greenville, SC — not a recommendation.

All internal medicine doctors in Greenville →

Other clinicians in MUSC Affiliate Physicians

Medicare enrollment lists these clinicians in the same group practice — not a recommendation.

Clinician information

CredentialMD
Medical schoolUniversity Of North Carolina At Chapel Hill School Of Medicine
Graduation year1994 (32 years since medical school)
Gender (as listed)Female
Medicare assignmentAccepts (Medicare-approved amount as full payment)
TelehealthOffers telehealth services
NPI (National Provider Identifier)1922056647
CorrectionsReport an error or suggest an update →

Most corrections must be made at the source: clinicians update their NPI Registry record (NPPES) and their Medicare enrollment (PECOS); this page follows the next data release.

Sources

  1. Facility Affiliation Data — Centers for Medicare & Medicaid Services (CMS), data updated October 2, 2026, retrieved October 29, 2026
  2. Hospital General Information — CMS, data updated October 26, 2026, retrieved November 13, 2026
  3. National Downloadable File (Doctors and Clinicians) — CMS, data updated October 2, 2026, retrieved October 29, 2026
  4. Medicare Physician & Other Practitioners - by Provider — CMS, data year 2024, released May 21, 2026; Medicare Physician & Other Practitioners - by Provider and Service
  5. NPI Registry — U.S. Department of Health and Human Services (NPPES), the clinician’s official record
  6. Medicare Care Compare — official Medicare tool to look up clinicians